Real-time measurement of cellular refractive index and thickness using cell culture chip

12th International Conference on Miniaturized Systems for Chemistry and Life Sciences - The Proceedings of MicroTAS 2008 Conference

Volumn , Issue , 2008, Pages 1873-1875

  Gu, J J ^a   Yu, Y F ^a   Li, E P ^b   Ng, S H ^c   Yap, P H ^c   Zhou, X Q ^d   Cheng, T H ^a   Liu, A Q ^a  

^a NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

^b INSTITUTE OF HIGH PERFORMANCE COMPUTING   (Singapore)

^c DSO NATIONAL LABORATORIES   (Singapore)

^d INSTITUTE FOR INFOCOMM RESEARCH   (Singapore)

Author keywords

Cell culture; Immersion refractometry; Lab on a chip; Refractive index

Indexed keywords

BIOINFORMATICS; DAMAGE DETECTION; LAB-ON-A-CHIP; REFRACTIVE INDEX;

CANCER CELL DETECTION; LIVING CELL; MADIN-DARBY CANINE KIDNEY CELL LINES (MDCK); MEASUREMENT OF REFRACTIVE INDICES; PATHOLOGICAL CHANGES; REAL TIME MEASUREMENTS; REFRACTOMETRY;

CELL CULTURE;

EID: 84902449565     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (3)

1. C. L. Curl, C. J. Bellair, T. Harris, B. E. Allman, P. J. Harris, A. G. Stewart, A. Roberts, K. A. Nugent, and L. M. D. Delbridge, Refractive index measurement in viable cells using quantitative phase-amplitude microscopy and confocal microscopy, Cytometry Part A, 65A, pp. 88-92, (2005).
2. V. Backman, M. B. Wallace, L. T. Perelman, J. T. Arendt, R. Gurjar, M. G. Müller, Q. Zhang, G. Zonios, E. Kline, T. McGillican, S. Shapshay, T. Valdez, K. Badizadegan, J. M. Crawford, M. Fitzmaurice, S. Kabani, H. S. Levin, M. Seiler, R. R. Dasari, I. Itzkan, J. Van Dam & M. S. Feld, Detection of preinvasive cancer cells, Nature, 406, pp. 35-36, (2000).
3. P. J. Hung, P. J. Lee, P. Sabounchi, N. Aghdam, R. Lin and L. P. Lee, A novel high aspect ratio microfluidic design to provide a stable and uniform microenvironment for cell growth in a high throughput mammalian cell culture array, Lab Chip, 5, pp. 44-48, (2005).