메뉴 건너뛰기




Volumn 9, Issue 6, 2014, Pages

A meta analysis of lumbar spinal fusion surgery using bone morphogenetic proteins and autologous iliac crest bone graft

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 2; OSTEOGENIC PROTEIN 1;

EID: 84902352357     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0097049     Document Type: Article
Times cited : (30)

References (53)
  • 2
    • 34250019537 scopus 로고
    • Bone Formation by autoinduction
    • doi:10.1126/science.150.3698.893
    • Urist MR (1965) Bone Formation by autoinduction. Science 150: 893-899. doi:10.1126/science.150.3698.893.
    • (1965) Science , vol.150 , pp. 893-899
    • Urist, M.R.1
  • 4
    • 0017360990 scopus 로고
    • The measurement of observer agreement for categorical data
    • Landis JR,Koch GG (1977) The measurement of observer agreement for categorical data. Biometrics 33: 159-174. doi:10.2307/2529310. (Pubitemid 8054849)
    • (1977) Biometrics , vol.33 , Issue.1 , pp. 159-174
    • Landis, J.R.1    Koch, G.G.2
  • 5
    • 18544372466 scopus 로고    scopus 로고
    • Understanding interobserver agreement: The kappa statistic
    • Viera AJ, Garrett JM (2005) Understanding interobserver agreement: the kappa statistic.Fam Med 37: 360-363. (Pubitemid 40656185)
    • (2005) Family Medicine , vol.37 , Issue.5 , pp. 360-363
    • Viera, A.J.1    Garrett, J.M.2
  • 6
    • 69749109780 scopus 로고    scopus 로고
    • 2009 updated method guidelines for systematic reviews in the Cochrane Back Review Group
    • doi:10.1097/BRS.0b013e3181b1c99f
    • Furlan AD, Pennick V, Bombardier C, van Tulder M (2009) 2009 updated method guidelines for systematic reviews in the Cochrane Back Review Group. Spine. doi:10.1097/BRS.0b013e3181b1c99f.
    • (2009) Spine
    • Furlan, A.D.1    Pennick, V.2    Bombardier, C.3    Van Tulder, M.4
  • 8
    • 0022992740 scopus 로고
    • Meta-analysis in clinical trials
    • DOI 10.1016/0197-2456(86)90046-2
    • DerSimonian R, Laird N (1986) Meta-analysis in clinical trials. Control Clin Trials 7: 177-188. doi:10.1016/0197-2456(86)90046-2. (Pubitemid 17189972)
    • (1986) Controlled Clinical Trials , vol.7 , Issue.3 , pp. 177-188
    • DerSimonian, R.1    Laird, N.2
  • 9
    • 0030922816 scopus 로고    scopus 로고
    • Bias in meta-analysis detected by a simple, graphical test
    • Egger M, Smith GD, Schneider M, Minder C (2000) Bias in meta-analysis detected by a simple, graphical test. BMJ 315: 629-634. doi:10.1136/bmj.315. 7109.629. (Pubitemid 27387172)
    • (1997) British Medical Journal , vol.315 , Issue.7109 , pp. 629-634
    • Egger, M.1    Smith, G.D.2    Schneider, M.3    Minder, C.4
  • 10
    • 0028659004 scopus 로고
    • Operating characteristics of a rank correlation test for publication bias
    • doi:10.2307/2533446
    • Begg CB, Mazumdar M (1994) Operating characteristics of a rank correlation test for publication bias. Biometrics 50: 1088-1101. doi:10.2307/2533446.
    • (1994) Biometrics , vol.50 , pp. 1088-1101
    • Begg, C.B.1    Mazumdar, M.2
  • 11
    • 0032477417 scopus 로고    scopus 로고
    • Bias in location and selection of studies
    • doi:10.1136/bmj.316.7124.61
    • Egger M, Smith GD (1998) Bias in location and selection of studies. BMJ 316: 61-66. doi:10.1136/bmj.316.7124.61.
