Image-guided intrathymic injection of multipotent stem cells supports lifelong T-cell immunity and facilitates targeted immunotherapy

Blood

Volumn 123, Issue 18, 2014, Pages 2797-2805

  Tuckett, Andrea Z ^a   Thornton, Raymond H ^a   Shono, Yusuke ^a   Smith, Odette M ^a   Levy, Emily R ^a   Kreines, Fabiana M ^a   Van Den Brink, Marcel R M ^a   Zakrzewski, Johannes L ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RECOMBINANT INTERLEUKIN 7; RECOMBINANT KERATINOCYTE GROWTH FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW TRANSPLANTATION; CANCER IMMUNOTHERAPY; CANCER PATIENT; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL RENEWAL; CELL SELECTION; CELLULAR IMMUNITY; CONTROLLED STUDY; DRUG ADMINISTRATION ROUTE; FLOW CYTOMETRY; HEMATOPOIETIC STEM CELL; INTRATHYMIC ADMINISTRATION; LOW DRUG DOSE; MALE; MORBIDITY; MORTALITY; MOUSE; MULTIPOTENT STEM CELL; NONHUMAN; PRIORITY JOURNAL; RADIATION INJURY; RADIATION PROTECTION; SINGLE DRUG DOSE; UPREGULATION; WHOLE BODY RADIATION;

AGE FACTORS; ANIMALS; ANTIGENS; BONE MARROW TRANSPLANTATION; DISEASE MODELS, ANIMAL; FEMALE; HEMATOPOIETIC STEM CELLS; IMMUNITY, CELLULAR; IMMUNOPHENOTYPING; IMMUNOTHERAPY; LYMPHOPOIESIS; MICE; MULTIPOTENT STEM CELLS; NEOPLASMS; PHENOTYPE; RECEPTORS, ANTIGEN, T-CELL; STEM CELL TRANSPLANTATION; T-LYMPHOCYTES; THYMUS GLAND; WHOLE-BODY IRRADIATION;

EID: 84903170608     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2013-10-535401     Document Type: Article

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