메뉴 건너뛰기




Volumn 37, Issue 6, 2014, Pages 355-362

Soft tissue sarcoma: An update on systemic treatment options for patients with advanced disease

Author keywords

Advanced disease; Chemotherapy; Metastasis; Soft tissue sarcoma; Targeted agents

Indexed keywords

CYTOTOXIC AGENT; DACARBAZINE; DOCETAXEL; DOXORUBICIN; GEMCITABINE; IFOSFAMIDE; PALIFOSFAMIDE; PAZOPANIB; TRABECTEDIN; 1,3 DIOXOLANE DERIVATIVE; ANTINEOPLASTIC AGENT; PYRIMIDINE DERIVATIVE; SULFONAMIDE; TETRAHYDROISOQUINOLINE DERIVATIVE; PACLITAXEL;

EID: 84902256995     PISSN: 22965270     EISSN: None     Source Type: Journal    
DOI: 10.1159/000362631     Document Type: Review
Times cited : (87)

References (38)
  • 2
    • 77954337682 scopus 로고    scopus 로고
    • Soft tissue sarcomas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
    • ESMO/CONTICANET/ EUROBONET consensus panel of experts
    • Casali PG, Blay JY; ESMO/CONTICANET/ EUROBONET consensus panel of experts: Soft tissue sarcomas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 2010;21 Suppl 5:v198-203.
    • (2010) Ann Oncol , vol.21 , Issue.SUPPL. 5
    • Casali, P.G.1    Blay, J.Y.2
  • 3
    • 84872678571 scopus 로고    scopus 로고
    • Descriptive epidemiology of sarcomas in Europe: Report from the RARECARE project
    • Stiller CA, Trama A, Serraino D, et al.: Descriptive epidemiology of sarcomas in Europe: Report from the RARECARE project. Eur J Cancer 2013;49: 684-695.
    • (2013) Eur J Cancer , vol.49 , pp. 684-695
    • Stiller, C.A.1    Trama, A.2    Serraino, D.3
  • 4
    • 7644224728 scopus 로고    scopus 로고
    • Validation of the postoperative nomogram for 12-year sarcoma-specific mortality
    • Eilber FC, Brennan MF, Eilber FR, et al.: Validation of the postoperative nomogram for 12-year sarcoma-specific mortality. Cancer 2004;101:2270-2275.
    • (2004) Cancer , vol.101 , pp. 2270-2275
    • Eilber, F.C.1    Brennan, M.F.2    Eilber, F.R.3
  • 5
    • 0141615691 scopus 로고    scopus 로고
    • Prognostic factors for disease-specific survival after first relapse of soft-tissue sarcoma. Analysis of 402 patients with disease relapse after initial conservative surgery and radiotherapy
    • Zagars GK, Ballo MT, Pisters PW, et al. Prognostic factors for disease-specific survival after first relapse of soft-tissue sarcoma: Analysis of 402 patients with disease relapse after initial conservative surgery and radiotherapy. Int J Radiat Oncol Biol Phys 2003;57:739-747.
    • (2003) Int J Radiat Oncol Biol Phys , vol.57 , pp. 739-747
    • Zagars, G.K.1    Ballo, M.T.2    Pisters, P.W.3
  • 6
    • 84897031194 scopus 로고    scopus 로고
    • Doxorubicin alone versus intensified doxorubicin plus ifosfamide for first-line treatment of advanced or metastatic soft-tissue sarcoma: A randomised controlled phase 3 trial
    • Judson I, Verweij J, Gelderblom H, et al.: Doxorubicin alone versus intensified doxorubicin plus ifosfamide for first-line treatment of advanced or metastatic soft-tissue sarcoma: A randomised controlled phase 3 trial. Lancet Oncol 2014; 15:415-423.