    • (1998) BMJ , vol.316 , pp. 61-66
    • Egger, M.1    Smith, G.D.2
  • 12
    • 0033934949 scopus 로고    scopus 로고
    • Trim and fill: A simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis
    • Duval S, Tweedie R (2000) Trim and fill: a simple funnel-plot based method of testing and adjusting for publication bias in meta-analysis. Biometrics 56: 455-463. doi:10.1111/j.0006-341X.2000.00455.x. (Pubitemid 30422636)
    • (2000) Biometrics , vol.56 , Issue.2 , pp. 455-463
    • Duval, S.1    Tweedie, R.2
  • 13
    • 0034631415 scopus 로고    scopus 로고
    • Empirical assessment of effect of publication bias on meta-analyses
    • Sutton AJ, Duval SJ, Tweedie RL, Abrams KR, Jones DR (2000) Empirical assessment of effect of publication bias on meta-analyses. BMJ 320: 1574-1577. doi:10.1136/bmj.320.7249.1574. (Pubitemid 30336090)
    • (2000) British Medical Journal , vol.320 , Issue.7249 , pp. 1574-1577
    • Sutton, A.J.1    Duval, S.J.2    Tweedie, R.L.3    Abrams, K.R.4    Jones, D.R.5
  • 14
    • 0033954803 scopus 로고    scopus 로고
    • The use of rhBMP-2 in interbody fusion cages. Definitive evidence of osteoinduction in humans: A preliminary report
    • DOI 10.1097/00007632-200002010-00020
    • Boden SD, Zdeblick TA, Sandhu HS, Heim SE (2000) The use of rhBMP-2 in interbody fusion cages. Definitive evidence of osteoinduction in humans: a preliminary report. Spine 25: 376-381. doi:10.1097/00007632-200002010-00020. (Pubitemid 30097051)
    • (2000) Spine , vol.25 , Issue.3 , pp. 376-381
    • Boden, S.D.1    Zdeblick, T.A.2    Sandhu, H.S.3    Heim, S.E.4
  • 15
    • 0036894554 scopus 로고    scopus 로고
    • Use of recombinant human bone morphogenetic protein-2 to achieve posterolateral lumbar spine fusion in humans: A prospective, randomized clinical pilot trial 2002 volvo award in clinical studies
    • DOI 10.1097/00007632-200212010-00005
    • Boden SD, Kang J, Sandhu H, Heller JG (2002) Use of recombinant human bone morphogenetic protein-2 to achieve posterolateral lumbar spine fusion in humans: a prospective, randomized clinical pilot trial: 2002 Volvo Award in clinical studies. Spine 27: 2662-2673. doi:10.1097/00007632-200212010-00005. (Pubitemid 35425320)
    • (2002) Spine , vol.27 , Issue.23 , pp. 2662-2673
    • Boden, S.D.1    Kang, J.2    Sandhu, H.3    Heller, J.G.4
  • 16
    • 0036815167 scopus 로고    scopus 로고
    • Anterior lumbar interbody fusion using rhBMP-2 with tapered interbody cages
    • doi:10.1097/00024720-200210000-00001
    • Burkus JK, Gornet MF, Dickman CA, Zdeblick TA (2002) Anterior lumbar interbody fusion using rhBMP-2 with tapered interbody cages. J Spinal Disord Tech 15: 337-349. doi:10.1097/00024720-200210000-00001.
