H2S and its role in redox signaling

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1844, Issue 8, 2014, Pages 1355-1366

  Kabil, Omer ^a   Motl, Nicole ^a   Banerjee, Ruma ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Hydrogen sulfide; Redox; Thiol

Indexed keywords

ELECTROPHILE; HYDROGEN SULFIDE; ION CHANNEL; S NITROSOTHIOL; SULFIDE; SULFUR; THIOL;

ANIMAL; APOPTOSIS; BIOCHEMISTRY; BIOENERGY; BIOGENESIS; BLOOD PRESSURE; CELL ENERGY; CELL FUNCTION; DISEASES; ENDOPLASMIC RETICULUM; ENZYMOLOGY; GASTROINTESTINAL TRACT; HEALTH; HEART FUNCTION; HUMAN; HYPOXIA; INFLAMMATION; METABOLISM; MITOCHONDRION; NEUROMODULATION; NONHUMAN; OXIDATION REDUCTION REACTION; PHYSIOLOGICAL PROCESS; PRIORITY JOURNAL; REDOX; REVIEW; SIGNAL TRANSDUCTION; STRESS; TISSUE LEVEL; VASODILATATION;

HYDROGEN SULFIDE; REDOX; THIOL;

ANIMALS; CELL PHYSIOLOGICAL PHENOMENA; HUMANS; HYDROGEN SULFIDE; METABOLISM; OXIDATION-REDUCTION; SIGNAL TRANSDUCTION;

EID: 84902255282     PISSN: 15709639     EISSN: 18781454     Source Type: Journal    
DOI: 10.1016/j.bbapap.2014.01.002     Document Type: Review

References (216)

1. N. Brandes, S. Schmitt, and U. Jakob Thiol-based redox switches in eukaryotic proteins Antioxid. Redox Signal. 11 2009 997 1014
2. K. Abe, and H. Kimura The possible role of hydrogen sulfide as an endogenous neuromodulator J. Neurosci. 16 1996 1066 1071 (Pubitemid 26140863)
3. B.D. Paul, and S.H. Snyder H(2)S signalling through protein sulfhydration and beyond Nat. Rev. Mol. Cell Biol. 13 2012 499 507
4. J. Pan, and K.S. Carroll Persulfide reactivity in the detection of protein S-sulfhydration ACS Chem. Biol. 8 6 2013 1110 1116
5. T. Chiku, D. Padovani, W. Zhu, S. Singh, V. Vitvitsky, and R. Banerjee H2S biogenesis by human cystathionine gamma-lyase leads to the novel sulfur metabolites lanthionine and homolanthionine and is responsive to the grade of hyperhomocysteinemia J. Biol. Chem. 284 2009 11601 11612
6. 2S biogenesis via alternative trans-sulfuration reactions J. Biol. Chem. 284 2009 22457 22466
7. A. Meister, P.E. Fraser, and S.V. Tice Enzymatic desulfuration of beta-mercaptopyruvate to pyruvate J. Biol. Chem. 206 1954 561 575
8. N. Shibuya, Y. Mikami, Y. Kimura, N. Nagahara, and H. Kimura Vascular endothelium expresses 3-mercaptopyruvate sulfurtransferase and produces hydrogen sulfide J. Biochem. 146 2009 623 626
9. P.W. Beatty, and D.J. Reed Involvement of the cystathionine pathway in the biosynthesis of glutathione by isolated rat hepatocytes Arch. Biochem. Biophys. 204 1980 80 87 (Pubitemid 11186356)
10. E. Mosharov, M.R. Cranford, and R. Banerjee The quantitatively important relationship between homocysteine metabolism and glutathione synthesis by the transsulfuration pathway and its regulation by redox changes Biochemistry 39 2000 13005 13011
11. V. Vitvitsky, O. Kabil, and R. Banerjee High turnover rates for hydrogen sulfide allow for rapid regulation of its tissue concentrations Antioxid. Redox Signal. 17 2012 22 31
12. T. Ubuka, S. Umemura, S. Yuasa, M. Kinuta, and K. Watanabe Purification and characterization of mitochondrial cysteine aminotransferase from rat liver Physiol. Chem. Phys. 10 1978 483 500
13. G.D. Westrop, I. Georg, and G.H. Coombs The mercaptopyruvate sulfurtransferase of Trichomonas vaginalis links cysteine catabolism to the production of thioredoxin persulfide J. Biol. Chem. 284 2009 33485 33494
14. P.K. Yadav, K. Yamada, T. Chiku, M. Koutmos, and R. Banerjee Structure and kinetic analysis of H2S production by human mercaptopyruvate sulfurtransferase J. Biol. Chem. 288 2013 20002 20013
15. Y. Mikami, N. Shibuya, Y. Kimura, N. Nagahara, Y. Ogasawara, and H. Kimura Thioredoxin and dihydrolipoic acid are required for 3-mercaptopyruvate sulfurtransferase to produce hydrogen sulfide Biochem. J. 439 2011 479 485
16. O. Kabil, V. Vitvitsky, P. Xie, and R. Banerjee The quantitative significance of the transsulfuration enzymes for H2S production in murine tissues Antioxid. Redox Signal. 15 2011 363 372
17. Y. Ogasawara, S. Isoda, and S. Tanabe Tissue and subcellular distribution of bound and acid-labile sulfur, and the enzymic capacity for sulfide production in the rat Biol. Pharm. Bull. 17 1994 1535 1542
18. 2S as a physiologic vasorelaxant: hypertension in mice with deletion of cystathionine gamma-lyase Science 322 2008 587 590
19. N. Nagahara, T. Ito, H. Kitamura, and T. Nishino Tissue and subcellular distribution of mercaptopyruvate sulfurtransferase in the rat: confocal laser fluorescence and immunoelectron microscopic studies combined with biochemical analysis Histochem. Cell Biol. 110 1998 243 250 (Pubitemid 28401732)
