메뉴 건너뛰기




Volumn 9, Issue 6, 2014, Pages

Depletion of the aryl hydrocarbon receptor in MDA-MB-231 human breast cancer cells altered the expression of genes in key regulatory pathways of cancer

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC HYDROCARBON RECEPTOR; CALVASCULIN; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 1; MUCIN 1; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 3; PROTEIN BCL 3; TRYPTOPHAN; VASCULOTROPIN A; MESSENGER RNA; SMALL INTERFERING RNA; TUMOR MARKER;

EID: 84903169173     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0100103     Document Type: Article
Times cited : (30)

References (36)
  • 1
    • 0020010617 scopus 로고
    • 2,3,7,8-tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons: Examination of the mechanism of toxicity
    • Poland A, Knutson JC (1982) 2,3,7,8-tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons: examination of the mechanism of toxicity. Annu Rev Pharmacol Toxicol 22: 517-554.
    • (1982) Annu Rev Pharmacol Toxicol , vol.22 , pp. 517-554
    • Poland, A.1    Knutson, J.C.2
  • 2
    • 0027458138 scopus 로고
    • The AH-receptor: Genetics, structure and function
    • DOI 10.1097/00008571-199310000-00001
    • Swanson HI, Bradfield CA (1993) The AH-receptor: genetics, structure and function. Pharmacogenetics 3: 213-230. (Pubitemid 23333091)
    • (1993) Pharmacogenetics , vol.3 , Issue.5 , pp. 213-230
    • Swanson, H.I.1    Bradfield, C.A.2
  • 3
    • 84868140854 scopus 로고    scopus 로고
    • The role of aryl hydrocarbon receptor and crosstalk with estrogen receptor in response of breast cancer cells to the novel antitumor agents benzothiazoles and aminoflavone
    • Callero MA, Loaiza-Perez AI (2011) The role of aryl hydrocarbon receptor and crosstalk with estrogen receptor in response of breast cancer cells to the novel antitumor agents benzothiazoles and aminoflavone. Int J Breast Cancer 2011: 923250.
    • (2011) Int J Breast Cancer , vol.2011 , pp. 923250
    • Callero, M.A.1    Loaiza-Perez, A.I.2
  • 4
    • 0030859287 scopus 로고    scopus 로고
    • A nuclear localization signal of human aryl hydrocarbon receptor nuclear translocator/hypoxia-inducible factor 1beta is a novel bipartite type recognized by the two components of nuclear pore-targeting complex
    • DOI 10.1074/jbc.272.28.17640
    • Eguchi H, Ikuta T, Tachibana T, Yoneda Y, Kawajiri K (1997) A nuclear localization signal of human aryl hydrocarbon receptor nuclear translocator/hypoxia-inducible factor 1beta is a novel bipartite type recognized by the two components of nuclear pore-targeting complex. J Biol Chem 272: 17640-17647. (Pubitemid 27311200)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.28 , pp. 17640-17647
    • Eguchi, H.1    Ikuta, T.2    Tachibana, T.3    Yoneda, Y.4    Kawajiri, K.5
  • 5
    • 36048964630 scopus 로고    scopus 로고
    • Identification of intracellular localization signals and of mechanisms underlining the nucleocytoplasmic shuttling of human aryl hydrocarbon receptor repressor
    • DOI 10.1016/j.bbrc.2007.10.140, PII S0006291X07022991
    • Kanno Y, Miyama Y, Takane Y, Nakahama T, Inouye Y (2007) Identification of intracellular localization signals and of mechanisms underlining the nucleocytoplasmic shuttling of human aryl hydrocarbon receptor repressor. Biochem Biophys Res Commun 364: 1026-1031. (Pubitemid 350087903)
    • (2007) Biochemical and Biophysical Research Communications , vol.364 , Issue.4 , pp. 1026-1031
    • Kanno, Y.1    Miyama, Y.2    Takane, Y.3    Nakahama, T.4    Inouye, Y.5
  • 6
    • 2642510760 scopus 로고    scopus 로고
    • Role of aryl hydrocarbon receptor-mediated induction of the CYP1 enzymes in environmental toxicity and cancer
    • DOI 10.1074/jbc.R400004200
    • Nebert DW, Dalton TP, Okey AB, Gonzalez FJ (2004) Role of aryl hydrocarbon receptor-mediated induction of the CYP1 enzymes in environmental toxicity and cancer. J Biol Chem 279: 23847-23850. (Pubitemid 38725238)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.23 , pp. 23847-23850
    • Nebert, D.W.1    Dalton, T.P.2    Okey, A.B.3    Gonzalez, F.J.4
  • 8
    • 68249149633 scopus 로고    scopus 로고
    • Characterization of MCF mammary epithelial cells overexpressing the Arylhydrocarbon receptor (AhR)
    • Wong PS, Li W, Vogel CF, Matsumura F (2009) Characterization of MCF mammary epithelial cells overexpressing the Arylhydrocarbon receptor (AhR). BMC Cancer 9: 234.
