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Volumn 40, Issue 2, 2014, Pages 287-299

Cannabis-related working memory deficits and associated subcortical morphological differences in healthy individuals and schizophrenia subjects

Author keywords

cannabis; marijuana; schizophrenia; structural neuroimaging; working memory

Indexed keywords

ALCOHOL; BIOLOGICAL MARKER; CANNABIS; CENTRAL STIMULANT AGENT; CHLORPROMAZINE; COCAINE; NEUROLEPTIC AGENT; NICOTINE; OPIATE; PSYCHEDELIC AGENT; SEDATIVE AGENT;

EID: 84903362688     PISSN: 05867614     EISSN: 17451701     Source Type: Journal    
DOI: 10.1093/schbul/sbt176     Document Type: Article
Times cited : (55)

References (70)
  • 1
    • 84856334928 scopus 로고    scopus 로고
    • Substance Abuse and Mental Health Services Administration (SAMHSA) DHHS Publication No. SMA 11-4658. Rockville, MD: Office of Applied Studies March 12, 2013
    • Substance Abuse and Mental Health Services Administration (SAMHSA). Results from the 2010 National Survey on Drug Use and Health: Summary of National Findings. DHHS Publication No. SMA 11-4658. Rockville, MD: Office of Applied Studies; 2011. http://www.oas.samhsa.gov/ NSDUH/2k5nsduh/tabs/2k5Tabs. pdf. March 12, 2013.
    • (2011) Results from the 2010 National Survey on Drug Use and Health: Summary of National Findings
  • 3
    • 84867091431 scopus 로고    scopus 로고
    • Persistent cannabis users show neuropsychological decline from childhood to midlife
    • Meier MH, Caspi A, Ambler A, et al. Persistent cannabis users show neuropsychological decline from childhood to midlife. Proc Natl Acad Sci U S A. 2012;109:E2657-E2664.
    • (2012) Proc Natl Acad Sci U S A , vol.109
    • Meier, M.H.1    Caspi, A.2    Ambler, A.3
  • 4
    • 79954549233 scopus 로고    scopus 로고
    • An evidence based review of acute and long-term effects of cannabis use on executive cognitive functions
    • Crean RD, Crane NA, Mason BJ. An evidence based review of acute and long-term effects of cannabis use on executive cognitive functions. J Addict Med. 2011;5:1-8.
    • (2011) J Addict Med , vol.5 , pp. 1-8
    • Crean, R.D.1    Crane, N.A.2    Mason, B.J.3
  • 5
    • 84859056243 scopus 로고    scopus 로고
    • Effects of δ9- tetrahydrocannabinol on human working memory function
    • Bossong MG, Jansma JM, van Hell HH, et al. Effects of δ9- tetrahydrocannabinol on human working memory function. Biol Psychiatry. 2012;71:693-699.
    • (2012) Biol Psychiatry , vol.71 , pp. 693-699
    • Bossong, M.G.1    Jansma, J.M.2    Van Hell, H.H.3
  • 6
    • 57449100592 scopus 로고    scopus 로고
    • The chronic effects of cannabis on memory in humans: A review
    • Solowij N, Battisti R. The chronic effects of cannabis on memory in humans: a review. Curr Drug Abuse Rev. 2008;1:81-98.
    • (2008) Curr Drug Abuse Rev , vol.1 , pp. 81-98
    • Solowij, N.1    Battisti, R.2
  • 7
    • 0026554483 scopus 로고
    • Working memory
    • Baddeley A. Working memory. Science. 1992;255:556-559.
    • (1992) Science , vol.255 , pp. 556-559
    • Baddeley, A.1
  • 10
    • 84866933069 scopus 로고    scopus 로고
    • Adenosine A(2A)- cannabinoid CB(1) receptor interaction: An integrative mechanism in striatal glutamatergic neurotransmission
    • Tebano MT, Martire A, Popoli P. Adenosine A(2A)- cannabinoid CB(1) receptor interaction: an integrative mechanism in striatal glutamatergic neurotransmission. Brain Res. 2012;1476:108-118.