    • (2002) J Spinal Disord Tech , vol.15 , pp. 337-349
    • Burkus, J.K.1    Gornet, M.F.2    Dickman, C.A.3    Zdeblick, T.A.4
  • 17
    • 0036843201 scopus 로고    scopus 로고
    • Clinical and radiographic outcomes of anterior lumbar interbody fusion using recombinant human bone morphogenetic protein-2
    • DOI 10.1097/00007632-200211010-00015
    • Burkus JK, Transfeldt EE, Kitchel SH, Watkins RG, Balderston RA (2002) Clinical and radiographic outcomes of anterior lumbar interbody fusion using recombinant human bone morphogenetic protein-2. Spine 27: 2396-2408. doi:10.1097/00007632-200211010-00015. (Pubitemid 35266228)
    • (2002) Spine , vol.27 , Issue.21 , pp. 2396-2408
    • Burkus, J.K.1    Transfeldt, E.E.2    Kitchel, S.H.3    Watkins, R.G.4    Balderston, R.A.5
  • 18
    • 0036897076 scopus 로고    scopus 로고
    • Randomized radiostereometric study comparing osteogenic protein-1 (BMP-7) and autograft bone in human noninstrumented posterolateral lumbar fusion: 2002 Volvo Award in clinical studies
    • doi:10.1097/00007632-200212010-00004
    • Johnsson R, Strömqvist B, Aspenberg P (2002) Randomized radiostereometric study comparing osteogenic protein-1 (BMP-7) and autograft bone in human noninstrumented posterolateral lumbar fusion: 2002 Volvo Award in clinical studies. spine 27: 2654-2661. doi:10.1097/00007632-200212010-00004.
    • (2002) Spine , vol.27 , pp. 2654-2661
    • Johnsson, R.1    Strömqvist, B.2    Aspenberg, P.3
  • 19
    • 0037442894 scopus 로고    scopus 로고
    • Radiographic assessment of interbody fusion using recombinant human bone morphogenetic protein type 2
    • doi:10.1097/01.BRS. 0000048469.45035.B9
    • Burkus JK, Dorchak JD, Sanders DL (2003) Radiographic assessment of interbody fusion using recombinant human bone morphogenetic protein type 2. Spine 28: 372-377. doi:10.1097/01.BRS. 0000048469.45035.B9.
    • (2003) Spine , vol.28 , pp. 372-377
    • Burkus, J.K.1    Dorchak, J.D.2    Sanders, D.L.3
  • 20
    • 11144250305 scopus 로고    scopus 로고
    • Posterior lumbar interbody fusion using recombinant human bone morphogenetic protein type 2 with cylindrical interbody cages
    • DOI 10.1016/j.spinee.2004.03.025, PII S1529943004001470
    • Haid RW Jr, Branch CL Jr, Alexander JT, Burkus JK (2004) Posterior lumbar interbody fusion using recombinant human bone morphogenetic protein type 2 with cylindrical interbody cages. Spine J 4: 527-538. doi:10.1016/j.spinee.2004.03. 025. (Pubitemid 40029169)
    • (2004) Spine Journal , vol.4 , Issue.5 , pp. 527-538
    • Haid Jr., R.W.1    Branch Jr., C.L.2    Alexander, J.T.3    Burkus, J.K.4
  • 21
    • 34748844937 scopus 로고    scopus 로고
    • A prospective randomized clinical study comparing instrumented lumbar fusion rates of Recombinant Human Bone Morphogenic Protein-2 (rhBMP-2) with autogenous iliac crest bone graft in patients with symptomatic degenerative disc disease
    • Assiri I, du Plessis S, Hurlbert J, Hu R, Salo P, et al. (2004) A prospective randomized clinical study comparing instrumented lumbar fusion rates of Recombinant Human Bone Morphogenic Protein-2 (rhBMP-2) with autogenous iliac crest bone graft in patients with symptomatic degenerative disc disease. Canadian Journal of Surgery (Suppl 4): 7-8.
    • (2004) Canadian Journal of Surgery , Issue.SUPPL. 4 , pp. 7-8
    • Assiri, I.1    Du Plessis, S.2    Hurlbert, J.3    Hu, R.4    Salo, P.5
  • 22
    • 23244467021 scopus 로고    scopus 로고
    • Initial fusion rates with recombinant human bone morphogenetic protein-2/compression resistant matrix and a hydroxyapatite and tricalcium phosphate/collagen carrier in posterolateral spinal fusion
    • doi:10.1097/01. brs.0000172157.39513.80
    • Glassman SD, Dimar JR, Carreon LY, Campbell MJ, Puno RM, et al. (2005) Initial fusion rates with recombinant human bone morphogenetic protein-2/compression resistant matrix and a hydroxyapatite and tricalcium phosphate/collagen carrier in posterolateral spinal fusion. Spine 30: 1694-1698. doi:10.1097/01. brs.0000172157.39513.80.
