HMG-CoA reductase inhibitors pravastatin, lovastatin and simvastatin suppress delayed rectifier K+-channel currents in murine thymocytes

Pharmacological Reports

Volumn 66, Issue 4, 2014, Pages 712-717

  Kazama, Itsuro ^a   Baba, Asuka ^a   Maruyama, Yoshio ^a  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

HMG CoA reductase inhibitors (statins); Immunosuppressive effects; Kv1.3 channel; Lymphocytes

Indexed keywords

MEVINOLIN; POTASSIUM CHANNEL KV1.3; PRAVASTATIN; SIMVASTATIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IMMUNOSUPPRESSIVE AGENT;

ANIMAL CELL; ARTICLE; CELL MEMBRANE CONDUCTANCE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG MECHANISM; IMMUNOMODULATION; MALE; MOUSE; NONHUMAN; POTASSIUM CURRENT; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL MEMBRANE; DRUG EFFECTS; IMMUNOLOGY; INBRED MOUSE STRAIN; METABOLISM; THYMOCYTE;

ANIMALS; CELL MEMBRANE; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; IMMUNOSUPPRESSIVE AGENTS; KV1.3 POTASSIUM CHANNEL; LOVASTATIN; MALE; MICE, INBRED STRAINS; PRAVASTATIN; SIMVASTATIN; THYMOCYTES;

EID: 84902477781     PISSN: 22995684     EISSN: 22995684     Source Type: Journal    
DOI: 10.1016/j.pharep.2014.03.002     Document Type: Article

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