    • (2012) Brain Res , vol.1476 , pp. 108-118
    • Tebano, M.T.1    Martire, A.2    Popoli, P.3
  • 11
    • 84855977314 scopus 로고    scopus 로고
    • Working memory and response selection: A computational account of interactions among cortico-basalganglio-thalamic loops
    • Schroll H, Vitay J, Hamker FH. Working memory and response selection: a computational account of interactions among cortico-basalganglio-thalamic loops. Neural Netw. 2012;26:59-74.
    • (2012) Neural Netw , vol.26 , pp. 59-74
    • Schroll, H.1    Vitay, J.2    Hamker, F.H.3
  • 13
    • 48749103773 scopus 로고    scopus 로고
    • Cannabinoid receptors 1 and 2 (CB1 and CB2), their distribution, ligands and functional involvement in nervous system structures - A short review
    • Svizenska I, Dubovy P, Sulcova A. Cannabinoid receptors 1 and 2 (CB1 and CB2), their distribution, ligands and functional involvement in nervous system structures - a short review. Pharmacol Biochem Behav. 2008;90:501-511.
    • (2008) Pharmacol Biochem Behav , vol.90 , pp. 501-511
    • Svizenska, I.1    Dubovy, P.2    Sulcova, A.3
  • 14
    • 84873489002 scopus 로고    scopus 로고
    • Structural and functional imaging studies in chronic cannabis users: A systematic review of adolescent and adult findings
    • Batalla A, Bhattacharyya S, Yucel M, et al. Structural and functional imaging studies in chronic cannabis users: a systematic review of adolescent and adult findings. PLoS One. 2013;8:e55821.
    • (2013) PLoS One , vol.8
    • Batalla, A.1    Bhattacharyya, S.2    Yucel, M.3
  • 15
    • 84903737100 scopus 로고    scopus 로고
    • The association between regular cannabis exposure and alterations of human brain morphology: An updated review of the literature
    • In press
    • Lorenzetti V, Solowij N, Fornito A, Lubman D, Yucel M. The association between regular cannabis exposure and alterations of human brain morphology: an updated review of the literature. Curr Pharm Des. In press.
    • Curr Pharm des
    • Lorenzetti, V.1    Solowij, N.2    Fornito, A.3    Lubman, D.4    Yucel, M.5
  • 19
    • 56049087741 scopus 로고    scopus 로고
    • Regional patterns and clinical correlates of basal ganglia morphology in non-medicated schizophrenia
    • Ballmaier M, Schlagenhauf F, Toga AW, et al. Regional patterns and clinical correlates of basal ganglia morphology in non-medicated schizophrenia. Schizophr Res. 2008;106:140-147.
    • (2008) Schizophr Res , vol.106 , pp. 140-147
    • Ballmaier, M.1    Schlagenhauf, F.2    Toga, A.W.3
  • 20
    • 2442490887 scopus 로고    scopus 로고
    • Abnormalities of thalamic volume and shape in schizophrenia
    • Csernansky JG, Schindler MK, Splinter NR, et al. Abnormalities of thalamic volume and shape in schizophrenia. Am J Psychiatry. 2004;161:896-902.
    • (2004) Am J Psychiatry , vol.161 , pp. 896-902
    • Csernansky, J.G.1    Schindler, M.K.2    Splinter, N.R.3
  • 23
    • 84857572453 scopus 로고    scopus 로고
    • The impact of cannabis use on cognitive functioning in patients with schizophrenia: A meta-Analysis of existing findings and new data in a firstepisode sample
    • Yucel M, Bora E, Lubman DI, et al. The impact of cannabis use on cognitive functioning in patients with schizophrenia: a meta-Analysis of existing findings and new data in a firstepisode sample. Schizophr Bull. 2012;38:316-330.
