Does prolonged pituitary down-regulation with gonadotropin-releasing hormone agonist improve the live-birth rate in in vitro fertilization treatment?

Fertility and Sterility

Volumn 102, Issue 1, 2014, Pages 75-81

  Ren, Jianzhi ^a   Sha, Aiguo ^a   Han, Dongmei ^a   Li, Ping ^a   Geng, Jie ^a   Ma, Chaihui ^a  

^a The Affiliated Chenggong Hospital of Xiamen University   (China)

Author keywords

Controlled ovarian hyperstimulation; gonadotropin releasing hormone agonist (GnRH A); in vitro fertilization

Indexed keywords

CHORIONIC GONADOTROPIN; GONADORELIN AGONIST; LUTEINIZING HORMONE;

ADULT; ARTICLE; COHORT ANALYSIS; COMPARATIVE STUDY; DOWN REGULATION; EMBRYO TRANSFER; FEMALE; FERTILIZATION IN VITRO; HUMAN; HYPOPHYSIS; INTERVENTION STUDY; LIVE BIRTH; LUTEINIZING HORMONE BLOOD LEVEL; MAJOR CLINICAL STUDY; OOCYTE; OUTCOME ASSESSMENT; OVARY HYPERSTIMULATION; PRIORITY JOURNAL; RETROSPECTIVE STUDY; UNIVERSITY HOSPITAL;

CONTROLLED OVARIAN HYPERSTIMULATION; GONADOTROPIN RELEASING HORMONE AGONIST (GNRH-A); IN VITRO FERTILIZATION;

ADULT; BIOLOGICAL MARKERS; CHORIONIC GONADOTROPIN; EMBRYO IMPLANTATION; EMBRYO TRANSFER; FEMALE; FERTILITY AGENTS, FEMALE; FERTILIZATION IN VITRO; GONADOTROPIN-RELEASING HORMONE; HOSPITALS, UNIVERSITY; HUMANS; INFERTILITY; LIVE BIRTH; LUTEINIZING HORMONE; OVULATION INDUCTION; PITUITARY GLAND; PREGNANCY; PREGNANCY RATE; RETROSPECTIVE STUDIES; TIME FACTORS; TREATMENT OUTCOME; TRIPTORELIN PAMOATE;

EID: 84903383563     PISSN: 00150282     EISSN: 15565653     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2014.03.030     Document Type: Article

References (44)