    • (2009) BMC Cancer , vol.9 , pp. 234
    • Wong, P.S.1    Li, W.2    Vogel, C.F.3    Matsumura, F.4
  • 9
    • 84885598942 scopus 로고    scopus 로고
    • Knockdown of aberrantly upregulated aryl hydrocarbon receptor reduces tumor growth and metastasis of MDA-MB-231 human breast cancer cell line
    • Goode GD, Ballard BR, Manning HC, Freeman ML, Kang Y, et al. (2013) Knockdown of aberrantly upregulated aryl hydrocarbon receptor reduces tumor growth and metastasis of MDA-MB-231 human breast cancer cell line. Int J Cancer 133: 2769-2780.
    • (2013) Int J Cancer , vol.133 , pp. 2769-2780
    • Goode, G.D.1    Ballard, B.R.2    Manning, H.C.3    Freeman, M.L.4    Kang, Y.5
  • 10
    • 3142689710 scopus 로고    scopus 로고
    • A constitutively active dioxin/aryl hydrocarbon receptor promotes hepatocarcinogenesis in mice
    • DOI 10.1158/0008-5472.CAN-03-0875
    • Moennikes O, Loeppen S, Buchmann A, Andersson P, Ittrich C, et al. (2004) A constitutively active dioxin/aryl hydrocarbon receptor promotes hepatocarcinogenesis in mice. Cancer Res 64: 4707-4710. (Pubitemid 38924510)
    • (2004) Cancer Research , vol.64 , Issue.14 , pp. 4707-4710
    • Moennikes, O.1    Loeppen, S.2    Buchmann, A.3    Andersson, P.4    Ittrich, C.5    Poellinger, L.6    Schwarz, M.7
  • 12
    • 33846554429 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor is over-expressed and constitutively activated in advanced breast carcinoma
    • Eltom SE, Gasmelseed A, Saoudi-Guentri D (2006) The aryl hydrocarbon receptor is over-expressed and constitutively activated in advanced breast carcinoma. Proc Amer Assoc Cancer Research 47.
    • (2006) Proc Amer Assoc Cancer Research , vol.47
    • Eltom, S.E.1    Gasmelseed, A.2    Saoudi-Guentri, D.3
  • 13
    • 79958093013 scopus 로고    scopus 로고
    • Malignant transformation of mammary epithelial cells by ectopic overexpression of the aryl hydrocarbon receptor
    • Brooks J, Eltom SE (2011) Malignant transformation of mammary epithelial cells by ectopic overexpression of the aryl hydrocarbon receptor. Curr Cancer Drug Targets 11: 654-669.
    • (2011) Curr Cancer Drug Targets , vol.11 , pp. 654-669
    • Brooks, J.1    Eltom, S.E.2
  • 14
    • 0142121516 scopus 로고    scopus 로고
    • Exploration, normalization, and summaries of high density oligonucleotide array probe level data
    • Irizarry RA, Hobbs B, Collin F, Beazer-Barclay YD, Antonellis KJ, et al. (2003) Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 4: 249-264.
    • (2003) Biostatistics , vol.4 , pp. 249-264
    • Irizarry, R.A.1    Hobbs, B.2    Collin, F.3    Beazer-Barclay, Y.D.4    Antonellis, K.J.5
  • 15
    • 23144464901 scopus 로고    scopus 로고
    • WebGestalt: An integrated system for exploring gene sets in various biological contexts
    • DOI 10.1093/nar/gki475
    • Zhang B, Kirov S, Snoddy J (2005) WebGestalt: an integrated system for exploring gene sets in various biological contexts. Nucleic Acids Res 33: W741-748. (Pubitemid 44530021)
    • (2005) Nucleic Acids Research , vol.33 , Issue.WEB. SERV. ISS.
    • Zhang, B.1    Kirov, S.2    Snoddy, J.3
  • 16
    • 58049196842 scopus 로고    scopus 로고
    • Integrating and annotating the interactome using the MiMI plugin for cytoscape
    • Gao J, Ade AS, Tarcea VG, Weymouth TE, Mirel BR, et al. (2009) Integrating and annotating the interactome using the MiMI plugin for cytoscape. Bioinformatics 25: 137-138.