20. N. Shibuya, M. Tanaka, M. Yoshida, Y. Ogasawara, T. Togawa, K. Ishii, and H. Kimura 3-Mercaptopyruvate sulfurtransferase produces hydrogen sulfide and bound sulfane sulfur in the brain Antioxid. Redox Signal. 11 2009 703 714
21. 2S biogenesis Biochim. Biophys. Acta 1814 2011 1518 1527
22. 2S biogenesis, decay and signaling Antioxid. Redox Signal. 2013 (Epub ahead of print)
23. N. Motl, P.K. Yadav, and R. Banerjee Enzymology of hydrogen sulfide turnover H. Kimura, Hydrogen Sulfide and its Therapeutic Applications 2013 Springer
24. V. Vitvitsky, S. Dayal, S. Stabler, Y. Zhou, H. Wang, S.R. Lentz, and R. Banerjee Perturbations in homocysteine-linked redox homeostasis in a murine model for hyperhomocysteinemia Am. J. Physiol. Regul. Integr. Comp. Physiol. 287 2004 R39 R46
25. N. Tateishi, T. Higashi, S. Shinya, A. Naruse, and Y. Sakamoto Studies on the regulation of glutathione level in rat liver J. Biochem. 75 1974 93 103
26. I. Ueki, H.B. Roman, L.L. Hirschberger, C. Junior, and M.H. Stipanuk Extrahepatic tissues compensate for loss of hepatic taurine synthesis in mice with liver-specific knockout of cysteine dioxygenase Am. J. Physiol. Endocrinol. Metab. 302 2012 E1292 E1299
27. V. Vitvitsky, S.K. Garg, and R. Banerjee Taurine biosynthesis by neurons and astrocytes J. Biol. Chem. 286 2011 32002 32010
28. M.H. Stipanuk, J.E. Dominy Jr., J.I. Lee, and R.M. Coloso Mammalian cysteine metabolism: new insights into regulation of cysteine metabolism J. Nutr. 136 2006 1652S 1659S (Pubitemid 43765376)
29. P.K. Yadav, P. Xie, and R. Banerjee Allosteric communication between the pyridoxal 5′-phosphate (PLP) and heme sites in the H2S generator human cystathionine beta-synthase J. Biol. Chem. 287 2012 37611 37620
30. J. Furne, A. Saeed, and M.D. Levitt Whole tissue hydrogen sulfide concentrations are orders of magnitude lower than presently accepted values Am. J. Physiol. Regul. Integr. Comp. Physiol. 295 2008 R1479 R1485
31. N.L. Whitfield, E.L. Kreimier, F.C. Verdial, N. Skovgaard, and K.R. Olson Reappraisal of H2S/sulfide concentration in vertebrate blood and its potential significance in ischemic preconditioning and vascular signaling Am. J. Physiol. Regul. Integr. Comp. Physiol. 294 2008 R1930 R1937
32. M.D. Levitt, M.S. Abdel-Rehim, and J. Furne Free and acid-labile hydrogen sulfide concentrations in mouse tissues: anomalously high free hydrogen sulfide in aortic tissue Antioxid. Redox Signal. 15 2011 373 378
33. C.G. Curtis, T.C. Bartholomew, F.A. Rose, and K.S. Dodgson Detoxication of sodium 35 S-sulphide in the rat Biochem. Pharmacol. 21 1972 2313 2321
34. T.C. Bartholomew, G.M. Powell, K.S. Dodgson, and C.G. Curtis Oxidation of sodium sulphide by rat liver, lungs and kidney Biochem. Pharmacol. 29 1980 2431 2437 (Pubitemid 10048525)
35. M.A. Powell, and G.N. Somero Hydrogen sulfide oxidation is coupled to oxidative phosphorylation in mitochondria of Solemya reidi Science 233 1986 563 566
36. T.M. Hildebrandt, and M.K. Grieshaber Three enzymatic activities catalyze the oxidation of sulfide to thiosulfate in mammalian and invertebrate mitochondria FEBS J. 275 2008 3352 3361 (Pubitemid 351813547)
37. R.O. Beauchamp Jr., J.S. Bus, J.A. Popp, C.J. Boreiko, and D.A. Andjelkovich A critical review of the literature on hydrogen sulfide toxicity Crit. Rev. Toxicol. 13 1984 25 97 (Pubitemid 14069476)
38. M.M. Cherney, Y. Zhang, M. Solomonson, J.H. Weiner, and M.N. James Crystal structure of sulfide:quinone oxidoreductase from Acidithiobacillus ferrooxidans: insights into sulfidotrophic respiration and detoxification J. Mol. Biol. 398 2010 292 305
39. M.R. Jackson, S.L. Melideo, and M.S. Jorns Human sulfide:quinone oxidoreductase catalyzes the first step in hydrogen sulfide metabolism and produces a sulfane sulfur metabolite Biochemistry 51 2012 6804 6815
40. V. Tiranti, C. Viscomi, T. Hildebrandt, I. Di Meo, R. Mineri, C. Tiveron, M.D. Levitt, A. Prelle, G. Fagiolari, M. Rimoldi, and M. Zeviani Loss of ETHE1, a mitochondrial dioxygenase, causes fatal sulfide toxicity in ethylmalonic encephalopathy Nat. Med. 15 2009 200 205
41. T.P. Singer, and E.B. Kearney Intermediary metabolism of L-cysteinesulfinic acid in animal tissues Arch. Biochem. Biophys. 61 1956 397 409
42. M.H. Stipanuk Metabolism of sulfur-containing amino acids Annu. Rev. Nutr. 6 1986 179 209
