메뉴 건너뛰기




Volumn 8, Issue 5, 2014, Pages 461-470

Tolvaptan for the treatment of liver cirrhosis oedema

Author keywords

Albumin; Ascites; Bothersome symptom; Cirrhotic patient; Hyponatraemia; Sodium; Tolvaptan

Indexed keywords

ALBUMIN; CYTOCHROME P450 3A4; FUROSEMIDE; PLACEBO; SODIUM; TOLVAPTAN; BENZAZEPINE DERIVATIVE; VASOPRESSIN RECEPTOR ANTAGONIST;

EID: 84903207850     PISSN: 17474124     EISSN: 17474132     Source Type: Journal    
DOI: 10.1586/17474124.2014.903797     Document Type: Article
Times cited : (26)

References (40)
  • 1
    • 28844490547 scopus 로고    scopus 로고
    • Natural history and prognostic indicators of survival in cirrhosis: A systematic review of 118 studies
    • D'Amico G, GarciaYTsao G, Pagliaro L. Natural history and prognostic indicators of survival in cirrhosis: A systematic review of 118 studies. J Hepatol 2006;44(1):217Y31
    • (2006) J Hepatol , vol.44 , Issue.1 , pp. 217-231
    • D'Amico, G.1    Garcia, Y.2    Tsao, G.3    Pagliaro, L.4
  • 2
    • 33750821403 scopus 로고    scopus 로고
    • Natural history of patients hospitalized for management of cirrhotic ascites
    • Planas R, Montoliu S, Ballesté B, et al. Natural history of patients hospitalized for management of cirrhotic ascites. Clin Gastroenterol Hepatol 2006;4(11):1385Y94
    • (2006) Clin Gastroenterol Hepatol , vol.4 , Issue.11 , pp. 385-394
    • Planas, R.1    Montoliu, S.2    Ballesté, B.3
  • 3
    • 51349142798 scopus 로고    scopus 로고
    • Hyponatremia in cirrhosis: Pathogenesis, clinical significance, and management
    • Ginès P, Guevara M. Hyponatremia in cirrhosis: Pathogenesis, clinical significance, and management. Hepatology 2008;48(3): 1002Y10
    • (2008) Hepatology , vol.48 , Issue.3 , pp. 1002-1010
    • Ginès, P.1    Guevara, M.2
  • 4
    • 50949127481 scopus 로고    scopus 로고
    • Hyponatremia and mortality among patients on the liverYtransplant waiting list
    • Kim WR, Biggins SW, Kremers WK, et al. Hyponatremia and mortality among patients on the liverYtransplant waiting list. N Engl J Med 2008;359(10):1018Y26
    • (2008) N Engl J Med , vol.359 , Issue.10 , pp. 018-026
    • Kim, W.R.1    Biggins, S.W.2    Kremers, W.K.3
  • 5
    • 0345299824 scopus 로고    scopus 로고
    • Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis
    • Mazzaferro V, Regalia E, Doci R, et al. Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis. N Engl J Med 1996;334(11): 693Y9
    • (1996) N Engl J Med , vol.334 , Issue.11 , pp. 693-699
    • Mazzaferro, V.1    Regalia, E.2    Doci, R.3
  • 6
    • 84880942244 scopus 로고    scopus 로고
    • HealthYrelated quality of life and survival in Chinese patients with chronic liver disease
    • Gao F, Gao R, Li G, et al. HealthYrelated quality of life and survival in Chinese patients with chronic liver disease. Health Qual Life Outcomes 2013;11(1):131
    • (2013) Health Qual Life Outcomes , vol.11 , Issue.1 , pp. 131
    • Gao, F.1    Gao, R.2    Li, G.3
  • 8
    • 47149112187 scopus 로고    scopus 로고
    • Effects of satavaptan, a selective vasopressin V2 receptor antagonist, on ascites and serum sodium in cirrhosis with hyponatremia: A randomized trial
