Misuse of the γ-aminobutyric acid analogues baclofen, gabapentin and pregabalin in the UK

British Journal of Clinical Pharmacology

Volumn 78, Issue 1, 2014, Pages 190-191

  Kapil, Vikas ^a,b,c   Green, Jody L ^d   Le Lait, Marie Claire ^d   Wood, David M ^a,e   Dargan, Paul I ^a,e  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^c BARTS HEALTH NHS TRUST   (United Kingdom)

^d ROCKY MOUNTAIN POISON AND DRUG CENTER   (United States)

^e KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BACLOFEN; GABAPENTIN; PREGABALIN; 4 AMINOBUTYRIC ACID; AMINE; CYCLOHEXANECARBOXYLIC ACID DERIVATIVE; STREET DRUG;

DRUG MISUSE; DRUG SURVEILLANCE PROGRAM; HARM REDUCTION; HUMAN; LETTER; NEUROPATHIC PAIN; PREVALENCE; PRIORITY JOURNAL; SELF REPORT; STRUCTURED INTERVIEW; TREATMENT OUTCOME; UNITED KINGDOM; ADOLESCENT; ADULT; ANALOGS AND DERIVATIVES; EPIDEMIOLOGY; FEMALE; GREAT BRITAIN; HEALTH SURVEY; MALE; MIDDLE AGED; STATISTICS AND NUMERICAL DATA; YOUNG ADULT;

ADOLESCENT; ADULT; AMINES; BACLOFEN; CYCLOHEXANECARBOXYLIC ACIDS; FEMALE; GAMMA-AMINOBUTYRIC ACID; GREAT BRITAIN; HEALTH SURVEYS; HUMANS; MALE; MIDDLE AGED; PREGABALIN; PRESCRIPTION DRUG MISUSE; STREET DRUGS; YOUNG ADULT;

EID: 84902978822     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/bcp.12277     Document Type: Letter

References (8)

1. National Institute for Health and Clinical Excellence. Neuropathic pain: the pharmacological management of neuropathic pain in adults in non- specialist settings. Available at http://www.nice.org.uk/guidance/CG96 (last accessed 1 August 2013).
2. Martinotti G,. Pregabalin in clinical psychiatry and addiction: pros and cons. Expert Opin Investig Drugs 2012; 21: 1243-1245.
3. NHS Prescription Services. Central nervous system national charts. Available at http://www.nhsbsa.nhs.uk/PrescriptionServices/Documents/ PPDPrescribingAnalysisCharts/CNS-National-April-2013.pdf (last accessed 1 August 2013).
4. European Monitoring Centre for Drugs and Drug Addiction (EMCDDA). 2010 Annual Report on the State of the Drugs Problem in Europe. Luxembourg: Publications Office of the European Union, 2010.
5. Schifano F, D'Offizi S, Piccione M, Corazza O, Deluca P, Davey Z, Di Melchiore G, Di Furia L, Farre M, Flesland L, Mannonen M, Majava A, Pagani S, Peltoniemi T, Siemann H, Skutle A, Torrens M, Pezzolesi C, van der Kreeft P, Scherbaum N,. Is there a recreational misuse potential for pregabalin? Analysis of anecdotal online reports in comparison with related gabapentin and clonazepam data. Psychother Psychom 2011; 80: 118-122.
6. Wood DM, Brailsford AD, Dargan PI,. Acute toxicity and withdrawal syndromes related to gamma-hydroxybutyrate (GHB) and its analogues gamma-butyrolactone (GBL) and 1,4-butanediol (1,4-BD). Drug Test Anal 2011; 3: 417-425.
7. LeTourneau JL, Hagg DS, Smith SM,. Baclofen and gamma-hydroxybutyrate withdrawal. Neurocrit Care 2008; 8: 430-433.
8. Home Office Statistics Unit/Office for National Statistics. Drug misuse declared: findings from the 2011/12 crime survey for England and Wales. Available at http://www.homeoffice.gov.uk/publications/science-research- statistics/research-statistics/crime-research/drugs-misuse-dec-1112 (last accessed 1 August 2013).