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Volumn 19, Issue 6, 2014, Pages 7287-7307

Synthesis and evaluation of a series of novel asymmetrical curcumin analogs for the treatment of inflammation

Author keywords

Anti inflammation; Asymmetrical curcumin analogs; Curcumin; Cytokines; QSAR

Indexed keywords

ANTIINFLAMMATORY AGENT; CURCUMIN; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR ALPHA;

EID: 84903318555     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules19067287     Document Type: Article
Times cited : (26)

References (31)
  • 4
    • 84878681421 scopus 로고    scopus 로고
    • Therapeutic potential of curcumin in experimentally induced allergic rhinitis in guinea pigs
    • Thakare, V.N.; Osama, M.M.; Naik, S.R. Therapeutic potential of curcumin in experimentally induced allergic rhinitis in guinea pigs. Int. Immunopharmacol. 2013, 17, 18-25.
    • (2013) Int. Immunopharmacol. , vol.17 , pp. 18-25
    • Thakare, V.N.1    Osama, M.M.2    Naik, S.R.3
  • 5
    • 84879886056 scopus 로고    scopus 로고
    • Curcumin protects against collagen-induced arthritis via suppression of BAFF production
    • Huang, G.; Xu, Z.; Huang, Y.; Duan, X.; Gong, W.; Zhang, Y.; Fan, J.; He, F. Curcumin protects against collagen-induced arthritis via suppression of BAFF production. J. Clin. Immunol. 2013, 33, 550-557.
    • (2013) J. Clin. Immunol. , vol.33 , pp. 550-557
    • Huang, G.1    Xu, Z.2    Huang, Y.3    Duan, X.4    Gong, W.5    Zhang, Y.6    Fan, J.7    He, F.8
  • 8
    • 0032926620 scopus 로고    scopus 로고
    • Biotransformation of curcumin through reduction and glucuronidation in micse
    • Pan, M.H.; Huang, T.M.; Lin, J.K. Biotransformation of curcumin through reduction and glucuronidation in micse. Drug Metab. Dispos. 1999, 27, 486-494.
    • (1999) Drug Metab. Dispos. , vol.27 , pp. 486-494
    • Pan, M.H.1    Huang, T.M.2    Lin, J.K.3
  • 12
    • 0034492793 scopus 로고    scopus 로고
    • Recent studies on the biofunctions and biotransformations of curcumin
    • Lin, J.K.; Pan, M.H.; Lin-Shiau, S.Y. Recent studies on the biofunctions and biotransformations of curcumin. BioFactors 2000, 13, 153-158.
    • (2000) BioFactors , vol.13 , pp. 153-158
    • Lin, J.K.1    Pan, M.H.2    Lin-Shiau, S.Y.3
  • 13
  • 14
    • 1542286600 scopus 로고    scopus 로고
    • Enzymology of a carbonyl reduction clearance pathway for the HIV integrase inhibitor S-1360 : Role of human liver cytosolic aldo-keto reductases
    • Rosemond, M.J.; St. John-Williams, L.; Yamaguchi, T.; Fujishita, T.; Walsh, J.S. Enzymology of a carbonyl reduction clearance pathway for the HIV integrase inhibitor, S-1360 : Role of human liver cytosolic aldo-keto reductases. Chem.-Biol. Interact. 2004, 147, 129-139.
    • (2004) Chem.-Biol. Interact. , vol.147 , pp. 129-139
    • Rosemond, M.J.1    John-Williams St., L.2    Yamaguchi, T.3    Fujishita, T.4    Walsh, J.S.5
  • 15
    • 21744450137 scopus 로고    scopus 로고
    • Emergent mechanistic diversity of enzyme-catalysed beta-diketone cleavage
    • Grogan, G. Emergent mechanistic diversity of enzyme-catalysed beta-diketone cleavage. Biochem. J. 2005, 388, 721-730.
    • (2005) Biochem. J. , vol.388 , pp. 721-730
    • Grogan, G.1
  • 16
    • 62149086696 scopus 로고    scopus 로고
    • Exploration and synthesis of curcumin analogues with improved structural stabi lity both in vitro and in vivo as cytotoxic agents
    • Liang, G.; Shao, L.; Wang, Y.; Zhao, C.; Chu, Y.; Xiao, J.; Zhao, Y.; Li, X.; Yang, S. Exploration and synthesis of curcumin analogues with improved structural stabi lity both in vitro and in vivo as cytotoxic agents. Bioorg. Med. Chem. 2009, 17, 2623-2631.
    • (2009) Bioorg. Med. Chem. , vol.17 , pp. 2623-2631