    • (2012) Schizophr Bull , vol.38 , pp. 316-330
    • Yucel, M.1    Bora, E.2    Lubman, D.I.3
  • 24
    • 78149462958 scopus 로고    scopus 로고
    • The environment and schizophrenia
    • van Os J, Kenis G, Rutten BP. The environment and schizophrenia. Nature. 2010;468:203-212.
    • (2010) Nature , vol.468 , pp. 203-212
    • Van Os, J.1    Kenis, G.2    Rutten, B.P.3
  • 25
    • 84883453687 scopus 로고    scopus 로고
    • Comorbid substance use disorder in schizophrenia: A selective overview of neurobiological and cognitive underpinnings
    • Thoma P, Daum I. Comorbid substance use disorder in schizophrenia: a selective overview of neurobiological and cognitive underpinnings. Psychiatry Clin Neurosci. 2013;67:367-383.
    • (2013) Psychiatry Clin Neurosci , vol.67 , pp. 367-383
    • Thoma, P.1    Daum, I.2
  • 26
    • 0035878562 scopus 로고    scopus 로고
    • A neurobiological basis for substance abuse comorbidity in schizophrenia
    • Chambers RA, Krystal JH, Self DW. A neurobiological basis for substance abuse comorbidity in schizophrenia. Biol Psychiatry. 2001;50:71-83.
    • (2001) Biol Psychiatry , vol.50 , pp. 71-83
    • Chambers, R.A.1    Krystal, J.H.2    Self, D.W.3
  • 28
    • 77649234395 scopus 로고    scopus 로고
    • Increased cortical inhibition deficits in first-episode schizophrenia with comorbid cannabis abuse
    • Wobrock T, Hasan A, Malchow B, et al. Increased cortical inhibition deficits in first-episode schizophrenia with comorbid cannabis abuse. Psychopharmacology (Berl). 2010;208:353-363.
    • (2010) Psychopharmacology (Berl) , vol.208 , pp. 353-363
    • Wobrock, T.1    Hasan, A.2    Malchow, B.3
  • 29
    • 84874853045 scopus 로고    scopus 로고
    • Effects of psychoactive substances in schizophrenia - Findings of structural and functional neuroimaging
    • Walter M, Denier N, Vogel M, Lang UE. Effects of psychoactive substances in schizophrenia - findings of structural and functional neuroimaging. Curr Top Med Chem. 2012;12:2426-2433.
    • (2012) Curr Top Med Chem , vol.12 , pp. 2426-2433
    • Walter, M.1    Denier, N.2    Vogel, M.3    Lang, U.E.4
  • 31
    • 84871933160 scopus 로고    scopus 로고
    • Alteration to hippocampal shape in cannabis users with and without schizophrenia
    • Solowij N, Walterfang M, Lubman DI, et al. Alteration to hippocampal shape in cannabis users with and without schizophrenia. Schizophr Res. 2013;143:179-184.
    • (2013) Schizophr Res , vol.143 , pp. 179-184
    • Solowij, N.1    Walterfang, M.2    Lubman, D.I.3
  • 32
    • 7044231594 scopus 로고    scopus 로고
    • Computational anatomy and neuropsychiatric disease: Probabilistic assessment of variation and statistical inference of group difference, hemispheric asymmetry, and time-dependent change
    • Csernansky JG, Wang L, Joshi SC, Ratnanather JT, Miller MI. Computational anatomy and neuropsychiatric disease: probabilistic assessment of variation and statistical inference of group difference, hemispheric asymmetry, and time-dependent change. Neuroimage. 2004;23(suppl 1):S56-S68.
    • (2004) Neuroimage , vol.23 , Issue.SUPPL. 1
    • Csernansky, J.G.1    Wang, L.2    Joshi, S.C.3    Ratnanather, J.T.4    Miller, M.I.5
  • 33
    • 8844266225 scopus 로고    scopus 로고
    • Decreased absolute amygdala volume in cocaine addicts
    • Makris N, Gasic GP, Seidman LJ, et al. Decreased absolute amygdala volume in cocaine addicts. Neuron. 2004;44:729-740.
