The prognosis of N2b and N2c lymph node disease in oral squamous cell carcinoma is determined by the number of metastatic lymph nodes rather than laterality

Cancer

Volumn 120, Issue 13, 2014, Pages 1968-1974

  Ebrahimi, Ardalan ^a,b,c   Gil, Ziv ^d   Amit, Moran ^d   Yen, Tzu Chen ^e   Liao, Chun Ta ^e   Chaturvedi, Pankaj ^f   Agarwal, Jai Prakash ^f   Kowalski, Luiz P ^g   Kohler, Hugo F ^g   Kreppel, Matthias ^h   Cernea, Claudio R ⁱ   Brandao, Jose ⁱ   Bachar, Gideon ^j   Bolzoni Villaret, Andrea ^k   Fliss, Dan ^l   Fridman, Eran ^l   Robbins, K Thomas ^m   Shah, Jatin P ⁿ   Patel, Snehal G ⁿ   Clark, Jonathan R ^a  

^a ROYAL PRINCE ALFRED HOSPITAL   (Australia)

^b MACQUARIE UNIVERSITY   (Australia)

^c UNIVERSITY OF NEW SOUTH WALES   (Australia)

^d TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^e CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^f TATA MEMORIAL HOSPITAL   (India)

^g A C CAMARGO CANCER CENTER   (Brazil)

^h UNIVERSITY OF COLOGNE   (Germany)

ⁱ UNIVERSITY OF SÃO PAULO   (Brazil)

^j RABIN MEDICAL CENTER   (Israel)

^k UNIVERSITY OF BRESCIA   (Italy)

^l TEL AVIV SOURASKY MEDICAL CENTER   (Israel)

^m SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

ⁿ MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

more..

Author keywords

cancer staging; head and neck neoplasms; lymph node metastases; oral squamous cell carcinoma; prognosis

Indexed keywords

ADULT; AGED; ARTICLE; CANCER CLASSIFICATION; CANCER PROGNOSIS; CANCER STAGING; CANCER SURGERY; CANCER SURVIVAL; CONTROLLED STUDY; DISEASE FREE SURVIVAL; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LYMPH NODE METASTASIS; LYMPHADENOPATHY; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MOUTH SQUAMOUS CELL CARCINOMA; MULTICENTER STUDY; OVERALL SURVIVAL; PRIORITY JOURNAL; RETROSPECTIVE STUDY; VERY ELDERLY; YOUNG ADULT;

CANCER STAGING; HEAD AND NECK NEOPLASMS; LYMPH NODE METASTASES; ORAL SQUAMOUS CELL CARCINOMA; PROGNOSIS;

AGED; CARCINOMA, SQUAMOUS CELL; EVIDENCE-BASED MEDICINE; FEMALE; HUMANS; INTERNATIONAL COOPERATION; KAPLAN-MEIER ESTIMATE; LYMPH NODES; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; MOUTH NEOPLASMS; NECK DISSECTION; NEOPLASM STAGING; PREDICTIVE VALUE OF TESTS; PROGNOSIS; RETROSPECTIVE STUDIES; UNITED STATES;

EID: 84902550988     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.28686     Document Type: Article

References (13)

1. Edge SB, Byrd DR, Compton CC, Fritz AG, Greene FL, Trotti A, eds. AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer; 2010.
2. Groome PA, Schulze K, Boysen M, Hall SF, Mackillop WJ,. A comparison of published head and neck stage groupings in carcinomas of the oral cavity. Head Neck. 2001; 23: 613-624.
3. Manikantan K, Sayed SI, Syrigos KN, et al. Challenges for the future modifications of the TNM staging system for head and neck cancer: case for a new computational model&quest Cancer Treat Rev. 2009; 35: 639-644.
4. Hall SF, Groome PA, Irish J, O'Sullivan B,. TNM-based stage groupings in head and neck cancer: application in cancer of the hypopharynx. Head Neck. 2009; 31: 1-8.
5. Kreppel M, Drebber U, Rothamel D, et al. Prognostic impact of different TNM-based stage groupings for oral squamous cell carcinoma. Head Neck. 2011; 33: 1467-1475.
6. Liao CT, Wang HM, Chang JT, et al. Analysis of risk factors for distant metastases in squamous cell carcinoma of the oral cavity. Cancer. 2007; 110: 1501-1508.
7. Shibuya Y, Hasegawa T, Akashi M, Shigeta T, Minamikawa T, Komori T,. Oral squamous cell carcinoma with multiple neck metastases-cases with more than ten pathologically positive lymph nodes in the unilateral side. J Oral Maxillofac Surg. 2013; 71: 793-797.
8. Liao CT, Huang SF, Chen IH, et al. Outcome analysis of patients with pN2 oral cavity cancer. Ann Surg Oncol. 2010; 17: 1118-1126.
9. Akaike H,. New look at statistical-model identification. IEEE Trans Automat Contr. 1982; 19: 716-723.
10. American Joint Committee for Cancer Staging and End Results Reporting. Manual for Staging of Cancer. Chicago: American Joint Committee; 1977.
11. Chandler JR, Guillamondegui OM, Sisson GA, Strong EW, Baker HW. Clinical staging of cancer of the head and neck: a new "new" system. Am J Surg. 1976; 132: 525-528.
12. Spiro RH, Alfonso AE, Farr HW, Strong EW,. Cervical node metastasis from epidermoid carcinoma of the oral cavity and oropharynx. A critical assessment of current staging. Am J Surg. 1974; 128: 562-567.
13. Lindberg R,. Distribution of cervical lymph node metastases from squamous cell carcinoma of the upper respiratory and digestive tracts. Cancer. 1972; 29: 1446-1449.