    • (2014) Lancet Oncol , vol.15 , pp. 415-423
    • Judson, I.1    Verweij, J.2    Gelderblom, H.3
  • 7
    • 77953494126 scopus 로고    scopus 로고
    • Neo-adjuvant chemotherapy alone or with regional hyperthermia for localised high-risk soft-tissue sarcoma: A randomised phase 3 multicentre study
    • Issels RD, Lindner LH, Verweij J, et al.: Neo-adjuvant chemotherapy alone or with regional hyperthermia for localised high-risk soft-tissue sarcoma: A randomised phase 3 multicentre study. Lancet Oncol 2010;11:561-570.
    • (2010) Lancet Oncol , vol.11 , pp. 561-570
    • Issels, R.D.1    Lindner, L.H.2    Verweij, J.3
  • 8
    • 0029087491 scopus 로고
    • Adjuvant chemotherapy for soft-tissue sarcoma: Review and meta-analysis of the published results of randomised clinical trials
    • Tierney JF, Mosseri V, Stewart LA, et al.: Adjuvant chemotherapy for soft-tissue sarcoma: Review and meta-analysis of the published results of randomised clinical trials. Br J Cancer 1995;72:469-475.
    • (1995) Br J Cancer , vol.72 , pp. 469-475
    • Tierney, J.F.1    Mosseri, V.2    Stewart, L.A.3
  • 9
    • 49049089340 scopus 로고    scopus 로고
    • A systematic meta-analysis of randomized controlled trials of adjuvant chemotherapy for localized resectable soft-tissue sarcoma
    • Pervaiz N, Colterjohn N, Farrokhyar F, et al.: A systematic meta-analysis of randomized controlled trials of adjuvant chemotherapy for localized resectable soft-tissue sarcoma. Cancer 2008;13:573-581.
    • (2008) Cancer , vol.13 , pp. 573-581
    • Pervaiz, N.1    Colterjohn, N.2    Farrokhyar, F.3
  • 10
    • 41149169284 scopus 로고    scopus 로고
    • Significant clinical benefit of first-line palliative chemotherapy in advanced soft-tissue sarcoma: Retro-spective analysis and identification of prognostic factors in 488 patients
    • Karavasilis V, Seddon BM, Ashley S, et al.: Significant clinical benefit of first-line palliative chemotherapy in advanced soft-tissue sarcoma: retro-spective analysis and identification of prognostic factors in 488 patients. Cancer 2008;112:1585-1591.
    • (2008) Cancer , vol.112 , pp. 1585-1591
    • Karavasilis, V.1    Seddon, B.M.2    Ashley, S.3
  • 11
    • 77953502245 scopus 로고    scopus 로고
    • Guidelines for the management of soft tissue sarcomas
    • Grimer R, Judson I, Peake D, Seddon B: Guidelines for the management of soft tissue sarcomas. Sarcoma 2010;2010:506182.
    • (2010) Sarcoma , vol.2010 , pp. 506182
    • Grimer, R.1    Judson, I.2    Peake, D.3    Seddon, B.4
  • 12
    • 0029005580 scopus 로고
    • Doxorubicin versus CYVADIC versus doxorubicin plus ifosfamide in first-line treatment of advanced soft tissue sarcomas: A randomized study of the European Organization for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group
    • Santoro A, Tursz T, Mouridsen H, et al.: Doxorubicin versus CYVADIC versus doxorubicin plus ifosfamide in first-line treatment of advanced soft tissue sarcomas: A randomized study of the European Organization for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group. J Clin Oncol 1995;13:1537-1545.
    • (1995) J Clin Oncol , vol.13 , pp. 1537-1545
    • Santoro, A.1    Tursz, T.2    Mouridsen, H.3
  • 13
    • 80155134726 scopus 로고    scopus 로고
    • Pulmonary resection of metastatic sarcoma: Prognostic factors associated with improved outcomes
    • Kim S, Ott HC, Wright CD, et al.: Pulmonary resection of metastatic sarcoma: Prognostic factors associated with improved outcomes. Ann Thorac Surg 2011;92:1780-1786.