    • Gines P, Wong F, Watson H, et al. Effects of satavaptan, a selective vasopressin V2 receptor antagonist, on ascites and serum sodium in cirrhosis with hyponatremia: A randomized trial. Hepatology 2008;48(1):204Y13
    • (2008) Hepatology , vol.48 , Issue.1 , pp. 204-213
    • Gines, P.1    Wong, F.2    Watson, H.3
  • 9
    • 33751005260 scopus 로고    scopus 로고
    • Tolvaptan, a selective oral vasopressin V2Yreceptor antagonist, for hyponatremia
    • Schrier RW, Gross P, Gheorghiade M, et al. Tolvaptan, a selective oral vasopressin V2Yreceptor antagonist, for hyponatremia. N Engl J Med 2006;355(20):2099Y112
    • (2006) N Engl J Med , vol.355 , Issue.20 , pp. 099-112
    • Schrier, R.W.1    Gross, P.2    Gheorghiade, M.3
  • 10
    • 0019433197 scopus 로고
    • Vasopressin analogs that antagonize antidiuretic responses by rats to the antidiuretic hormone
    • Sawyer WH, Pang PK, Seto J, et al. Vasopressin analogs that antagonize antidiuretic responses by rats to the antidiuretic hormone. Science 1981; 212(4490):49Y51
    • (1981) Science , vol.212 , Issue.4490 , pp. 49-51
    • Sawyer, W.H.1    Pang, P.K.2    Seto, J.3
  • 11
    • 0026533435 scopus 로고
    • Characterization of a novel aquaretic agent, OPCY31260, as an orally effective, nonpeptide vasopressin V2 receptor antagonist
    • Yamamura Y, Ogawa H, Yamashita H, et al. Characterization of a novel aquaretic agent, OPCY31260, as an orally effective, nonpeptide vasopressin V2 receptor antagonist. Br J Pharmacol 1992;105(4): 787Y91
    • (1992) Br J Pharmacol , vol.105 , Issue.4 , pp. 787-791
    • Yamamura, Y.1    Ogawa, H.2    Yamashita, H.3
  • 12
    • 0032240078 scopus 로고    scopus 로고
    • OPCY41061, a highly potent human vasopressin V2Yreceptor antagonist: Pharmacological profile and aquaretic effect by single and multiple oral dosing in rats
    • Yamamura Y, Nakamura S, Itoh S, et al. OPCY41061, a highly potent human vasopressin V2Yreceptor antagonist: Pharmacological profile and aquaretic effect by single and multiple oral dosing in rats. J Pharmacol Exp Ther 1998;287(3):860Y7
    • (1998) J Pharmacol Exp Ther , vol.287 , Issue.3 , pp. 860-867
    • Yamamura, Y.1    Nakamura, S.2    Itoh, S.3
  • 13
    • 83655212353 scopus 로고    scopus 로고
    • Efficacy and safety of tolvaptan in heart failure patients with volume overload despite the standard treatment with conventional diuretics: A phase III, randomized, doubleYblind, placeboYcontrolled study (QUEST study
    • Matsuzaki M, Hori M, Izumi T, et al. Efficacy and safety of tolvaptan in heart failure patients with volume overload despite the standard treatment with conventional diuretics: A phase III, randomized, doubleYblind, placeboYcontrolled study (QUEST study). Cardiovasc Drugs Ther 2011;25(suppl 1): S33Y45
    • (2011) Cardiovasc Drugs Ther , vol.25 , Issue.1
    • Matsuzaki, M.1    Hori, M.2    Izumi, T.3
  • 14
    • 77956923207 scopus 로고    scopus 로고
    • A multicenter, openYlabel, doseYranging study to exploratively evaluate the efficacy, safety, and doseYresponse of tolvaptan in patients with decompensated hepatic cirrhosis
    • Okita K, Sakaida I, Okada M, et al. A multicenter, openYlabel, doseYranging study to exploratively evaluate the efficacy, safety, and doseYresponse of tolvaptan in patients with decompensated hepatic cirrhosis. J Gastroenterol 2010;45(9):979Y87
