Exploitation of lectinized lipo-polymerosome encapsulated amphotericin b to target macrophages for effective chemotherapy of visceral leishmaniasis

Bioconjugate Chemistry

Volumn 25, Issue 6, 2014, Pages 1091-1102

  Gupta, Pramod K ^a   Asthana, Shalini ^a   Jaiswal, Anil K ^a   Kumar, Vivek ^a   Verma, Ashwni K ^a   Shukla, Prashant ^a   Dwivedi, Pankaj ^a   Dube, Anuradha ^a   Mishra, Prabhat R ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOTHERAPY; PROTEINS;

AMBISOME; AMPHOTERICIN B; CARBODIIMIDE COUPLINGS; EFFECTIVE MANAGEMENT; FUNCTIONALIZED; GLYCOL CHITOSAN; LEC; LECTIN RECEPTORS; PARASITE-; VISCERAL LEISHMANIASIS;

MACROPHAGES;

ALANINE AMINOTRANSFERASE; AMPHOTERICIN B; AMPHOTERICIN B DEOXYCHOLATE; AMPHOTERICIN B LIPID COMPLEX; ASPARTATE AMINOTRANSFERASE; CHITOSAN; CHOLESTEROL; COPOLYMER; CREATININE; CYANAMIDE; GLYCOL; INDUCIBLE NITRIC OXIDE SYNTHASE; LECTIN; LECTIN RECEPTOR; LIPOPOLYMEROSOME; NANOPARTICLE; NITRIC OXIDE; STEARIC ACID; UNCLASSIFIED DRUG; UREA; ANTIPROTOZOAL AGENT; LIPOSOME; POLYMER;

AMASTIGOTE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BINDING SITE; BLOOD SAMPLING; CHEMOTHERAPY; CONTROLLED STUDY; CREATININE BLOOD LEVEL; CYTOTOXICITY; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; ENCAPSULATION; HEMOLYSIS; HUMAN; HUMAN CELL; INFRARED SPECTROSCOPY; LIPID MONOLAYER; MACROPHAGE; MEAN RESIDENCE TIME; MORPHOLOGICAL TRAIT; MOUSE; NEPHROTOXICITY; NONHUMAN; ORGAN DISTRIBUTION; PARTICLE SIZE; PROTON NUCLEAR MAGNETIC RESONANCE; SURFACE PROPERTY; SUSTAINED DRUG RELEASE; TISSUE DISTRIBUTION; UREA BLOOD LEVEL; VISCERAL LEISHMANIASIS; ZETA POTENTIAL; ANIMAL; CELL CULTURE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; DRUG SENSITIVITY; HAMSTER; LEISHMANIA DONOVANI; LEISHMANIASIS, VISCERAL; MALE; PARASITOLOGY; RAT; WISTAR RAT;

AMPHOTERICIN B; ANIMALS; ANTIPROTOZOAL AGENTS; CELLS, CULTURED; CRICETINAE; LECTINS; LEISHMANIA DONOVANI; LEISHMANIASIS, VISCERAL; LIPOSOMES; MACROPHAGES; MALE; MICE; MOLECULAR STRUCTURE; PARASITIC SENSITIVITY TESTS; POLYMERS; RATS; RATS, WISTAR; TISSUE DISTRIBUTION;

EID: 84902659755     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/bc500087h     Document Type: Article

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