Augmentation pressure is influenced by ventricular contractility/relaxation dynamics novel mechanism of reduction of pulse pressure by nitrates

Hypertension

Volumn 63, Issue 5, 2014, Pages 1050-1055

  Fok, Henry ^a   Guilcher, Antoine ^a   Li, Ye ^a   Brett, Sally ^a   Shah, Ajay ^a   Clapp, Brian ^a   Chowienczyk, Phil ^a  

^a ST THOMAS HOSPITAL   (United Kingdom)

Author keywords

Pulse wave analysis

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; GLYCERYL TRINITRATE; NITRIC ACID DERIVATIVE;

ADULT; AGED; AMPLITUDE MODULATION; AORTA FLOW; AORTA PRESSURE; ARTICLE; AUGMENTATION INDEX; AUGMENTATION PRESSURE; BLOOD PRESSURE MEASUREMENT; CLINICAL ARTICLE; DRUG EFFICACY; FEMALE; HEART CATHETERIZATION; HEART HEMODYNAMICS; HEART VENTRICLE; HEART VENTRICLE CONTRACTION; HEART VENTRICLE EJECTION; HUMAN; MALE; MIDDLE AGED; PRIORITY JOURNAL; PULSE PRESSURE; PULSE WAVE; RISK REDUCTION; SYSTOLIC HYPERTENSION;

PULSE WAVE ANALYSIS;

ADULT; AGED; ARTERIAL PRESSURE; BLOOD PRESSURE; CARDIAC CATHETERIZATION; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HEMODYNAMICS; HUMANS; MALE; MIDDLE AGED; MUSCLE RELAXATION; MYOCARDIAL CONTRACTION; NITRATES; NITROGLYCERIN; PULSE WAVE ANALYSIS; REGIONAL BLOOD FLOW; STROKE VOLUME; VENTRICULAR FUNCTION;

EID: 84902279358     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.113.02955     Document Type: Article

References (29)

