Crucial role of Plexin C1 for pulmonary inflammation and survival during lung injury

Mucosal Immunology

Volumn 7, Issue 4, 2014, Pages 879-891

  Granja, T ^a   Kohler D ^a   Mirakaj, V ^a   Nelson, E ^b   Konig K ^a   Rosenberger, P ^a  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PLEXIN; PLEXIN C1; UNCLASSIFIED DRUG; CELL SURFACE RECEPTOR; CYTOKINE; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; LEUKOCYTE ANTIGEN; NERVE PROTEIN; PLXNA3 PROTEIN, MOUSE; SEMA7A PROTEIN, HUMAN; SEMAPHORIN;

5' UNTRANSLATED REGION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING SITE; CONTROLLED STUDY; LUNG INJURY; LUNG VENTILATION; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PNEUMONIA; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; SURVIVAL; SURVIVAL TIME; ACUTE LUNG INJURY; ANIMAL; BIOLOGICAL MODEL; CHEMISTRY; DISEASE MODEL; GENE EXPRESSION; GENETICS; HUMAN; IMMUNOLOGY; KNOCKOUT MOUSE; LUNG ALVEOLUS; METABOLISM; MORTALITY; NEUTROPHIL; PATHOLOGY;

ACUTE LUNG INJURY; ANIMALS; ANTIGENS, CD; CHEMOTAXIS, LEUKOCYTE; CYTOKINES; DISEASE MODELS, ANIMAL; GENE EXPRESSION; GPI-LINKED PROTEINS; HUMANS; MICE; MICE, KNOCKOUT; MODELS, BIOLOGICAL; NERVE TISSUE PROTEINS; NEUTROPHILS; PNEUMONIA; PULMONARY ALVEOLI; RECEPTORS, CELL SURFACE; SEMAPHORINS;

EID: 84902597841     PISSN: 19330219     EISSN: 19353456     Source Type: Journal    
DOI: 10.1038/mi.2013.104     Document Type: Article

References (27)

