Instability of bacteriophages in spray-dried trehalose powders is caused by crystallization of the matrix

International Journal of Pharmaceutics

Volumn 472, Issue 1-2, 2014, Pages 202-205

  Vandenheuvel, Dieter ^a,b   Meeus, Joke ^b   Lavigne, Rob ^a   Van Den Mooter, Guy ^b  

^a LABORATORY OF GENE TECHNOLOGY   (Belgium)

^b DEPARTMENT OF PHARMACEUTICAL AND PHARMACOLOGICAL SCIENCES   (Belgium)

Author keywords

Bacteriophage; Crystallinity; Long term Storage; Spray drying; Trehalose

Indexed keywords

TREHALOSE; POWDER;

ARTICLE; BACTERIOPHAGE; CRYSTALLIZATION; DRUG STORAGE; GLASS TRANSITION TEMPERATURE; HIGH TEMPERATURE; HUMIDITY; LOW TEMPERATURE; POWDER; PRIORITY JOURNAL; SPRAY DRYING; STORAGE TEMPERATURE; THERMOSTABILITY; CHEMISTRY; DRUG FORMULATION; DRUG STABILITY; TEMPERATURE;

BACTERIOPHAGES; CRYSTALLIZATION; DRUG COMPOUNDING; DRUG STABILITY; DRUG STORAGE; HUMIDITY; POWDERS; TEMPERATURE; TREHALOSE;

EID: 84903124955     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.06.026     Document Type: Article

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