    • (2009) Bioinformatics , vol.25 , pp. 137-138
    • Gao, J.1    Ade, A.S.2    Tarcea, V.G.3    Weymouth, T.E.4    Mirel, B.R.5
  • 17
    • 33751181032 scopus 로고    scopus 로고
    • Calpain mediates the dioxin-induced activation and down-regulation of the aryl hydrocarbon receptor
    • Dale YR, Eltom SE (2006) Calpain mediates the dioxin-induced activation and down-regulation of the aryl hydrocarbon receptor. Mol Pharmacol 70: 1481-1487.
    • (2006) Mol Pharmacol , vol.70 , pp. 1481-1487
    • Dale, Y.R.1    Eltom, S.E.2
  • 18
    • 80054041992 scopus 로고    scopus 로고
    • An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor
    • Opitz CA, Litzenburger UM, Sahm F, Ott M, Tritschler I, et al. (2011) An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor. Nature 478: 197-203.
    • (2011) Nature , vol.478 , pp. 197-203
    • Opitz, C.A.1    Litzenburger, U.M.2    Sahm, F.3    Ott, M.4    Tritschler, I.5
  • 19
    • 84862603083 scopus 로고    scopus 로고
    • Kynurenines in the mammalian brain: When physiology meets pathology
    • Schwarcz R, Bruno JP, Muchowski PJ, Wu HQ (2012) Kynurenines in the mammalian brain: when physiology meets pathology. Nat Rev Neurosci 13: 465-477.
    • (2012) Nat Rev Neurosci , vol.13 , pp. 465-477
    • Schwarcz, R.1    Bruno, J.P.2    Muchowski, P.J.3    Wu, H.Q.4
  • 20
    • 0942276780 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase/extracellular signal-regulated kinase attenuates 3-hydroxykynurenine-induced neuronal cell death
    • DOI 10.1111/j.1471-4159.2004.02191.x
    • Lee HJ, Bach JH, Chae HS, Lee SH, Joo WS, et al. (2004) Mitogen-activated protein kinase/extracellular signal-regulated kinase attenuates 3-hydroxykynurenine-induced neuronal cell death. J Neurochem 88: 647-656. (Pubitemid 38140209)
    • (2004) Journal of Neurochemistry , vol.88 , Issue.3 , pp. 647-656
    • Lee, H.J.1    Bach, J.-H.2    Chae, H.-S.3    Lee, S.H.4    Joo, W.S.5    Choi, S.H.6    Kim, K.Y.7    Lee, W.B.8    Kim, S.S.9
  • 21
    • 33745942997 scopus 로고    scopus 로고
    • MUC1 alters oncogenic events and transcription in human breast cancer cells
    • Hattrup CL, Gendler SJ (2006) MUC1 alters oncogenic events and transcription in human breast cancer cells. Breast Cancer Res 8: R37.
    • (2006) Breast Cancer Res , vol.8
    • Hattrup, C.L.1    Gendler, S.J.2
  • 23
    • 0034849755 scopus 로고    scopus 로고
    • Interleukin-8 and human cancer biology
    • Xie K (2001) Interleukin-8 and human cancer biology. Cytokine Growth Factor Rev 12: 375-391.
    • (2001) Cytokine Growth Factor Rev , vol.12 , pp. 375-391
    • Xie, K.1
  • 24
    • 65549143221 scopus 로고    scopus 로고
    • MMP13, Birc2 (cIAP1), and Birc3 (cIAP2), amplified on chromosome 9, collaborate with p53 deficiency in mouse osteosarcoma progression
    • Ma O, Cai WW, Zender L, Dayaram T, Shen J, et al. (2009) MMP13, Birc2 (cIAP1), and Birc3 (cIAP2), amplified on chromosome 9, collaborate with p53 deficiency in mouse osteosarcoma progression. Cancer Res 69: 2559-2567.
