The role of opioid prescription in incident opioid abuse and dependence among individuals with chronic noncancer pain: The role of opioid prescription

Clinical Journal of Pain

Volumn 30, Issue 7, 2014, Pages 557-564

  Edlund, Mark J ^a   Martin, Bradley C ^b   Russo, Joan E ^c   Devries, Andrea ^d   Braden, Jennifer B ^c   Sullivan, Mark D ^c  

^a RTI INTERNATIONAL   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^d HEALTHCORE INC   (United States)

Author keywords

opioid abuse; opioid prescription; prescription drug abuse; substance abuse

Indexed keywords

ACETYLSALICYLIC ACID; CODEINE; CODEINE SULFATE; DEXTROPROPOXYPHENE; DIHYDROCODEINE; FENTANYL; FENTANYL CITRATE; HYDROMORPHONE; IBUPROFEN; LEVORPHANOL; METHADONE; MORPHINE; MORPHINE SULFATE; OPIATE; OXYCODONE; OXYMORPHONE; PARACETAMOL; PENTAZOCINE; PETHIDINE; NARCOTIC ANALGESIC AGENT; PRESCRIPTION DRUG;

ADULT; AGED; ARTICLE; CHRONIC NONCANCER PAIN; CHRONIC PAIN; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG EXPOSURE; DRUG MEGADOSE; DRUG USE; FEMALE; HUMAN; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; MENTAL HEALTH; OPIATE ADDICTION; PRESCRIPTION; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR; TREATMENT DURATION; ADOLESCENT; DOSE RESPONSE; FACTUAL DATABASE; INCIDENCE; MIDDLE AGED; OPIOID-RELATED DISORDERS; OUTCOME ASSESSMENT; STATISTICS AND NUMERICAL DATA; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; ANALGESICS, OPIOID; CHRONIC PAIN; DATABASES, FACTUAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; INCIDENCE; MALE; MIDDLE AGED; OPIOID-RELATED DISORDERS; OUTCOME ASSESSMENT (HEALTH CARE); PRESCRIPTION DRUGS; YOUNG ADULT;

EID: 84902268204     PISSN: 07498047     EISSN: 15365409     Source Type: Journal    
DOI: 10.1097/AJP.0000000000000021     Document Type: Article

References (42)