    • (2011) Ann Thorac Surg , vol.92 , pp. 1780-1786
    • Kim, S.1    Ott, H.C.2    Wright, C.D.3
  • 14
    • 84866525946 scopus 로고    scopus 로고
    • Randomized multicenter and stratified phase II study of gemcitabine alone versus gemcitabine and docetaxel in patients with metastatic or relapsed leiomyosarcomas: A Federation Nationale des Centres de Lutte Contre le Cancer (FNCLCC) French Sarcoma Group Study (TAXOGEM study)
    • Pautier P, Floquet A, Penel N, et al.: Randomized multicenter and stratified phase II study of gemcitabine alone versus gemcitabine and docetaxel in patients with metastatic or relapsed leiomyosarcomas: A Federation Nationale des Centres de Lutte Contre le Cancer (FNCLCC) French Sarcoma Group Study (TAXOGEM study). Oncologist 2012;17:1213-1220.
    • (2012) Oncologist , vol.17 , pp. 1213-1220
    • Pautier, P.1    Floquet, A.2    Penel, N.3
  • 15
    • 0031812631 scopus 로고    scopus 로고
    • A phase II study of docetaxel in chemotherapy naïve patients with recurrent or metastatic adult soft tissue sarcoma
    • Bramwell V, Blackstein M, Belanger K, et al.: A phase II study of docetaxel in chemotherapynaïve patients with recurrent or metastatic adult soft tissue sarcoma. Sarcoma 1998;2:29-33.
    • (1998) Sarcoma , vol.2 , pp. 29-33
    • Bramwell, V.1    Blackstein, M.2    Belanger, K.3
  • 16
    • 54449099288 scopus 로고    scopus 로고
    • Paclitaxel in patients with advanced angiosarcomas of soft tissue: A retrospective study of the EORTC soft tissue and bone sarcoma group
    • Schlemmer M, Reichardt P, Verweij J, et al.: Paclitaxel in patients with advanced angiosarcomas of soft tissue: A retrospective study of the EORTC soft tissue and bone sarcoma group. Eur J Cancer 2008;44:2433-2436.
    • (2008) Eur J Cancer , vol.44 , pp. 2433-2436
    • Schlemmer, M.1    Reichardt, P.2    Verweij, J.3
  • 17
    • 84887088076 scopus 로고    scopus 로고
    • Antitumor antibiotics
    • Perry MC (ed.): Lippincott Williams and Wilkins
    • Riggs CE: Antitumor antibiotics; in Perry MC (ed.): The chemotherapy sourcebook. Lippincott Williams and Wilkins, 2001, pp. 231-234.
    • (2001) The Chemotherapy Sourcebook , pp. 231-234
    • Riggs, C.E.1
  • 18
    • 34547688913 scopus 로고    scopus 로고
    • Phase III trial of two investigational schedules of ifosfamide compared with standard-dose doxorubicin in advanced or metastatic soft tissue sarcoma: A European Organisation for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group Study
    • Lorigan P, Verweij J, Papai Z, et al.: Phase III trial of two investigational schedules of ifosfamide compared with standard-dose doxorubicin in advanced or metastatic soft tissue sarcoma: A European Organisation for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group Study. J Clin Oncol 2007;25:3144-3150.
    • (2007) J Clin Oncol , vol.25 , pp. 3144-3150
    • Lorigan, P.1    Verweij, J.2    Papai, Z.3
  • 19
    • 58149335531 scopus 로고    scopus 로고
    • American Society of Clinical Oncology 2008 cliniretrocal practice guideline update: Use of chemotherapy and radiation therapy protectants
    • Hensley M, Hagerty K, Kewalramani T, et al.: American Society of Clinical Oncology 2008 cliniretrocal practice guideline update: Use of chemotherapy and radiation therapy protectants. J Clin Oncol 2008;27:127-145.
