A mixed methods feasibility study to evaluate the use of a low-intensity, nurse-delivered cognitive behavioural therapy for the treatment of irritable bowel syndrome

BMJ Open

Volumn 4, Issue 6, 2014, Pages

  Dainty, Andrew David ^a   Fox, Mark ^b   Lewis, Nina ^c   Hunt, Melissa ^d   Holtham, Elizabeth ^e   Timmons, Stephen ^a   Kinsella, Philip ^a   Wragg, Andrew ^c   Callaghan, Patrick ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^c NOTTINGHAM UNIVERSITY HOSPITALS NHS TRUST   (United Kingdom)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ANXIETY; ARTICLE; CLINICAL PRACTICE; COGNITIVE THERAPY; DEPRESSION; FEASIBILITY STUDY; FEMALE; FOLLOW UP; HEALTH CARE DELIVERY; HUMAN; IRRITABLE COLON; MAJOR CLINICAL STUDY; MALE; PATIENT ATTITUDE; QUALITATIVE ANALYSIS; QUALITY OF LIFE; QUANTITATIVE ANALYSIS; RANDOMIZED CONTROLLED TRIAL (TOPIC); REGISTERED NURSE; SECONDARY HEALTH CARE; SELF HELP; THEMATIC ANALYSIS; CONTROLLED STUDY; IRRITABLE BOWEL SYNDROME; METHODOLOGY; NURSING; PROCEDURES; RANDOMIZED CONTROLLED TRIAL; SINGLE BLIND PROCEDURE;

COGNITIVE THERAPY; FEASIBILITY STUDIES; FEMALE; HUMANS; IRRITABLE BOWEL SYNDROME; MALE; RESEARCH DESIGN; SINGLE-BLIND METHOD;

EID: 84903196731     PISSN: None     EISSN: 20446055     Source Type: Journal    
DOI: 10.1136/bmjopen-2014-005262     Document Type: Article

References (68)

