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Volumn 9, Issue 6, 2014, Pages

The serine-threonine protein kinase PAK4 is dispensable in zebrafish: Identification of a morpholino-generated pseudophenotype

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; MORPHOLINO OLIGONUCLEOTIDE; NUCLEASE; P21 ACTIVATED KINASE 4; TRANSCRIPTION ACTIVATOR LIKE EFFECTOR NUCLEASE; UNCLASSIFIED DRUG; ENDONUCLEASE; P21 ACTIVATED KINASE; PAK4 PROTEIN, ZEBRAFISH; RNA; TRANSACTIVATOR PROTEIN; ZEBRAFISH PROTEIN;

EID: 84903291853     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0100268     Document Type: Article
Times cited : (40)

References (36)
  • 1
    • 12644303221 scopus 로고    scopus 로고
    • The identification of genes with unique and essential functions in the development of the zebrafish, Danio rerio
    • Haffter P, Granato M, Brand M, Mullins MC, Hammerschmidt M, et al. (1996) The identification of genes with unique and essential functions in the development of the zebrafish, Danio rerio. Development 123: 1-36.
    • (1996) Development , vol.123 , pp. 1-36
    • Haffter, P.1    Granato, M.2    Brand, M.3    Mullins, M.C.4    Hammerschmidt, M.5
  • 3
    • 84864307103 scopus 로고    scopus 로고
    • Dorsal activity of maternal squint is mediated by a non-coding function of the RNA
    • Lim S, Kumari P, Gilligan P, Quach HN, Mathavan S, et al. (2012) Dorsal activity of maternal squint is mediated by a non-coding function of the RNA. Development 139: 2903-2915.
    • (2012) Development , vol.139 , pp. 2903-2915
    • Lim, S.1    Kumari, P.2    Gilligan, P.3    Quach, H.N.4    Mathavan, S.5
  • 4
    • 0034897373 scopus 로고    scopus 로고
    • Morphant technology in model developmental systems
    • Ekker SC, Larson JD (2001) Morphant technology in model developmental systems. Genesis 30: 89-93.
    • (2001) Genesis , vol.30 , pp. 89-93
    • Ekker, S.C.1    Larson, J.D.2
  • 5
    • 49949086671 scopus 로고    scopus 로고
    • Controlling morpholino experiments: Don't stop making antisense
    • Eisen JS, Smith JC (2008) Controlling morpholino experiments: don't stop making antisense. Development 135: 1735-1743.
    • (2008) Development , vol.135 , pp. 1735-1743
    • Eisen, J.S.1    Smith, J.C.2
  • 7
    • 79151470966 scopus 로고    scopus 로고
    • Morpholino artifacts provide pitfalls and reveal a novel role for pro-apoptotic genes in hindbrain boundary development
    • Gerety SS, Wilkinson DG (2011) Morpholino artifacts provide pitfalls and reveal a novel role for pro-apoptotic genes in hindbrain boundary development. Dev Biol 350: 279-289.
    • (2011) Dev Biol , vol.350 , pp. 279-289
    • Gerety, S.S.1    Wilkinson, D.G.2
  • 8
    • 84873525879 scopus 로고    scopus 로고
    • Maternal pak4 expression is required for primitive myelopoiesis in zebrafish
    • Law SH, Sargent TD (2013) Maternal pak4 expression is required for primitive myelopoiesis in zebrafish. Mech Dev 130: 181-194.
    • (2013) Mech Dev , vol.130 , pp. 181-194
    • Law, S.H.1    Sargent, T.D.2
  • 10
    • 0032538973 scopus 로고    scopus 로고
    • PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodia
    • Abo A, Qu J, Cammarano MS, Dan C, Fritsch A, et al. (1998) PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodia. EMBO J 17: 6527-6540.
    • (1998) EMBO J , vol.17 , pp. 6527-6540
    • Abo, A.1    Qu, J.2    Cammarano, M.S.3    Dan, C.4    Fritsch, A.5
  • 11
    • 74349102008 scopus 로고    scopus 로고
    • The emerging importance of group II PAKs
    • Wells CM, Jones GE (2010) The emerging importance of group II PAKs. Biochem J 425: 465-473.