    • (2005) Spine , vol.30 , pp. 1694-1698
    • Glassman, S.D.1    Dimar, J.R.2    Carreon, L.Y.3    Campbell, M.J.4    Puno, R.M.5
  • 24
    • 19944417622 scopus 로고    scopus 로고
    • Use of rhBMP-2 in combination with structural cortical allografts: Clinical and radiographic outcomes in anterior lumbar spinal surgery
    • doi:10.2106/JBJS.D.02532
    • Burkus JK, Sandhu HS, Gornet MF, Lonely MC (2005) Use of rhBMP-2 in combination with structural cortical allografts: clinical and radiographic outcomes in anterior lumbar spinal surgery. J Bone Joint Surg Am 87: 1205-1212. doi:10.2106/JBJS.D.02532.
    • (2005) J Bone Joint Surg Am , vol.87 , pp. 1205-1212
    • Burkus, J.K.1    Sandhu, H.S.2    Gornet, M.F.3    Lonely, M.C.4
  • 25
    • 33750290922 scopus 로고    scopus 로고
    • Clinical outcomes and fusion success at 2 years of single-level instrumented posterolateral fusions with recombinant human bone morphogenetic protein-2/compression resistant matrix versus iliac crest bone graft
    • DOI 10.1097/01.brs.0000240715.78657.81, PII 0000763220061015000005
    • Dimar JR, Glassman SD, Burkus KJ, Carreon LY (2006) Clinical outcomes and fusion success at 2 years of single-level instrumented posterolateral fusions with recombinant human bone morphogenetic protein-2/compression resistant matrix versus iliac crest bone graft. Spine 31: 2534-2539. doi:10.1097/01.brs. 0000240715.78657.81. (Pubitemid 44632234)
    • (2006) Spine , vol.31 , Issue.22 , pp. 2534-2539
    • Dimar, J.R.1    Glassman, S.D.2    Burkus, K.J.3    Carreon, L.Y.4
  • 26
    • 33646573974 scopus 로고    scopus 로고
    • A prospective randomized study of posterolateral lumbar fusion using osteogenic protein-1 (OP-1) versus local autograft with ceramic bone substitute: Emphasis of surgical exploration and histologic assessment
    • doi:10.1097/01.brs.0000216444.01888.21
    • Kanayama M, Hashimoto T, Shigenobu K, Yamane S, Bauer TW, et al. (2006) A prospective randomized study of posterolateral lumbar fusion using osteogenic protein-1 (OP-1) versus local autograft with ceramic bone substitute: emphasis of surgical exploration and histologic assessment. Spine 31: 1067-1074. doi:10.1097/01.brs.0000216444.01888.21.
    • (2006) Spine , vol.31 , pp. 1067-1074
    • Kanayama, M.1    Hashimoto, T.2    Shigenobu, K.3    Yamane, S.4    Bauer, T.W.5
  • 27
    • 67650128701 scopus 로고    scopus 로고
    • RhBMP-2 versus iliac crest bone graft for lumbar spine fusion: A randomized, controlled trial in patients over 60 years of age
    • doi:10.1097/BRS.0b013e318190705d
    • Glassman SD, Carreon LY, Djurasovic M, Campbell MJ, Puno RM, et al. (2008) RhBMP-2 versus iliac crest bone graft for lumbar spine fusion: a randomized, controlled trial in patients over 60 years of age. Spine 33: 2843-2849. doi:10.1097/BRS.0b013e318190705d.
    • (2008) Spine , vol.33 , pp. 2843-2849
    • Glassman, S.D.1    Carreon, L.Y.2    Djurasovic, M.3    Campbell, M.J.4    Puno, R.M.5
  • 28
    • 66449124629 scopus 로고    scopus 로고
    • The safety and efficacy of OP-1 (rhBMP-7) as a replacement for iliac crest autograft in posterolateral lumbar arthrodesis: A long-term (>4 years) pivotal study
    • doi:10.1097/BRS.0b013e31818a314d
    • Vaccaro AR, Lawrence JP, Patel T, Katz LD, Anderson DG, et al. (2008) The safety and efficacy of OP-1 (rhBMP-7) as a replacement for iliac crest autograft in posterolateral lumbar arthrodesis: a long-term (>4 years) pivotal study. Spine 33: 2850-2862. doi:10.1097/BRS.0b013e31818a314d.