    • Liang, G.1    Shao, L.2    Wang, Y.3    Zhao, C.4    Chu, Y.5    Xiao, J.6    Zhao, Y.7    Li, X.8    Yang, S.9
  • 17
    • 77950045538 scopus 로고    scopus 로고
    • Synthesis of mono-carbonyl analogues of curcumin and their effects on inhibition of cytokine release in LPS-stimulated RAW 264.7 macrophages
    • Zhao, C.; Yang, J.; Wang, Y.; Liang, D.; Yang, X.; Li, X.; Wu, J.; Wu, X.; Yang, S.; Li, X. Synthesis of mono-carbonyl analogues of curcumin and their effects on inhibition of cytokine release in LPS-stimulated RAW 264.7 macrophages. Bioorg. Med. Chem. 2010, 18, 2388-2393.
    • (2010) Bioorg. Med. Chem. , vol.18 , pp. 2388-2393
    • Zhao, C.1    Yang, J.2    Wang, Y.3    Liang, D.4    Yang, X.5    Li, X.6    Wu, J.7    Wu, X.8    Yang, S.9    Li, X.10
  • 18
    • 84875395775 scopus 로고    scopus 로고
    • Promising curcumin-based drug design: Mono-carbonyl analogues of curcumin (MACs)
    • Zhao, C.; Liu, Z.; Liang, G. Promising curcumin-based drug design: Mono-carbonyl analogues of curcumin (MACs). Curr. Pharm. Des. 2013, 19, 2114-2135.
    • (2013) Curr. Pharm. Des. , vol.19 , pp. 2114-2135
    • Zhao, C.1    Liu, Z.2    Liang, G.3
  • 19
    • 0030956673 scopus 로고    scopus 로고
    • Inflammation aspirin, and the risk of cardiovascular disease in apparently healthy men
    • Ridker, P.M.; Cushman, M.; Stampfer, M.J.; Tracy, R.P.; Hennekens, C.H. Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men. N. Engl. J. Med. 1997, 336, 973-979.
    • (1997) N. Engl. J. Med. , vol.336 , pp. 973-979
    • Ridker, P.M.1    Cushman, M.2    Stampfer, M.J.3    Tracy, R.P.4    Hennekens, C.H.5
  • 20
    • 0142089894 scopus 로고    scopus 로고
    • Blockade of receptor for advanced glycation endproducts: A new target fo r therapeutic intervention in diabetic complications and inflammatory disorders
    • Hudson, B.I.; Bucciarelli, L.G.; Wendt, T.; Sakaguchi, T.; Lalla, E.; Qu, W.; Lu, Y.; Lee, L.; Stern, D.M.; Naka, Y. Blockade of receptor for advanced glycation endproducts: A new target fo r therapeutic intervention in diabetic complications and inflammatory disorders. Arch. Biochem. Biophys. 2003, 419, 80-88.
    • (2003) Arch. Biochem. Biophys. , vol.419 , pp. 80-88
    • Hudson, B.I.1    Bucciarelli, L.G.2    Wendt, T.3    Sakaguchi, T.4    Lalla, E.5    Qu, W.6    Lu, Y.7    Lee, L.8    Stern, D.M.9    Naka, Y.10
  • 21
    • 30544445602 scopus 로고    scopus 로고
    • Cytokines sing the blues: Inflammation and the pathogenesis of depression
    • Raison, C.L.; Capuron, L.; Miller, A.H. Cytokines sing the blues: Inflammation and the pathogenesis of depression. Trends Immunol. 2006, 27, 24-31.
    • (2006) Trends Immunol. , vol.27 , pp. 24-31
    • Raison, C.L.1    Capuron, L.2    Miller, A.H.3
  • 22
    • 33745598838 scopus 로고    scopus 로고
    • The antioxidants curcumin and quercetin inhibit inflammatory processes associated with arthritis
    • Jackson, J.; Higo, T.; Hunter, W.; Burt, H. The antioxidants curcumin and quercetin inhibit inflammatory processes associated with arthritis. Inflamm. Res. 2006, 55, 168-175.
    • (2006) Inflamm. Res. , vol.55 , pp. 168-175
    • Jackson, J.1    Higo, T.2    Hunter, W.3    Burt, H.4
  • 23
    • 30744435048 scopus 로고    scopus 로고
    • Curcumin an atoxic antioxidant and natural NFkappaB, cyclooxygenase-2, lipooxygenase, and inducible nitric oxide synthase inhibitor: A shie ld against acute and chronic diseases
    • Bengmark, S. Curcumin, an atoxic antioxidant and natural NFkappaB, cyclooxygenase-2, lipooxygenase, and inducible nitric oxide synthase inhibitor: A shie ld against acute and chronic diseases. J. Parenter. Enter. Nutr. 2006, 30, 45-51.
    • (2006) J. Parenter. Enter. Nutr. , vol.30 , pp. 45-51
    • Bengmark, S.1
