-
1
-
-
84874299131
-
Modern subunit vaccines: Development, components, and research opportunities
-
Moyle, P. M. & Toth, I. Modern subunit vaccines: development, components, and research opportunities. ChemMedChem 8, 360-376 (2013).
-
(2013)
ChemMedChem
, vol.8
, pp. 360-376
-
-
Moyle, P.M.1
Toth, I.2
-
2
-
-
77955597687
-
Unmet needs in modern vaccinology: Adjuvants to improve the immune response
-
Leroux-Roels, G. Unmet needs in modern vaccinology: adjuvants to improve the immune response. Vaccine 28, C25-C36 (2010).
-
(2010)
Vaccine
, vol.28
-
-
Leroux-Roels, G.1
-
3
-
-
58149216348
-
New horizons in adjuvants for vaccine development
-
Reed, S. G. et al. New horizons in adjuvants for vaccine development. Trends Immunol. 30, 23-32 (2009).
-
(2009)
Trends Immunol.
, vol.30
, pp. 23-32
-
-
Reed, S.G.1
-
4
-
-
0026033441
-
And characterization of saponins with adjuvant activity from Quillaja saponaria Molina cortex
-
Kensil, C. R., Patel, U., Lennick, M. & Marciani, D. Separation and characterization of saponins with adjuvant activity from Quillaja saponaria Molina cortex. J. Immunol. 146, 431-437 (1991).
-
(1991)
J. Immunol.
, vol.146
, pp. 431-437
-
-
Kensil, C.R.1
Patel, U.2
Lennick, M.3
Separation, M.D.4
-
5
-
-
0010993390
-
Comparison of the effect of different immunological adjuvants on the antibody and T-cell response to immunization with MUC1-KLH and GD3-KLH conjugate cancer vaccines
-
Kim, S. K. et al. Comparison of the effect of different immunological adjuvants on the antibody and T-cell response to immunization with MUC1-KLH and GD3-KLH conjugate cancer vaccines. Vaccine 18, 597-603 (1999).
-
(1999)
Vaccine
, vol.18
, pp. 597-603
-
-
Kim, S.K.1
-
6
-
-
0027203490
-
Adjuvant activity of QS-21 isomers
-
Soltysik, S., Bedore, D. A. & Kensil, C. R. Adjuvant activity of QS-21 isomers. Ann. NY Acad. Sci. 690, 392-395 (1993).
-
(1993)
Ann. NY Acad. Sci.
, vol.690
, pp. 392-395
-
-
Soltysik, S.1
Bedore, D.A.2
Kensil, C.R.3
-
8
-
-
79955112512
-
Natural and synthetic saponin adjuvant QS-21 for vaccines against cancer
-
Ragupathi, G., Gardner, J. R., Livingston, P. O. & Gin, D. Y. Natural and synthetic saponin adjuvant QS-21 for vaccines against cancer. Expert Rev. Vaccines 10, 463-470 (2011).
-
(2011)
Expert Rev. Vaccines
, vol.10
, pp. 463-470
-
-
Ragupathi, G.1
Gardner, J.R.2
Livingston, P.O.3
Gin, D.Y.4
-
9
-
-
81455154875
-
First results of Phase 3 trial of RTS,S/AS01 malaria vaccine in African children
-
Agnandji, S. T. et al. First results of Phase 3 trial of RTS,S/AS01 malaria vaccine in African children. New Engl. J. Med. 365, 1863-1875 (2011).
-
(2011)
New Engl. J. Med.
, vol.365
, pp. 1863-1875
-
-
Agnandji, S.T.1
-
10
-
-
48449105674
-
The safety and tolerability of an HIV-1 DNA prime-protein boost vaccine (DP6-001) in healthy adult volunteers
-
Kennedy, J. S. et al. The safety and tolerability of an HIV-1 DNA prime-protein boost vaccine (DP6-001) in healthy adult volunteers. Vaccine 26, 4420-4424 (2008).
-
(2008)
Vaccine
, vol.26
, pp. 4420-4424
-
-
Kennedy, J.S.1
-
11
-
-
39249083535
-
Vaccine adjuvant systems containing monophosphoryl lipid A and QS21 induce strong and persistent humoral and T cell responses against hepatitis B surface antigen in healthy adult volunteers
-
Vandepapeliere, P. et al. Vaccine adjuvant systems containing monophosphoryl lipid A and QS21 induce strong and persistent humoral and T cell responses against hepatitis B surface antigen in healthy adult volunteers. Vaccine 26, 1375-1386 (2008).
-
(2008)
Vaccine
, vol.26
, pp. 1375-1386
-
-
Vandepapeliere, P.1
-
12
-
-
70349551599
-
The candidate tuberculosis vaccine Mtb72F/AS02A: Tolerability and immunogenicity in humans
-
Von Eschen, K. et al. The candidate tuberculosis vaccine Mtb72F/AS02A: tolerability and immunogenicity in humans. Hum. Vaccin. 5, 475-482 (2009).