    • (2008) Spine , vol.33 , pp. 2850-2862
    • Vaccaro, A.R.1    Lawrence, J.P.2    Patel, T.3    Katz, L.D.4    Anderson, D.G.5
  • 29
    • 67649870799 scopus 로고    scopus 로고
    • Clinical and radiographic analysis of an optimized rhBMP-2 formulation as an autograft replacement in posterolateral lumbar spine arthrodesis
    • doi:10.2106/JBJS.H.00200
    • Dimar JR 2nd, Glassman SD, Burkus JK, Pryor PW, Hardacker JW, et al. (2009) Clinical and radiographic analysis of an optimized rhBMP-2 formulation as an autograft replacement in posterolateral lumbar spine arthrodesis. Journal Bone Joint Surg Am 91: 1377-1386. doi:10.2106/JBJS.H.00200.
    • (2009) Journal Bone Joint Surg Am , vol.91 , pp. 1377-1386
    • Dimar II, J.R.1    Glassman, S.D.2    Burkus, J.K.3    Pryor, P.W.4    Hardacker, J.W.5
  • 30
    • 67651148520 scopus 로고    scopus 로고
    • Recombinant human bone morphogenetic protein-2 on an absorbable collagen sponge with an osteoconductive bulking agent in posterolateral arthrodesis with instrumentation. A prospective randomized trial
    • doi:10.2106/JBJS.G.01157
    • Dawson E, Bae HW, Burkus JK, Stambough JL, Glassman SD (2009) Recombinant human bone morphogenetic protein-2 on an absorbable collagen sponge with an osteoconductive bulking agent in posterolateral arthrodesis with instrumentation. A prospective randomized trial. J Bone Joint Surg Am 91: 1604-1613. doi:10.2106/JBJS.G.01157.
    • (2009) J Bone Joint Surg Am , vol.91 , pp. 1604-1613
    • Dawson, E.1    Bae, H.W.2    Burkus, J.K.3    Stambough, J.L.4    Glassman, S.D.5
  • 31
    • 77953020026 scopus 로고    scopus 로고
    • A prospective, randomized, controlled, multicenter study of osteogenic protein-1 in instrumented posterolateral fusions: Report on safety and feasibility
    • doi:10.1097/BRS.0b013e3181d3cf28
    • Delawi D, Dhert WJ, Rillardon L, Gay E, Prestamburgo D, et al. (2010) A prospective, randomized, controlled, multicenter study of osteogenic protein-1 in instrumented posterolateral fusions: report on safety and feasibility. Spine 35: 1185-1191. doi:10.1097/BRS.0b013e3181d3cf28.
    • (2010) Spine , vol.35 , pp. 1185-1191
    • Delawi, D.1    Dhert, W.J.2    Rillardon, L.3    Gay, E.4    Prestamburgo, D.5
  • 32
    • 84879755369 scopus 로고    scopus 로고
    • The effect of recombinant human bone morphogenetic protein-2 in single-level posteriorlumbar interbody arthrodesis
    • doi:10.2106/JBJS.L.00137
    • Michielsen J, Sys J, Rigaux A, Bertrand C (2013) The effect of recombinant human bone morphogenetic protein-2 in single-level posteriorlumbar interbody arthrodesis. J Bone Joint Surg Am 95: 873-880. doi:10.2106/JBJS.L. 00137.
    • (2013) J Bone Joint Surg Am , vol.95 , pp. 873-880
    • Michielsen, J.1    Sys, J.2    Rigaux, A.3    Bertrand, C.4
  • 33
    • 0043069482 scopus 로고    scopus 로고
    • Summary statement: Emerging techniques for treatment of degenerative lumbar disc disease
    • An H, Boden SD, Kang J, Sandhu HS, Abdu W, et al. (2003) Summary statement: emerging techniques for treatment of degenerative lumbar disc disease. Spine 28: S24-S25. doi:10.1097/01.BRS.0000076894.33269.19. (Pubitemid 36959579)
    • (2003) Spine , vol.28 , Issue.15 SUPPL.