    • (2008) J Clin Oncol , vol.27 , pp. 127-145
    • Hensley, M.1    Hagerty, K.2    Kewalramani, T.3
  • 20
    • 0036892122 scopus 로고    scopus 로고
    • Results of randomised studies of the EORTC Soft Tissue and Bone Sarcoma Group (STBSG) with two different ifosfamide regimens in first-and second-line chemotherapy in advanced soft tissue sarcoma patients
    • Van Oosterom AT, Mouridsen HT, Nielsen OS, et al.: Results of randomised studies of the EORTC Soft Tissue and Bone Sarcoma Group (STBSG) with two different ifosfamide regimens in first-and second-line chemotherapy in advanced soft tissue sarcoma patients. Eur J Cancer 2002;38:2397-2406.
    • (2002) Eur J Cancer , vol.38 , pp. 2397-2406
    • Van Oosterom, A.T.1    Mouridsen, H.T.2    Nielsen, O.S.3
  • 21
    • 84894061172 scopus 로고    scopus 로고
    • International expert opinion on patient-tailored management of soft tissue sarcomas
    • Blay JY, Sleijfer S, Schöffski P, et al.: International expert opinion on patient-tailored management of soft tissue sarcomas. Eur J Cancer 2014;50:679-689.
    • (2014) Eur J Cancer , vol.50 , pp. 679-689
    • Blay, J.Y.1    Sleijfer, S.2    Schöffski, P.3
  • 22
    • 46749092063 scopus 로고    scopus 로고
    • Clinical impact of trabectedin (ecteinascidin-743) in advanced/ metastatic soft tissue sarcoma
    • Schöffski P, Dumez H, Wolter P, et al.: Clinical impact of trabectedin (ecteinascidin-743) in advanced/ metastatic soft tissue sarcoma. Expert Opin Pharmacother 2008;9:1609-1618.
    • (2008) Expert Opin Pharmacother , vol.9 , pp. 1609-1618
    • Schöffski, P.1    Dumez, H.2    Wolter, P.3
  • 23
    • 84856855321 scopus 로고    scopus 로고
    • Administration of 24-h intravenous infusions of trabectedin in ambulatory patients with mesenchymal tumors via disposable elastomeric pumps: An effective and patient-friendly palliative treatment option
    • Schöffski P, Cerbone L, Wolter P, et al.: Administration of 24-h intravenous infusions of trabectedin in ambulatory patients with mesenchymal tumors via disposable elastomeric pumps: An effective and patient-friendly palliative treatment option. Onkologie 2012;35:14-17.
    • (2012) Onkologie , vol.35 , pp. 14-17
    • Schöffski, P.1    Cerbone, L.2    Wolter, P.3
  • 24
    • 79953706562 scopus 로고    scopus 로고
    • Predictive impact of DNA repair functionality on clinical outcome of advanced sarcoma patients treated with trabectedin: A retrospective multicentric study
    • Schöffski P, Taron M, Jimeno J, et al.: Predictive impact of DNA repair functionality on clinical outcome of advanced sarcoma patients treated with trabectedin: A retrospective multicentric study. Eur J Cancer. 2011;47:1006-1012.
    • (2011) Eur J Cancer. , vol.47 , pp. 1006-1012
    • Schöffski, P.1    Taron, M.2    Jimeno, J.3
  • 25
    • 78651354407 scopus 로고    scopus 로고
    • Trabectedin (T) in advanced, pretreated synovial sarcomas (SS): A retrospective analysis of 39 patients (pts) from three European institutions. 2010 ASCO Annual Meeting Abstracts
    • abstract 10030
    • Dileo O, Sanfilippo R, Grosso F, et al.: Trabectedin (T) in advanced, pretreated synovial sarcomas (SS): A retrospective analysis of 39 patients (pts) from three European institutions. 2010 ASCO Annual Meeting Abstracts. J Clin Oncol 2010;28: No. 7S (abstract 10030).
    • (2010) J Clin Oncol , vol.28 , Issue.7 S
    • Dileo, O.1    Sanfilippo, R.2    Grosso, F.3
  • 26
    • 70249101414 scopus 로고    scopus 로고
    • Efficacy and safety of trabectedin in patients with advanced or metastatic liposarcoma or leiomyosarcoma after failure of prior anthracyclines and ifosfamide: Results of a randomized phase II study of two different schedules
    • Demetri GD, Chawla SP, Von Mehren M, et al.: Efficacy and safety of trabectedin in patients with advanced or metastatic liposarcoma or leiomyosarcoma after failure of prior anthracyclines and ifosfamide: Results of a randomized phase II study of two different schedules. J Clin Oncol 2009;27: 4188-4196.
