Losartan attenuates renal interstitial fibrosis and tubular cell apoptosis in a rat model of obstructive nephropathy

Molecular Medicine Reports

Volumn 10, Issue 2, 2014, Pages 638-644

  He, Ping ^a   Li, Detian ^a   Zhang, Beiru ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Losartan; Renal interstitial fibrosis; Signal transducer and activator of transcription 3; Unilateral ureteral obstruction

Indexed keywords

DIMETHYL SULFOXIDE; LOSARTAN; PROTEIN BAX; PROTEIN BCL 2; STAT3 PROTEIN; ACTIN; COLLAGEN TYPE 1; SMOOTH MUSCLE ACTIN, RAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; IMMUNOBLOTTING; KIDNEY DISEASE; KIDNEY FIBROSIS; KIDNEY TUBULE CELL; MALE; MYOFIBROBLAST; NICK END LABELING; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; RENAL INTERSTITIAL FIBROSIS; URETER LIGATION; URETER OBSTRUCTION; WESTERN BLOTTING; ANIMAL; CYTOLOGY; DISEASE COURSE; DISEASE MODEL; DRUG EFFECTS; FIBROSIS; KIDNEY TUBULE; METABOLISM; PATHOLOGY; PHOSPHORYLATION; SPRAGUE DAWLEY RAT;

ACTINS; ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; COLLAGEN TYPE I; DIMETHYL SULFOXIDE; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; FIBROSIS; KIDNEY TUBULES; LOSARTAN; MALE; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, SPRAGUE-DAWLEY; STAT3 TRANSCRIPTION FACTOR; URETERAL OBSTRUCTION;

EID: 84903301671     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2014.2304     Document Type: Article

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