    • (2004) Neuron , vol.44 , pp. 729-740
    • Makris, N.1    Gasic, G.P.2    Seidman, L.J.3
  • 34
    • 53249098816 scopus 로고    scopus 로고
    • Cortical thickness abnormalities in cocaine addiction-A reflection of both drug use and a pre-existing disposition to drug abuse?
    • Makris N, Gasic GP, Kennedy DN, et al. Cortical thickness abnormalities in cocaine addiction - a reflection of both drug use and a pre-existing disposition to drug abuse? Neuron. 2008;60:174-188.
    • (2008) Neuron , vol.60 , pp. 174-188
    • Makris, N.1    Gasic, G.P.2    Kennedy, D.N.3
  • 35
    • 0015021890 scopus 로고
    • The assessment and analysis of handedness: The Edinburgh inventory
    • Oldfield RC. The assessment and analysis of handedness: the Edinburgh inventory. Neuropsychologia. 1971;9:97-113.
    • (1971) Neuropsychologia , vol.9 , pp. 97-113
    • Oldfield, R.C.1
  • 38
    • 56949093709 scopus 로고    scopus 로고
    • The reliability of self-reported cannabis abuse, dependence and withdrawal symptoms: Multisite study of differences between general population and treatment groups
    • Mennes CE, Ben Abdallah A, Cottler LB. The reliability of self-reported cannabis abuse, dependence and withdrawal symptoms: multisite study of differences between general population and treatment groups. Addict Behav. 2009;34:223-226.
    • (2009) Addict Behav , vol.34 , pp. 223-226
    • Mennes, C.E.1    Ben Abdallah, A.2    Cottler, L.B.3
  • 39
    • 73549110068 scopus 로고    scopus 로고
    • Antipsychotic dose equivalents and dose-years: A standardized method for comparing exposure to different drugs
    • Andreasen NC, Pressler M, Nopoulos P, Miller D, Ho BC. Antipsychotic dose equivalents and dose-years: a standardized method for comparing exposure to different drugs. Biol Psychiatry. 2010;67:255-262.
    • (2010) Biol Psychiatry , vol.67 , pp. 255-262
    • Andreasen, N.C.1    Pressler, M.2    Nopoulos, P.3    Miller, D.4    Ho, B.C.5
  • 40
    • 56049117857 scopus 로고    scopus 로고
    • Elevated rates of substance use disorders in non-psychotic siblings of individuals with schizophrenia
    • Smith MJ, Barch DM, Wolf TJ, Mamah D, Csernansky JG. Elevated rates of substance use disorders in non-psychotic siblings of individuals with schizophrenia. Schizophr Res. 2008;106:294-299.
    • (2008) Schizophr Res , vol.106 , pp. 294-299
    • Smith, M.J.1    Barch, D.M.2    Wolf, T.J.3    Mamah, D.4    Csernansky, J.G.5
  • 42
    • 0003441705 scopus 로고    scopus 로고
    • Third Edition. San Antonio, TX: The Psychological Corporation
    • Wechsler D. Wechsler Memory Scale - Third Edition. San Antonio, TX: The Psychological Corporation; 1997.
    • (1997) Wechsler Memory Scale
    • Wechsler, D.1
  • 46
    • 0031377908 scopus 로고    scopus 로고
    • Role of high resolution in magnetic resonance (MR) imaging: Applications for MR angiography, intracranial T1-weighted imaging, and image interpolation
    • Venkatesan R, Haacke EM. Role of high resolution in magnetic resonance (MR) imaging: applications for MR angiography, intracranial T1-weighted imaging, and image interpolation. Int J Imag Syst Tech. 1997;8:529-543.