    • (2009) J Clin Oncol , vol.27 , pp. 4188-4196
    • Demetri, G.D.1    Chawla, S.P.2    Von Mehren, M.3
  • 27
    • 34447572873 scopus 로고    scopus 로고
    • Randomized phase II study of gemcitabine and docetaxel compared with gemcitabine alone in patients with metastatic soft tissue sarcomas: Results of sarcoma alliance for research through collaboration study 002
    • Erratum in: J Clin Oncol 2007;25:3790
    • Maki RG, Wathen JK, Patel SR, et al.: Randomized phase II study of gemcitabine and docetaxel compared with gemcitabine alone in patients with metastatic soft tissue sarcomas: Results of sarcoma alliance for research through collaboration study 002. J Clin Oncol 2007;25:2755-2763. Erratum in: J Clin Oncol 2007;25:3790.
    • (2007) J Clin Oncol , vol.25 , pp. 2755-2763
    • Maki, R.G.1    Wathen, J.K.2    Patel, S.R.3
  • 28
    • 79959300987 scopus 로고    scopus 로고
    • Randomized phase II study comparing gemcitabine plus dacarbazine alone in patients with previously treated soft tissue sarcoma: A Spanish Group for Research on Sarcomas Study
    • Garcia-del-Muro X, López-Pousa A, Maurel J, et al.: Randomized phase II study comparing gemcitabine plus dacarbazine alone in patients with previously treated soft tissue sarcoma: A Spanish Group for Research on Sarcomas Study. J Clin Oncol 2011;29:2528-2533.
    • (2011) J Clin Oncol , vol.29 , pp. 2528-2533
    • Garcia-Del-Muro, X.1    López-Pousa, A.2    Maurel, J.3
  • 29
    • 14244262491 scopus 로고    scopus 로고
    • Covalent DNA-binding drugs
    • Perry MC (ed.): Lippincott Williams and Wilkins
    • Grochow LB: Covalent DNA-binding drugs; in Perry MC (ed.): The chemotherapy sourcebook. Lippincott Williams and Wilkins, 2001, pp. 196-197.
    • (2001) The Chemotherapy Sourcebook , pp. 196-197
    • Grochow, L.B.1
  • 30
    • 34547867058 scopus 로고    scopus 로고
    • Trabectedin (ET-743): Evaluation of its use in advanced softtissue sarcoma
    • Schöffski P, Wolter P, Clement P, et al.: Trabectedin (ET-743): Evaluation of its use in advanced softtissue sarcoma. Future Oncol 2007;3:381-392.
    • (2007) Future Oncol , vol.3 , pp. 381-392
    • Schöffski, P.1    Wolter, P.2    Clement, P.3
  • 31
    • 84855214329 scopus 로고    scopus 로고
    • Anticancer activity of stabilized palifosfamide in vivo: Schedule effects, oral bioavailability, and enhanced activity with docetaxel and doxorubicin
    • Jones B, Komarnitsky P, Miller GT, et al.: Anticancer activity of stabilized palifosfamide in vivo: Schedule effects, oral bioavailability, and enhanced activity with docetaxel and doxorubicin. Anticancer Drugs 2012;23:173-184.
    • (2012) Anticancer Drugs , vol.23 , pp. 173-184
    • Jones, B.1    Komarnitsky, P.2    Miller, G.T.3
  • 32
    • 84863786833 scopus 로고    scopus 로고
    • TH-302, a hypoxia-activated prodrug with broad in vivo preclinical combination therapy efficacy: Optimization of dosing regimens and schedules
    • Liu Q, Sun JD, Wang J, Ahluwalia D, et al.: TH-302, a hypoxia-activated prodrug with broad in vivo preclinical combination therapy efficacy: Optimization of dosing regimens and schedules. Cancer Chemother Pharmacol 2012;69:1487-1498.