1. Schmulson M, Chang L. Diagnostic approach to the patient with irritable bowel syndrome. Am J Med 1999;107:20-6.
2. Spiller R, Garsed K. Postinfectious irritable bowel syndrome. Gastroenterology 2009;136:1979-88.
3. DuPont A. Postinfectious irritable bowel syndrome. Clin Infect Dis 2008;46:594-9. (Pubitemid 351263502)
4. Yang J, Fox M, Cong Y, et al. Lactose intolerance in irritable bowel syndrome patients with diarrhoea: the roles of anxiety, activation of the innate mucosal immune system and visceral sensitivity. Aliment Pharmacol Ther 2014;39:302-11.
5. O'Mahony L, McCarthy J, Kelly P, et al. Lactobacillus and bifidobacterium in irritable bowel syndrome: symptom responses and relationship to cytokine profiles. Gastroenterology 2005;128:541-51. (Pubitemid 40585355)
6. North C, Hong B, Alpers D. Relationship of functional gastrointestinal disorders and psychiatric disorders: implications for treatment. World J Gastroenterol 2007;13:2020-7. (Pubitemid 46795836)
7. Halder S, Fett S, Locke G, et al. Impact of functional gastrointestinal disorders on health-related quality of life: a population-based case-control study. Aliment Pharmacol Ther 2004;19:233-42. (Pubitemid 38174892)
8. Canavan C, West J, Card T. The epidemiology of irritable bowel syndrome. Clin Epidemiol 2014;4:67-80.
9. Longstreth G, Wilson A, Knight K, et al. Irritable bowel syndrome, health care use, and costs: a U.S. managed care perspective. Am J Gastroenterol 2003;98:600-7. (Pubitemid 36348532)
10. Hatcher S, Arroll B. Assessment and management of medically unexplained symptoms. BMJ 2008;336:1124-8. (Pubitemid 351731744)
11. Levy R, Olden K, Naliboff B, et al. Psychosocial aspects of the functional gastrointestinal disorders. Gastroenterology 2006;130:1447-58.
12. Ryle J. An address on chronic spasmodic affections of the colon and the diseases which they simulate. Lancet 1928;212:1115-19.
13. Guthrie E, Barlow J, Fernandes L, et al . Changes in tolerance to rectal distension correlate with changes in psychological state in patients with severe irritable bowel syndrome. Psychosom Med 2004;66:578-82. (Pubitemid 38971254)
14. Dainty A. Irritable bowel syndrome: psychological comorbidities and cognitive behavioural therapy. A review of the literature. Gastrointest Nurs 2012;10:44-50.
15. Drossman D, Thompson W, Talley N, et al . Identification of subgroups of functional gastrointestinal disorders. Gastroenterol Int 1990;3:159-72.
16. Delvaux M, Denis P, Allemand H. Sexual and physical abuses are more frequently reported by IBS patients than by patients with organic digestive diseases or controls. Eur J Gastroenterol Hepatol 1997;9:345-52. (Pubitemid 27188632)
17. Creed F, Craig T, Farmer R. Functional abdominal pain, psychiatric illness and life events. Gut 1988;29:235-42. (Pubitemid 18078894)
18. NICE. Irritable bowel syndrome in adults: diagnosis and management of irritable bowel syndrome in primary care. London: National Institute for Health and Clinical Excellence, 2008.
19. Hunt M, Moshier S, Milonova M. Brief cognitive-behavioral internet therapy for irritable bowel syndrome. Behav Res Ther 2009;47:797-802.
20. Hassett A, Gevirtz R. Nonpharmacologic treatment for fibromyalgia: patient education, cognitive-behavioral therapy, relaxation techniques, and complementary and alternative medicine. Rheum Dis Clin N Am 2009;35:393-407.
21. Beck A, Rush A, Shaw B, et al. Cognitive therapy of depression: a treatment manual. New York: Guilford, 1979.
22. Craske M, Wolitzky-Taylor K, Labus J, et al. A cognitive-behavioral treatment for irritable bowel syndrome using interoceptive exposure to visceral sensations. Behav Res Ther 2011;49:413-21.
23. Drossman D, Toner B, Whitehead W, et al. Cognitive-behavioral therapy versus education and desipramine versus placebo for moderate to severe functional bowel disorders. Gastroenterology 2003;125:19-31. (Pubitemid 36799103)
24. Kennedy T, Jones R, Darnley S, et al. Cognitive behaviour therapy in addition to antispasmodic treatment for irritable bowel syndrome in primary care: randomised controlled trial. BMJ 2005;331:435-7. (Pubitemid 41176381)
25. Zijdenbos I, De Wit N, Van der Heijden G, et al. Cochrane review: psychological treatments for the management of irritable bowel syndrome. Chichester, UK: John Wiley & Sons, 2009.
26. Lackner J, Jaccard J, Krasner S, et al. Self-administered cognitive behavior therapy for moderate to severe irritable bowel syndrome: clinical efficacy, tolerability, feasibility. Clin Gastroenterol Hepatol 2008;6:899-906.
27. Clark D. Implementing NICE guidelines for the psychological treatment of depression and anxiety disorders: the IAPT experience. Int Rev Psychiatry 2011;23:375-84.
28. Jadad A. Randomised controlled trials: a user 's guide. London: BMJ Books, 1998.
29. Muir-Gray J. Evidence based healthcare. New York: Churchill Livingstone, 1997.
30. Johnson B, Onwuegbuzie A. Mixed methods research: a research paradigm whose time has come. Educ Res 2004;33:14-26. (Pubitemid 39519587)
31. Creswell J, Plano-Clark V. Designing and conducting mixed methods research. What is mixed methods research? Thousand Oaks, CA: Sage, 2007.
32. Scott P, Briggs J. A pragmatist argument for mixed methodology in medical informatics. J Mixed Methods Res 2009;3:223-41.
33. Anaf S, Sheppard L. Mixing research methods in health professional degrees: thoughts for undergraduate students and supervisors. Qual Rep 2007;12:184-92.
34. Creswell J, Plano-Clark V. Understanding mixed methods research. In: Creswell J, Plano-Clark V, eds. Designing and conducting mixed methods research. Thousand Oaks, CA: Sage, 2007: 1-19.
35. Denzin N, Lincoln Y. The discipline and practice of qualitative research. In: Denzin N, Lincoln Y, eds. Handbook of qualitative research. Thousand Oaks, CA: Sage, 2000.
