Breath tests in the diagnosis of small intestinal bacterial overgrowth in patients with irritable bowel syndrome in comparison with quantitative upper gut aspirate culture

European Journal of Gastroenterology and Hepatology

Volumn 26, Issue 7, 2014, Pages 753-760

  Ghoshal, Uday C ^a   Srivastava, Deepakshi ^a   Ghoshal, Ujjala ^a   Misra, Asha ^a  

^a SANJAY GANDHI POSTGRADUATE INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Breath methane; Chronic diarrhea; Diagnostic criteria; Functional bowel disease; Probiotics; Rifaximin

Indexed keywords

METHANE; GLUCOSE; HYDROGEN; LACTULOSE;

ACINETOBACTER BAUMANNII; ACINETOBACTER LWOFFII; ADULT; ANALYZER; ARTICLE; ASPIRATION; BACTERIAL OVERGROWTH; BACTERIUM COLONY; BACTERIUM CULTURE; COLONY FORMING UNIT; COMPARATIVE STUDY; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; DIARRHEA; ENTEROCOCCUS FAECALIS; ENTEROCOCCUS FAECIUM; ESCHERICHIA COLI; FEMALE; GLUCOSE HYDROGEN BREATH TEST; HUMAN; HYDROGEN BREATH TEST; IRRITABLE COLON; LACTULOSE HYDROGEN BREATH TEST; MAJOR CLINICAL STUDY; MALE; NONHUMAN; PREDICTIVE VALUE; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; SENSITIVITY AND SPECIFICITY; SMALL INTESTINAL BACTERIAL OVERGROWTH; SMALL INTESTINE DISEASE; STAPHYLOCOCCUS; STREPTOCOCCUS; UPPER GUT ASPIRATE CULTURE; ADOLESCENT; AGED; BLIND LOOP SYNDROME; BREATH ANALYSIS; CONTROLLED CLINICAL TRIAL; IRRITABLE BOWEL SYNDROME; METABOLISM; MICROBIOLOGICAL EXAMINATION; MICROBIOLOGY; MICROFLORA; MIDDLE AGED; SMALL INTESTINE; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; BLIND LOOP SYNDROME; BREATH TESTS; DIARRHEA; FEMALE; GLUCOSE; HUMANS; HYDROGEN; INTESTINE, SMALL; IRRITABLE BOWEL SYNDROME; LACTULOSE; MALE; METHANE; MICROBIOLOGICAL TECHNIQUES; MICROBIOTA; MIDDLE AGED; SENSITIVITY AND SPECIFICITY; YOUNG ADULT;

EID: 84902299464     PISSN: 0954691X     EISSN: 14735687     Source Type: Journal    
DOI: 10.1097/MEG.0000000000000122     Document Type: Article

References (39)

