Regulation of ionizing radiation-induced adhesion of breast cancer cells to fibronectin by alpha5beta1 integrin

Radiation Research

Volumn 181, Issue 6, 2014, Pages 650-658

  Lee, Shin Hee ^a   Cheng, Huiwen ^a   Yuan, Ye ^a   Wu, Shiyong ^a  

^a OHIO UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; CHECKPOINT KINASE RAD3; COLLAGEN TYPE 1; COLLAGEN TYPE 4; FIBRONECTIN; INTEGRIN; LAMININ; PEPTIDE; PHOSPHOTRANSFERASE INHIBITOR; VERY LATE ACTIVATION ANTIGEN 5;

ARTICLE; ATAXIA TELANGIECTASIA; BREAST CANCER; CANCER CELL CULTURE; CELL ADHESION; CELL MIGRATION; HUMAN; HUMAN CELL; IONIZING RADIATION; METASTASIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN MOTIF;

ATAXIA TELANGIECTASIA MUTATED PROTEINS; BREAST NEOPLASMS; CELL ADHESION; EXTRACELLULAR MATRIX PROTEINS; FEMALE; FIBRONECTINS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INTEGRIN ALPHA5BETA1; MCF-7 CELLS; OLIGOPEPTIDES; PROTEIN BINDING; RADIATION, IONIZING;

EID: 84902525768     PISSN: 00337587     EISSN: 19385404     Source Type: Journal    
DOI: 10.1667/RR13543.1     Document Type: Article

References (22)

1. Hehlgans S, Haase M, Cordes N. Signalling via integrins: implications for cell survival and anticancer strategies. Biochim Biophys Acta 2007; 1775:163-80.
2. Gahmberg CG, Fagerholm SC, Nurmi SM, Chavakis T, Marchesan S, Gronholm M. Regulation of integrin activity and signalling. Biochim Biophys Acta 2009; 1790:431-44.
3. Caswell PT, Spence HJ, Parsons M, White DP, Clark K, Cheng KW, et al. Rab25 associates with alpha5beta1 integrin to promote invasive migration in 3D microenvironments. Dev Cell 2007; 13:496-510.
4. Walsh N, Clynes M, Crown J, O'Donovan N. Alterations in integrin expression modulates invasion of pancreatic cancer cells. J Exp Clin Cancer Res 2009; 28:140.
5. Guo W, Giancotti FG. Integrin signalling during tumour progression. Nat Rev Mol Cell Biol 2004; 5:816-26.
6. Wild-Bode C, Weller M, Rimner A, Dichgans J, Wick W. Sublethal irradiation promotes migration and invasiveness of glioma cells: implications for radiotherapy of human glioblastoma. Cancer Res 2001; 61:2744-50.
7. Meineke V, Gilbertz KP, Schilperoort K, Cordes N, Sendler A, Moede T, et al. Ionizing radiation modulates cell surface integrin expression and adhesion of COLO-320 cells to collagen and fibronectin in vitro. Strahlenther Onkol 2002; 178:709-14.
8. Lee M, Lee HJ, Seo WD, Park KH, Lee YS. Sialylation of integrin beta1 is involved in radiation-induced adhesion and migration in human colon cancer cells. Int J Radiat Oncol Biol Phys 2010; 76:1528-36.
9. Cordes N, Blaese MA, Meineke V, Van Beuningen D. Ionizing radiation induces upregulation of functional beta1-integrin in human lung tumour cell lines in vitro. Int J Radiat Biol 2002; 78:347-57.
10. Yao H, Zeng ZZ, Fay KS, Veine DM, Staszewski ED, Morgan M, et al. Role of alpha(5)beta(1) Integrin Up-regulation in Radiation- Induced Invasion by Human Pancreatic Cancer Cells. Transl Oncol 2011; 4:282-92.
11. Margadant C, Monsuur HN, Norman JC, Sonnenberg A. Mechanisms of integrin activation and trafficking. Curr Opin Cell Biol 2011; 23:607-14.
12. Takada Y, Murphy E, Pil P, Chen C, Ginsberg MH, Hemler ME. Molecular cloning and expression of the cDNA for alpha 3 subunit of human alpha 3 beta 1 (VLA-3), an integrin receptor for fibronectin, laminin, and collagen. J Cell Biol 1991; 115:257-66.
13. Pandita TK, Lieberman HB, Lim DS, Dhar S, Zheng W, Taya Y, et al. Ionizing radiation activates the ATM kinase throughout the cell cycle. Oncogene 2000; 19:1386-91.
14. Sengupta S, Harris CC. p53: traffic cop at the crossroads of DNA repair and recombination. Nat Rev Mol Cell Biol 2005; 6:44-55.
15. Alao JP, Sunnerhagen P. The ATM and ATR inhibitors CGK733 and caffeine suppress cyclin D1 levels and inhibit cell proliferation. Radiat Oncol 2009; 4:51.
16. Stetler-Stevenson WG, Aznavoorian S, Liotta LA. Tumor cell interactions with the extracellular matrix during invasion and metastasis. Annu Rev Cell Biol. 1993; 9:541-73.
17. von Essen CF. Radiation enhancement of metastasis: a review. Clin Exp Metastasis 1991; 9:77-104.
18. Madani I, De Neve W, Mareel M. Does ionizing radiation stimulate cancer invasion and metastasis? Bull Cancer 2008; 95:292-300.
19. Mierke CT, Frey B, Fellner M, Herrmann M, Fabry B. Integrin alpha5beta1 facilitates cancer cell invasion through enhanced contractile forces. J Cell Sci 2011; 124:369-83.
20. Hood JD, Cheresh DA. Role of integrins in cell invasion and migration. Nat Rev Cancer 2002; 2:91-100.
21. Palecek SP, Loftus JC, Ginsberg MH, Lauffenburger DA, Horwitz AF. Integrin-ligand binding properties govern cell migration speed through cell-substratum adhesiveness. Nature 1997; 385:537-40.
22. Holly SP, Larson MK, Parise LV. Multiple roles of integrins in cell motility. Exp Cell Res 2000; 261:69-74.