Are glycans the holy grail for biomarkers of aging? (Comment on: Glycans Are a Novel Biomarker of Chronological and Biological Age by Kristic et al.)

Journals of Gerontology - Series A Biological Sciences and Medical Sciences

Volumn 69, Issue 7, 2014, Pages 777-778

  Le Couteur, David G ^a   Simpson, Stephen J ^a   De Cabo, Rafael ^b  

^a UNIVERSITY OF SYDNEY   (Australia)

^b National Institute on Aging   (United States)

Author keywords

Biomarkers of aging; Glycans

Indexed keywords

IMMUNOGLOBULIN G; POLYSACCHARIDE;

AGING; BIOMARKERS OF AGING; CHEMISTRY; FEMALE; GLYCANS.; HUMAN; MALE; METABOLISM; NOTE;

BIOMARKERS OF AGING; GLYCANS.;

AGING; FEMALE; HUMANS; IMMUNOGLOBULIN G; MALE; POLYSACCHARIDES;

EID: 84902282170     PISSN: 10795006     EISSN: 1758535X     Source Type: Journal    
DOI: 10.1093/gerona/glt202     Document Type: Article

References (13)

1. Ingram DK, Nakamura E, Smucny D, Roth GS, Lane MA. Strategy for identifying biomarkers of aging in long-lived species. Exp Gerontol. 2001;36:1025-1034. (Pubitemid 32515218
2. Le Couteur DG, McLachlan AJ, Quinn RJ, Simpson SJ, de Cabo R. Aging biology and novel targets for drug discovery. J Gerontol A Biol Sci Med Sci. 2012;67:169-174
3. Johnson TE. Recent results: Biomarkers of aging. Exp Gerontol. 2006;41:1243-1246. (Pubitemid 44848393
4. Sprott RL. Biomarkers of aging and disease: Introduction and definitions. Exp Gerontol. 2010;45:2-4
5. Butler RN, Sprott RL. Biomarkers of aging: From primitive organisms to man. New York: International Longevity Center; 2000
6. Simm A, Johnson TE. Biomarkers of ageing: A challenge for the future. Exp Gerontol. 2010;45:731-732
7. Holly AC, Melzer D, Pilling LC, et al. Towards a gene expression biomarker set for human biological age. Aging Cell. 2013;12:324-326
8. V aldes AM, Glass D, Spector TD. Omics technologies and the study of human ageing. Nat Rev Genet. 2013;14:601-607
9. V anhooren V, Dewaele S, Libert C, et al. Serum N-glycan profile shift during human ageing. Exp Gerontol. 2010;45:738-743
10. Dall'Olio F, Vanhooren V, Chen CC, Slagboom PE, Wuhrer M, Franceschi C. N-glycomic biomarkers of biological aging and longevity: A link with inflammaging. Ageing Res Rev. 2013;12:685-698
11. Krištić J, Vučković F, Menni C, et al. Glycans are a novel biomarker of chronological and biological age. J Gerontol A Biol Sci Med Sci. In press
12. Parekh R, Roitt I, Isenberg D, Dwek R, Rademacher T. Age-related galactosylation of the N-linked oligosaccharides of human serum IgG. J Exp Med. 1988;167:1731-1736
13. Franceschi C, Capri M, Monti D, et al. Inflammaging and anti-inflammaging: A systemic perspective on aging and longevity emerged from studies in humans. Mech Ageing Dev. 2007;128:92-105. (Pubitemid 46073065.