    • (2012) Cancer Chemother Pharmacol , vol.69 , pp. 1487-1498
    • Liu, Q.1    Sun, J.D.2    Wang, J.3    Ahluwalia, D.4
  • 33
    • 84902251367 scopus 로고    scopus 로고
    • A phase 3 multicenter, international, randomized, doubleblind, placebo-controlled study of doxorubicin plus palifosfamide vs. Doxorubicin plus placebo in patients with front-line metastatic soft tissue sarcoma
    • Amsterdam
    • Ryan CW, Schöffski P, Merimsky O, et al.: A phase 3 multicenter, international, randomized, doubleblind, placebo-controlled study of doxorubicin plus palifosfamide vs. doxorubicin plus placebo in patients with front-line metastatic soft tissue sarcoma. ECCO Congress 2013, Amsterdam.
    • (2013) ECCO Congress
    • Ryan, C.W.1    Schöffski, P.2    Merimsky, O.3
  • 34
    • 80053383254 scopus 로고    scopus 로고
    • Activity of eribulin mesylate in patients with soft-tissue sarcoma: A phase 2 study in four independent histological subtypes
    • Schöffski P, Ray-Coquard IL, Cioffi A, et al.: Activity of eribulin mesylate in patients with soft-tissue sarcoma: A phase 2 study in four independent histological subtypes. Lancet Oncol 2011;12:1045-1052.
    • (2011) Lancet Oncol , vol.12 , pp. 1045-1052
    • Schöffski, P.1    Ray-Coquard, I.L.2    Cioffi, A.3
  • 35
    • 67449164582 scopus 로고    scopus 로고
    • Phase i trial of pazopanib in patients with advanced cancer
    • Hurwitz HI, Dowlati A, Saini S, et al.: Phase I trial of pazopanib in patients with advanced cancer. Clin Cancer Res 2009;15:4220-4227.
    • (2009) Clin Cancer Res , vol.15 , pp. 4220-4227
    • Hurwitz, H.I.1    Dowlati, A.2    Saini, S.3
  • 36
    • 67650337802 scopus 로고    scopus 로고
    • Pazopanib, a multikinase angiogenesis inhibitor, in patients with relapsed or refractory advanced soft tissue sarcoma: A phase II study from the European Organisation for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group (EORTC study 62043)
    • Sleijfer S, Ray-Coquard I, Papai Z, et al.: Pazopanib, a multikinase angiogenesis inhibitor, in patients with relapsed or refractory advanced soft tissue sarcoma: A phase II study from the European Organisation for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group (EORTC study 62043). J Clin Oncol 2009;27:3126-3132.
    • (2009) J Clin Oncol , vol.27 , pp. 3126-3132
    • Sleijfer, S.1    Ray-Coquard, I.2    Papai, Z.3
  • 37
    • 84861098484 scopus 로고    scopus 로고
    • Pazopanib for metastatic soft-tissue sarcoma (PALETTE): A randomised, double-blind, placebo-controlled phase 3 trial
    • Van der Graaf WT, Blay JY, Chawla SP, et al.: Pazopanib for metastatic soft-tissue sarcoma (PALETTE): A randomised, double-blind, placebo-controlled phase 3 trial. Lancet 2012;379: 1879-1886.
    • (2012) Lancet , vol.379 , pp. 1879-1886
    • Van Der Graaf, W.T.1    Blay, J.Y.2    Chawla, S.P.3
  • 38
    • 84866603440 scopus 로고    scopus 로고
    • ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
    • The ESMO/European Sarcoma Network Working Group. Soft tissue and visceral sarcomas
    • The ESMO/European Sarcoma Network Working Group. Soft tissue and visceral sarcomas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 2012;23 (Suppl 7):vii92-99.
    • (2012) Ann Oncol , vol.23 , Issue.SUPPL. 7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.