Adipose-derived regenerative cells in patients with ischemic cardiomyopathy: The PRECISE Trial

American Heart Journal

Volumn 168, Issue 1, 2014, Pages

  Perin, Emerson C ^a   Sanz Ruiz, Ricardo ^b   Sánchez, Pedro L ^b   Lasso, José ^b   Pérez Cano, Rosa ^b   Alonso Farto, Juan C ^b   Pérez David, Esther ^b   Fernández Santos, Maria Eugenia ^b   Serruys, Patrick W ^c   Duckers, Henrick J ^c   Kastrup, Jens ^d   Chamuleau, Steven ^e   Zheng, Yi ^a   Silva, Guilherme V ^a   Willerson, James T ^a   Fernández Avilés, Francisco ^b  

^a TEXAS HEART INSTITUTE   (United States)

^b HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑÓN   (Spain)

^c ERASMUS MEDICAL CENTER   (Netherlands)

^d Rigshospitalet   (Denmark)

^e UTRECHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOSE DERIVED STEM CELL; ADULT; AGED; ARTICLE; CARDIOVASCULAR MAGNETIC RESONANCE; CELL REGENERATION; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; ECHOCARDIOGRAPHY; FEMALE; FOLLOW UP; HEART LEFT VENTRICLE MASS; HUMAN; ISCHEMIC CARDIOMYOPATHY; LIPOSUCTION; MAJOR CLINICAL STUDY; MALE; METABOLIC EQUIVALENT; OXYGEN CONSUMPTION; PATIENT SAFETY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; STEM CELL TRANSPLANTATION; TREATMENT OUTCOME;

ADIPOCYTES; AGED; CELL TRANSPLANTATION; COLONY-FORMING UNITS ASSAY; DOUBLE-BLIND METHOD; ELECTROCARDIOGRAPHY; FEASIBILITY STUDIES; FEMALE; FOLLOW-UP STUDIES; HUMANS; INJECTIONS; MAGNETIC RESONANCE IMAGING, CINE; MALE; MIDDLE AGED; MYOCARDIAL ISCHEMIA; PROSPECTIVE STUDIES; TRANSPLANTATION, AUTOLOGOUS; TREATMENT OUTCOME;

EID: 84903142251     PISSN: 00028703     EISSN: 10976744     Source Type: Journal    
DOI: 10.1016/j.ahj.2014.03.022     Document Type: Article

References (36)

