Berberine reduces ischemia/reperfusion-induced myocardial apoptosis via activating AMPK and PI3K-Akt signaling in diabetic rats

Apoptosis

Volumn 19, Issue 6, 2014, Pages 946-957

  Chen, Keke ^a,b   Li, Guohua ^a   Geng, Fenghao ^a   Zhang, Zhao ^a   Li, Jiani ^a   Yang, Min ^a   Dong, Ling ^a   Gao, Feng ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b XI'AN UNIVERSITY OF ARTS AND SCIENCE   (China)

Author keywords

Anti apoptosis; Berberine; Cardiomyocytes; Diabetes; Ischemia reperfusion

Indexed keywords

BERBERINE; CASPASE 3; COMPOUND C; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ENZYME INHIBITOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; SODIUM CHLORIDE; STREPTOZOCIN; UNCLASSIFIED DRUG; WORTMANNIN; ANDROSTANE DERIVATIVE; ANTIDIABETIC AGENT; HYPERGLYCEMIC AGENT; ONCOPROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HYPOXIA; LIPID DIET; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REOXYGENATION; REPERFUSION INJURY; SIGNAL TRANSDUCTION; ANIMAL; CHEMICALLY INDUCED; COMPLICATION; DRUG EFFECTS; EXPERIMENTAL DIABETES MELLITUS; FEMALE; HEART; HEART MUSCLE; METABOLISM; MYOCARDIAL REPERFUSION INJURY; NEWBORN; PATHOLOGY; PATHOPHYSIOLOGY; SPRAGUE DAWLEY RAT;

RATTUS;

AMP-ACTIVATED PROTEIN KINASES; ANDROSTADIENES; ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; BERBERINE; DIABETES MELLITUS, EXPERIMENTAL; FEMALE; HEART; HYPOGLYCEMIC AGENTS; INSULIN ANTAGONISTS; MALE; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; MYOCYTES, CARDIAC; ONCOGENE PROTEIN V-AKT; PHOSPHATIDYLINOSITOL 3-KINASES; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; STREPTOZOCIN;

EID: 84902383743     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-014-0977-0     Document Type: Article

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