43. J.E. Dominy Jr., L.L. Hirschberger, R.M. Coloso, and M.H. Stipanuk In vivo regulation of cysteine dioxygenase via the ubiquitin-26S proteasome system Adv. Exp. Med. Biol. 583 2006 37 47
44. C. Viscomi, A.B. Burlina, I. Dweikat, M. Savoiardo, C. Lamperti, T. Hildebrandt, V. Tiranti, and M. Zeviani Combined treatment with oral metronidazole and N-acetylcysteine is effective in ethylmalonic encephalopathy Nat. Med. 16 2010 869 871
45. H. Beinert, R.H. Holm, and E. Munck Iron-sulfur clusters: nature's modular, multipurpose structures Science 277 1997 653 659 (Pubitemid 27373905)
46. M. Ishigami, K. Hiraki, K. Umemura, Y. Ogasawara, K. Ishii, and H. Kimura A source of hydrogen sulfide and a mechanism of its release in the brain Antioxid. Redox Signal. 11 2009 205 214
47. Z. Srebro, and A. Slebodzinski Periventricular Gomori-positive glia in the hypothalamus of the rabbit Folia Biol. 14 1966 391 395
48. M. Iciek, A. Bilska, L. Ksiazek, Z. Srebro, and L. Wlodek Allyl disulfide as donor and cyanide as acceptor of sulfane sulfur in the mouse tissues Pharmacol. Rep. 57 2005 212 218 (Pubitemid 40778712)
49. V.S. Vorobets, S.K. Kovach, and G.Y. Kolbasov Russ. J. Appl. Chem. 75 2002 229 234
50. J.C. Mathai, A. Missner, P. Kugler, S.M. Saparov, M.L. Zeidel, J.K. Lee, and P. Pohl No facilitator required for membrane transport of hydrogen sulfide Proc. Natl. Acad. Sci. U. S. A. 106 2009 16633 16638
51. T. Rohwerder, and W. Sand The sulfane sulfur of persulfides is the actual substrate of the sulfur-oxidizing enzymes from Acidithiobacillus and Acidiphilium spp. Microbiology 149 2003 1699 1710
52. J.I. Toohey Sulphane sulphur in biological systems: a possible regulatory role Biochem. J. 264 1989 625 632 (Pubitemid 20023429)
53. J.P. Collman, S. Ghosh, A. Dey, and R.A. Decreau Using a functional enzyme model to understand the chemistry behind hydrogen sulfide induced hibernation Proc. Natl. Acad. Sci. U. S. A. 106 2009 22090 22095
54. Y. Kimura, and H. Kimura Hydrogen sulfide protects neurons from oxidative stress FASEB J. 18 2004 1165 1167 (Pubitemid 39561558)
55. Y. Kimura, R. Dargusch, D. Schubert, and H. Kimura Hydrogen sulfide protects HT22 neuronal cells from oxidative stress Antioxid. Redox Signal. 8 2006 661 670 (Pubitemid 43741334)
56. D. Yonezawa, F. Sekiguchi, M. Miyamoto, E. Taniguchi, M. Honjo, T. Masuko, H. Nishikawa, and A. Kawabata A protective role of hydrogen sulfide against oxidative stress in rat gastric mucosal epithelium Toxicology 241 2007 11 18 (Pubitemid 47599777)
57. Z. Fu, X. Liu, B. Geng, L. Fang, and C. Tang Hydrogen sulfide protects rat lung from ischemia-reperfusion injury Life Sci. 82 2008 1196 1202
58. S. Jha, J.W. Calvert, M.R. Duranski, A. Ramachandran, and D.J. Lefer Hydrogen sulfide attenuates hepatic ischemia-reperfusion injury: role of antioxidant and antiapoptotic signaling Am. J. Physiol. Heart Circ. Physiol. 295 2008 H801 H806
59. M. Whiteman, N.S. Cheung, Y.Z. Zhu, S.H. Chu, J.L. Siau, B.S. Wong, J.S. Armstrong, and P.K. Moore Hydrogen sulphide: a novel inhibitor of hypochlorous acid-mediated oxidative damage in the brain? Biochem. Biophys. Res. Commun. 326 2005 794 798 (Pubitemid 39655989)
60. M. Whiteman, J.S. Armstrong, S.H. Chu, S. Jia-Ling, B.S. Wong, N.S. Cheung, B. Halliwell, and P.K. Moore The novel neuromodulator hydrogen sulfide: an endogenous peroxynitrite 'scavenger'? J. Neurochem. 90 2004 765 768 (Pubitemid 38989409)
61. M. Whiteman, L. Li, I. Kostetski, S.H. Chu, J.L. Siau, M. Bhatia, and P.K. Moore Evidence for the formation of a novel nitrosothiol from the gaseous mediators nitric oxide and hydrogen sulphide Biochem. Biophys. Res. Commun. 343 2006 303 310
62. M.Y. Ali, C.Y. Ping, Y.Y. Mok, L. Ling, M. Whiteman, M. Bhatia, and P.K. Moore Regulation of vascular nitric oxide in vitro and in vivo; a new role for endogenous hydrogen sulphide? Br. J. Pharmacol. 149 2006 625 634 (Pubitemid 44748055)
63. P. Nagy, and C.C. Winterbourn Rapid reaction of hydrogen sulfide with the neutrophil oxidant hypochlorous acid to generate polysulfides Chem. Res. Toxicol. 23 2010 1541 1543
64. S. Carballal, M. Trujillo, E. Cuevasanta, S. Bartesaghi, M.N. Moller, L.K. Folkes, M.A. Garcia-Bereguiain, C. Gutierrez-Merino, P. Wardman, A. Denicola, R. Radi, and B. Alvarez Reactivity of hydrogen sulfide with peroxynitrite and other oxidants of biological interest Free Radic. Biol. Med. 50 2011 196 205
