Diazaquinomycins E-G, novel diaza-anthracene analogs from a marine-derived Streptomyces sp.

Marine Drugs

Volumn 12, Issue 6, 2014, Pages 3574-3586

  Mullowney, Michael W ^a   Ó hAinmhire, Eoghainín ^a   Shaikh, Anam ^a   Wei, Xiaomei ^a   Tanouye, Urszula ^a   Santarsiero, Bernard D ^a   Burdette, Joanna E ^a   Murphy, Brian T ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Actinomycete; Diazaquinomycin; Marine; Ovarian cancer; OVCAR5; Streptomyces

Indexed keywords

ANTHRACENE DERIVATIVE; DIAZAQUINOMYCIN E; DIAZAQUINOMYCIN F; DIAZAQUINOMYCIN G; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; QUINONE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CELL CYCLE ARREST; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG ISOLATION; DRUG MECHANISM; DRUG STRUCTURE; LC 50; NONHUMAN; PROTEIN CLEAVAGE; STREPTOMYCES; CHEMISTRY; CRYSTALLIZATION; DRUG EFFECTS; DRUG RESISTANCE; FEMALE; HUMAN; ISOLATION AND PURIFICATION; LD 50; METABOLISM; OVARIAN NEOPLASMS; PATHOLOGY; SECONDARY METABOLISM; TUMOR CELL LINE; X RAY DIFFRACTION;

ANTHRACENES; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CRYSTALLIZATION; DNA DAMAGE; DRUG RESISTANCE, NEOPLASM; FEMALE; HUMANS; LETHAL DOSE 50; OVARIAN NEOPLASMS; POLY(ADP-RIBOSE) POLYMERASES; QUINONES; SECONDARY METABOLISM; STREPTOMYCES; X-RAY DIFFRACTION;

EID: 84903516694     PISSN: None     EISSN: 16603397     Source Type: Journal    
DOI: 10.3390/md12063574     Document Type: Article

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