  • 24
    • 33947489293 scopus 로고
    • A new method for the alkylation of ketones and aldehydes: The c-alkylation of the magnesium salts of n-substituted imines
    • Stork, G.; Dowd, S.R. A New Method for the Alkylation of Ketones and Aldehydes: The C-Alkylation of the Magnesium Salts of N-Substituted Imines. J. Am. Chem. Soc. 1963, 85, 2178-2180.
    • (1963) J. Am. Chem. Soc. , vol.85 , pp. 2178-2180
    • Stork, G.1    Dowd, S.R.2
  • 25
    • 84859743787 scopus 로고    scopus 로고
    • Curcumin suppresses the production of interleukin-6 in Prevotella intermedia lipopolysaccharide-activated RAW 264.7 cells
    • Kim, S.J. Curcumin suppresses the production of interleukin-6 in Prevotella intermedia lipopolysaccharide-activated RAW 264.7 cells. J. Periodontal Implant Sci. 2011, 41, 157-163.
    • (2011) J. Periodontal Implant Sci. , vol.41 , pp. 157-163
    • Kim, S.J.1
  • 26
    • 33748702895 scopus 로고    scopus 로고
    • Classification of a diverse set of Tetrahymena pyriformis toxicity chemical compounds from molecular d escriptors by statistical learning methods
    • Xue, Y.; Li, H.; Ung, C.Y.; Yap, C.W.; Chen, Y.Z. Classification of a diverse set of Tetrahymena pyriformis toxicity chemical compounds from molecular d escriptors by statistical learning methods. Chem. Res. Toxicol. 2006, 19, 1030-1039.
    • (2006) Chem. Res. Toxicol. , vol.19 , pp. 1030-1039
    • Xue, Y.1    Li, H.2    Ung, C.Y.3    Yap, C.W.4    Chen, Y.Z.5
  • 27
    • 0036579629 scopus 로고    scopus 로고
    • Effect of curcuminoids as anti-inflammatory agents on the hepatic microvascular response to endotoxin
    • Lukita-Atmadja, W.; Ito, Y.; Baker, G.L.; McCuskey, R.S. Effect of curcuminoids as anti-inflammatory agents on the hepatic microvascular response to endotoxin. Shock 2002, 17, 399-403.
    • (2002) Shock , vol.17 , pp. 399-403
    • Lukita-Atmadja, W.1    Ito, Y.2    Baker, G.L.3    McCuskey, R.S.4
  • 28
    • 33746931581 scopus 로고    scopus 로고
    • On outliers and activity cliffs-Why QSAR often disappoints
    • Maggiora, G.M. On outliers and activity cliffs-Why QSAR often disappoints. J. Chem. Inf. Model. 2006, 46, 1535-1535.
    • (2006) J. Chem. Inf. Model. , vol.46 , pp. 1535-1535
    • Maggiora, G.M.1
  • 29
    • 35448937584 scopus 로고    scopus 로고
    • Optimization of parameters for semiempirical methods V: Modification of NDDO approximations and application to 70 elements
    • Stewart, J.J. Optimization of parameters for semiempirical methods V: Modification of NDDO approximations and application to 70 elements. J. Mol. Model. 2007, 13, 1173-1213.
    • (2007) J. Mol. Model. , vol.13 , pp. 1173-1213
    • Stewart, J.J.1
  • 30
    • 34249847812 scopus 로고    scopus 로고
    • MODEL-molecular descriptor lab: A web-based server for computing structural and physicochemical features of compounds
    • Li, Z.R.; Han, L.Y.; Xue, Y.; Yap, C.W.; Li, H.; Jiang, L.; Chen, Y.Z. MODEL-molecular descriptor lab: A web-based server for computing structural and physicochemical features of compounds. Biotechnol. Bioeng. 2007, 97, 389-396.
    • (2007) Biotechnol. Bioeng. , vol.97 , pp. 389-396
    • Li, Z.R.1    Han, L.Y.2    Xue, Y.3    Yap, C.W.4    Li, H.5    Jiang, L.6    Chen, Y.Z.7
  • 31
    • 46849107708 scopus 로고    scopus 로고
    • Nowcasting and forecasting concentrations of biological contaminants at beaches: A feasibility and case study
    • Frick, W.E.; Ge, Z.; Zepp, R.G. Nowcasting and forecasting concentrations of biological contaminants at beaches: A feasibility and case study. Environ. Sci. Technol. 2008, 42, 4818-4824 .
    • (2008) Environ. Sci. Technol. , vol.42 , pp. 4818-4824
    • Frick, W.E.1    Ge, Z.2    Zepp, R.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.