65. M.R. Filipovic, J. Miljkovic, A. Allgauer, R. Chaurio, T. Shubina, M. Herrmann, and I. Ivanovic-Burmazovic Biochemical insight into physiological effects of H(2)S: reaction with peroxynitrite and formation of a new nitric oxide donor, sulfinyl nitrite Biochem. J. 441 2012 609 621
66. P. Wardman, and C. von Sonntag Kinetic factors that control the fate of thiyl radicals in cells Methods Enzymol. 251 1995 31 45
67. - in aqueous solutions J. Phys. Chem. A 103 1999 5221 5226
68. G. Mills, K.H. Schmidt, M.S. Matheson, and D. Meisel Thermal and photochemical reactions of sulfhydryl radicals: implications for colloid photocorrosion J. Phys. Chem. 91 1987 1590 1596
69. 2- and HSS J. Phys. Chem. 95 1991 3676 3681
70. A. Stasko, V. Brezova, M. Zalibera, S. Biskupic, and K. Ondrias Electron transfer: a primary step in the reactions of sodium hydrosulphide, an H2S/HS(-) donor Free Radic. Res. 43 2009 581 593
71. N.E. Francoleon, S.J. Carrington, and J.M. Fukuto The reaction of H(2)S with oxidized thiols: generation of persulfides and implications to H(2)S biology Arch. Biochem. Biophys. 516 2011 146 153
72. S.D. Benson Thermochemistry and kinetics of sulfur-containing molecules and radicals Chem. Rev. 78 1978 23 25
73. S.A. Everett, L.K. Folkes, P. Wardman, and K.D. Asmus Free-radical repair by a novel perthiol: reversible hydrogen transfer and perthiyl radical formation Free Radic. Res. 20 1994 387 400 (Pubitemid 24170148)
74. G.L. Newton, T.J. Dwyer, T. Kim, J.F. Ward, and R.C. Fahey Determination of the acid dissociation constants for WR-1065 by proton NMR spectroscopy Radiat. Res. 131 1992 143 151
75. S.A. Everett, and P. Wardman Perthiols as antioxidants: radical-scavenging and prooxidative mechanisms Methods Enzymol. 251 1995 55 69
76. 2S and S-nitrosothiols J. Am. Chem. Soc. 134 2012 12016 12027
77. 2S signals through protein S-sulfhydration Sci. Signal. 2 2009 ra72
78. P. Nagy, and C.C. Winterbourn Rapid reaction of hydrogen sulfide with the neutrophil oxidant hypochlorous acid to generate polysulfides Chem. Res. Toxicol. 23 2010 1541 1543
79. 2S to protein thiol oxidation Antioxid. Redox Signal. 19 2013 1749 1765
80. V. Massey, and D. Edmondson On the mechanism of inactivation of xanthine oxidase by cyanide J. Biol. Chem. 245 1970 6595 6598
81. U. Branzoli, and V. Massey Evidence for an active site persulfide residue in rabbit liver aldehyde oxidase J. Biol. Chem. 249 1974 4346 4349
82. J.L. Hargrove Persulfide generated from L-cysteine inactivates tyrosine aminotransferase. Requirement for a protein with cysteine oxidase activity and gamma-cystathionase J. Biol. Chem. 263 1988 17262 17269
83. N. Krishnan, C. Fu, D.J. Pappin, and N.K. Tonks H2S-induced sulfhydration of the phosphatase PTP1B and its role in the endoplasmic reticulum stress response Sci. Signal. 4 2011 ra86
84. N. Sen, B.D. Paul, M.M. Gadalla, A.K. Mustafa, T. Sen, R. Xu, S. Kim, and S.H. Snyder Hydrogen sulfide-linked sulfhydration of NF-kappaB mediates its antiapoptotic actions Mol. Cell 45 2012 13 24
85. W. Zhao, J. Zhang, Y. Lu, and R. Wang The vasorelaxant effect of H(2)S as a novel endogenous gaseous K(ATP) channel opener EMBO J. 20 2001 6008 6016 (Pubitemid 33049276)
86. A.K. Mustafa, G. Sikka, S.K. Gazi, J. Steppan, S.M. Jung, A.K. Bhunia, V.M. Barodka, F.K. Gazi, R.K. Barrow, R. Wang, L.M. Amzel, D.E. Berkowitz, and S.H. Snyder Hydrogen sulfide as endothelium-derived hyperpolarizing factor sulfhydrates potassium channels Circ. Res. 109 2011 1259 1268
87. R. Hosoki, N. Matsuki, and H. Kimura The possible role of hydrogen sulfide as an endogenous smooth muscle relaxant in synergy with nitric oxide Biochem. Biophys. Res. Commun. 237 1997 527 531 (Pubitemid 27434718)
88. L. Li, A. Hsu, and P.K. Moore Actions and interactions of nitric oxide, carbon monoxide and hydrogen sulphide in the cardiovascular system and in inflammation - a tale of three gases! Pharmacol. Ther. 123 2009 386 400
89. C. Coletta, A. Papapetropoulos, K. Erdelyi, G. Olah, K. Modis, P. Panopoulos, A. Asimakopoulou, D. Gero, I. Sharina, E. Martin, and C. Szabo Hydrogen sulfide and nitric oxide are mutually dependent in the regulation of angiogenesis and endothelium-dependent vasorelaxation Proc. Natl. Acad. Sci. U. S. A. 109 2012 9161 9166
90. A. Fago, F.B. Jensen, B. Tota, M. Feelisch, K.R. Olson, S. Helbo, S. Lefevre, D. Mancardi, A. Palumbo, G.K. Sandvik, and N. Skovgaard Integrating nitric oxide, nitrite and hydrogen sulfide signaling in the physiological adaptations to hypoxia: a comparative approach Comp. Biochem. Physiol. A Mol. Integr. Physiol. 162 2012 1 6