    • (2010) J Gastroenterol , vol.45 , Issue.9 , pp. 979-987
    • Okita, K.1    Sakaida, I.2    Okada, M.3
  • 15
    • 84872245021 scopus 로고    scopus 로고
    • The pharmacokinetics and pharmacodynamics of tolvaptan in patients with liver cirrhosis with insufficient response to conventional diuretics: A multicentre, doubleYblind, parallelYgroup, phase III study
    • ASCITES Clinical Pharmacology Group
    • Sakaida I, Yanase M, Kobayashi Y, et al. ASCITES Clinical Pharmacology Group. The pharmacokinetics and pharmacodynamics of tolvaptan in patients with liver cirrhosis with insufficient response to conventional diuretics: A multicentre, doubleYblind, parallelYgroup, phase III study. J Int Med Res 2012;40(6):2381Y93
    • (2012) J Int Med Res , vol.40 , Issue.6 , pp. 2381-2393
    • Sakaida, I.1    Yanase, M.2    Kobayashi, Y.3
  • 16
    • 84887385576 scopus 로고    scopus 로고
    • Efficacy and safety of a 14Yday administration of tolvaptan in the treatment of patients with ascites in hepatic oedema
    • ASCITES 14YDay Administration Study Group
    • Sakaida I, Yamashita S, Kobayashi T, et al. ASCITES 14YDay Administration Study Group. Efficacy and safety of a 14Yday administration of tolvaptan in the treatment of patients with ascites in hepatic oedema. J Int Med Res 2013;41(3):835Y47
    • (2013) J Int Med Res , vol.41 , Issue.3 , pp. 835-847
    • Sakaida, I.1    Yamashita, S.2    Kobayashi, T.3
  • 17
    • 84891776986 scopus 로고    scopus 로고
    • DoseYfinding trial of tolvaptan in liver cirrhosis patients with hepatic edema: A randomized, doubleYblind, placeboYcontrolled trial
    • ASCITES DoseYFinding Trial Grou.p.
    • Okita K, Kawazoe S, Hasebe C, et al. ASCITES DoseYFinding Trial Group. DoseYfinding trial of tolvaptan in liver cirrhosis patients with hepatic edema: A randomized, doubleYblind, placeboYcontrolled trial. Hepatol Res 2014; 44(1):83Y91
    • (2014) Hepatol Res , vol.44 , Issue.1 , pp. 83-91
    • Okita, K.1    Kawazoe, S.2    Hasebe, C.3
  • 18
    • 84890930202 scopus 로고    scopus 로고
    • Tolvaptan for improvement of hepatic edema: A phase 3, multicenter, randomized, doubleYblind, placeboYcontrolled trial
    • ASCITESYDOUBLEBLIND Study Grou.p.
    • Sakaida I, Kawazoe S, Kajimura K, et al. ASCITESYDOUBLEBLIND Study Group. Tolvaptan for improvement of hepatic edema: A phase 3, multicenter, randomized, doubleYblind, placeboYcontrolled trial. Hepatol Res 2014;44(1):73Y82
    • (2014) Hepatol Res , vol.44 , Issue.1 , pp. 73-82
    • Sakaida, I.1    Kawazoe, S.2    Kajimura, K.3
  • 19
    • 84857368395 scopus 로고    scopus 로고
    • Tolvaptan, an oral vasopressin antagonist, in the treatment of hyponatremia in cirrhosis
    • Cárdenas A, Ginès P, Marotta P, et al. Tolvaptan, an oral vasopressin antagonist, in the treatment of hyponatremia in cirrhosis. J Hepatol 2012;56(3):571Y8
    • (2012) J Hepatol , vol.56 , Issue.3 , pp. 571-578
    • Cárdenas, A.1    Ginès, P.2    Marotta, P.3
  • 20
    • 84858202663 scopus 로고    scopus 로고
    • Effects of cyp3a4 inhibition and induction on the pharmacokinetics and pharmacodynamics of tolvaptan, a nonypeptide avp antagonist in healthy subjects
