Risk factors for carriage of AOM pathogens during the first 3 years of life in children with early onset of acute otitis media

Acta Oto-Laryngologica

Volumn 134, Issue 7, 2014, Pages 684-690

  Gisselsson Solén, Marie ^a   Henriksson, Gunnel ^a   Hermansson, Ann ^a   Melhus, Åsa ^b  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

Author keywords

Day care; Haemophilus influenzae; Moraxella catarrhalis; Nasopharyngeal carriage; Nasopharyngeal colonization; Otitis prone children; RAOM; Season; Streptococcus pneumoniae

Indexed keywords

ANTIBIOTIC AGENT; HEPTAVALENT PNEUMOCOCCAL CONJUGATE VACCINE; PNEUMOCOCCUS VACCINE;

ACUTE OTITIS MEDIA; ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL COUNT; BACTERIUM CARRIER; BACTERIUM CULTURE; CHILD; CHILDHOOD DISEASE; CONTROLLED STUDY; DAY CARE; FAMILY HISTORY; FEMALE; FOLLOW UP; HAEMOPHILUS INFLUENZAE; HUMAN; IMMUNOCOMPROMISED PATIENT; INFANT; MAJOR CLINICAL STUDY; MALE; MORAXELLA CATARRHALIS; NASOPHARYNGEAL CARRIAGE; PARENTAL SMOKING; PATHOGENESIS; PHYSICAL EXAMINATION; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; RECURRENT DISEASE; RISK FACTOR; STREPTOCOCCUS PNEUMONIAE; VACCINATION; ACUTE DISEASE; COHORT ANALYSIS; HETEROZYGOTE; ISOLATION AND PURIFICATION; MICROBIOLOGY; NASOPHARYNX; ONSET AGE; OTITIS MEDIA; PRESCHOOL CHILD; SINGLE BLIND PROCEDURE; STREPTOCOCCUS PYOGENES;

ACUTE DISEASE; AGE OF ONSET; CARRIER STATE; CHILD, PRESCHOOL; COHORT STUDIES; FEMALE; HAEMOPHILUS INFLUENZAE; HUMANS; INFANT; MALE; MORAXELLA (BRANHAMELLA) CATARRHALIS; NASOPHARYNX; OTITIS MEDIA; PNEUMOCOCCAL VACCINES; PROSPECTIVE STUDIES; RECURRENCE; RISK FACTORS; SINGLE-BLIND METHOD; STREPTOCOCCUS PNEUMONIAE; STREPTOCOCCUS PYOGENES;

EID: 84902589934     PISSN: 00016489     EISSN: 16512251     Source Type: Journal    
DOI: 10.3109/00016489.2014.890291     Document Type: Article

References (20)

1. Alho OP, Koivu M, Sorri M, Rantakallio P. The occurrence of acute otitis media in infants. A life-Table analysis. Int J Pediatr Otorhinolaryngol 1991;21:7-14
2. Kilpi T, Herva E, Kaijalainen T, Syrjanen R, Takala AK. Bacteriology of acute otitis media in a cohort of Finnish children followed for the first two years of life. Pediatr Infect Dis J 2001;20:654-62. (Pubitemid 32652315
3. Aniansson G, Alm B, Andersson B, Larsson P, Nylen O, Peterson H, et al. Nasopharyngeal colonization during the first year of life. J Infect Dis 1992;165:S38-42
4. Faden H, Waz MJ, Bernstein JM, Brodsky L, Stanievich J, Ogra PL. Nasopharyngeal flora in the first three years of life in normal and otitis-prone children. Ann Otol Rhinol Laryngol 1991;100:612-15
5. Ingvarsson L, Lundgren K, Ursing J. The bacterial flora in the nasopharynx in healthy children. Acta Otolaryngol Suppl 1982;386:94-6. (Pubitemid 13248474
6. Wiertsema SP, Kirkham LA, Corscadden KJ, Mowe EN, Bowman JM, Jacoby P, et al. Predominance of nontypeable Haemophilus influenzae in children with otitis media following introduction of a 3+0 pneumococcal conjugate vaccine schedule. Vaccine 2011;29:5163-70
7. Labout JA, Duijts L, Arends LR, Jaddoe VW, Hofman A, de Groot R, et al. Factors associated with pneumococcal carriage in healthy Dutch infants: The generation R study. J Pediatr 2008;153:771-6
8. van Gils EJ, Veenhoven RH, Rodenburg GD, Hak E, Sanders EA. Effect of 7-valent pneumococcal conjugate vaccine on nasopharyngeal carriage with Haemophilus influenzae and Moraxella catarrhalis in a randomized controlled trial. Vaccine 2011;29:7595-8
9. Bakaletz LO. Viral potentiation of bacterial superinfection of the respiratory tract. Trends Microbiol 1995;3:110-14
10. van den Bergh MR, Biesbroek G, Rossen JW, de Steenhuijsen Piters WA, Bosch AA, van Gils EJ, et al. Associations between pathogens in the upper respiratory tract of young children: Interplay between viruses and bacteria. PLoS One 2012;7:e47711
11. Harsten G, Prellner K, Heldrup J, Kalm O, Kornfalt R. Recurrent acute otitis media. A prospective study of children during the first three years of life. Acta Otolaryngol 1989;107; 111-19
12. STRAMA. Treatment for acute inflammation of the middle ear, Consensus Statement 2000. Available from http://en. strama.se/dyn//,87,14.html
13. Ruohola A, Pettigrew MM, Lindholm L, Jalava J, Raisanen KS, Vainionpaa R, et al. Bacterial and viral interactions within the nasopharynx contribute to the risk of acute otitis media. J Infect 2013;66:247-54
14. Principi N, Marchisio P, Schito GC, Mannelli S. Risk factors for carriage of respiratory pathogens in the nasopharynx of healthy children. Ascanius Project Collaborative Group. Pediatr Infect Dis J 1999;18:517-23. (Pubitemid 29277615
15. Marchisio P, Gironi S, Esposito S, Schito GC, Mannelli S, Principi N. Seasonal variations in nasopharyngeal carriage of respiratory pathogens in healthy Italian children attending day-care centres or schools. J Med Microbiol 2001;50:1095-9. (Pubitemid 33108917
16. Sabirov A, Casey JR, Murphy TF, Pichichero ME. Breastfeeding is associated with a reduced frequency of acute otitis media and high serum antibody levels against NTHi and outer membrane protein vaccine antigen candidate P6. Pediatr Res 2009;66:565-70
17. Greenberg D, Givon-Lavi N, Broides A, Blancovich I, Peled N, Dagan R. The contribution of smoking and exposure to tobacco smoke to Streptococcus pneumoniae and Haemophilus influenzae carriage in children and their mothers. Clin Infect Dis 2006;42:897-903
18. Pettigrew MM, Gent JF, Revai K, Patel JA, Chonmaitree T. Microbial interactions during upper respiratory tract infections. Emerg Infect Dis 2008;14:1584-91
19. Pericone CD, Overweg K, Hermans PW, Weiser JN. Inhibitory and bactericidal effects of hydrogen peroxide production by Streptococcus pneumoniae on other inhabitants of the upper respiratory tract. Infect Immun 2000;68:3990-7. (Pubitemid 30434551
20. Margolis E, Yates A, Levin BR. The ecology of nasal colonization of Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus: The role of competition and interactions with host's immune response. BMC Microbiol 2010;10:59.