36. Pluye P, Gagnon M, Griffiths F, et al. A scoring system for appraising mixed methods research, and concomitantly appraising qualitative, quantitative and mixed methods primary studies in mixed studies reviews. Int J Nurs Stud 2009;46:529-46.
37. Wagner K, Davidson P, Pollini R, et al. Reconciling incongruous qualitative and quantitative findings in mixed methods research: exemplars from research with drug using populations. Int J Drug Policy 2012;23:54-61.
38. Spiller R, Aziz Q, Creed F, et al. Guidelines on the irritable bowel syndrome: mechanisms and practical management. Gut 2007;56:1770-98. (Pubitemid 350206308)
39. Kumano H, Kaiya H, Yoshiuchi K, et al. Comorbidity of irritable bowel syndrome, panic disorder, and agoraphobia in a Japanese representative sample. Am J Gastroenterol 2004;99:370-6. (Pubitemid 38279883)
40. The Rome Foundation. To improve the lives of people with functional GI disorders. 2012. http://www.romecriteria.org/ (accessed 13 Jul 2012).
41. Ljótsson B, Hedman E, Andersson E, et al. Internet-delivered exposure-based treatment vs. stress management for irritable bowel syndrome: a randomized trial. Am J Gastroenterol 2011;106:1481-91.
42. Blanchard E, Lackner J, Sanders K, et al. A controlled evaluation of group cognitive therapy in the treatment of irritable bowel syndrome. Behav Res Ther 2007;45:633-48. (Pubitemid 46282624)
43. Drossman D. The functional gastrointestinal disorders and the Rome III process. Gastroenterology 2006;130:1377-90.
44. Andersson E, Ljótsson B, Smit F, et al. Cost-effectiveness of internet-based cognitive behavior therapy for irritable bowel syndrome: results from a randomized controlled trial. BMC Public Health 2011;11:215.
45. Heymann-Mönnikes I, Arnold R, Florin I, et al. The combination of medical treatment plus multicomponent behavioral therapy is superior to medical treatment alone in the therapy of irritable bowel syndrome. Am J Gastroenterol 2000;95:981-94. (Pubitemid 30196735)
46. Childress C. Potential risks and benefits of online psychotherapeutic interventions. 1998. http://www.ismho.org/potential-risks-and-benefits.asp (accessed 10 Jan 2013).
47. Mohr D, Siddique J, Ho J, et al. Interest in behavioral and psychological treatments delivered face-to-face, by telephone, and by internet. Ann Behav Med 2010;40:89-98.
48. Toner B, Segal Z, Emmott S, et al. Cognitive-behavioral treatment of irritable bowel syndrome: the brain-gut connection. New York: Guilford Press, 2000.
49. IAPT. National curriculum for the education of Psychological Wellbeing Practitioners (PWPS). 2011. http://www.iapt.nhs.uk/silo/files/national- curriculum-for-the-education-of-psychological-wellbeing-practitioners-pwps-.pdf (accessed 28 Feb 2013).
50. Gralnek I, Hays R, Kilbourne A, et al. The impact of irritable bowel syndrome on health-related quality of life. Gastroenterology 2000;119:654-60.
51. El-Serag H, Olden K, Bjorkman D. Health-related quality of life among persons with irritable bowel syndrome: a systematic review. Aliment Pharmacol Ther 2002;16:1171-85. (Pubitemid 34680762)
52. Wiklund I, Fullerton S, Hawkey C, et al. An irritable bowel syndrome specific symptom questionnaire: development and validation. Scand J Gastroenterol 2003;38:947-54. (Pubitemid 37153623)
53. Patrick D, Drossman D, Frederick I, et al. Quality of life in persons with irritable bowel syndrome: development and validation of a new measure. Dig Dis Sci 1998;43:400-11. (Pubitemid 28124621)
54. Lydiard R, Falsetti S. Experience with anxiety and depression treatment studies: implications for designing irritable bowel syndrome clinical trials. Am J Med 1999;107:65-73.
55. Kroenke K, Spitzer R, Williams J. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med 2001;16:606-13. (Pubitemid 32823891)
56. Löwe B, Decker O, Müller S, et al. Validation and standardization of the Generalized Anxiety Disorder screener (GAD-7) in the general population. Med Care 2008;46:266-74.
57. Nespor J, Barylske J. Narrarive discourse and teacher knowledge. Am Educ J 1991;28:805-23.
58. Huberman A, Miles M. Assessing local causality in qualitative research. In: Berg D, Smith K, eds. The self in social inquiry: researching methods. Newbury Park, CA: Sage, 1988:351-81.
59. McNamara C. General guidelines for conducting interviews. 2009. http://managementhelp.org/evaluatn/intrview.htm (accessed 17 May 2012).
60. Parahoo K. Nursing research: principles, process and issues. Hampshire: Palgrave Macmillan, 2006.
61. Doyle L, Brady A, Byrne G. An overview of mixed methods research. J Res Nurs 2009;14:175-85.
62. Creswell J. Mixed methods procedures. In: Creswell J, ed. Research design: qualitative, quantitative and mixed methods approaches. London: Sage, 2009:203-36.
63. Ritchie J, Spencer L. Qualitative data analysis for applied policy research. In: Bryman A, Burgess R, eds. Analysing qualitative data. London: Routledge, 1994:173-94.
64. Gunaratnam Y. Narrative and stories in health care. 2009. http://goldsmiths.academia.edu/YasminGunaratnam/Papers/386158/ Narrative-Interviews-and-Research (accessed 17 May 2012).
65. NIHR. What is patient and public involvement in research? 2012. http://www.peopleinresearch.org/find-out-about-involvement/what-is-public- involvement-in-research/ (accessed 6 Apr 2012).
66. NIHR. Health Technology Assessment programme. 2012. http://www.hta.ac.uk/ PPIguidance/ (accessed 6 Apr 2012).
67. Oliver S. How can health service users contribute to the NHS research and development agenda? BMJ 1995;310:1315-18.
68. Toner B. Cognitive-behavioral treatment of functional somatic syndromes: integrating gender issues. Cogn Behav Pract 1994;1:157-78.