MHC-matched induced pluripotent stem cells can attenuate cellular and humoral immune responses but are still susceptible to innate immunity in pigs

PLoS ONE

Volumn 9, Issue 6, 2014, Pages

  Mizukami, Yoshihisa ^a   Abe, Tomoyuki ^a   Shibata, Hiroaki ^b   Makimura, Yukitoshi ^a   Fujishiro, Shuh Hei ^a   Yanase, Kimihide ^a   Hishikawa, Shuji ^a   Kobayashi, Eiji ^a   Hanazono, Yutaka ^a,c  

^a JICHI MEDICAL UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF BIOMEDICAL INNOVATION   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C1; LEUKOCYTE ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; SIALIC ACID DERIVATIVE; HLA ANTIGEN CLASS 2; SWINE LEUKOCYTE ANTIGEN;

ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; ATTENUATION; COMPLEMENT BLOOD LEVEL; CONTROLLED STUDY; CYTOTOXICITY ASSAY; EMBRYO; FEMALE; HUMAN; HUMORAL IMMUNITY; IMMUNOGENICITY; IN VITRO STUDY; IN VIVO STUDY; INCUBATION TIME; INNATE IMMUNITY; MALE; MINIPIG; MIXED LYMPHOCYTE REACTION; MOUSE; NATURAL KILLER CELL; NOD SCID MOUSE; NONHUMAN; PLURIPOTENT STEM CELL; T LYMPHOCYTE; TERATOMA; ANIMAL; AUTOTRANSPLANTATION; CELL CULTURE; IMMUNOLOGY; MAJOR HISTOCOMPATIBILITY COMPLEX; OVARY; PIG; SCID MOUSE; TESTIS; TRANSPLANTATION;

ANIMALS; CELLS, CULTURED; FEMALE; HISTOCOMPATIBILITY ANTIGENS CLASS II; IMMUNITY, HUMORAL; IMMUNITY, INNATE; INDUCED PLURIPOTENT STEM CELLS; KILLER CELLS, NATURAL; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; MICE; MICE, SCID; OVARY; SWINE; SWINE, MINIATURE; TERATOMA; TESTIS; TRANSPLANTATION, AUTOLOGOUS;

EID: 84903136134     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0098319     Document Type: Article

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