-
(2009)
Hum. Vaccin.
, vol.5
, pp. 475-482
-
-
Von Eschen, K.1
-
13
-
-
64549152492
-
Long-Term follow-up of patients immunized with AN1792: Reduced functional decline in antibody responders
-
Vellas, B. et al. Long-term follow-up of patients immunized with AN1792: reduced functional decline in antibody responders. Curr. Alzheimer Res. 6, 144-151 (2009).
-
(2009)
Curr. Alzheimer Res.
, vol.6
, pp. 144-151
-
-
Vellas, B.1
-
14
-
-
14944364716
-
Synthesis of the potent immunostimulatory adjuvant QS-21A
-
Wang, P., Kim, Y. J., Navarro-Villalobos, M., Rohde, B. D. & Gin, D. Y. Synthesis of the potent immunostimulatory adjuvant QS-21A. J. Am. Chem. Soc. 127, 3256-3257 (2005).
-
(2005)
J. Am. Chem. Soc.
, vol.127
, pp. 3256-3257
-
-
Wang, P.1
Kim, Y.J.2
Navarro-Villalobos, M.3
Rohde, B.D.4
Gin, D.Y.5
-
15
-
-
52049115713
-
Synthesis of QS-21-xylose: Establishment of the immunopotentiating activity of synthetic QS-21 adjuvant with a melanoma vaccine
-
Deng, K. et al. Synthesis of QS-21-xylose: establishment of the immunopotentiating activity of synthetic QS-21 adjuvant with a melanoma vaccine. Angew. Chem. Int. Ed. 47, 6395-6398 (2008).
-
(2008)
Angew. Chem. Int. Ed.
, vol.47
, pp. 6395-6398
-
-
Deng, K.1
-
16
-
-
77249153218
-
Design and synthesis of potent quillaja saponin vaccine adjuvants
-
Adams, M. M. et al. Design and synthesis of potent Quillaja saponin vaccine adjuvants. J. Am. Chem. Soc. 132, 1939-1945 (2010).
-
(2010)
J. Am. Chem. Soc.
, vol.132
, pp. 1939-1945
-
-
Adams, M.M.1
-
17
-
-
84865128783
-
Synthesis and preclinical evaluation of QS-21 variants leading to simplified vaccine adjuvants and mechanistic probes
-
Chea, E. K. et al. Synthesis and preclinical evaluation of QS-21 variants leading to simplified vaccine adjuvants and mechanistic probes. J. Am. Chem. Soc. 134, 13448-13457 (2012).
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 13448-13457
-
-
Chea, E.K.1
-
18
-
-
0028800377
-
Structure/function studies of QS-21 adjuvant: Assessment of triterpene aldehyde and glucuronic acid roles in adjuvant function
-
Soltysik, S. et al. Structure/function studies of QS-21 adjuvant: assessment of triterpene aldehyde and glucuronic acid roles in adjuvant function. Vaccine 13, 1403-1410 (1995).
-
(1995)
Vaccine
, vol.13
, pp. 1403-1410
-
-
Soltysik, S.1
-
19
-
-
0000466378
-
Radioiodination techniques for small organic molecules
-
Seevers, R. H. & Counsell, R. E. Radioiodination techniques for small organic molecules. Chem. Rev. 82, 575-590 (1982).
-
(1982)
Chem. Rev.
, vol.82
, pp. 575-590
-
-
Seevers, R.H.1
Counsell, R.E.2
-
20
-
-
79960413988
-
+T cells
-
+ T cells. J. Immunol. 187, 55-63 (2011).
-
(2011)
J. Immunol.
, vol.187
, pp. 55-63
-
-
Duewell, P.1
-
21
-
-
0021925427
-
Adjuvant activity of saponin: Antigen localization studies
-
Scott, M. T., Goss-Sampson, M. & Bomford, R. Adjuvant activity of saponin: antigen localization studies. Int. Arch. Allergy Appl. Immunol. 77, 409-412 (1985).
-
(1985)
Int. Arch. Allergy Appl. Immunol.
, vol.77
, pp. 409-412
-
-
Scott, M.T.1
Goss-Sampson, M.2
Bomford, R.3
-
23
-
-
33845222410
-
Assessment of the monoterpene, glycidic and triterpene-moieties' contributions to the adjuvant function of the CP05 saponin of Calliandra pulcherrima Benth during vaccination against experimental visceral leishmaniasis
-
Nico, D., Santos, F. N., Borja-Cabrera, G. P., Palatnik, M. & Palatnik de Sousa, C. B. Assessment of the monoterpene, glycidic and triterpene-moieties' contributions to the adjuvant function of the CP05 saponin of Calliandra pulcherrima Benth during vaccination against experimental visceral leishmaniasis. Vaccine 25, 649-658 (2007).