1. Roman MJ, Devereux RB, Kizer J.R., Lee ET, Galloway JM, Ali T, Umans J.G., Howard BV. Central pressure more strongly relates to vascular disease and outcome than does brachial pressure: the Strong Heart Study. Hypertension. 2007; 50: 197-203. (Pubitemid 46986041)
2. Vlachopoulos C, Aznaouridis K, O'Rourke MF, Safar ME, Baou K, Stefanadis C. Prediction of cardiovascular events and all-cause mortality with central haemodynamics: a systematic review and meta-analysis. Eur Heart J. 2010; 31: 1865-1871.
3. Williams B, Lacy PS, Thom S.M., Cruickshank K., Stanton A, Collier D, Hughes A.D., Thurston H., O'Rourke M; CAFE Investigators; Anglo-Scandinavian Cardiac Outcomes Trial Investigators; CAFE Steering Committee and Writing Committee. Differential impact of blood pressure-lowering drugs on central aortic pressure and clinical outcomes: principal results of the Conduit Artery Function Evaluation (CAFE) study. Circulation. 2006; 113: 1213-1225.
4. Westerhof N, Sipkema P, van den Bos GC, Elzinga G. Forward and backward waves in the arterial system. Cardiovasc Res. 1972; 6: 648-656.
5. Nichols WW, O'Rourke MF. McDonald's Blood Flow in Arteries. Theoretical, Experimental and clinical principles. London: Arnold; 1998.
6. O'Rourke M.F., Pauca AL Augmentation of the aortic and central arterial pressure waveform. Blood Press Monit. 2004; 9: 179-185. (Pubitemid 39159160)
7. Segers P, Rietzschel ER, de Buyzere ML, de Bacquer D, van Bortel LM, de Backer G, Gillebert TC, Verdonck PR. Assessment of pressure wave reflection: getting the timing right! Physiol Meas. 2007; 28: 1045-1056. (Pubitemid 47304370)
8. Hughes AD, Park C, Davies J., Francis D, McG Thom SA, Mayet J, Parker KH. Limitations of augmentation index in the assessment of wave reflection in normotensive healthy individuals. PLoS One. 2013; 8:e59371.
9. Yaginuma T, Avolio A, O'Rourke M, Nichols W, Morgan J.J., Roy P., Baron D, Branson J, Feneley M. Effect of glyceryl trinitrate on peripheral arteries alters left ventricular hydraulic load in man. Cardiovasc Res. 1986; 20: 153-160. (Pubitemid 16165842)
10. Kelly RP, Gibbs HH, O'Rourke MF, Daley JE, Mang K, Morgan J.J., Avolio AP. Nitroglycerin has more favourable effects on left ventricular afterload than apparent from measurement of pressure in a peripheral artery. Eur Heart J. 1990; 11: 138-144. (Pubitemid 20095698)
11. Pauca AL, Kon ND, O'Rourke MF. Benefit of glyceryl trinitrate on arterial stiffness is directly due to effects on peripheral arteries. Heart. 2005; 91: 1428-1432. (Pubitemid 41531816)
12. Layland J, Li JM, Shah AM Role of cyclic GMP-dependent protein kinase in the contractile response to exogenous nitric oxide in rat cardiac myocytes. J Physiol. 2002; 540(Pt 2): 457-467. (Pubitemid 35190124)
13. Paulus WJ, Vantrimpont PJ, Shah AM Acute effects of nitric oxide on left ventricular relaxation and diastolic distensibility in humans. Assessment by bicoronary sodium nitroprusside infusion. Circulation. 1994; 89: 2070-2078. (Pubitemid 24142783)
14. Parker KH. An introduction to wave intensity analysis. Med Biol Eng Comput. 2009; 47: 175-188.
15. Penny DJ, Mynard JP, Smolich JJ Aortic wave intensity analysis of ventricular-vascular interaction during incremental dobutamine infusion in adult sheep. Am J Physiol Heart Circ Physiol. 2008; 294:H481-H489.
16. Fok H, Jiang B, Clapp B., Chowienczyk P. Regulation of vascular tone and pulse wave velocity in human muscular conduit arteries: selective effects of nitric oxide donors to dilate muscular arteries relative to resistance vessels. Hypertension. 2012; 60: 1220-1225.
17. Davies JE, Whinnett ZI, Francis D.P., Willson K., Foale RA, Malik IS, Hughes AD, Parker K.H., Mayet J. Use of simultaneous pressure and velocity measurements to estimate arterial wave speed at a single site in humans. Am J Physiol Heart Circ Physiol. 2006; 290:H878-H885.
18. Hughes AD, Parker KH Forward and backward waves in the arterial system: impedance or wave intensity analysis? Med Biol Eng Comput. 2009; 47: 207-210.
19. Cecelja M, Jiang B, McNeill K., Kato B, Ritter J, Spector T., Chowienczyk P. Increased wave reflection rather than central arterial stiffness is the main determinant of raised pulse pressure in women and relates to mismatch in arterial dimensions: a twin study. J Am Coll Cardiol. 2009; 54: 695-703.
20. Cecelja M, Jiang B, Spector T.D., Chowienczyk P. Progression of central pulse pressure over 1 decade of aging and its reversal by nitroglycerin a twin study. J Am Coll Cardiol. 2012; 59: 475-483.
21. Ayer JG, Harmer JA, David C, S Steinbeck K, Seale JP, Celermajer DS Severe obesity is associated with impaired arterial smooth muscle function in young adults. Obesity (Silver Spring). 2011; 19: 54-60.
22. Latson TW, Hunter WC, Katoh N, Sagawa K. Effect of nitroglyc-erin on aortic impedance, diameter, and pulse-wave velocity. Circ Res. 1988; 62: 884-890.
23. Chirinos JA, Segers P, Gupta A.K., Swillens A., Rietzschel ER, de Buyzere ML, Kirkpatrick JN, Gillebert TC, Wang Y, Keane MG, Townsend R, Ferrari VA, Wiegers SE, St John Sutton M. Time-varying myocardial stress and systolic pressure-stress relationship: role in myocardial-arterial coupling in hypertension. Circulation. 2009; 119: 2798-2807.
24. Shah AM, Spurgeon HA, Sollott S.J., Talo A., Lakatta EG 8-bromo-cGMP reduces the myofilament response to Ca2+ in intact cardiac myocytes. Circ Res. 1994; 74: 970-978.
25. Noonan PK, Benet LZ Incomplete and delayed bioavailability of sublingual nitroglycerin. Am J Cardiol. 1985; 55: 184-187. (Pubitemid 15152548)
26. Schultz MG, Davies JE, Roberts-Thomson P, Black J.A., Hughes AD, Sharman JE Exercise central (aortic) blood pressure is predominantly driven by forward traveling waves, not wave reflection. Hypertension. 2013; 62: 175-182.
27. Borlaug BA, Melenovsky V, Redfield M.M., Kessler K., Chang HJ, Abraham TP, Kass DA Impact of arterial load and loading sequence on left ventricular tissue velocities in humans. J Am Coll Cardiol. 2007; 50: 1570-1577. (Pubitemid 47532334)
28. Seddon M, Shah AM, Casadei B. Cardiomyocytes as effectors of nitric oxide signalling. Cardiovasc Res. 2007; 75: 315-326. (Pubitemid 46961933)
29. Lakatta EG. Arterial and Cardiac Aging: Major Shareholders in Cardiovascular Disease Enterprises. Circulation 2003; 107: 490-497.