    • An, H.1    Boden, S.D.2    Kang, J.3    Sandhu, H.S.4    Abdu, W.5    Weinstein, J.6
  • 34
    • 0024377022 scopus 로고
    • Morbidity at bone graft donor sites
    • doi:10.1097/00005131-198909000-00002
    • Younger EM, Chapman MW (1989) Morbidity at bone graft donor sites. J Orthop Trauma 3: 192-195. doi:10.1097/00005131-198909000-00002.
    • (1989) J Orthop Trauma , vol.3 , pp. 192-195
    • Younger, E.M.1    Chapman, M.W.2
  • 35
    • 0028922670 scopus 로고
    • Iliac crest bone graft harvest donor site morbidity: A statistical evaluation
    • doi:10.1097/00007632-199505000-00012
    • Banwart JC, Asher MA, Hassanein RS (1995) Iliac crest bone graft harvest donor site morbidity: a statistical evaluation. Spine 20: 1055-1060. doi:10.1097/00007632-199505000-00012.
    • (1995) Spine , vol.20 , pp. 1055-1060
    • Banwart, J.C.1    Asher, M.A.2    Hassanein, R.S.3
  • 36
    • 0027983108 scopus 로고
    • Midline fascial splitting approach to the iliac crest for bone graft: A new approach
    • Hutchinson MR, Dall BE (1994) Midline fascial splitting approach to the iliac crest for bone graft: a new approach. Spine 19: 62-66. doi:10.1097/00007632-199401000-00013. (Pubitemid 24039183)
    • (1994) Spine , vol.19 , Issue.1 , pp. 62-66
    • Hutchinson, M.R.1    Dall, B.E.2
  • 37
    • 0036563385 scopus 로고    scopus 로고
    • Comparison of anterior and posterior iliac crest bone grafts in terms of harvest-site morbidity and functional outcomes
    • Ahlmann E, Patzakis M, Roidis N, Shepherd L, Holtom P (2002) Comparison of anterior and posterior iliac crest bone grafts in terms of harvest-site morbidity and functional outcomes. J Bone Joint Surg Am 84: 716-720.
    • (2002) J Bone Joint Surg Am , vol.84 , pp. 716-720
    • Ahlmann, E.1    Patzakis, M.2    Roidis, N.3    Shepherd, L.4    Holtom, P.5
  • 38
    • 33947323908 scopus 로고    scopus 로고
    • Autologous iliac crest bone graft: Should it still be the gold standard for treating nonunions?
    • DOI 10.1016/j.injury.2007.02.012, PII S0020138307000617
    • Sen MK, Miclau T (2007) Autologous iliac crest bone graft: should it still be the gold standard for treating nonunions? Injury 38 Suppl 1: S75-80.doi:10.1016/j.injury.2007.02.012. (Pubitemid 46440932)
    • (2007) Injury , vol.38 , Issue.SUPPL. 1
    • Sen, M.K.1    Miclau, T.2
  • 39
    • 0031909665 scopus 로고    scopus 로고
    • Role of morphogenetic proteins in skeletal tissue engineering and regeneration
    • doi:10.1038/nbt0398-247
    • Reddi AH (1998) Role of morphogenetic proteins in skeletal tissue engineering and regeneration. Nat Biotechno 16: 247-252. doi:10.1038/nbt0398- 247.
    • (1998) Nat Biotechno , vol.16 , pp. 247-252
    • Reddi, A.H.1
  • 40
    • 27744607999 scopus 로고    scopus 로고
    • Current concepts of molecular aspects of bone healing
    • doi:/10.1016/j.injury.2005.07.019
    • Dimitriou R, Tsiridis E, Giannoudis PV (2005) Current concepts of molecular aspects of bone healing. Injury 36: 1392-1404. doi:/10.1016/j.injury. 2005.07.019.