    • Shoaf SE, Bricmont P, Mallikaarjun S. Effects of CYP3A4 inhibition and induction on the pharmacokinetics and pharmacodynamics of tolvaptan, a nonYpeptide AVP antagonist in healthy subjects. Br J Clin Pharmacol 2012;73(4): 579Y87
    • (2012) Br J Clin Pharmacol , vol.73 , Issue.4 , pp. 579-587
    • Shoaf, S.E.1    Bricmont, P.2    Mallikaarjun, S.3
  • 21
    • 83655212308 scopus 로고    scopus 로고
    • Nonclinical pharmacokinetics of a new nonpeptide V2 receptor antagonist
    • Furukawa M, Umehara K, Kashiyama E. Nonclinical pharmacokinetics of a new nonpeptide V2 receptor antagonist. Tolvaptan Cardiovasc Drugs Ther 2011; 25(suppl 1):S83Y9
    • (2011) Tolvaptan Cardiovasc Drugs Ther , vol.25 , Issue.1
    • Furukawa, M.1    Umehara, K.2    Kashiyama, E.3
  • 22
    • 84856072014 scopus 로고    scopus 로고
    • Absolute bioavailability of tolvaptan and determination of minimally effective concentrations in healthy subjects
    • Shoaf SE, Bricmont P, Mallikaarjun S. Absolute bioavailability of tolvaptan and determination of minimally effective concentrations in healthy subjects. Int J Clin Pharmacol Ther 2012;50(2):150Y6
    • (2012) Int J Clin Pharmacol Ther , vol.50 , Issue.2 , pp. 150-156
    • Shoaf, S.E.1    Bricmont, P.2    Mallikaarjun, S.3
  • 23
    • 83655198303 scopus 로고    scopus 로고
    • Pharmacokinetics, pharmacodynamics and safety of tolvaptan, a novel, oral, selective nonpeptide AVP V2Yreceptor antagonist: Results of singleY and multipleYdose studies in healthy Japanese male volunteers
    • Kim SR, Hasunuma T, Sato O, et al. Pharmacokinetics, pharmacodynamics and safety of tolvaptan, a novel, oral, selective nonpeptide AVP V2Yreceptor antagonist: Results of singleY and multipleYdose studies in healthy Japanese male volunteers. Cardiovasc Drugs Ther 2011;25(suppl 1): S5YS17
    • (2011) Cardiovasc Drugs Ther , vol.25 , Issue.1
    • Kim, S.R.1    Hasunuma, T.2    Sato, O.3
  • 24
    • 84903187666 scopus 로고    scopus 로고
    • Pharmacokinetics, pharmacodynamics, and safety of tolvaptan, a nonpeptide AVP antagonist, during ascending singleYdose studies in healthy subjects
    • Shoaf SE, Wang Z, Bricmont P, et al. Pharmacokinetics, pharmacodynamics, and safety of tolvaptan, a nonpeptide AVP antagonist, during ascending singleYdose studies in healthy subjects. J Clin Pharmacol 2007;7(12):1498Y507
    • (2007) J Clin Pharmacol , vol.7 , Issue.12 , pp. 498-507
    • Shoaf, S.E.1    Wang, Z.2    Bricmont, P.3
  • 25
    • 24944580978 scopus 로고    scopus 로고
    • A new, accurate and conventional fiveYpoint method for quantitative evaluation of ascites using plain computed tomography in cancer patients
    • Oriuchi N, Nakajima T, Mochiki E, et al. A new, accurate and conventional fiveYpoint method for quantitative evaluation of ascites using plain computed tomography in cancer patients. Jpn J Clin Oncol 2005;35(7): 386Y90
    • (2005) Jpn J Clin Oncol , vol.35 , Issue.7 , pp. 386-390
    • Oriuchi, N.1    Nakajima, T.2    Mochiki, E.3
  • 26
    • 84890930202 scopus 로고    scopus 로고
    • Correlation between changes in bodyweight and changes in ascites volume in liver cirrhosis patients with hepatic edema in shortYterm diuretic therapy
    • Sakaida I, Okita K. Correlation between changes in bodyweight and changes in ascites volume in liver cirrhosis patients with hepatic edema in shortYterm diuretic therapy. Hepatol Res 2014;44(1):73Y82