1. Ballou SK, Keefer L. Multicultural considerations in the diagnosis and management of irritable bowel syndrome: a selective summary. Eur J Gastroenterol Hepatol 2013; 25:1127-1133.
2. Gonzales Gamarra RG, Ruiz Sanchez JG, Leon Jimenez F, León Jiménez F, Cubas Benavides F, Díaz Vélez C. Prevalence of irritable bowel syndrome in the adult population of the city of Chiclayo in 2011. Rev Gastroenterol Peru 2012; 32:381-386.
3. Gwee KA, Lu CL, Ghoshal UC. Epidemiology of irritable bowel syndrome in Asia: something old, something new, something borrowed. J Gastroenterol Hepatol 2009; 24:1601-1607.
4. Krogsgaard LR, Engsbro AL, Bytzer P. The epidemiology of irritable bowel syndrome in Denmark. A population-based survey in adults ≤50 years of age. Scand J Gastroenterol 2013; 48:523-529.
5. Ibrahim NK, Battarjee WF, Almehmadi SA. Prevalence and predictors of irritable bowel syndrome among medical students and interns in King Abdulaziz University, Jeddah. Libyan J Med 2013; 8:21287.
6. Lee YY, Waid A, Tan HJ, Chua AS, Whitehead WE. Rome III survey of irritable bowel syndrome among ethnic Malays. World J Gastroenterol 2012; 18:6475-6480.
7. Ghoshal UC, Abraham P, Bhatt C, Choudhuri G, Bhatia SJ, Shenoy KT, et al. Epidemiological and clinical profile of irritable bowel syndrome in India: report of the Indian Society of Gastroenterology Task Force. Indian J Gastroenterol 2008; 27:22-28.
8. Bures J, Cyrany J, Kohoutova D, Förstl M, Rejchrt S, Kvetina J, et al. Small intestinal bacterial overgrowth syndrome. World J Gastroenterol 2010; 16:2978-2990.
9. Dibaise JK, Young RJ, Vanderhoof JA. Enteric microbial flora, bacterial overgrowth, and short-bowel syndrome. Clin Gastroenterol Hepatol 2006; 4:11-20.
10. Bouhnik Y, Alain S, Attar A, Flourié B, Raskine L, Sanson-Le Pors MJ, Rambaud JC. Bacterial populations contaminating the upper gut in patients with small intestinal bacterial overgrowth syndrome. Am J Gastroenterol 1999; 94:1327-1331.
11. Longstreth GF, Thompson WG, Chey WD, Houghton LA, Mearin F, Spiller RC. Functional bowel disorders. Gastroenterology 2006; 130:1480-1491.
12. Ghoshal UC, Shukla R, Ghoshal U, Gwee KA, Ng SC, Quigley EM. The gut microbiota and irritable bowel syndrome: friend or foe? Int J Inflam 2012; 2012:151085.
13. Posserud I, Stotzer PO, Bjornsson ES, Abrahamsson H, Simrén M. Small intestinal bacterial overgrowth in patients with irritable bowel syndrome. Gut 2007; 56:802-808.
14. Carrara M, Desideri S, Azzurro M, Bulighin GM, Di Piramo D, Lomonaco L, Adamo S. Small intestine bacterial overgrowth in patients with irritable bowel syndrome. Eur Rev Med Pharmacol Sci 2008; 12:197-202.
15. Sachdeva S, Rawat AK, Reddy RS. Small intestinal bacterial overgrowth (SIBO) in irritable bowel syndrome: frequency and predictors. J Gastroenterol Hepatol 2011; 26 (Suppl 3):S135-S138.
16. Park H. The role of small intestinal bacterial overgrowth in the pathophysiology of irritable bowel syndrome. J Neurogastroenterol Motil 2010; 16:3-4.
17. Pyleris E, Giamarellos-Bourboulis EJ, Tzivras D, Koussoulas V, Barbatzas C, Pimentel M. The prevalence of overgrowth by aerobic bacteria in the small intestine by small bowel culture: relationship with irritable bowel syndrome. Dig Dis Sci 2012; 57:1321-1329.
18. Pimentel M, Chow EJ, Lin HC. Eradication of small intestinal bacterial overgrowth reduces symptoms of irritable bowel syndrome. Am J Gastroenterol 2000; 95:3503-3506.
19. Park JS, Yu JH, Lim HC, Kim JH, Yoon YH, Park HJ, Lee SI. Usefulness of lactulose breath test for the prediction of small intestinal bacterial overgrowth in irritable bowel syndrome. Korean J Gastroenterol 2010; 56:242-248.
20. Ghoshal UC, Ghoshal U, Ayyagari A, Ranjan P, Krishnani N, Misra A, et al. Tropical sprue is associated with contamination of small bowel with aerobic bacteria and reversible prolongation of orocecal transit time. J Gastroenterol Hepatol 2003; 18:540-547.
