Age-associated changes of cerebrospinal fluid amyloid-β and tau incynomolgus monkeys

Neurobiology of Aging

Volumn 35, Issue 7, 2014, Pages 1656-1659

  Yue, Feng ^a,b   Lu, Chunling ^c   Ai, Yi ^d   Chan, Piu ^a,b   Zhang, Zhiming ^d  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^c Guangxi Nanning Wincon TheraCells Biotechnologies Co   (China)

^d UNIVERSITY OF KENTUCKY   (United States)

Author keywords

amyloid; Age; CSF; Cynomolgus monkey; P Tau

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; TAU PROTEIN;

ADOLESCENT; ADULT; AGED; AGING; ANIMAL EXPERIMENT; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; MACACA FASCICULARIS; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CEREBROSPINAL FLUID LEVEL; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS;

AGE; CSF; CYNOMOLGUS MONKEY; P-TAU; Β-AMYLOID;

AGING; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; BIOLOGICAL MARKERS; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; MACACA FASCICULARIS; MALE; NEURODEGENERATIVE DISEASES; PEPTIDE FRAGMENTS; PHOSPHORYLATION; TAU PROTEINS;

EID: 84903365536     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2014.01.139     Document Type: Article

References (21)

1. Brys M., Pirraglia E., Rich K., Rolstad S., Mosconi L., Switalski R., Glodzik-Sobanska L., De Santi S., Zinkowski R., Mehta P., Pratico D., Saint Louis L.A., Wallin A., Blennow K., de Leon M.J. Prediction and longitudinal study of CSF biomarkers in mild cognitive impairment. Neurobiol. Aging 2009, 30:682-690.
2. Buchhave P., Minthon L., Zetterberg H., Wallin A.K., Blennow K., Hansson O. Cerebrospinal fluid levels of beta-amyloid 1-42, but not of tau, are fully changed already 5 to 10 years before the onset of Alzheimer dementia. Arch. Gen. Psychiatry 2012, 69:98-106.
3. Darusman H.S., Sajuthi D., Kalliokoski O., Jacobsen K.R., Call J., Schapiro S.J., Gjedde A., Abelson K.S., Hau J. Correlations between serum levels of beta amyloid, cerebrospinal levels of tau and phospho tau, and delayed response tasks in young and aged cynomolgus monkeys (Macaca fascicularis). J.Med. Primatol. 2013, 42:137-146.
4. Fukumoto H., Rosene D.L., Moss M.B., Raju S., Hyman B.T., Irizarry M.C. Beta-secretase activity increases with aging in human, monkey, and mouse brain. Am. J. Pathol. 2004, 164:719-725.
5. Galasko D. CSF tau and Abeta42: logical biomarkers for Alzheimer's disease?. Neurobiol. Aging 1998, 19:117-119.
6. Heuer E., Rosen R.F., Cintron A., Walker L.C. Nonhuman primate models of Alzheimer-like cerebral proteopathy. Curr. Pharm. Des. 2012, 18:1159-1169.
7. Hulstaert F., Blennow K., Ivanoiu A., Schoonderwaldt H.C., Riemenschneider M., De Deyn P.P., Bancher C., Cras P., Wiltfang J., Mehta P.D., Iqbal K., Pottel H., Vanmechelen E., Vanderstichele H. Improved discrimination of AD patients using beta-amyloid(1-42) and tau levels in CSF. Neurology 1999, 52:1555-1562.
8. Jack C.R., Knopman D.S., Jagust W.J., Shaw L.M., Aisen P.S., Weiner M.W., Petersen R.C., Trojanowski J.Q. Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade. Lancet Neurol. 2010, 9:119-128.
9. Kimura N., Yanagisawa K., Terao K., Ono F., Sakakibara I., Ishii Y., Kyuwa S., Yoshikawa Y. Age-related changes of intracellular Abeta in cynomolgus monkey brains. Neuropathol. Appl. Neurobiol. 2005, 31:170-180.
10. Lewczuk P., Esselmann H., Otto M., Maler J.M., Henkel A.W., Henkel M.K., Eikenberg O., Antz C., Krause W.R., Reulbach U., Kornhuber J., Wiltfang J. Neurochemical diagnosis of Alzheimer's dementia by CSF Abeta42, Abeta42/Abeta40 ratio and total tau. Neurobiol. Aging 2004, 25:273-281.
11. Martin L.J., Pardo C.A., Cork L.C., Price D.L. Synaptic pathology and glial responses to neuronal injury precede the formation of senile plaques and amyloid deposits in the aging cerebral cortex. Am. J. Pathol. 1994, 145:1358-1381.
12. Martin L.J., Sisodia S.S., Koo E.H., Cork L.C., Dellovade T.L., Weidemann A., Beyreuther K., Masters C., Price D.L. Amyloid precursor protein in aged nonhuman primates. Proc. Natl. Acad. Sci. U.S.A 1991, 88:1461-1465.
13. Musiek E.S., Holtzman D.M. Origins of Alzheimer's disease: reconciling cerebrospinal fluid biomarker and neuropathology data regarding the temporal sequence of amyloid-beta and tau involvement. Curr. Opin. Neurol. 2012, 25:715-720.
14. Nakamura S., Nakayama H., Goto N., Ono F., Sakakibara I., Yoshikawa Y. Histopathological studies of senile plaques and cerebral amyloidosis in cynomolgus monkeys. J.Med. Primatol. 1998, 27:244-252.
15. Nakayama H., Uchida K., Doi K. A comparative study of age-related brain pathology-are neurodegenerative diseases present in nonhuman animals?. Med Hypoth. 2004, 632:198-202.
16. Nutu M., Zetterberg H., Londos E., Minthon L., Nagga K., Blennow K., Hansson O., Ohrfelt A. Evaluation of the cerebrospinal fluid amyloid-beta1-42/amyloid-beta1-40 ratio measured by alpha-LISA to distinguish Alzheimer's disease from other dementia disorders. Dement Geriatr. Cogn. Disord. 2013, 36:99-110.
17. Oikawa N., Kimura N., Yanagisawa K. Alzheimer-type tau pathology in advanced aged nonhuman primate brains harboring substantial amyloid deposition. Brain Res. 2010, 1315:137-149.
18. Podlisny M.B., Tolan D.R., Selkoe D.J. Homology of the amyloid beta protein precursor in monkey and human supports a primate model for beta amyloidosis in Alzheimer's disease. Am. J. Pathol. 1991, 138:1423-1435.
19. Wang L., Brier M.R., Snyder A.Z., Thomas J.B., Fagan A.M., Xiong C., Benzinger T.L., Holtzman D.M., Morris J.C., Ances B.M. Cerebrospinal fluid Abeta42, phosphorylated Tau181, and resting-state functional connectivity. JAMA Neurol. 2013, 70:1242-1248.
20. Weinbauer G.F., Niehoff M., Niehaus M., Srivastav S., Fuchs A., Van Esch E., Cline J.M. Physiology and endocrinology of the ovarian cycle in macaques. Toxicol. Pathol. 2008, 36(7S):7S-23S.
21. Wiltfang J., Esselmann H., Bibl M., Smirnov A., Otto M., Paul S., Schmidt B., Klafki H.W., Maler M., Dyrks T., Bienert M., Beyermann M., Ruther E., Kornhuber J. Highly conserved and disease-specific patterns of carboxyterminally truncated Abeta peptides 1-37/38/39 in addition to 1-40/42 in Alzheimer's disease and in patients with chronic neuroinflammation. J.Neurochem. 2002, 81:481-496.