    • (2014) Hepatol Res , vol.44 , Issue.1 , pp. 73-82
    • Sakaida, I.1    Okita, K.2
  • 27
    • 77955850168 scopus 로고    scopus 로고
    • Spontaneous bacterial peritonitis, and hepatorenal syndrome in cirrhosis european association for the study of the liver
    • EASL clinical practice guidelines on the management of ascites
    • EASL clinical practice guidelines on the management of ascites. spontaneous bacterial peritonitis, and hepatorenal syndrome in cirrhosis. European Association for the Study of the Liver. J Hepatol 2010; 53(3):397Y417
    • (2010) J Hepatol , vol.53 , Issue.3 , pp. 397-417
  • 28
    • 0031783252 scopus 로고    scopus 로고
    • Hyponatremia in cirrhosis: From pathogenesis to treatment
    • Gine's P, Berl T, Bernardi M, et al. Hyponatremia in cirrhosis: From pathogenesis to treatment. Hepatology 1998;28(3):851Y64
    • (1998) Hepatology , vol.28 , Issue.3 , pp. 851-864
    • Gine's, P.1    Berl, T.2    Bernardi, M.3
  • 29
    • 16244422677 scopus 로고    scopus 로고
    • Addition of serum sodium into the MELD score predicts waiting list mortality better than MELD alone
    • Ruf AE, Kremers WK, Chavez LL, et al. Addition of serum sodium into the MELD score predicts waiting list mortality better than MELD alone. Liver Transpl 2005; 11(3):336Y43
    • (2005) Liver Transpl , vol.11 , Issue.3 , pp. 336-343
    • Ruf, A.E.1    Kremers, W.K.2    Chavez, L.L.3
  • 30
    • 4644301244 scopus 로고    scopus 로고
    • Persistent ascites and low serum sodium identify patients with cirrhosis and low MELD scores who are at high risk for early death
    • Heuman DM, AbouYAssi SG, Habib A, et al. Persistent ascites and low serum sodium identify patients with cirrhosis and low MELD scores who are at high risk for early death. Hepatology 2004;40(4):802Y10
    • (2004) Hepatology , vol.40 , Issue.4 , pp. 802-810
    • Heuman, D.M.1    Abou, Y.2    Assi, S.G.3    Habib, A.4
  • 31
    • 11244299379 scopus 로고    scopus 로고
    • Serum sodium predicts mortality in patients listed for liver transplantation
    • Biggins SW, Rodriguez HJ, Bacchetti P, et al. Serum sodium predicts mortality in patients listed for liver transplantation. Hepatology 2005;41(1):32Y9
    • (2005) Hepatology , vol.41 , Issue.1
    • Biggins, S.W.1    Rodriguez, H.J.2    Bacchetti, P.3
  • 32
    • 33646372427 scopus 로고    scopus 로고
    • EvidenceYbased incorporation of serum sodium concentration into MELD
    • Biggins SW, Kim WR, Terrault NA, et al. EvidenceYbased incorporation of serum sodium concentration into MELD. Gastroenterology 2006;130(6):1652Y60
    • (2006) Gastroenterology , vol.130 , Issue.6 , pp. 1652-1660
    • Biggins, S.W.1    Kim, W.R.2    Terrault, N.A.3
  • 33
    • 33846074784 scopus 로고    scopus 로고
    • Drug insight: The role of albumin in the management of chronic liver disease
    • Wong F. Drug insight: The role of albumin in the management of chronic liver disease. Nat Clin Pract Gastroenterol Hepatol 2007; 4(1):43Y51
    • (2007) Nat Clin Pract Gastroenterol Hepatol , vol.4 , Issue.1 , pp. 43-51
    • Wong, F.1
  • 34
    • 0344308514 scopus 로고    scopus 로고
    • Mechanisms of water and sodium retention in cirrhosis and the pathogenesis of ascites