1. E. Caspi, R. Ron-El, A. Golan, H. Nachum, A. Herman, and Y. Soffer et al. Results of in vitro fertilization and embryo transfer by combined long-Acting gonadotropin-releasing hormone analog D-Trp-6-luteinizing hormone-releasing hormone and gonadotropins Fertil Steril 51 1989 95 99
2. H.C. Liu, Y.M. Lai, O. Davis, A.S. Berkeley, M. Graf, and J. Grifo et al. Improved pregnancy outcome with gonadotropin releasing hormone agonist (GnRH-A) stimulation is due to the improvement in oocyte quantity rather than quality J Assist Reprod Genet 9 1992 338 344
3. R. Depalo, K. Jayakrishan, G. Garruti, I. Totaro, M. Panzarino, and F. Giorgino et al. GnRH agonist versus GnRH antagonist in in vitro fertilization and embryo transfer (IVF/ET) Reprod Biol Endocrinol 10 2012 26
4. D. de Ziegler, B. Borghese, and C. Chapron Endometriosis and infertility: pathophysiology and management Lancet 376 2010 730 738
5. K. Barnhart, R. Dunsmoor-Su, and C. Coutifaris Effect of endometriosis on in vitro fertilization Fertil Steril 77 2002 1148 1155
6. K. Nakamura, M. Oosawa, I. Kondou, S. Inagaki, H. Shibata, and O. Narita et al. Menotropin stimulation after prolonged gonadotropin releasing hormone agonist pretreatment for in vitro fertilization in patients with endometriosis J Assist Reprod Genet 9 1992 113 117
7. E.S. Surrey, K.M. Silverberg, M.W. Surrey, and W.B. Schoolcraft Effect of prolonged gonadotropin-releasing hormone agonist therapy on the outcome of in vitro fertilization-embryo transfer in patients with endometriosis Fertil Steril 78 2002 699 704
8. K. Zikopoulos, E.M. Kolibianakis, and P. Devroey Ovarian stimulation for in vitro fertilization in patients with endometriosis Acta Obstet Gynecol Scand 83 2004 651 655
9. R.G. Edwards Clinical approaches to increasing uterine receptivity during human implantation Hum Reprod 10 Suppl 2 1995 60 66
10. R.G. Edwards, S. Morcos, M. Macnamee, J.P. Balmaceda, D.E. Walters, and R. Asch High fecundity of amenorrhoeic women in embryo-transfer programmes Lancet 338 1991 292 294
11. C. Flamigni, and A. Borini Counselling post-menopausal women for donor in-vitro fertilization and hormone replacement therapy Hum Reprod 10 1995 1237 1241
12. F.J. Broekmans, R.E. Bernardus, G. Berkhout, and J. Schoemaker Pituitary and ovarian suppression after early follicular and mid-luteal administration of a LHRH agonist in a depot formulation: Decapeptyl CR Gynecol Endocrinol 6 1992 153 161
13. F. Fabregues, J. Balasch, M. Creus, S. Civico, F. Carmona, and B. Puerto et al. Long-term down-regulation does not improve pregnancy rates in an in vitro fertilization program Fertil Steril 70 1998 46 51
14. D. Loutradis, K. Kallianidis, G. Sakellaropoulos, J. Dokos, K. Siskos, and G. Creatsas et al. Outcome of ovarian response after suppression with a gonadotropin releasing hormone agonist in different chronological periods prior to gonadotropin stimulation for in vitro fertilization Gynecol Obstet Invest 32 1991 68 71
15. D. Loutradis, P. Drakakis, K. Kallianidis, R. Bletsa, S. Milingos, and N. Makris et al. The effect of the duration of GnRH-Agonist down regulation before ovarian stimulation on the biological and clinical outcome after intracytoplasmic sperm injection Eur J Obstet Gynecol Reprod Biol 80 1998 251 255
16. L. Dessolle, D. Ferrier, A. Colombel, T. Freour, M. Jean, and P. Barriere Prolonging GnRH-Agonist to achieve ovarian suppression does not compromise the results of a long protocol Eur J Obstet Gynecol Reprod Biol 159 2011 111 114
17. K.S. Richter, K.R. Bugge, J.G. Bromer, and M.J. Levy Relationship between endometrial thickness and embryo implantation, based on 1,294 cycles of in vitro fertilization with transfer of two blastocyst-stage embryos Fertil Steril 87 2007 53 59
18. A. Al-Ghamdi, S. Coskun, S. Al-Hassan, R. Al-Rejjal, and K. Awartani The correlation between endometrial thickness and outcome of in vitro fertilization and embryo transfer (IVF-ET) outcome Reprod Biol Endocrinol 6 2008 37
19. S.L. Chen, F.R. Wu, C. Luo, X. Chen, X.Y. Shi, and H.Y. Zheng et al. Combined analysis of endometrial thickness and pattern in predicting outcome of in vitro fertilization and embryo transfer: A retrospective cohort study Reprod Biol Endocrinol 8 2010 30
20. E.M. Casan, F. Raga, and M.L. Polan GnRH mRNA and protein expression in human preimplantation embryos Mol Hum Reprod 5 1999 234 239
21. K.N. Khan, M. Kitajima, K. Hiraki, A. Fujishita, I. Sekine, and T. Ishimaru et al. Changes in tissue inflammation, angiogenesis and apoptosis in endometriosis, adenomyosis and uterine myoma after GnRH agonist therapy Hum Reprod 25 2010 642 653
22. Y.A. Kim, M.R. Kim, J.H. Lee, J.Y. Kim, K.J. Hwang, and H.S. Kim et al. Gonadotropin-releasing hormone agonist reduces aromatase cytochrome P450 and cyclooxygenase-2 in ovarian endometrioma and eutopic endometrium of patients with endometriosis Gynecol Obstet Invest 68 2009 73 81
23. Y. Sakamoto, T. Harada, S. Horie, Y. Iba, F. Taniguchi, and S. Yoshida et al. Tumor necrosis factor-Alpha-induced interleukin-8 (IL-8) expression in endometriotic stromal cells, probably through nuclear factor-kappa B activation: gonadotropin-releasing hormone agonist treatment reduced IL-8 expression J Clin Endocrinol Metab 88 2003 730 735