    • (2010) Biochem J , vol.425 , pp. 465-473
    • Wells, C.M.1    Jones, G.E.2
  • 12
    • 68449101709 scopus 로고    scopus 로고
    • Essential role for the Pak4 protein kinase in extraembryonic tissue development and vessel formation
    • Tian Y, Lei L, Cammarano M, Nekrasova T, Minden A (2009) Essential role for the Pak4 protein kinase in extraembryonic tissue development and vessel formation. Mech Dev 126: 710-720.
    • (2009) Mech Dev , vol.126 , pp. 710-720
    • Tian, Y.1    Lei, L.2    Cammarano, M.3    Nekrasova, T.4    Minden, A.5
  • 13
    • 0141819123 scopus 로고    scopus 로고
    • PAK4 kinase is essential for embryonic viability and for proper neuronal development
    • Qu J, Li X, Novitch BG, Zheng Y, Kohn M, et al. (2003) PAK4 kinase is essential for embryonic viability and for proper neuronal development. Mol Cell Biol 23: 7122-7133.
    • (2003) Mol Cell Biol , vol.23 , pp. 7122-7133
    • Qu, J.1    Li, X.2    Novitch, B.G.3    Zheng, Y.4    Kohn, M.5
  • 15
    • 38149126474 scopus 로고    scopus 로고
    • High-resolution in situ hybridization to whole-mount zebrafish embryos
    • Thisse C, Thisse B (2008) High-resolution in situ hybridization to whole-mount zebrafish embryos. Nat Protoc 3: 59-69.
    • (2008) Nat Protoc , vol.3 , pp. 59-69
    • Thisse, C.1    Thisse, B.2
  • 16
    • 0022497719 scopus 로고
    • Cell interactions and the control of gene activity during early development of Xenopus laevis
    • Sargent TD, Jamrich M, Dawid IB (1986) Cell interactions and the control of gene activity during early development of Xenopus laevis. Dev Biol 114: 238-246.
    • (1986) Dev Biol , vol.114 , pp. 238-246
    • Sargent, T.D.1    Jamrich, M.2    Dawid, I.B.3
  • 17
    • 0022552131 scopus 로고
    • Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes
    • Kozak M (1986) Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes. Cell 44: 283-292.
    • (1986) Cell , vol.44 , pp. 283-292
    • Kozak, M.1
  • 18
    • 0031311669 scopus 로고    scopus 로고
    • Heat shock genes and the heat shock response in zebrafish embryos
    • Krone PH, Lele Z, Sass JB (1997) Heat shock genes and the heat shock response in zebrafish embryos. Biochem Cell Biol 75: 487-497.
    • (1997) Biochem Cell Biol , vol.75 , pp. 487-497
    • Krone, P.H.1    Lele, Z.2    Sass, J.B.3
  • 19
    • 33749382352 scopus 로고    scopus 로고
    • Endo16 is required for gastrulation in the sea urchin Lytechinus variegatus
    • Romano LA, Wray GA (2006) Endo16 is required for gastrulation in the sea urchin Lytechinus variegatus. Dev Growth Differ 48: 487-497.
    • (2006) Dev Growth Differ , vol.48 , pp. 487-497
    • Romano, L.A.1    Wray, G.A.2
  • 20
    • 84868119538 scopus 로고    scopus 로고
    • Opposing nodal and BMP signals regulate left-right asymmetry in the sea urchin larva
    • Luo YJ, Su YH (2012) Opposing nodal and BMP signals regulate left-right asymmetry in the sea urchin larva. PLoS Biol 10: e1001402.
    • (2012) PLoS Biol , vol.10
    • Luo, Y.J.1    Su, Y.H.2
  • 21
    • 0242268495 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor 2 mediates 2,3,7,8-tetrachlorodibenzo-p-dioxin developmental toxicity in zebrafish
    • Prasch AL, Teraoka H, Carney SA, Dong W, Hiraga T, et al. (2003) Aryl hydrocarbon receptor 2 mediates 2,3,7,8-tetrachlorodibenzo-p-dioxin developmental toxicity in zebrafish. Toxicol Sci 76: 138-150.