    • Cárdenas A, Arroyo V. Mechanisms of water and sodium retention in cirrhosis and the pathogenesis of ascites. Best Pract Res Clin Endocrinol Metab 2003;17(4):607Y22
    • (2003) Best Pract Res Clin Endocrinol Metab , vol.17 , Issue.4 , pp. 607-622
    • Cárdenas, A.1    Arroyo, V.2
  • 35
    • 0033037767 scopus 로고    scopus 로고
    • Albumin improves the response to diuretics in patients with cirrhosis and ascites: Results of a randomized, controlled trial
    • Gentilini P, CasiniYRaggi V, Di Fiore G, et al. Albumin improves the response to diuretics in patients with cirrhosis and ascites: Results of a randomized, controlled trial. J Hepatol 1999;30(4):639Y45
    • (1999) J Hepatol , vol.30 , Issue.4 , pp. 639-645
    • Gentilini, P.1    Casini, Y.2    Raggi, V.3    Di Fiore, G.4
  • 36
    • 33645526109 scopus 로고    scopus 로고
    • LongYterm albumin infusion improves survival in patients with cirrhosis and ascites: An unblinded randomized trial
    • Romanelli RG, La Villa G, Barletta G, et al. LongYterm albumin infusion improves survival in patients with cirrhosis and ascites: An unblinded randomized trial. World J Gastroenterol 2006;12(9):1403Y7
    • (2006) World J Gastroenterol , vol.12 , Issue.9 , pp. 1403-1407
    • Romanelli, R.G.1    La Villa, G.2    Barletta, G.3
  • 37
    • 0023184267 scopus 로고
    • Mechanism of furosemide resistance in analbuminemic rats and hypoalbuminemic patients
    • Inoue M, Okajima K, Itoh K, et al. Mechanism of furosemide resistance in analbuminemic rats and hypoalbuminemic patients. Kidney Int 1987;32(2):198Y203
    • (1987) Kidney Int , vol.32 , Issue.2 , pp. 198-203
    • Inoue, M.1    Okajima, K.2    Itoh, K.3
  • 38
    • 1042269718 scopus 로고    scopus 로고
    • Review article: Albumin as a drugYbiological effects of albumin unrelated to oncotic pressure
    • Evans TW. Review article: Albumin as a drugYbiological effects of albumin unrelated to oncotic pressure. Aliment Pharmacol Ther 2002;16(suppl 5):6Y11
    • (2002) Aliment Pharmacol Ther , vol.16 , Issue.5 , pp. 6-11
    • Evans, T.W.1
  • 39
    • 33644825770 scopus 로고    scopus 로고
    • Treatment of hepatorenal syndrome as defined by the international ascites club by albumin and furosemide infusion according to the central venous pressure: A prospective pilot study
    • Péron JM, Bureau C, Gonzalez L, et al. Treatment of hepatorenal syndrome as defined by the international ascites club by albumin and furosemide infusion according to the central venous pressure: A prospective pilot study. Am J Gastroenterol 2005; 100(12):2702Y7
    • (2005) Am J Gastroenterol , vol.100 , Issue.12 , pp. 702-707
    • Péron, J.M.1    Bureau, C.2    Gonzalez, L.3
  • 40
    • 77955306270 scopus 로고    scopus 로고
    • Effects of a selective vasopressin V2 receptor antagonist, satavaptan, on ascites recurrence after paracentesis in patients with cirrhosis
    • Wong F, Gines P, Watson H, et al. Effects of a selective vasopressin V2 receptor antagonist, satavaptan, on ascites recurrence after paracentesis in patients with cirrhosis. J Hepatol 2010;53(2):283Y90.
    • (2010) J Hepatol , vol.53 , Issue.2 , pp. 283-290
    • Wong, F.1    Gines, P.2    Watson, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.