1. Rubenfeld, G.D., Caldwell, E., Peabody, E., Weaver, J., Martin, D.P. & Neff, M. et al. Incidence and outcomes of acute lung injury. N. Engl. J.Med. 353, 1685-1693 (2005
2. Ware, L.B. & Matthay, M.A. The acute respiratory distress syndrome. N. Engl. J. Med. 342, 1334-1349 (2000
3. Charo, I.F. & Ransohoff, R.M. The many roles of chemokines and chemokine receptors in inflammation. N. Engl. J. Med. 354, 610-621 (2006
4. Luster, A.D. Chemokines-chemotactic cytokines that mediate inflammation. N. Engl. J. Med. 338, 436-445 (1998
5. Mirakaj, V., Gatidou, D., Potzsch, C., Konig, K. & Rosenberger, P. Netrin-1 signaling dampens inflammatory peritonitis. J. Immunol. 186, 549-555 (2011
6. Mirakaj, V., Thix, C.A., Laucher, S., Mielke, C., Morote-Garcia, J.C. & Schmit, M.A. et al. Netrin-1 dampens pulmonary inflammation During acute lung injury. Am. J. Respir. Crit. Care Med. 181, 815-824 (2010
7. Rosenberger, P., Schwab, J.M., Mirakaj, V., Masekowsky, E., Mager, A. & Morote-Garcia, J.C. et al. Hypoxia-inducible factor-dependent induction of netrin-1 dampens inflammation caused by hypoxia. Nat. Immunol. 10, 195-202 (2009
8. Morote-Garcia, J.C., Napiwotzky, D., Kohler, D. & Rosenberger, P. Endothelial Semaphorin 7A promotes neutrophilmigration During hypoxia. Proc. Natl Acad. Sci. USA 109, 14146-14151 (2012
9. Ohta, K., Mizutani, A., Kawakami, A., Murakami, Y., Kasuya, Y. & Takagi, S. et al. Plexin: A novel neuronal cell surface molecule that mediates cell adhesion via a homophilic binding mechanism in the presence of calcium ions. Neuron 14, 1189-1199 (1995
10. Takagi, S., Tsuji, T., Amagai, T., Takamatsu, T. & Fujisawa, H. Specific cell surface labels in the visual centers of Xenopus laevis tadpole identified using monoclonal antibodies. Dev. Biol. 122, 90-100 (1987
11. Comeau, M.R., Johnson, R., DuBose, R.F., Petersen, M., Gearing, P. & VandenBos, T. et al. A poxvirus-encoded semaphorin induces cytokine production from monocytes and binds to a novel cellular semaphorin receptor, VESPR. Immunity 8, 473-482 (1998
12. Tamagnone, L., Artigiani, S., Chen, H., He, Z., Ming, G.I. & Song, H. et al. Plexins are a large family of receptors for transmembrane, secreted, and GPI-Anchored semaphorins in vertebrates. Cell 99, 71-80 (1999
13. Liu, H., Juo, Z.S., Shim, A.H., Focia, P.J.,Chen, X. &Garcia, K.C. et al. Structural basis of semaphorin-plexin recognition and viral mimicry from Sema7A and A39R complexes with PlexinC1. Cell 142, 749-761 (2010
14. Holmes, S., Downs, A.M., Fosberry, A., Hayes, P.D., Michalovich, D. & Murdoch, P. et al. Sema7A is a potent monocyte stimulator. Scand. J Immunol. 56, 270-275 (2002
15. Walzer, T., Galibert, L., Comeau, M.R. & De Smedt, T. Plexin C1 engagement on mouse dendritic cells by viral semaphorin A39R induces actin cytoskeleton rearrangement and inhibits integrin-mediated adhesion and chemokine-induced migration. J. Immunol. 174, 51-59 (2005
16. Lewandrowski, U.,Wortelkamp, S., Lohrig, K., Zahedi, R.P., Wolters, D.A. & Walter, U. et al. Platelet membrane proteomics: A novel repository for functional research. Blood 114, e10-e19 (2009
17. Walzer, T., Galibert, L. & De Smedt, T. Dendritic cell function inmice lacking Plexin C1. Int. Immunol. 17, 943-950 (2005
18. Derijck, A.A., Van Erp, S. & Pasterkamp, R.J. Semaphorin signaling: Molecular switches at the midline. Trends Cell Biol. 20, 568-576 (2010
19. Chabbert-de Ponnat, I., Marie-Cardine, A., Pasterkamp, R.J., Schiavon, V., Tamagnone, L. & Thomasset, N. et al. Soluble CD100 functions on human monocytes and immature dendritic cells require plexin C1 and plexin B1, respectively. Int. Immunol. 17, 439-447 (2005
20. Walzer, T., Galibert, L. & De Smedt, T. Poxvirus semaphorin A39R inhibits phagocytosis by dendritic cells and neutrophils. Eur. J. Immunol. 35, 391-398 (2005
21. Kang, S.,Okuno, T., Takegahara,N., Takamatsu, H.,Nojima, S. & Kimura, T. et al. Intestinal epithelial cell-derived semaphorin 7A negatively regulates development of colitis via alphavbeta1 integrin. J. Immunol. 188, 1108-1116 (2012
22. Brown, K.A., Brain, S.D., Pearson, J.D., Edgeworth, J.D., Lewis, S.M. & Treacher, D.F. Neutrophils in Development of multiple organ failure in sepsis. Lancet 368, 157-169 (2006
23. Lazova, R., Gould Rothberg, B.E., Rimm, D. & Scott, G. The semaphorin 7A receptor Plexin C1 is lost during melanoma metastasis. Am. J. Dermatopathol. 31, 177-181 (2009
24. Pasterkamp, R.J., Peschon, J.J., Spriggs, M.K. & Kolodkin, A.L. Semaphorin 7A promotes axon outgrowth through integrins and MAPKs. Nature 424, 398-405 (2003
25. Suzuki, K., Okuno, T., Yamamoto, M., Pasterkamp, R.J., Takegahara, N. & Takamatsu, H. et al. Semaphorin 7A initiates T-cell-mediated inflammatory responses through alpha1beta1 integrin. Nature 446, 680-684 (2007
26. Eckle, T., Brodsky, K., Bonney, M., Packard, T., Han, J. & Borchers, C.H. et al. HIF1A reduces acute lung injury by optimizing carbohydrate metabolism in the alveolar epithelium. PLoS Biol. 11, e1001665 (2013
27. Eltzschig, H.K. & Carmeliet, P. Hypoxia and inflammation. N. Engl. J.Med. 364, 656-665 (2011.