    • (2005) Injury , vol.36 , pp. 1392-1404
    • Dimitriou, R.1    Tsiridis, E.2    Giannoudis, P.V.3
  • 41
    • 0037102257 scopus 로고    scopus 로고
    • Safety profile for the clinical use of bone morphogenetic proteins in the spine
    • doi:10.1097/00007632-200208151-00010
    • Poynton AR, Lane JM (2002) Safety profile for the clinical use of bone morphogenetic proteins in the spine. Spine 27: S40-48. doi:10.1097/00007632- 200208151-00010.
    • (2002) Spine , vol.27
    • Poynton, A.R.1    Lane, J.M.2
  • 42
    • 53149131019 scopus 로고    scopus 로고
    • A comprehensive review of the safety profile of bone morphogenetic protein in spine surgery
    • discussion ONS431. doi:10.1227/01.neu.0000326030.24220.d8
    • Benglis D, Wang MY, Levi AD (2008) A comprehensive review of the safety profile of bone morphogenetic protein in spine surgery. Neurosurgery 62: ONS423-431; discussion ONS431. doi:10.1227/01.neu.0000326030.24220.d8.
    • (2008) Neurosurgery , vol.62
    • Benglis, D.1    Wang, M.Y.2    Levi, A.D.3
  • 43
    • 79959950769 scopus 로고    scopus 로고
    • A critical review of recombinant human bone morphogenetic protein-2 trials in spinal surgery: Emerging safety concerns and lessons learned
    • doi:10.1016/j.spinee.2011.04.023
    • Carragee EJ,Hurwitz EL, Weiner BK (2011) A critical review of recombinant human bone morphogenetic protein-2 trials in spinal surgery: emerging safety concerns and lessons learned. Spine J 11: 471-491. doi:10.1016/j.spinee.2011.04. 023.
    • (2011) Spine J , vol.11 , pp. 471-491
    • Carragee, E.J.1    Hurwitz, E.L.2    Weiner, B.K.3
  • 44
    • 34147100125 scopus 로고    scopus 로고
    • Bone morphogenetic proteins and bone defects: A systematic review
    • DOI 10.1097/01.brs.0000259227.51180.ca, PII 0000763220070401000019
    • Mussano F, Ciccone G, Ceccarelli M, Baldi I, Bassi F (2007) Bone morphogenetic proteins and bone defects: a systematic review. Spine 32: 824-830. doi:10.1097/01.brs.0000259227.51180.ca. (Pubitemid 46573337)
    • (2007) Spine , vol.32 , Issue.7 , pp. 824-830
    • Mussano, F.1    Ciccone, G.2    Ceccarelli, M.3    Baldi, I.4    Bassi, F.5
  • 45
    • 55449086014 scopus 로고    scopus 로고
    • Efficacy of autologous iliac crest bone graft and bone morphogenetic proteins for posterolateral fusion of lumbar spine: A meta-analysis of the results
    • doi:10.1097/BRS.0b013e3181844eca
    • Papakostidis C, Kontakis G, Bhandari M, Giannoudis PV (2008) Efficacy of autologous iliac crest bone graft and bone morphogenetic proteins for posterolateral fusion of lumbar spine: a meta-analysis of the results. Spine 33: E680-692. doi:10.1097/BRS.0b013e3181844eca.
    • (2008) Spine , vol.33
    • Papakostidis, C.1    Kontakis, G.2    Bhandari, M.3    Giannoudis, P.V.4
  • 46
    • 73249116149 scopus 로고    scopus 로고
    • Osteoinductive bone graft substitutes for lumbar fusion: A systematic review
    • doi:10.3171/2009.6.SPINE08669
    • Agarwal R, Williams K, Umscheid CA, Welch WC (2009) Osteoinductive bone graft substitutes for lumbar fusion: a systematic review. J Neurosurg Spine 11: 729-740. doi:10.3171/2009.6.SPINE08669.