91. B.L. Predmore, K. Kondo, S. Bhushan, M.A. Zlatopolsky, A.L. King, J.P. Aragon, D.B. Grinsfelder, M.E. Condit, and D.J. Lefer The polysulfide diallyl trisulfide protects the ischemic myocardium by preservation of endogenous hydrogen sulfide and increasing nitric oxide bioavailability Am. J. Physiol. Heart Circ. Physiol. 302 2012 H2410 H2418
92. Z. Tomaskova, A. Bertova, and K. Ondrias On the involvement of H2S in nitroso signaling and other mechanisms of H2S action Curr. Pharm. Biotechnol. 12 2011 1394 1405
93. Q.C. Yong, L.F. Hu, S. Wang, D. Huang, and J.S. Bian Hydrogen sulfide interacts with nitric oxide in the heart: possible involvement of nitroxyl Cardiovasc. Res. 88 2010 482 491
94. J.M. Fukuto, K. Chiang, R. Hszieh, P. Wong, and G. Chaudhuri The pharmacological activity of nitroxyl: a potent vasodilator with activity similar to nitric oxide and/or endothelium-derived relaxing factor J. Pharmacol. Exp. Ther. 263 1992 546 551
95. N. Paolocci, W.F. Saavedra, K.M. Miranda, C. Martignani, T. Isoda, J.M. Hare, M.G. Espey, J.M. Fukuto, M. Feelisch, D.A. Wink, and D.A. Kass Nitroxyl anion exerts redox-sensitive positive cardiac inotropy in vivo by calcitonin gene-related peptide signaling Proc. Natl. Acad. Sci. U. S. A. 98 2001 10463 10468 (Pubitemid 32803042)
96. T. Katori, D.B. Hoover, J.L. Ardell, R.H. Helm, D.F. Belardi, C.G. Tocchetti, P.R. Forfia, D.A. Kass, and N. Paolocci Calcitonin gene-related peptide in vivo positive inotropy is attributable to regional sympatho-stimulation and is blunted in congestive heart failure Circ. Res. 96 2005 234 243 (Pubitemid 40209371)
97. P.B. Massion, M. Pelat, C. Belge, and J.L. Balligand Regulation of the mammalian heart function by nitric oxide Comp. Biochem. Physiol. A Mol. Integr. Physiol. 142 2005 144 150 (Pubitemid 41443574)
98. W. Flores-Santana, D.J. Salmon, S. Donzelli, C.H. Switzer, D. Basudhar, L. Ridnour, R. Cheng, S.A. Glynn, N. Paolocci, J.M. Fukuto, K.M. Miranda, and D.A. Wink The specificity of nitroxyl chemistry is unique among nitrogen oxides in biological systems Antioxid. Redox Signal. 14 2011 1659 1674
99. S.P. Singh, J.S. Wishnok, M. Keshive, W.M. Deen, and S.R. Tannenbaum The chemistry of the S-nitrosoglutathione/glutathione system Proc. Natl. Acad. Sci. U. S. A. 93 1996 14428 14433 (Pubitemid 26418983)
100. P.S. Wong, J. Hyun, J.M. Fukuto, F.N. Shirota, E.G. DeMaster, D.W. Shoeman, and H.T. Nagasawa Reaction between S-nitrosothiols and thiols: generation of nitroxyl (HNO) and subsequent chemistry Biochemistry 37 1998 5362 5371 (Pubitemid 28241917)
101. D.R. Arnelle, and J.S. Stamler NO +, NO, and NO- donation by S-nitrosothiols: implications for regulation of physiological functions by S-nitrosylation and acceleration of disulfide formation Arch. Biochem. Biophys. 318 1995 279 285
102. Q.K. Timerghazin, G.H. Peslherbe, and A.M. English Resonance description of S-nitrosothiols: insights into reactivity Org. Lett. 9 2007 3049 3052
103. Q.K. Timerghazin, G.H. Peslherbe, and A.M. English Structure and stability of HSNO, the simplest S-nitrosothiol Phys. Chem. Chem. Phys. 10 2008 1532 1539
104. M.R. Filipovic, M. Eberhardt, V. Prokopovic, A. Mijuskovic, Z. Orescanin-Dusic, P. Reeh, and I. Ivanovic-Burmazovic Beyond H2S and NO interplay: hydrogen sulfide and nitroprusside react directly to give nitroxyl (HNO). A new pharmacological source of HNO J. Med. Chem. 56 2013 1499 1508
105. J.M. Fukuto, M.D. Bartberger, A.S. Dutton, N. Paolocci, D.A. Wink, and K.N. Houk The physiological chemistry and biological activity of nitroxyl (HNO): the neglected, misunderstood, and enigmatic nitrogen oxide Chem. Res. Toxicol. 18 2005 790 801 (Pubitemid 40705445)
106. J.C. Irvine, J.L. Favaloro, R.E. Widdop, and B.K. Kemp-Harper Nitroxyl anion donor, Angeli's salt, does not develop tolerance in rat isolated aortae Hypertension 49 2007 885 892 (Pubitemid 351664199)
107. M. Nishida, T. Sawa, N. Kitajima, K. Ono, H. Inoue, H. Ihara, H. Motohashi, M. Yamamoto, M. Suematsu, H. Kurose, A. van der Vliet, B.A. Freeman, T. Shibata, K. Uchida, Y. Kumagai, and T. Akaike Hydrogen sulfide anion regulates redox signaling via electrophile sulfhydration Nat. Chem. Biol. 8 2012 714 724
108. T.K. Rudolph, and B.A. Freeman Transduction of redox signaling by electrophile-protein reactions Sci. Signal. 2 2009 re7
109. K. Stamatakis, and D. Perez-Sala Prostanoids with cyclopentenone structure as tools for the characterization of electrophilic lipid-protein interactomes Ann. N. Y. Acad. Sci. 1091 2006 548 570 (Pubitemid 47092266)
