Supervisory control of a drop on demand mini-manufacturing system for pharmaceuticals

Computer Aided Chemical Engineering

Volumn 33, Issue , 2014, Pages 535-540

  Icten, Elcin ^a   Nagy, Zoltan K ^a   Reklaitis, Gintaras V ^a  

^a PURDUE UNIVERSITY   (United States)

Author keywords

Drug delivery; Polynomial chaos expansion; Process development; Supervisory control; Temperature control

Indexed keywords

EID: 84902953052     PISSN: 15707946     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-444-63456-6.50090-9     Document Type: Chapter

References (8)

1. Guidance for Industry Q8(R2) Pharmaceutical Development 2009, Food and Drug Administration, ICT, USA.
2. Fujiwara M., Nagy Z.K., Chew J.W., Braatz R.D. First-principles and direct design approaches for the control of pharmaceutical crystallization. Journal of Process Control 2005, 15(5):493-504.
3. Gernaey K.V., Cervera-Padrell A.E., Woodley J.M. A perspective on PSE in pharmaceutical process development and innovation. Computers and Chemical Engineering 2012, 42:15-29.
4. Hirshfield L., Giridhar A., Taylor L., Harris M., Reklaitis G.V. Dropwise Additive Manufacturing of Pharmaceutical Products for Solvent-based Dosage Forms. Journal of Pharmaceutical Sciences 2014, 103(2):496-506.
5. Hsu H., Toth S.J., Simpson G.J., Taylor L., Harris M. Effect of substrates on naproxen-polyvinylpyrrolidone solid dispersions formed via the drop printing technique. Journal of Pharmaceutical Sciences 2013, 102(2):638-648.
6. Laine J.M., Schaefer E., Reklaitis G.V. Challenges and opportunities in enterprise-wide optimization in the pharmaceutical industry. Computers and Chemical Engineering 2012, 47:19-28.
7. Nagy Z.K., Braatz R.D. Open-loop and closed-loop robust optimal control of batch processes using distributional and worst-case analysis. Journal of Process Control 2004, 14:411-422.
8. Trasi N.S., Taylor L.S. Effect of Additives on Crystal Growth and Nucleation of Amorphous Flutamide. Crystal Growth and Design 2012, 12-6:3221-3230.