Traditional Chinese Medicine (TCM) for fibrotic liver disease: Hope and hype

Journal of Hepatology

Volumn 61, Issue 1, 2014, Pages 166-168

  Zhang, Lijun ^a   Schuppan, Detlef ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Antifibrotic; Cirrhosis; Collagen; Fibrosis; HBV; HCV; Hepatitis; Herb; Inflammation; Liver; NASH; TCM

Indexed keywords

ALKALOID; FUZHENG HUAYU; HEAVY METAL; HERBACEOUS AGENT; UNCLASSIFIED DRUG;

ABDOMINAL SWELLING; ANIMAL SHELL; ARTICLE; CANCER THERAPY; CARAPAX TRIONYCIS; CHINA; CHINESE; CHINESE MEDICINE; CHRONIC LIVER DISEASE; CIVILIZATION; DRUG APPROVAL; DRUG EFFICACY; DRUG MARKETING; DRUG MECHANISM; DRUG QUALITY; DRUG REPOSITIONING; DRUG SAFETY; EMPIRICISM; EVIDENCE BASED MEDICINE; EXERCISE; FOOD AND DRUG ADMINISTRATION; GOVERNMENT; HEMOSTASIS; HEPATITIS B; HEPATITIS C; HISTORY; HUMAN; LIVER CELL CARCINOMA; LIVER CELL CULTURE; LIVER CIRRHOSIS; LIVER FIBROSIS; LIVER TOXICITY; MICROBIOME; NEPHROTOXICITY; NONHUMAN; NUTRITION; PHILOSOPHY OF MEDICINE; PRESCRIPTION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); SIGNAL TRANSDUCTION; SKIN DISCOLORATION; TURTLE; UPPER ABDOMINAL PAIN; CLINICAL TRIAL (TOPIC); PHILOSOPHY;

CLINICAL TRIALS AS TOPIC; DRUGS, CHINESE HERBAL; HOLISTIC HEALTH; HUMANS; LIVER CIRRHOSIS; MEDICINE, CHINESE TRADITIONAL;

EID: 84902674409     PISSN: 01688278     EISSN: 16000641     Source Type: Journal    
DOI: 10.1016/j.jhep.2014.03.009     Document Type: Note

References (12)

1. D. Schuppan, and Y.O. Kim Evolving therapies for liver fibrosis J Clin Invest 123 2013 1887 1901
2. S.L. Friedman, D. Sheppard, J.S. Duffield, and S. Violette Therapy for fibrotic diseases: nearing the starting line Sci Transl Med 5 2013 167sr161
3. D. Schuppan, and M. Pinzani Anti-fibrotic therapy: lost in translation? J Hepatol 56 2012 S66 S74
4. C.H. Liu, P. Liu, Y.Y. Hu, L.M. Xu, and C. Liu Progress of clinical and basic research on liver fibrosis with Traditional Chinese Medicine World Sci Technol 9 2007 112 119
5. P. Liu Treatment of cirrhosis and liver fibrosis by traditional Chinese medicine Chin Hepatol 7 2002 33 35
6. J.M. Luk, X. Wang, P. Liu, K.F. Wong, K.L. Chan, and Y. Tong et al. Traditional Chinese herbal medicines for treatment of liver fibrosis and cancer: from laboratory discovery to clinical evaluation Liver Int 27 2007 879 890
7. D. Schuppan, J.D. Jia, B. Brinkhaus, and E.G. Hahn Herbal products for liver diseases: a therapeutic challenge for the new millennium Hepatology 30 1999 1099 1104
8. S.S. Yin, B.E. Wang, T.L. Wang, J.D. Jia, and L.X. Qian The effect of Cpd 861 on chronic hepatitis B related fibrosis and early cirrhosis: a randomized, double blind, placebo controlled clinical trial Zhonghua Gan Zang Bing Za Zhi 12 2004 467 470
9. S.G. Guo, W. Zhang, T. Jiang, M. Dai, L.F. Zhang, and Y.C. Meng et al. Influence of serum collected from rat perfused with compound Biejiaruangan drug on hepatic stellate cells World J Gastroenterol 10 2004 1487 1494
10. P. Liu, Y.Y. Hu, C. Liu, L.M. Xu, C.H. Liu, and K.W. Sun et al. Multicenter clinical study on Fuzhenghuayu capsule against liver fibrosis due to chronic hepatitis B World J Gastroenterol 11 2005 2892 2899
11. Liu Zhihua. One step closer for US to recognize TCM. China daily [Internet] 2013 Nov 27 [cited 2014 Jan 10]. Available from: http://www. chinadaily.com.cn/culture/2013-11/27/content-17133333.htm.
12. D. Schuppan, and J.M. Schattenberg Non-alcoholic steatohepatitis: pathogenesis and novel therapeutic approaches J Gastroenterol Hepatol 28 2013 68 76