110. H.J. Forman, J.M. Fukuto, and M. Torres Redox signaling: thiol chemistry defines which reactive oxygen and nitrogen species can act as second messengers Am. J. Physiol. Cell Physiol. 287 2004 C246 C256
111. K. Uchida, and T. Shibata 15-Deoxy-delta(12,14)-prostaglandin J2: an electrophilic trigger of cellular responses Chem. Res. Toxicol. 21 2008 138 144 (Pubitemid 351219715)
112. T. Sawa, M.H. Zaki, T. Okamoto, T. Akuta, Y. Tokutomi, S. Kim-Mitsuyama, H. Ihara, A. Kobayashi, M. Yamamoto, S. Fujii, H. Arimoto, and T. Akaike Protein S-guanylation by the biological signal 8-nitroguanosine 3′,5′- cyclic monophosphate Nat. Chem. Biol. 3 2007 727 735 (Pubitemid 47609113)
113. D.S. Bredt, P.M. Hwang, and S.H. Snyder Localization of nitric oxide synthase indicating a neural role for nitric oxide Nature 347 1990 768 770
114. E. Cernuda-Morollon, E. Pineda-Molina, F.J. Canada, and D. Perez-Sala 15-Deoxy-delta 12,14-prostaglandin J2 inhibition of NF-kappaB-DNA binding through covalent modification of the p50 subunit J. Biol. Chem. 276 2001 35530 35536
115. Y.G. Fu, J.J. Sung, K.C. Wu, A.H. Bai, M.C. Chan, J. Yu, D.M. Fan, and W.K. Leung Inhibition of gastric cancer cells associated angiogenesis by 15d-prostaglandin J2 through the downregulation of angiopoietin-1 Cancer Lett. 243 2006 246 254 (Pubitemid 44485851)
116. W.H. Cho, C.H. Choi, J.Y. Park, S.K. Kang, and Y.K. Kim 15-Deoxy-(delta12,14)-prostaglandin J2 (15d-PGJ2) induces cell death through caspase-independent mechanism in A172 human glioma cells Neurochem. Res. 31 2006 1247 1254 (Pubitemid 44701772)
117. R. Pietri, A. Lewis, R.G. Leon, G. Casabona, L. Kiger, S.R. Yeh, S. Fernandez-Alberti, M.C. Marden, C.L. Cadilla, and J. Lopez-Garriga Factors controlling the reactivity of hydrogen sulfide with hemeproteins Biochemistry 48 2009 4881 4894
118. B.C. Hill, T.C. Woon, P. Nicholls, J. Peterson, C. Greenwood, and A.J. Thomson Interactions of sulphide and other ligands with cytochrome c oxidase. An electron-paramagnetic-resonance study Biochem. J. 224 1984 591 600
119. 2S induces a suspended animation-like state in mice Science 308 2005 518 (Pubitemid 40570576)
120. L.C. Petersen The effect of inhibitors on the oxygen kinetics of cytochrome c oxidase Biochim. Biophys. Acta 460 1977 299 307
121. X. Leschelle, M. Goubern, M. Andriamihaja, H.M. Blottiere, E. Couplan, M.D. Gonzalez-Barroso, C. Petit, A. Pagniez, C. Chaumontet, B. Mignotte, F. Bouillaud, and F. Blachier Adaptative metabolic response of human colonic epithelial cells to the adverse effects of the luminal compound sulfide Biochim. Biophys. Acta 1725 2005 201 212 (Pubitemid 41253930)
122. R. Yong, and D.G. Searcy Sulfide oxidation coupled to ATP synthesis in chicken liver mitochondria Comp. Biochem. Physiol. B Biochem. Mol. Biol. 129 2001 129 137 (Pubitemid 32397712)
123. A.W. Nichol, I. Hendry, and D.B. Morell Mechanism of formation of sulphhaemoglobin Biochim. Biophys. Acta 156 1968 97 108
124. Y. Cheng, J.F. Ndisang, G. Tang, K. Cao, and R. Wang Hydrogen sulfide-induced relaxation of resistance mesenteric artery beds of rats Am. J. Physiol. Heart Circ. Physiol. 287 2004 H2316 H2323
125. 2S-induced vasorelaxation and underlying cellular and molecular mechanisms Am. J. Physiol. Heart Circ. Physiol. 283 2002 H474 H480
126. C.E. Cooper, and G.C. Brown The inhibition of mitochondrial cytochrome oxidase by the gases carbon monoxide, nitric oxide, hydrogen cyanide and hydrogen sulfide: chemical mechanism and physiological significance J. Bioenerg. Biomembr. 40 2008 533 539
127. G. Edwards, M. Feletou, and A.H. Weston Hydrogen sulfide as an endothelium-derived hyperpolarizing factor in rodent mesenteric arteries Circ. Res. 110 2012 e13 e14 (author reply e15-16)
128. Y. Nagai, M. Tsugane, J. Oka, and H. Kimura Hydrogen sulfide induces calcium waves in astrocytes FASEB J. 18 2004 557 559
129. A.E. Abele, and R.J. Miller Potassium channel activators abolish excitotoxicity in cultured hippocampal pyramidal neurons Neurosci. Lett. 115 1990 195 200 (Pubitemid 20231613)
130. Y. Kimura, Y. Goto, and H. Kimura Hydrogen sulfide increases glutathione production and suppresses oxidative stress in mitochondria Antioxid. Redox Signal. 12 2010 1 13
131. Z. Wang, D.X. Liu, F.W. Wang, Q. Zhang, Z.X. Du, J.M. Zhan, Q.H. Yuan, E.A. Ling, and A.J. Hao L-cysteine promotes the proliferation and differentiation of neural stem cells via the CBS/H(2)S pathway Neuroscience 237 2013 106 117
