Improved chemical synthesis of hydrophobic Aβ peptides using addition of C-terminal lysines later removed by carboxypeptidase B

Biopolymers - Peptide Science Section

Volumn 102, Issue 2, 2014, Pages 206-221

  Chemuru, Saketh ^a   Kodali, Ravindra ^a   Wetzel, Ronald ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; GLYCOPROTEINS; HYDROPHOBICITY; PEPTIDES; PURIFICATION; CHROMATOGRAPHY; ENZYMES; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROPHOBIC CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; PROTEINS;

AMYLOID FORMATION; AMYLOIDOGENIC PEPTIDES; AMYLOIDOGENICITY; BENEFICIAL EFFECTS; CARBOXYPEPTIDASE; HYDROPHOBIC PEPTIDES; RECOMBINANT EXPRESSION; SOLID PHASE SYNTHESIS; AMYLOID; HYDROPHOBIC; IMMOBILIZED ENZYME; LYSINE; PURITY; RECOMBINANT; SOLID PHASE PEPTIDE SYNTHESIS; YIELD;

SYNTHESIS (CHEMICAL);

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; AMYLOID BETA PROTEIN[1-46]; CARBOXYPEPTIDASE B; IMMOBILIZED ENZYME; LYSINE; UNCLASSIFIED DRUG; CARBOXYPEPTIDASE A; CHYMOTRYPSIN; LYSINE DERIVATIVE; TRYPSIN; PROTEIN AGGREGATE;

AMINO ACID SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; HYDROPHOBICITY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PEPTIDE SYNTHESIS; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN PURIFICATION; PROTON NUCLEAR MAGNETIC RESONANCE; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SOLID PHASE SYNTHESIS; CONTROLLED STUDY; ENZYME IMMOBILIZATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ION EXCHANGE CHROMATOGRAPHY; CHEMICAL PHENOMENA; CHEMISTRY; ELECTROSPRAY MASS SPECTROMETRY; INFRARED SPECTROSCOPY; ISOLATION AND PURIFICATION; KINETICS; METABOLISM; MOLECULAR GENETICS; REVERSED PHASE LIQUID CHROMATOGRAPHY; SYNTHESIS; TEMPERATURE; ULTRASTRUCTURE;

AMINO ACID SEQUENCE; AMYLOID BETA-PEPTIDES; CARBOXYPEPTIDASE B; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, REVERSE-PHASE; ENZYMES, IMMOBILIZED; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; KINETICS; LYSINE; MOLECULAR SEQUENCE DATA; PROTEIN AGGREGATES; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TEMPERATURE;

EID: 84903138064     PISSN: 00063525     EISSN: 10970282     Source Type: Journal    
DOI: 10.1002/bip.22470     Document Type: Article

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