1. D.W. Losordo, R.A. Schatz, and C.J. White et al. Intramyocardial transplantation of autologous CD34+ stem cells for intractable angina: a phase I/IIa double-blind, randomized controlled trial Circulation 115 2007 3165 3172 (Pubitemid 47018140)
2. E.C. Perin, H.F. Dohmann, and R. Borojevic et al. Transendocardial, autologous bone marrow cell transplantation for severe, chronic ischemic heart failure Circulation 107 2003 2294 2302 (Pubitemid 36578498)
3. E.C. Perin, G.V. Silva, and T.D. Henry et al. A randomized study of transendocardial injection of autologous bone marrow mononuclear cells and cell function analysis in ischemic heart failure (FOCUS-HF) Am Heart J 161 2011 1078 1087 [e3]
4. H.F. Tse, S. Thambar, and Y.L. Kwong et al. Prospective randomized trial of direct endomyocardial implantation of bone marrow cells for treatment of severe coronary artery diseases (PROTECT-CAD trial) Eur Heart J 28 2007 2998 3005 (Pubitemid 350262782)
5. J. van Ramshorst, J.J. Bax, and S.L. Beeres et al. Intramyocardial bone marrow cell injection for chronic myocardial ischemia: a randomized controlled trial JAMA 301 2009 1997 2004
6. C. Toma, M.F. Pittenger, and K.S. Cahill et al. Human mesenchymal stem cells differentiate to a cardiomyocyte phenotype in the adult murine heart Circulation 105 2002 93 98 (Pubitemid 34049148)
7. J.M. Hare, J.E. Fishman, and G. Gerstenblith et al. Comparison of allogeneic vs autologous bone marrow-derived mesenchymal stem cells delivered by transendocardial injection in patients with ischemic cardiomyopathy: the POSEIDON randomized trial JAMA 308 2012 2369 2379
8. J.M. Hare, J.H. Traverse, and T.D. Henry et al. A randomized, double-blind, placebo-controlled, dose-escalation study of intravenous adult human mesenchymal stem cells (prochymal) after acute myocardial infarction J Am Coll Cardiol 54 2009 2277 2286
9. I.A. Panfilov, R. de Jong, and S. Takashima et al. Clinical study using adipose-derived mesenchymal-like stem cells in acute myocardial infarction and heart failure Methods Mol Biol 1036 2013 207 212
10. V. Planat-Benard, J.S. Silvestre, and B. Cousin et al. Plasticity of human adipose lineage cells toward endothelial cells: physiological and therapeutic perspectives Circulation 109 2004 656 663 (Pubitemid 38198874)
11. R. Sanz-Ruiz, E. Fernandez-Santos, and M. Dominguez-Munoa et al. Early translation of adipose-derived cell therapy for cardiovascular disease Cell Transplant 18 2009 245 254
12. D.A. De Ugarte, K. Morizono, and A. Elbarbary et al. Comparison of multi-lineage cells from human adipose tissue and bone marrow Cells Tissues Organs 174 2003 101 109 (Pubitemid 36819010)
13. J.K. Fraser, R. Schreiber, and B. Strem et al. Plasticity of human adipose stem cells toward endothelial cells and cardiomyocytes Nat Clin Pract Cardiovasc Med 3 Suppl. 1 2006 S33 S37
14. Y.S. Choi, G.J. Dusting, and S. Stubbs et al. Differentiation of human adipose-derived stem cells into beating cardiomyocytes J Cell Mol Med 14 2010 878 889
15. J. Rehman, D. Traktuev, and J. Li et al. Secretion of angiogenic and antiapoptotic factors by human adipose stromal cells Circulation 109 2004 1292 1298 (Pubitemid 38372789)
16. C. Valina, K. Pinkernell, and Y.H. Song et al. Intracoronary administration of autologous adipose tissue-derived stem cells improves left ventricular function, perfusion, and remodelling after acute myocardial infarction Eur Heart J 28 2007 2667 2677 (Pubitemid 350071533)
17. Y. Miyahara, N. Nagaya, and M. Kataoka et al. Monolayered mesenchymal stem cells repair scarred myocardium after myocardial infarction Nat Med 12 2006 459 465
18. M. Mazo, V. Planat-Benard, and G. Abizanda et al. Transplantation of adipose derived stromal cells is associated with functional improvement in a rat model of chronic myocardial infarction Eur J Heart Fail 10 2008 454 462
19. E.K. Shevchenko, P.I. Makarevich, and Z.I. Tsokolaeva et al. Transplantation of modified human adipose derived stromal cells expressing VEGF165 results in more efficient angiogenic response in ischemic skeletal muscle J Transl Med 11 2013 138
20. W.E. Wang, D. Yang, and L. Li et al. Prolyl hydroxylase domain protein 2 silencing enhances the survival and paracrine function of transplanted adipose-derived stem cells in infarcted myocardium Circ Res 113 2013 288 300
21. E.C. Perin, G.V. Silva, and R. Sarmento-Leite et al. Assessing myocardial viability and infarct transmurality with left ventricular electromechanical mapping in patients with stable coronary artery disease: validation by delayed-enhancement magnetic resonance imaging Circulation 106 2002 957 961 (Pubitemid 34925330)
22. M.J. Varma, R.G. Breuls, and T.E. Schouten et al. Phenotypical and functional characterization of freshly isolated adipose tissue-derived stem cells Stem Cells Dev 16 2007 91 104 (Pubitemid 46362594)
23. G. Astori, F. Vignati, and S. Bardelli et al. "In vitro" and multicolor phenotypic characterization of cell subpopulations identified in fresh human adipose tissue stromal vascular fraction and in the derived mesenchymal stem cells J Transl Med 5 2007 55
24. K. McIntosh, S. Zvonic, and S. Garrett et al. The immunogenicity of human adipose-derived cells: temporal changes in vitro Stem Cells 24 2006 1246 1253 (Pubitemid 44464693)
25. C. Dromard, P. Bourin, and M. Andre et al. Human adipose derived stroma/stem cells grow in serum-free medium as floating spheres Exp Cell Res 317 2011 770 780
26. T.D. Henry, D. Satran, and J.S. Hodges et al. Long-term survival in patients with refractory angina Eur Heart J 34 2013 2683 2688
27. D.M. Mancini, H. Eisen, and W. Kussmaul et al. Value of peak exercise oxygen consumption for optimal timing of cardiac transplantation in ambulatory patients with heart failure Circulation 83 1991 778 786
28. V.G. Florea, M.Y. Henein, and S.D. Anker et al. Prognostic value of changes over time in exercise capacity and echocardiographic measurements in patients with chronic heart failure Eur Heart J 21 2000 146 153 (Pubitemid 30072629)
29. M. Haack-Sorensen, T. Friis, and A.B. Mathiasen et al. Direct intramyocardial mesenchymal stromal cell injections in patients with severe refractory angina: one-year follow-up Cell Transplant 22 2013 521 528
30. R. Bolli, A.R. Chugh, and D. D'Amario et al. Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trial Lancet 378 2011 1847 1857
31. R.R. Makkar, R.R. Smith, and K. Cheng et al. Intracoronary cardiosphere-derived cells for heart regeneration after myocardial infarction (CADUCEUS): a prospective, randomised phase 1 trial Lancet 379 2012 895 904
32. D. Yang, W. Wang, and L. Li et al. The relative contribution of paracine effect versus direct differentiation on adipose-derived stem cell transplantation mediated cardiac repair PLoS One 8 2013 e59020
33. J. Myers, N. Buchanan, and D. Walsh et al. Comparison of the ramp versus standard exercise protocols J Am Coll Cardiol 17 1991 1334 1342
34. W.R. Thompson, N.F. Gordon, and L.S. Pescatello American College of Sports Medicine (ACSM): Guidelines for Exercise Testing and Prescription 8th ed. 2010 Williams and Wilkins Philadelphia: Lippincot
35. N.B. Schiller, P.M. Shah, and M. Crawford et al. Recommendations for quantitation of the left ventricle by two-dimensional echocardiography. American Society of Echocardiography Committee on Standards, Subcommittee on Quantitation of Two-Dimensional Echocardiograms J Am Soc Echocardiogr 2 1989 358 367
36. A.M. Beek, O. Bondarenko, and F. Afsharzada et al. Quantification of late gadolinium enhanced CMR in viability assessment in chronic ischemic heart disease: a comparison to functional outcome J Cardiovasc Magn Reson 11 2009 6