24. X. Luo, J. Xu, and N. Chegini Gonadotropin releasing hormone analogue (GnRH-A) alters the expression and activation of Smad in human endometrial epithelial and stromal cells Reprod Biol Endocrinol 1 2003 125
25. G.F. Meresman, M.A. Bilotas, E. Lombardi, M. Tesone, C. Sueldo, and R.I. Baranao Effect of GnRH analogues on apoptosis and release of interleukin-1beta and vascular endothelial growth factor in endometrial cell cultures from patients with endometriosis Hum Reprod 18 2003 1767 1771
26. H.C. Ruan, X.M. Zhu, Q. Luo, A.X. Liu, Y.L. Qian, and C.Y. Zhou et al. Ovarian stimulation with GnRH agonist, but not GnRH antagonist, partially restores the expression of endometrial integrin β3 and leukaemia-inhibitory factor and improves uterine receptivity in mice Hum Reprod 21 2006 2521 2529
27. M. Schachter, S. Friedler, R. Ron-El, A.L. Zimmerman, D. Strassburger, and O. Bern et al. Can pregnancy rate be improved in gonadotropin-releasing hormone (GnRH) antagonist cycles by administering GnRH agonist before oocyte retrieval? A prospective, randomized study Fertil Steril 90 2008 1087 1093
28. J. Tesarik, A. Hazout, and C. Mendoza Enhancement of embryo developmental potential by a single administration of GnRH agonist at the time of implantation Hum Reprod 19 2004 1176 1180
29. J. Tesarik, A. Hazout, R. Mendoza-Tesarik, N. Mendoza, and C. Mendoza Beneficial effect of luteal-phase GnRH agonist administration on embryo implantation after ICSI in both GnRH agonist-And antagonist-treated ovarian stimulation cycles Hum Reprod 21 2006 2572 2579
30. M. Bahceci, U. Ulug, H.F. Erden, S. Tosun, and N. Ciray Frozen-thawed cleavage-stage embryo transfer cycles after previous GnRH agonist or antagonist stimulation Reprod Biomed Online 18 2009 67 72
31. J.R. Lee, Y.S. Choi, B.C. Jee, S.Y. Ku, C.S. Suh, and K.C. Kim et al. Cryopreserved blastocyst transfer: impact of gonadotropin-releasing hormone agonist versus antagonist in the previous oocyte retrieval cycles Fertil Steril 88 2007 1344 1349
32. T. Eldar-Geva, E. Zylber-Haran, R. Babayof, T. Halevy-Shalem, A. Ben-Chetrit, and A. Tsafrir et al. Similar outcome for cryopreserved embryo transfer following GnRH-Antagonist/GnRH-Agonist, GnRH-Antagonist/HCG or long protocol ovarian stimulation Reprod Biomed Online 14 2007 148 154
33. R. Medved, I. Virant-Klun, H. Meden-Vrtovec, and T. Tomazevic Outcome of frozen-thawed blastocysts derived from gonadotropin releasing hormone agonist or antagonist cycles J Assist Reprod Genet 23 2006 275 279
34. M.J. Hill, K.A. Miller, and J.L. Frattarelli A GnRH agonist and exogenous hormone stimulation protocol has a higher live-birth rate than a natural endogenous hormone protocol for frozen-thawed blastocyst-stage embryo transfer cycles: An analysis of 1391 cycles Fertil Steril 93 2010 416 422
35. T. El-Toukhy, A. Taylor, Y. Khalaf, K. Al-Darazi, P. Rowell, and P. Seed et al. Pituitary suppression in ultrasound-monitored frozen embryo replacement cycles: A randomised study Hum Reprod 19 2004 874 879
36. E.R. Groenewoud, A.E. Cantineau, B.J. Kollen, N.S. Macklon, and B.J. Cohlen What is the optimal means of preparing the endometrium in frozen-thawed embryo transfer cycles? A systematic review and meta-Analysis Hum Reprod Update 19 2013 458 470
37. L. Dal Prato, A. Borini, G. Coticchio, M. Cattoli, and C. Flamigni Half-dose depot triptorelin in pituitary suppression for multiple ovarian stimulation in assisted reproduction technology: A randomized study Hum Reprod 19 2004 2200 2205
38. Y. Li, D. Yang, and Q. Zhang Clinical outcome of one-third-dose depot triptorelin is the same as half-dose depot triptorelin in the long protocol of controlled ovarian stimulation J Hum Reprod Sci 5 2012 14 19
39. J. Tesarik, A. Hazout, and C. Mendoza Luteinizing hormone affects uterine receptivity independently of ovarian function Reprod Biomed Online 7 2003 59 64
40. R. Fleming, F. Lloyd, M. Herbert, J. Fenwick, T. Griffiths, and A. Murdoch Effects of profound suppression of luteinizing hormone during ovarian stimulation on follicular activity, oocyte and embryo function in cycles stimulated with purified follicle stimulating hormone Hum Reprod 13 1998 1788 1792
41. P. Humaidan, L. Bungum, M. Bungum, and C.Y. Andersen Ovarian response and pregnancy outcome related to mid-follicular LH levels in women undergoing assisted reproduction with GnRH agonist down-regulation and recombinant FSH stimulation Hum Reprod 17 2002 2016 2021
42. L.G. Westergaard, S.B. Laursen, and C.Y. Andersen Increased risk of early pregnancy loss by profound suppression of luteinizing hormone during ovarian stimulation in normogonadotrophic women undergoing assisted reproduction Hum Reprod 15 2000 1003 1008
43. S.F. Yim, I.H. Lok, L.P. Cheung, C.M. Briton-Jones, T.T. Chiu, and C.J. Haines Dose-finding study for the use of long-Acting gonadotropin-releasing hormone analogues prior to ovarian stimulation for IVF Hum Reprod 16 2001 492 494
44. W.R. Shadish, M. Clark, and P.M. Steiner Can nonrandomized experiments yield accurate answers? A randomized experiment comparing random and nonrandom assignments J Am Stat Assoc 103 2008 1334 1344