    • (1997) Int J Imag Syst Tech , vol.8 , pp. 529-543
    • Venkatesan, R.1    Haacke, E.M.2
  • 47
    • 5644271407 scopus 로고    scopus 로고
    • A unified approach for morphometric and functional data analysis in young, old, and demented adults using automated atlas-based head size normalization: Reliability and validation against manual measurement of total intracranial volume
    • Buckner RL, Head D, Parker J, et al. A unified approach for morphometric and functional data analysis in young, old, and demented adults using automated atlas-based head size normalization: reliability and validation against manual measurement of total intracranial volume. Neuroimage. 2004;23:724-738.
    • (2004) Neuroimage , vol.23 , pp. 724-738
    • Buckner, R.L.1    Head, D.2    Parker, J.3
  • 49
    • 56349157377 scopus 로고    scopus 로고
    • Progressive deformation of deep brain nuclei and hippocampal-Amygdala formation in schizophrenia
    • Wang L, Mamah D, Harms MP, et al. Progressive deformation of deep brain nuclei and hippocampal-Amygdala formation in schizophrenia. Biol Psychiatry. 2008;64:1060-1068.
    • (2008) Biol Psychiatry , vol.64 , pp. 1060-1068
    • Wang, L.1    Mamah, D.2    Harms, M.P.3
  • 50
    • 0034141486 scopus 로고    scopus 로고
    • Nicotine impairs spatial working memory while leaving spatial attention intact
    • Park S, Knopick C, McGurk S, Meltzer HY. Nicotine impairs spatial working memory while leaving spatial attention intact. Neuropsychopharmacology. 2000;22:200-209.
    • (2000) Neuropsychopharmacology , vol.22 , pp. 200-209
    • Park, S.1    Knopick, C.2    McGurk, S.3    Meltzer, H.Y.4
  • 51
    • 34548498851 scopus 로고    scopus 로고
    • Antipsychotic drugs exacerbate impairment on a working memory task in first-episode schizophrenia
    • Reilly JL, Harris MS, Khine TT, Keshavan MS, Sweeney JA. Antipsychotic drugs exacerbate impairment on a working memory task in first-episode schizophrenia. Biol Psychiatry. 2007;62:818-821.
    • (2007) Biol Psychiatry , vol.62 , pp. 818-821
    • Reilly, J.L.1    Harris, M.S.2    Khine, T.T.3    Keshavan, M.S.4    Sweeney, J.A.5
  • 52
    • 0345791446 scopus 로고    scopus 로고
    • Differences between smokers and nonsmokers in regional gray matter volumes and densities
    • Brody AL, Mandelkern MA, Jarvik ME, et al. Differences between smokers and nonsmokers in regional gray matter volumes and densities. Biol Psychiatry. 2004;55:77-84.
    • (2004) Biol Psychiatry , vol.55 , pp. 77-84
    • Brody, A.L.1    Mandelkern, M.A.2    Jarvik, M.E.3
  • 53
    • 0028938076 scopus 로고
    • Cellular basis of working memory
    • Goldman-Rakic PS. Cellular basis of working memory. Neuron. 1995;14:477-485.
    • (1995) Neuron , vol.14 , pp. 477-485
    • Goldman-Rakic, P.S.1
  • 54
    • 57349167353 scopus 로고    scopus 로고
    • Subunit-selective modulation of GABA type A receptor neurotransmission and cognition in schizophrenia
    • Lewis DA, Cho RY, Carter CS, et al. Subunit-selective modulation of GABA type A receptor neurotransmission and cognition in schizophrenia. Am J Psychiatry. 2008;165:1585-1593.
    • (2008) Am J Psychiatry , vol.165 , pp. 1585-1593
    • Lewis, D.A.1    Cho, R.Y.2    Carter, C.S.3
  • 56
    • 0020071278 scopus 로고
    • Symmetry and asymmetry in the human posterior thalamus. I. Cytoarchitectonic analysis in normal persons
    • Eidelberg D, Galaburda AM. Symmetry and asymmetry in the human posterior thalamus. I. Cytoarchitectonic analysis in normal persons. Arch Neurol. 1982;39:325-332.