    • (2009) J Neurosurg Spine , vol.11 , pp. 729-740
    • Agarwal, R.1    Williams, K.2    Umscheid, C.A.3    Welch, W.C.4
  • 47
    • 84872116582 scopus 로고    scopus 로고
    • Recombinant human bone morphogenetic protein-2 versus autogenous iliac crest bone graft for lumbar fusion: A meta-analysis of ten randomized controlled trials
    • doi:10.1007/s00402-012-1607-3
    • Chen Z, Ba G, Shen T, Fu Q (2012) Recombinant human bone morphogenetic protein-2 versus autogenous iliac crest bone graft for lumbar fusion: a meta-analysis of ten randomized controlled trials. Arch Orthop Trauma Surg 132: 1725-1740. doi:10.1007/s00402-012-1607-3.
    • (2012) Arch Orthop Trauma Surg , vol.132 , pp. 1725-1740
    • Chen, Z.1    Ba, G.2    Shen, T.3    Fu, Q.4
  • 49
    • 84879177790 scopus 로고    scopus 로고
    • Effectiveness and harms of recombinant human bone morphogenetic protein-2 in spine fusion: A systematic review and meta-analysis
    • doi:10.7326/0003-4819-158-12-201306180-00006
    • Fu R, Selph S, McDonagh M, Peterson K, Tiwari A, et al. (2013) Effectiveness and harms of recombinant human bone morphogenetic protein-2 in spine fusion: a systematic review and meta-analysis. Ann Intern Med. 158: 890-902. doi:10.7326/0003-4819-158-12-201306180-00006.
    • (2013) Ann Intern Med , vol.158 , pp. 890-902
    • Fu, R.1    Selph, S.2    McDonagh, M.3    Peterson, K.4    Tiwari, A.5
  • 50
    • 84879165716 scopus 로고    scopus 로고
    • Safety and effectiveness of recombinant human bone morphogenetic protein-2 for spinal fusion: A meta-analysis of individual-participant data
    • doi:10.7326/0003-4819-158-12-201306180-00005
    • Simmonds MC, Brown JV, Heirs MK, Higgins JP, Mannion RJ, et al. (2013) Safety and effectiveness of recombinant human bone morphogenetic protein-2 for spinal fusion: a meta-analysis of individual-participant data. Ann Intern Med. 158: 877-889. doi:10.7326/0003-4819-158-12-201306180-00005.
    • (2013) Ann Intern Med , vol.158 , pp. 877-889
    • Simmonds, M.C.1    Brown, J.V.2    Heirs, M.K.3    Higgins, J.P.4    Mannion, R.J.5
  • 51
    • 84902336064 scopus 로고    scopus 로고
    • Available: Accessed Dec 12, 2013
    • Yale School of Medicine. Available: http://medicine.yale.edu/core/ projects/ yodap/datasharing/medtronic/463-158787-YorkrhBMP2FinalReport.pdf. Accessed Dec 12, 2013.
  • 52
    • 0027296665 scopus 로고
    • Can lumbar spine radiographs accurately determine fusion in postoperative patients?: Correlation of routine radiographs with a second surgical look at lumbar fusions
    • Blumenthal SL, Gill K (1993) Can lumbar spine radiographs accurately determine fusion in postoperative patients? Correlation of routine radiographs with a second surgical look at lumbar fusions.Spine18: 1186-1189. doi:10.1097/00007632-199307000-00010. (Pubitemid 23210768)
    • (1993) Spine , vol.18 , Issue.9 , pp. 1186-1189
    • Blumenthal, S.L.1    Gill, K.2
  • 53
    • 77951766763 scopus 로고    scopus 로고
    • Complications related to osteobiologics use in spine surgery: A systematic review
    • doi:10.1097/BRS.0b013e3181d81ef2
    • Mroz TE, Wang JC, Hashimoto R, Norvell DC (2010) Complications related to osteobiologics use in spine surgery: a systematic review. Spine 35: S86-104. doi:10.1097/BRS.0b013e3181d81ef2.
    • (2010) Spine , vol.35
    • Mroz, T.E.1    Wang, J.C.2    Hashimoto, R.3    Norvell, D.C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.