Bet v 1 from birch pollen is a lipocalin-like protein acting as allergen only when devoid of iron by promoting Th2 lymphocytes

Journal of Biological Chemistry

Volumn 289, Issue 25, 2014, Pages 17416-17421

  Roth Walter, Franziska ^a   Gomez Casado, Cristina ^b   Pacios, Luis F ^b   Mothes Luksch, Nadine ^c   Roth, Georg A ^d   Singer, Josef ^d   Diaz Perales, Araceli ^b   Jensen Jarolim, Erika ^a,d  

^a UNIVERSITY OF VETERINARY MEDICINE   (Austria)

^b UNIVERSIDAD POLITÉCNICA DE MADRID   (Spain)

^c AllergyCare   (Austria)

^d MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGENS; ALLERGIES; IRON; PROTEINS;

ALLERGENICITY; IMMUNE RESPONSE; IMMUNOMODULATORY; MOLECULAR BASIS; POLLEN ALLERGEN; PROTEIN FAMILY; SIDEROPHORES; STRUCTURAL EVIDENCE;

T-CELLS;

BET V 1 PROTEIN; INTERLEUKIN 13; IRON; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; POLLEN ANTIGEN; UNCLASSIFIED DRUG;

ALLERGENICITY; ARTICLE; BINDING AFFINITY; BIRCH POLLEN; CD3+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; COMPLEX FORMATION; CONTROLLED STUDY; DISSOCIATION CONSTANT; HUMAN; HUMAN CELL; IMMUNOCOMPETENT CELL; IMMUNOMODULATION; IMMUNOREGULATION; LIGAND BINDING; POLLEN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; SENSITIZATION; TH2 CELL;

ALLERGEN; ALLERGIC SENSITIZATION; ALLERGY; APO- AND HOLO-FORM; BET V 1; IMMUNOSUPPRESSION; IRON; MUCOSAL IMMUNOLOGY; SIDEROPHORE; TH2 SKEWING;

ACUTE-PHASE PROTEINS; ANTIGENS, PLANT; BETULA; CELLS, CULTURED; FEMALE; HUMANS; HYPERSENSITIVITY; IRON; LIPOCALINS; MALE; PROTO-ONCOGENE PROTEINS; STRUCTURAL HOMOLOGY, PROTEIN; TH2 CELLS;

EID: 84903478886     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.567875     Document Type: Article

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