132. R. Wang Signaling pathways for the vascular effects of hydrogen sulfide Curr. Opin. Nephrol. Hypertens. 20 2011 107 112
133. C. Peers, C.C. Bauer, J.P. Boyle, J.L. Scragg, and M.L. Dallas Modulation of ion channels by hydrogen sulfide Antioxid. Redox Signal. 17 2012 95 105
134. Z. Zhang, H. Huang, P. Liu, C. Tang, and J. Wang Hydrogen sulfide contributes to cardioprotection during ischemia-reperfusion injury by opening K ATP channels Can. J. Physiol. Pharmacol. 85 2007 1248 1253 (Pubitemid 351196401)
135. 2S in rat insulin-secreting cells and the underlying mechanisms J. Physiol. 569 2005 519 531 (Pubitemid 41830119)
136. E. Distrutti, L. Sediari, A. Mencarelli, B. Renga, S. Orlandi, E. Antonelli, F. Roviezzo, A. Morelli, G. Cirino, J.L. Wallace, and S. Fiorucci Evidence that hydrogen sulfide exerts antinociceptive effects in the gastrointestinal tract by activating KATP channels J. Pharmacol. Exp. Ther. 316 2006 325 335 (Pubitemid 41832612)
137. A.R. Gade, M. Kang, and H.I. Akbarali Hydrogen sulfide as an allosteric modulator of ATP-sensitive potassium channels in colonic inflammation Mol. Pharmacol. 83 2013 294 306
138. B. Jiang, G. Tang, K. Cao, L. Wu, and R. Wang Molecular mechanism for H(2)S-induced activation of K(ATP) channels Antioxid. Redox Signal. 12 2010 1167 1178
139. K.R. Olson, M.J. Healy, Z. Qin, N. Skovgaard, B. Vulesevic, D.W. Duff, N.L. Whitfield, G. Yang, R. Wang, and S.F. Perry Hydrogen sulfide as an oxygen sensor in trout gill chemoreceptors Am. J. Physiol. Regul. Integr. Comp. Physiol. 295 2008 R669 R680
140. Q. Li, B. Sun, X. Wang, Z. Jin, Y. Zhou, L. Dong, L.H. Jiang, and W. Rong A crucial role for hydrogen sulfide in oxygen sensing via modulating large conductance calcium-activated potassium channels Antioxid. Redox Signal. 12 2010 1179 1189
141. V. Telezhkin, S.P. Brazier, S. Cayzac, C.T. Muller, D. Riccardi, and P.J. Kemp Hydrogen sulfide inhibits human BK(Ca) channels Adv. Exp. Med. Biol. 648 2009 65 72
142. V. Telezhkin, S.P. Brazier, S.H. Cayzac, W.J. Wilkinson, D. Riccardi, and P.J. Kemp Mechanism of inhibition by hydrogen sulfide of native and recombinant BKCa channels Respir. Physiol. Neurobiol. 172 2010 169 178
143. G.F. Sitdikova, T.M. Weiger, and A. Hermann Hydrogen sulfide increases calcium-activated potassium (BK) channel activity of rat pituitary tumor cells Pflugers Arch. 459 2010 389 397
144. A. Kawabata, T. Ishiki, K. Nagasawa, S. Yoshida, Y. Maeda, T. Takahashi, F. Sekiguchi, T. Wada, S. Ichida, and H. Nishikawa Hydrogen sulfide as a novel nociceptive messenger Pain 132 2007 74 81 (Pubitemid 47494563)
145. M.T. Nelson, S.M. Todorovic, and E. Perez-Reyes The role of T-type calcium channels in epilepsy and pain Curr. Pharm. Des. 12 2006 2189 2197 (Pubitemid 43891394)
146. L.A. Swayne, and E. Bourinet Voltage-gated calcium channels in chronic pain: emerging role of alternative splicing Pflugers Arch. 456 2008 459 466
147. Y.G. Sun, Y.X. Cao, W.W. Wang, S.F. Ma, T. Yao, and Y.C. Zhu Hydrogen sulphide is an inhibitor of L-type calcium channels and mechanical contraction in rat cardiomyocytes Cardiovasc. Res. 79 2008 632 641
148. 2 + channels Antioxid. Redox Signal. 10 2008 31 42
149. 2 + channels to extracellular oxidative/nitrosative stress in cerebellar granule cells J. Neurochem. 92 2005 973 989 (Pubitemid 40229569)
150. P.R. Strege, C.E. Bernard, R.E. Kraichely, A. Mazzone, L. Sha, A. Beyder, S.J. Gibbons, D.R. Linden, M.L. Kendrick, M.G. Sarr, J.H. Szurszewski, and G. Farrugia Hydrogen sulfide is a partially redox-independent activator of the human jejunum Na + channel, Nav1.5 Am. J. Physiol. Gastrointest. Liver Physiol. 300 2011 G1105 G1114
151. M. Trevisani, R. Patacchini, P. Nicoletti, R. Gatti, D. Gazzieri, N. Lissi, G. Zagli, C. Creminon, P. Geppetti, and S. Harrison Hydrogen sulfide causes vanilloid receptor 1-mediated neurogenic inflammation in the airways Br. J. Pharmacol. 145 2005 1123 1131 (Pubitemid 43079985)
152. T. Streng, H.E. Axelsson, P. Hedlund, D.A. Andersson, S.E. Jordt, S. Bevan, K.E. Andersson, E.D. Hogestatt, and P.M. Zygmunt Distribution and function of the hydrogen sulfide-sensitive TRPA1 ion channel in rat urinary bladder Eur. Urol. 53 2008 391 399
153. L. Malekova, O. Krizanova, and K. Ondrias H(2)S and HS(-) donor NaHS inhibits intracellular chloride channels Gen. Physiol. Biophys. 28 2009 190 194
154. G. Tang, L. Wu, and R. Wang Interaction of hydrogen sulfide with ion channels Clin. Exp. Pharmacol. Physiol. 37 2010 753 763