    • (1982) Arch Neurol , vol.39 , pp. 325-332
    • Eidelberg, D.1    Galaburda, A.M.2
  • 57
    • 0034878099 scopus 로고    scopus 로고
    • Structural asymmetries in the human brain: A voxel-based statistical analysis of 142 MRI scans
    • Watkins KE, Paus T, Lerch JP, et al. Structural asymmetries in the human brain: a voxel-based statistical analysis of 142 MRI scans. Cereb Cortex. 2001;11:868-877.
    • (2001) Cereb Cortex , vol.11 , pp. 868-877
    • Watkins, K.E.1    Paus, T.2    Lerch, J.P.3
  • 58
    • 0033005817 scopus 로고    scopus 로고
    • Structural asymmetries of the human brain and their disturbance in schizophrenia
    • Petty RG. Structural asymmetries of the human brain and their disturbance in schizophrenia. Schizophr Bull. 1999;25:121-139.
    • (1999) Schizophr Bull , vol.25 , pp. 121-139
    • Petty, R.G.1
  • 59
    • 33846839155 scopus 로고    scopus 로고
    • Effects of alcohol and combined marijuana and alcohol use during adolescence on hippocampal volume and asymmetry
    • Medina KL, Schweinsburg AD, Cohen-Zion M, Nagel BJ, Tapert SF. Effects of alcohol and combined marijuana and alcohol use during adolescence on hippocampal volume and asymmetry. Neurotoxicol Teratol. 2007;29:141-152.
    • (2007) Neurotoxicol Teratol , vol.29 , pp. 141-152
    • Medina, K.L.1    Schweinsburg, A.D.2    Cohen-Zion, M.3    Nagel, B.J.4    Tapert, S.F.5
  • 60
    • 37249055926 scopus 로고    scopus 로고
    • Thalamic shape abnormalities in individuals with schizophrenia and their nonpsychotic siblings
    • Harms MP, Wang L, Mamah D, Barch DM, Thompson PA, Csernansky JG. Thalamic shape abnormalities in individuals with schizophrenia and their nonpsychotic siblings. J Neurosci. 2007;27:13835-13842.
    • (2007) J Neurosci , vol.27 , pp. 13835-13842
    • Harms, M.P.1    Wang, L.2    Mamah, D.3    Barch, D.M.4    Thompson, P.A.5    Csernansky, J.G.6
  • 61
    • 45449097426 scopus 로고    scopus 로고
    • Basal ganglia shape abnormalities in the unaffected siblings of schizophrenia patients
    • Mamah D, Harms MP, Wang L, et al. Basal ganglia shape abnormalities in the unaffected siblings of schizophrenia patients. Biol Psychiatry. 2008;64:111-120.
    • (2008) Biol Psychiatry , vol.64 , pp. 111-120
    • Mamah, D.1    Harms, M.P.2    Wang, L.3
  • 62
    • 67651045899 scopus 로고    scopus 로고
    • Combined analyses of thalamic volume, shape and white matter integrity in first-episode schizophrenia
    • Qiu A, Zhong J, Graham S, Chia MY, Sim K. Combined analyses of thalamic volume, shape and white matter integrity in first-episode schizophrenia. Neuroimage. 2009;47:1163-1171.
    • (2009) Neuroimage , vol.47 , pp. 1163-1171
    • Qiu, A.1    Zhong, J.2    Graham, S.3    Chia, M.Y.4    Sim, K.5
  • 63
    • 63849244736 scopus 로고    scopus 로고
    • Volumetric and shape analysis of the thalamus in first-episode schizophrenia
    • Coscia DM, Narr KL, Robinson DG, et al. Volumetric and shape analysis of the thalamus in first-episode schizophrenia. Hum Brain Mapp. 2009;30:1236-1245.