-
(2007)
Vaccine
, vol.25
, pp. 649-658
-
-
Nico, D.1
Santos, F.N.2
Borja-Cabrera, G.P.3
Palatnik, M.4
De Sousa, C.B.P.5
-
24
-
-
84355162745
-
Saponins from the spanish saffron crocus sativus are efficient adjuvants for protein-based vaccines
-
Castro-Diaz, N. et al. Saponins from the Spanish saffron Crocus sativus are efficient adjuvants for protein-based vaccines. Vaccine 30, 388-397 (2012).
-
(2012)
Vaccine
, vol.30
, pp. 388-397
-
-
Castro-Diaz, N.1
-
25
-
-
0343114291
-
Adjuvant and haemolytic activities of 47 saponins derived from medicinal and food plants
-
Oda, K. et al. Adjuvant and haemolytic activities of 47 saponins derived from medicinal and food plants. Biol. Chem. 381, 67-74 (2000).
-
(2000)
Biol. Chem.
, vol.381
, pp. 67-74
-
-
Oda, K.1
-
26
-
-
2442561499
-
Fourth meeting on novel adjuvants currently in/close to human clinical testing
-
Pink, J. R. & Kieny, M. P. Fourth meeting on novel adjuvants currently in/close to human clinical testing. Vaccine 22, 2097-2102 (2004).
-
(2004)
Vaccine
, vol.22
, pp. 2097-2102
-
-
Pink, J.R.1
Kieny, M.P.2
-
28
-
-
0141889064
-
Vaccine adjuvants: Role and mechanisms of action in vaccine immunogenicity
-
Marciani, D. J. Vaccine adjuvants: role and mechanisms of action in vaccine immunogenicity. Drug Discov. Today 8, 934-943 (2003).
-
(2003)
Drug Discov. Today
, vol.8
, pp. 934-943
-
-
Marciani, D.J.1
-
29
-
-
28544449847
-
Divergent immunoglobulin G subclass activity through selective Fc receptor binding
-
Nimmerjahn, F. & Ravetch, J. V. Divergent immunoglobulin G subclass activity through selective Fc receptor binding. Science 310, 1510-1512 (2005).
-
(2005)
Science
, vol.310
, pp. 1510-1512
-
-
Nimmerjahn, F.1
Ravetch, J.V.2
-
30
-
-
0031661414
-
QS-21: A water-soluble triterpene glycoside adjuvant
-
Kensil, C. R. & Kammer, R. QS-21: a water-soluble triterpene glycoside adjuvant. Exp. Opin. Invest. Drugs 7, 1475-1482 (1998).
-
(1998)
Exp. Opin. Invest. Drugs
, vol.7
, pp. 1475-1482
-
-
Kensil, C.R.1
Kammer, R.2
-
31
-
-
0020025539
-
Studies on the cellular site of action of the adjuvant activity of saponin for sheep erythrocytes
-
Bomford, R. Studies on the cellular site of action of the adjuvant activity of saponin for sheep erythrocytes. Int. Arch. Allergy Appl. Immunol. 67, 127-131 (1982).
-
(1982)
Int. Arch. Allergy Appl. Immunol.
, vol.67
, pp. 127-131
-
-
Bomford, R.1
-
32
-
-
79952704589
-
Vaccine adjuvants alum and MF59 induce rapid recruitment of neutrophils and monocytes that participate in antigen transport to draining lymph nodes
-
Calabro, S. et al. Vaccine adjuvants alum and MF59 induce rapid recruitment of neutrophils and monocytes that participate in antigen transport to draining lymph nodes. Vaccine 29, 1812-1823 (2011).
-
(2011)
Vaccine
, vol.29
, pp. 1812-1823
-
-
Calabro, S.1
-
33
-
-
0032827427
-
Distribution of adjuvant MF59 and antigen gD2 after intramuscular injection in mice
-
Dupuis, M., McDonald, D. M. & Ott, G. Distribution of adjuvant MF59 and antigen gD2 after intramuscular injection in mice. Vaccine 18, 434-439 (1999).
-
(1999)
Vaccine
, vol.18
, pp. 434-439
-
-
Dupuis, M.1
McDonald, D.M.2
Ott, G.3
-
34
-
-
0032565591
-
Dendritic cells internalize vaccine adjuvant after intramuscular injection
-
Dupuis, M. et al. Dendritic cells internalize vaccine adjuvant after intramuscular injection. Cell. Immunol. 186, 18-27 (1998).
-
(1998)
Cell. Immunol.
, vol.186
, pp. 18-27
-
-
Dupuis, M.1
-
35
-
-
0011017020
-
Effect of immunological adjuvant combinations on the antibody and T-cell response to vaccination with MUC1-KLH and GD3-KLH conjugates
-
Kim, S-K., Ragupathi, G., Cappello, S., Kagan, E. & Livingston, P. O. Effect of immunological adjuvant combinations on the antibody and T-cell response to vaccination with MUC1-KLH and GD3-KLH conjugates. Vaccine 19, 530-537 (2000).
-
(2000)
Vaccine
, vol.19
, pp. 530-537
-
-
Kim, S.-K.1
Ragupathi, G.2
Cappello, S.3
Kagan, E.4
Livingston, P.O.5
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