    • (2003) Toxicol Sci , vol.76 , pp. 138-150
    • Prasch, A.L.1    Teraoka, H.2    Carney, S.A.3    Dong, W.4    Hiraga, T.5
  • 22
    • 20844440300 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor-mediated transcription: Ligand-dependent recruitment of estrogen receptor alpha to 2,3,7,8-tetrachlorodibenzo-p-dioxin- responsive promoters
    • Matthews J, Wihlen B, Thomsen J, Gustafsson JA (2005) Aryl hydrocarbon receptor-mediated transcription: ligand-dependent recruitment of estrogen receptor alpha to 2,3,7,8-tetrachlorodibenzo-p-dioxin-responsive promoters. Mol Cell Biol 25: 5317-5328.
    • (2005) Mol Cell Biol , vol.25 , pp. 5317-5328
    • Matthews, J.1    Wihlen, B.2    Thomsen, J.3    Gustafsson, J.A.4
  • 23
    • 84855396876 scopus 로고    scopus 로고
    • AHR2 mutant reveals functional diversity of aryl hydrocarbon receptors in zebrafish
    • Goodale BC, La Du JK, Bisson WH, Janszen DB, Waters KM, et al. (2012) AHR2 mutant reveals functional diversity of aryl hydrocarbon receptors in zebrafish. PLoS One 7: e29346.
    • (2012) PLoS One , vol.7
    • Goodale, B.C.1    La Du, J.K.2    Bisson, W.H.3    Janszen, D.B.4    Waters, K.M.5
  • 24
    • 55649119652 scopus 로고    scopus 로고
    • Analysis of WASp function during the wound inflammatory response-live-imaging studies in zebrafish larvae
    • Cvejic A, Hall C, Bak-Maier M, Flores MV, Crosier P, et al. (2008) Analysis of WASp function during the wound inflammatory response-live-imaging studies in zebrafish larvae. J Cell Sci 121: 3196-3206.
    • (2008) J Cell Sci , vol.121 , pp. 3196-3206
    • Cvejic, A.1    Hall, C.2    Bak-Maier, M.3    Flores, M.V.4    Crosier, P.5
  • 25
    • 0035876111 scopus 로고    scopus 로고
    • A crucial component of the endoderm formation pathway, CASANOVA, is encoded by a novel sox-related gene
    • Dickmeis T, Mourrain P, Saint-Etienne L, Fischer N, Aanstad P, et al. (2001) A crucial component of the endoderm formation pathway, CASANOVA, is encoded by a novel sox-related gene. Genes Dev 15: 1487-1492.
    • (2001) Genes Dev , vol.15 , pp. 1487-1492
    • Dickmeis, T.1    Mourrain, P.2    Saint-Etienne, L.3    Fischer, N.4    Aanstad, P.5
  • 26
    • 0033571308 scopus 로고    scopus 로고
    • Casanova plays an early and essential role in endoderm formation in zebrafish
    • Alexander J, Rothenberg M, Henry GL, Stainier DY (1999) casanova plays an early and essential role in endoderm formation in zebrafish. Dev Biol 215: 343-357.
    • (1999) Dev Biol , vol.215 , pp. 343-357
    • Alexander, J.1    Rothenberg, M.2    Henry, G.L.3    Stainier, D.Y.4
  • 27
    • 33751353757 scopus 로고    scopus 로고
    • Contribution of mGluR and Fmr1 functional pathways to neurite morphogenesis, craniofacial development and fragile X syndrome
    • Tucker B, Richards RI, Lardelli M (2006) Contribution of mGluR and Fmr1 functional pathways to neurite morphogenesis, craniofacial development and fragile X syndrome. Hum Mol Genet 15: 3446-3458.
    • (2006) Hum Mol Genet , vol.15 , pp. 3446-3458
    • Tucker, B.1    Richards, R.I.2    Lardelli, M.3
  • 29
    • 49049085454 scopus 로고    scopus 로고
    • barx1 is necessary for ectomesenchyme proliferation and osteochondroprogenitor condensation in the zebrafish pharyngeal arches
    • Sperber SM, Dawid IB (2008) barx1 is necessary for ectomesenchyme proliferation and osteochondroprogenitor condensation in the zebrafish pharyngeal arches. Dev Biol 321: 101-110.