    • (2009) Hum Brain Mapp , vol.30 , pp. 1236-1245
    • Coscia, D.M.1    Narr, K.L.2    Robinson, D.G.3
  • 64
    • 80655148022 scopus 로고    scopus 로고
    • Impact of cannabis use on thalamic volume in people at familial high risk of schizophrenia
    • Welch KA, Stanfield AC, McIntosh AM, et al. Impact of cannabis use on thalamic volume in people at familial high risk of schizophrenia. Br J Psychiatry. 2011;199:386-390.
    • (2011) Br J Psychiatry , vol.199 , pp. 386-390
    • Welch, K.A.1    Stanfield, A.C.2    McIntosh, A.M.3
  • 65
    • 84884134861 scopus 로고    scopus 로고
    • Cannabis users have higher premorbid IQ than other patients with first onset psychosis
    • Ferraro L, Russo M, O'Connor J, et al. Cannabis users have higher premorbid IQ than other patients with first onset psychosis. Schizophr Res. 2013;150:129-135.
    • (2013) Schizophr Res , vol.150 , pp. 129-135
    • Ferraro, L.1    Russo, M.2    O'Connor, J.3
  • 66
    • 77955992306 scopus 로고    scopus 로고
    • Adolescent brain maturation, the endogenous cannabinoid system and the neurobiology of cannabis-induced schizophrenia
    • Bossong MG, Niesink RJ. Adolescent brain maturation, the endogenous cannabinoid system and the neurobiology of cannabis-induced schizophrenia. Prog Neurobiol. 2010;92:370-385.
    • (2010) Prog Neurobiol , vol.92 , pp. 370-385
    • Bossong, M.G.1    Niesink, R.J.2
  • 67
    • 3242789385 scopus 로고    scopus 로고
    • The psychotomimetic effects of intravenous delta-9-tetrahydrocannabinol in healthy individuals: Implications for psychosis
    • D'Souza DC, Perry E, MacDougall L, et al. The psychotomimetic effects of intravenous delta-9-tetrahydrocannabinol in healthy individuals: implications for psychosis. Neuropsychopharmacology. 2004;29:1558-1572.
    • (2004) Neuropsychopharmacology , vol.29 , pp. 1558-1572
    • D'Souza, D.C.1    Perry, E.2    Macdougall, L.3
  • 68
    • 33748612195 scopus 로고    scopus 로고
    • Chronic treatment with delta-9-tetrahydrocannabinol alters the structure of neurons in the nucleus accumbens shell and medial prefrontal cortex of rats
    • Kolb B, Gorny G, Limebeer CL, Parker LA. Chronic treatment with delta-9-tetrahydrocannabinol alters the structure of neurons in the nucleus accumbens shell and medial prefrontal cortex of rats. Synapse. 2006;60:429-436.
    • (2006) Synapse , vol.60 , pp. 429-436
    • Kolb, B.1    Gorny, G.2    Limebeer, C.L.3    Parker, L.A.4
  • 69
    • 79955473476 scopus 로고    scopus 로고
    • Greater white and grey matter changes associated with early cannabis use in adolescent-onset schizophrenia (AOS)
    • James A, Hough M, James S, et al. Greater white and grey matter changes associated with early cannabis use in adolescent-onset schizophrenia (AOS). Schizophr Res. 2011;128:91-97.
    • (2011) Schizophr Res , vol.128 , pp. 91-97
    • James, A.1    Hough, M.2    James, S.3
  • 70
    • 77952170829 scopus 로고    scopus 로고
    • Cannabinoiddopamine interaction in the pathophysiology and treatment of CNS disorders
    • Fernandez-Ruiz J, Hernandez M, Ramos JA. Cannabinoiddopamine interaction in the pathophysiology and treatment of CNS disorders. CNS Neurosci Ther. 2010;16:e72-e91.
    • (2010) CNS Neurosci Ther , vol.16
    • Fernandez-Ruiz, J.1    Hernandez, M.2    Ramos, J.A.3


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