1. Gilson AM, Ryan KM, Joranson DE, et al. A reassessment of trends in the medical use and abuse of opioid analgesics and implications for diversion control: 1997-2002. J Pain Symptom Manage. 2004;28:176-188.
2. Gureje O, Von Korff M, Simon GE, et al. Persistent pain and well-being: A World Health Organization study in primary care. JAMA. 1998;280:147-151.
3. Sullivan MD, Edlund MJ, Fan MY, et al. Trends in use of opioids for non-cancer pain conditions 2000-2005 in Commercial and Medicaid insurance plans: the TROUP study. Pain. 2008;138:440-449.
4. Zacny J, Bigelow G, Compton P, et al. College on Problems of Drug Dependence taskforce on prescription opioid nonmedical use and abuse: position statement. Drug Alcohol Depend. 2003;69:215-232.
5. Portenoy RK, Foley KM. Chronic use of opioid analgesics in non-malignant pain: report of 38 cases. Pain. 1986;25:171-186.
6. Chou R, Fanciullo GJ, Fine PG, et al. Clinical guidelines for the use of chronic opioid therapy in chronic noncancer pain. J Pain. 2009;10:113-130.
7. American Geriatrics Society. Pharmacological management of persistent pain in older persons. J Am Geriatr Soc. 2009;57: 1331-1346.
8. Federation of State Medical Boards of The United States. Model guidelines for the use of controlled substances for the treatment of pain. S D J Med. 1999;52:25-27.
9. Federation of State Medical Boards of The United States. Model policy for the use of controlled substances for the treatment of pain. J Pain Palliat Care Pharmacother. 2005;19: 73-78.
10. Compton WM, Volkow ND. Major increases in opioid analgesic abuse in the United States: concerns and strategies. Drug Alcohol Depend. 2006;81:103-107.
11. Paulozzi LJ, Budnitz DS, Xi Y. Increasing deaths from opioid analgesics in the United States. Pharmacoepidemiol Drug Saf. 2006;15:618-627.
12. Paulozzi LJ, Xi Y. Recent changes in drug poisoning mortality in the United States by urban-rural status and by drug type. Pharmacoepidemiol Drug Saf. 2008;17:997-1005.
13. Substance Abuse Mental Health Services Administration. Office of Applied Studies: Summary of Findings from the 2000 National Household Survey on Drug Abuse. Rockville, MD: Department of Health and Human Services; 2000.
14. Warner M, Chen LH, Makuc DM. Increase in fatal poisonings involving opioid analgesics in the United States, 1999-2006. NCHS Data Brief, no 22. Hyattsville, MD: US Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Health Statistics; 2009.
15. Fishbain DA, Cole B, Lewis J, et al. What percentage of chronic nonmalignant pain patients exposed to chronic opioid analgesic therapy develop abuse/addiction and/or aberrant drug-related behaviors? A structured evidence-based review. Pain Med. 2008;9:444-459.
16. Boscarino JA, Rukstalis M, Hoffman SN, et al. Risk factors for drug dependence among out-patients on opioid therapy in a large US health-care system. Addiction. 2010;105: 1776-1782.
17. Becker WC, Sullivan LE, Tetrault JM, et al. Non-medical use, abuse and dependence on prescription opioids among US adults: psychiatric, medical and substance use correlates. Drug Alcohol Depend. 2008;94:38-47.
18. Edlund MJ, Martin BC, Fan MY, et al. Risks for opioid abuse and dependence among recipients of chronic opioid therapy: results from the TROUP study. Drug Alcohol Depend. 2010;1: 90-98.
19. Edlund MJ, Steffick D, Hudson T, et al. Risk factors for clinically recognized opioid abuse and dependence among veterans using opioids for chronic non-cancer pain. Pain. 2007;129:355-362.
20. Braden JB, Fan MY, Edlund MJ, et al. Trends in use of opioids by noncancer pain type 2000-2005 among Arkansas Medicaid and HealthCore Enrollees: results from the TROUP study. J Pain. 2010;9:1026-1035.
21. Washington State Agency Medical Directors Group. Interagency guideline on opioid dosing for chronic non-cancer pain: an educational pilot to improve care and safety with opioid treatment, 2007. Available from http://www. agencymeddirectors. wa.gov/opioiddosing.asp. Last accessed October 2, 2013.
22. Morasco BJ, Duckart JP, Dobscha SK. Adherence to clinical guidelines for opioid therapy for chronic pain in patients with substance use disorder. J Gen Intern Med. 2011;26:965-971.
23. Von Korff M, Saunders K, Ray GT, et al. De facto long-Term opioid therapy for non-cancer pain. Clin J Pain. 2008;24: 521-527.
24. American Pain Society. Principles of Analgesic Use in the Treatment of Acute Pain and Cancer Pain. 5th ed. Glenview, IL: American Pain Society; 2003.
25. Fine P, Portenoy RK. A Clinical Guide to Opioid Analgesia. Minneapolis: McGraw-Hill Healthcare Information; 2004.
26. Vieweg WV, Lipps WF, Fernandez A. Opioids and methadone equivalents for clinicians. Prim Care Companion J Clin Psychiatry. 2005;7:86-88.
27. Agency for Health Care Research and Quality. Clinical Classifications Software (CCS) for ICD-9-CM. [Web site]. Available at: http://www.hcup-us.ahrq. gov/toolssoftware/ccs/ccs.jsp Accessed November 7, 2009.
28. Charlson ME, Pompei P, Ales KL, et al. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40:373-383.
29. Merlin JS, Westfall AO, Raper JL, et al. Pain, mood, and substance abuse in HIV: implications for clinic visit utilization, antiretroviral therapy adherence, and virologic failure. J Acquir Immune Defic Syndr. 2012;61:164-170.
30. Edlund MJ, Martin BC, Fan MY, et al. An analysis of heavy utilizers of opioids for non-cancer pain conditions in the TROUP study. J Pain Symptom Manage. 2010;40:279-289.
31. Martell BA, OConnor PG, Kerns RD, et al. Systematic review: opioid treatment for chronic back pain: prevalence, efficacy, and association with addiction. Ann Intern Med. 2007;146:116-127.
32. Braden JB, Russo J, Fan MY, et al. Emergency department visits among recipients of chronic opioid therapy. Arch Intern Med. 2010;170:1425-1432.
33. Dunn KM, Saunders KW, Rutter CM, et al. Opioid prescriptions for chronic pain and overdose: a cohort study. Ann Intern Med. 2010;152:85-92.
34. Saunders KW, Dunn KM, Merrill JO, et al. Relationship of opioid use and dosage levels to fractures in older chronic pain patients. J Gen Intern Med. 2010;25:310-315.
35. Sullivan MD, Edlund MJ, Fan MY, et al. Risks for possible and probable opioid misuse among recipients of chronic opioid therapy in commerical and medicaid insurance plans: the TROUP study. Pain. 2010;150:332-339.
36. Cook RJ, Sackett DL. The number needed to treat: a clinically useful measure of treatment effect. BMJ. 1995;310:452-454.
37. Noble M, Tregear SJ, Treadwell JR, et al. Long-Term opioid therapy for chronic noncancer pain: a systematic review and meta-Analysis of efficacy and safety. J Pain Symptom Manage. 2008;35:214-228.
38. Morasco BJ, Duckart JP, Carr TP, et al. Clinical characteristics of veterans prescribed high doses of opioid medications for chronic non-cancer pain. Pain. 2010;151:625-632.
39. Martin BC, Fan MY, Edlund MJ, et al. Long-Term chronic opioid therapy discontinuation rates from the TROUP study. J Gen Intern Med. 2011;26:1450-1457.
40. Annemans L. Pharmacoeconomic impact of adverse events of long-Term opioid treatment for the management of persistent pain. Clin Drug Investig. 2011;31:73-86.
41. Papaleontiou M, Henderson CR Jr, Turner BJ, et al. Outcomes associated with opioid use in the treatment of chronic noncancer pain in older adults: a systematic review and meta-Analysis. J Am Geriatr Soc. 2010;58:1353-1369.
42. Centers for Disease Control and Prevention. Morbidity and mortality weekly report: vital signs: overdoses of prescription opioid pain relievers-United States, 1999-2008; 2011.