    • (2009) Cancer Res , vol.69 , pp. 2559-2567
    • Ma, O.1    Cai, W.W.2    Zender, L.3    Dayaram, T.4    Shen, J.5
  • 25
    • 0346996812 scopus 로고    scopus 로고
    • Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) Promotes Mitochondrial Dysfunction and Apoptosis Induced by 7-Hydroxystaurosporine and Mitogen-Activated Protein Kinase Kinase Inhibitors in Human Leukemia Cells That Ectopically Express Bcl-2 and Bcl-xL
    • DOI 10.1124/mol.64.6.1402
    • Dai Y, Dent P, Grant S (2003) Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) promotes mitochondrial dysfunction and apoptosis induced by 7-hydroxystaurosporine and mitogen-activated protein kinase kinase inhibitors in human leukemia cells that ectopically express Bcl-2 and Bcl-xL. Mol Pharmacol 64: 1402-1409. (Pubitemid 37532230)
    • (2003) Molecular Pharmacology , vol.64 , Issue.6 , pp. 1402-1409
    • Dai, Y.1    Dent, P.2    Grant, S.3
  • 26
    • 0034708132 scopus 로고    scopus 로고
    • Selective activation of NF-kappaB subunits in human breast cancer: Potential roles for NF-kappaB2/p52 and for Bcl-3
    • Cogswell PC, Guttridge DC, Funkhouser WK, Baldwin AS, Jr. (2000) Selective activation of NF-kappa B subunits in human breast cancer: potential roles for NF-kappa B2/p52 and for Bcl-3. Oncogene 19: 1123-1131. (Pubitemid 30157541)
    • (2000) Oncogene , vol.19 , Issue.9 , pp. 1123-1131
    • Cogswell, P.C.1    Guttridge, D.C.2    Funkhouser, W.K.3    Baldwin Jr., A.S.4
  • 27
    • 84863565481 scopus 로고    scopus 로고
    • Amplification and overexpression of the ABCC3 (MRP3) gene in primary breast cancer
    • Partanen L, Staaf J, Tanner M, Tuominen VJ, Borg A, et al. (2012) Amplification and overexpression of the ABCC3 (MRP3) gene in primary breast cancer. Genes Chromosomes Cancer 51: 832-840.
    • (2012) Genes Chromosomes Cancer , vol.51 , pp. 832-840
    • Partanen, L.1    Staaf, J.2    Tanner, M.3    Tuominen, V.J.4    Borg, A.5
  • 28
    • 48549095270 scopus 로고    scopus 로고
    • Functional genomics identifies ABCC3 as a mediator of taxane resistance in HER2-amplified breast cancer
    • O'Brien C, Cavet G, Pandita A, Hu X, Haydu L, et al. (2008) Functional genomics identifies ABCC3 as a mediator of taxane resistance in HER2-amplified breast cancer. Cancer Res 68: 5380-5389.
    • (2008) Cancer Res , vol.68 , pp. 5380-5389
    • O'Brien, C.1    Cavet, G.2    Pandita, A.3    Hu, X.4    Haydu, L.5
  • 29
    • 0344198168 scopus 로고    scopus 로고
    • Mts1 Regulates the Assembly of Nonmuscle Myosin-IIA
    • DOI 10.1021/bi0354379
    • Li ZH, Spektor A, Varlamova O, Bresnick AR (2003) Mts1 regulates the assembly of nonmuscle myosin-IIA. Biochemistry 42: 14258-14266. (Pubitemid 37499423)
    • (2003) Biochemistry , vol.42 , Issue.48 , pp. 14258-14266
    • Li, Z.-H.1    Spektor, A.2    Varlamova, O.3    Bresnick, A.R.4
  • 31
    • 0034618615 scopus 로고    scopus 로고
    • Isolation and characterization of a novel human gene (NESH) which encodes a putative signaling molecule similar to e3B1 protein
    • Miyazaki K, Matsuda S, Ichigotani Y, Takenouchi Y, Hayashi K, et al. (2000) Isolation and characterization of a novel human gene (NESH) which encodes a putative signaling molecule similar to e3B1 protein. Biochim Biophys Acta 1493: 237-241.
    • (2000) Biochim Biophys Acta , vol.1493 , pp. 237-241
    • Miyazaki, K.1    Matsuda, S.2    Ichigotani, Y.3    Takenouchi, Y.4    Hayashi, K.5
  • 36
    • 0842265105 scopus 로고    scopus 로고
    • p53 and VEGF expression are independent predictors of tumour recurrence and survival following curative resection of gastric cancer
    • DOI 10.1038/sj.bjc.6601455
    • Fondevila C, Metges JP, Fuster J, Grau JJ, Palacin A, et al. (2004) p53 and VEGF expression are independent predictors of tumour recurrence and survival following curative resection of gastric cancer. Br J Cancer 90: 206-215. (Pubitemid 38174963)
    • (2004) British Journal of Cancer , vol.90 , Issue.1 , pp. 206-215
    • Fondevila, C.1    Metges, J.P.2    Fuster, J.3    Grau, J.J.4    Palacin, A.5    Castells, A.6    Volant, A.7    Pera, M.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.