Angiotensin-converting enzyme 2 is a critical determinant of angiotensin II-induced loss of vascular smooth muscle cells and adverse vascular remodeling

Hypertension

Volumn 64, Issue 1, 2014, Pages 157-164

  Patel, Vaibhav B ^a   Zhong, Jiu Chang ^b,c   Fan, Dong ^a   Basu, Ratnadeep ^a   Morton, Jude S ^a   Parajuli, Nirmal ^a   McMurtry, Michael Sean ^a   Davidge, Sandra T ^a   Kassiri, Zamaneh ^a   Oudit, Gavin Y ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c Shanghai Institute of Hypertension   (China)

Author keywords

angiotensin converting enzyme 2; angiotensin II; irbesartan

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ANGIOTENSIN CONVERTING ENZYME 2; ANGIOTENSIN II; ANGIOTENSIN[1-7]; CALPONIN; CASPASE 3; CASPASE 8; GELATINASE A; GELATINASE B; REACTIVE OXYGEN METABOLITE;

ANIMAL TISSUE; AORTA; APOPTOSIS; ARTERIAL STIFFNESS; ARTERY MEDIA; ARTICLE; BICUSPID AORTIC VALVE; BLOOD VESSEL REACTIVITY; CELL DENSITY; CONTROLLED STUDY; EX VIVO STUDY; GENE INACTIVATION; HISTOLOGY; HUMAN; HUMAN TISSUE; MESENTERIC ARTERY; MOUSE; MYOGRAPHY; NONHUMAN; OXIDATIVE STRESS; PRESSURE; PRIORITY JOURNAL; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SMOOTH MUSCLE FIBER; UPREGULATION; VASCULAR DISEASE; VASCULAR REMODELING; VASCULAR SMOOTH MUSCLE;

ANGIOTENSIN CONVERTING ENZYME 2; ANGIOTENSIN II; IRBESARTAN;

ANGIOTENSIN II; ANIMALS; AORTA; APOPTOSIS; CARDIOMYOPATHY, DILATED; HUMANS; MALE; MATRIX METALLOPROTEINASES; MICE; MICE, KNOCKOUT; MIDDLE AGED; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; OXIDATIVE STRESS; PEPTIDYL-DIPEPTIDASE A; REACTIVE OXYGEN SPECIES; RENIN-ANGIOTENSIN SYSTEM; UP-REGULATION; VASCULAR STIFFNESS; VENTRICULAR REMODELING;

EID: 84902532919     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.114.03388     Document Type: Article

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