    • (2008) Dev Biol , vol.321 , pp. 101-110
    • Sperber, S.M.1    Dawid, I.B.2
  • 30
    • 84878893371 scopus 로고    scopus 로고
    • barx1 represses joints and promotes cartilage in the craniofacial skeleton
    • Nichols JT, Pan L, Moens CB, Kimmel CB (2013) barx1 represses joints and promotes cartilage in the craniofacial skeleton. Development 140: 2765-2775.
    • (2013) Development , vol.140 , pp. 2765-2775
    • Nichols, J.T.1    Pan, L.2    Moens, C.B.3    Kimmel, C.B.4
  • 31
    • 34248223635 scopus 로고    scopus 로고
    • Inca: A novel p21-activated kinase-associated protein required for cranial neural crest development
    • Luo T, Xu Y, Hoffman TL, Zhang T, Schilling T, et al. (2007) Inca: a novel p21-activated kinase-associated protein required for cranial neural crest development. Development 134: 1279-1289.
    • (2007) Development , vol.134 , pp. 1279-1289
    • Luo, T.1    Xu, Y.2    Hoffman, T.L.3    Zhang, T.4    Schilling, T.5
  • 32
    • 77949851049 scopus 로고    scopus 로고
    • Generation and characterization of a novel neural crest marker allele, Inka1-LacZ, reveals a role for Inka1 in mouse neural tube closure
    • Reid BS, Sargent TD, Williams T (2010) Generation and characterization of a novel neural crest marker allele, Inka1-LacZ, reveals a role for Inka1 in mouse neural tube closure. Dev Dyn 239: 1188-1196.
    • (2010) Dev Dyn , vol.239 , pp. 1188-1196
    • Reid, B.S.1    Sargent, T.D.2    Williams, T.3
  • 33
    • 29244439927 scopus 로고    scopus 로고
    • PAK4 functions in tumor necrosis factor (TNF) alpha-induced survival pathways by facilitating TRADD binding to the TNF receptor
    • Li X, Minden A (2005) PAK4 functions in tumor necrosis factor (TNF) alpha-induced survival pathways by facilitating TRADD binding to the TNF receptor. J Biol Chem 280: 41192-41200.
    • (2005) J Biol Chem , vol.280 , pp. 41192-41200
    • Li, X.1    Minden, A.2
  • 34
    • 0142123165 scopus 로고    scopus 로고
    • Death receptor-induced activation of initiator caspase 8 is antagonized by serine/threonine kinase PAK4
    • Gnesutta N, Minden A (2003) Death receptor-induced activation of initiator caspase 8 is antagonized by serine/threonine kinase PAK4. Mol Cell Biol 23: 7838-7848.
    • (2003) Mol Cell Biol , vol.23 , pp. 7838-7848
    • Gnesutta, N.1    Minden, A.2
  • 35
    • 0035957986 scopus 로고    scopus 로고
    • The serine/threonine kinase PAK4 prevents caspase activation and protects cells from apoptosis
    • Gnesutta N, Qu J, Minden A (2001) The serine/threonine kinase PAK4 prevents caspase activation and protects cells from apoptosis. J Biol Chem 276: 14414-14419.
    • (2001) J Biol Chem , vol.276 , pp. 14414-14419
    • Gnesutta, N.1    Qu, J.2    Minden, A.3
  • 36
    • 51649119414 scopus 로고    scopus 로고
    • The pak4 protein kinase plays a key role in cell survival and tumorigenesis in athymic mice
    • Liu Y, Xiao H, Tian Y, Nekrasova T, Hao X, et al. (2008) The pak4 protein kinase plays a key role in cell survival and tumorigenesis in athymic mice. Mol Cancer Res 6: 1215-1224.
    • (2008) Mol Cancer Res , vol.6 , pp. 1215-1224
    • Liu, Y.1    Xiao, H.2    Tian, Y.3    Nekrasova, T.4    Hao, X.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.