21. Lu CL, Chen CY, Chang FY, Lee SD. Characteristics of small bowel motility in patients with irritable bowel syndrome and normal humans: an Oriental study. Clin Sci (Lond) 1998; 95:165-169.
22. Sciarretta G, Furno A, Mazzoni M, Garagnani B, Malaguti P. Lactulose hydrogen breath test in orocecal transit assessment. Critical evaluation by means of scintigraphic method. Dig Dis Sci 1994; 39:1505-1510.
23. Rao SS, Camilleri M, Hasler WL, Maurer AH, Parkman HP, Saad R, et al. Evaluation of gastrointestinal transit in clinical practice: position paper of the American and European Neurogastroenterology and Motility Societies. Neurogastroenterol Motil 2011; 23:8-23.
24. Yu D, Cheeseman F, Vanner S. Combined oro-caecal scintigraphy and lactulose hydrogen breath testing demonstrate that breath testing detects oro-caecal transit, not small intestinal bacterial overgrowth in patients with IBS. Gut 2011; 60:334-340.
25. Ghoshal UC, Ghoshal U, Das K, Misra A. Utility of hydrogen breath tests in diagnosis of small intestinal bacterial overgrowth in malabsorption syndrome and its relationship with oro-cecal transit time. Indian J Gastroenterol 2006; 25:6-10.
26. Ghoshal UC. How to interpret hydrogen breath tests. J Neurogastroenterol Motil 2011; 17:312-317.
27. Ghoshal UC, Kumar S, Mehrotra M, Lakshmi C, Misra A. Frequency of small intestinal bacterial overgrowth in patients with irritable bowel syndrome and chronic non-specific diarrhea. J Neurogastroenterol Motil 2010; 16:40-46.
28. Lombardo L, Foti M, Ruggia O, Chiecchio A. Increased incidence of small intestinal bacterial overgrowth during proton pump inhibitor therapy. Clin Gastroenterol Hepatol 2010; 8:504-508.
29. Parodi A, Dulbecco P, Savarino E, Giannini EG, Bodini G, Corbo M, et al. Positive glucose breath testing is more prevalent in patients with IBS-like symptoms compared with controls of similar age and gender distribution. J Clin Gastroenterol 2009; 43:962-966.
30. Rana SV, Sinha SK, Sikander A, Bhasin DK, Singh K. Study of small intestinal bacterial overgrowth in North Indian patients with irritable bowel syndrome: a case control study. Trop Gastroenterol 2008; 29:23-25.
31. Yang CY, Chang CS, Chen GH. Small-intestinal bacterial overgrowth in patients with liver cirrhosis, diagnosed with glucose H2 or CH4 breath tests. Scand J Gastroenterol 1998; 33:867-871.
32. Rana SV, Sharma S, Sinha SK, Kaur H, Sikander A, Singh K. Incidence of predominant methanogenic flora in irritable bowel syndrome patients and apparently healthy controls from North India. Dig Dis Sci 2009; 54:132-135.
33. Hattori T, Fukudo S. Use of Rome III criteria for diagnosing irritable bowel syndrome. Nihon Rinsho 2006; 64:1425-1428.
34. Ghoshal U, Ghoshal UC, Ranjan P, Naik SR, Ayyagari A. Spectrum and antibiotic sensitivity of bacteria contaminating the upper gut in patients with malabsorption syndrome from the tropics. BMC Gastroenterol 2003; 3:9.
35. Pimentel M, Wallace D, Hallegua D, Chow E, Kong Y, Park S, Lin HC. A link between irritable bowel syndrome and fibromyalgia may be related to findings on lactulose breath testing. Ann Rheum Dis 2004; 63:450-452.
36. Jang SI, Kim JH, Youn YH, Park H, Lee SI, Conklin JL. Relationship between intestinal gas and the development of right colonic diverticula. J Neurogastroenterol Motil 2010; 16:418-423.
37. Hamilton I, Worsley BW, Cobden I, Cooke EM, Shoesmith JG, Axon AT. Simultaneous culture of saliva and jejunal aspirate in the investigation of small bowel bacterial overgrowth. Gut 1982; 23:847-853.
38. Bala L, Ghoshal UC, Ghoshal U, Tripathi P, Misra A, Gowda GA, Khetrapal CL. Malabsorption syndrome with and without small intestinal bacterial overgrowth: a study on upper-gut aspirate using 1H NMR spectroscopy. Magn Reson Med 2006; 56:738-744.
39. Yakoob J, Abbas Z, Khan R, Hamid S, Awan S, Jafri W. Small intestinal bacterial overgrowth and lactose intolerance contribute to irritable bowel syndrome symptomatology in Pakistan. Saudi J Gastroenterol 2011; 17:371-375.