Microfluidic system for the study of mechanical and biochemical response of endothelial cells to flow-induced mechanical stimuli

12th International Conference on Miniaturized Systems for Chemistry and Life Sciences - The Proceedings of MicroTAS 2008 Conference

Volumn , Issue , 2008, Pages 1858-1860

  Rossi, Massimiliano ^a   Lindken, Ralph ^a   Hierck, Beerend P ^b   Westerweel, Jerry ^a  

^a DELFT UNIVERSITY OF TECHNOLOGY   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Endothelial cells; Microfluidics; Shear stress; PIV

Indexed keywords

FLUIDIC DEVICES; GENE EXPRESSION; MICROFLUIDICS; SHEAR STRESS; VELOCITY MEASUREMENT;

BIOCHEMICAL RESPONSE; EXPRESSION MEASUREMENTS; IN-VITRO; INDIVIDUAL CELLS; MECHANICAL STIMULUS; MICRO FLUIDIC SYSTEM; PIV MEASUREMENTS; STRESS GRADIENT;

ENDOTHELIAL CELLS;

EID: 84902491623     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (4)

1. P.F. Davies, Flow-mediated endothelial mechanotransduction, Physiological Reviews, pp. 519-560, (1995).
2. B.P. Hierck et al., Primary cilia sensitize endothelial cells for fluid shear stress, Development Dynamic, pp. 725-735, (2008).
3. S.W. Stone, C.D. Meinhart and S.T. Wereley, A microfluidic-based nanoscope, Experiments in Fluids, pp. 613-619, (2002).
4. K.A. Barbee, Role of subcellular shear-stress distributions in endothelial cell mechanotransduction, Annals of Biomedical Engineering, pp. 472-482, (2002).