155. J.G. Dickhout, R.E. Carlisle, D.E. Jerome, Z. Mohammed-Ali, H. Jiang, G. Yang, S. Mani, S.K. Garg, R. Banerjee, R.J. Kaufman, K.N. Maclean, R. Wang, and R.C. Austin Integrated stress response modulates cellular redox state via induction of cystathionine gamma-lyase: cross-talk between integrated stress response and thiol metabolism J. Biol. Chem. 287 2012 7603 7614
156. N.R. Prabhakar NO and CO as second messengers in oxygen sensing in the carotid body Respir. Physiol. 115 1999 161 168 (Pubitemid 29206481)
157. K.R. Olson, R.A. Dombkowski, M.J. Russell, M.M. Doellman, S.K. Head, N.L. Whitfield, and J.A. Madden Hydrogen sulfide as an oxygen sensor/transducer in vertebrate hypoxic vasoconstriction and hypoxic vasodilation J. Exp. Biol. 209 2006 4011 4023 (Pubitemid 44769370)
158. N. Skovgaard, and K.R. Olson Hydrogen sulfide mediates hypoxic vasoconstriction through a production of mitochondrial ROS in trout gills Am. J. Physiol. Regul. Integr. Comp. Physiol. 303 2012 R487 R494
159. 2 sensing in the carotid body Proc. Natl. Acad. Sci. U. S. A. 107 2010 10719 10724
160. R.C. Zanardo, V. Brancaleone, E. Distrutti, S. Fiorucci, G. Cirino, and J.L. Wallace Hydrogen sulfide is an endogenous modulator of leukocyte-mediated inflammation FASEB J. 20 2006 2118 2120
161. E. Ekundi-Valentim, K.T. Santos, E.A. Camargo, A. Denadai-Souza, S.A. Teixeira, C.I. Zanoni, A.D. Grant, J. Wallace, M.N. Muscara, and S.K. Costa Differing effects of exogenous and endogenous hydrogen sulphide in carrageenan-induced knee joint synovitis in the rat Br. J. Pharmacol. 159 2010 1463 1474
162. M. Whiteman, L. Li, P. Rose, C.H. Tan, D.B. Parkinson, and P.K. Moore The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages Antioxid. Redox Signal. 12 2010 1147 1154
163. L. Li, M. Salto-Tellez, C.H. Tan, M. Whiteman, and P.K. Moore GYY4137, a novel hydrogen sulfide-releasing molecule, protects against endotoxic shock in the rat Free Radic. Biol. Med. 47 2009 103 113
164. S. Fiorucci, E. Antonelli, E. Distrutti, G. Rizzo, A. Mencarelli, S. Orlandi, R. Zanardo, B. Renga, M. Di Sante, A. Morelli, G. Cirino, and J.L. Wallace Inhibition of hydrogen sulfide generation contributes to gastric injury caused by anti-inflammatory nonsteroidal drugs Gastroenterology 129 2005 1210 1224 (Pubitemid 41446861)
165. T. Li, B. Zhao, C. Wang, H. Wang, Z. Liu, W. Li, H. Jin, C. Tang, and J. Du Regulatory effects of hydrogen sulfide on IL-6, IL-8 and IL-10 levels in the plasma and pulmonary tissue of rats with acute lung injury Exp. Biol. Med. (Maywood) 233 2008 1081 1087
166. X.H. Wang, F. Wang, S.J. You, Y.J. Cao, L.D. Cao, Q. Han, C.F. Liu, and L.F. Hu Dysregulation of cystathionine gamma-lyase (CSE)/hydrogen sulfide pathway contributes to ox-LDL-induced inflammation in macrophage Cell. Signal. 25 2013 2255 2262
167. S.K. Jain, D. Micinski, B.J. Lieblong, and T. Stapleton Relationship between hydrogen sulfide levels and HDL-cholesterol, adiponectin, and potassium levels in the blood of healthy subjects Atherosclerosis 225 2012 242 245
168. J.L. Wallace, L. Vong, W. McKnight, M. Dicay, and G.R. Martin Endogenous and exogenous hydrogen sulfide promotes resolution of colitis in rats Gastroenterology 137 2009 569 578 (578 e561)
169. A.L. Groeger, C. Cipollina, M.P. Cole, S.R. Woodcock, G. Bonacci, T.K. Rudolph, V. Rudolph, B.A. Freeman, and F.J. Schopfer Cyclooxygenase-2 generates anti-inflammatory mediators from omega-3 fatty acids Nat. Chem. Biol. 6 2010 433 441
170. H. Jing, E. Vassiliou, and D. Ganea Prostaglandin E2 inhibits production of the inflammatory chemokines CCL3 and CCL4 in dendritic cells J. Leukoc. Biol. 74 2003 868 879 (Pubitemid 38040363)
171. E. Vassiliou, H. Jing, and D. Ganea Prostaglandin E2 inhibits TNF production in murine bone marrow-derived dendritic cells Cell. Immunol. 223 2003 120 132 (Pubitemid 37188379)
172. M.A. Mariggio, V. Minunno, S. Riccardi, R. Santacroce, P. De Rinaldis, and R. Fumarulo Sulfide enhancement of PMN apoptosis Immunopharmacol. Immunotoxicol. 20 1998 399 408 (Pubitemid 28432237)
173. L. Zhi, A.D. Ang, H. Zhang, P.K. Moore, and M. Bhatia Hydrogen sulfide induces the synthesis of proinflammatory cytokines in human monocyte cell line U937 via the ERK-NF-kappaB pathway J. Leukoc. Biol. 81 2007 1322 1332 (Pubitemid 46702052)
174. H. Zhang, L. Zhi, S.M. Moochhala, P.K. Moore, and M. Bhatia Endogenous hydrogen sulfide regulates leukocyte trafficking in cecal ligation and puncture-induced sepsis J. Leukoc. Biol. 82 2007 894 905 (Pubitemid 47511050)
175. D. Dal-Secco, T.M. Cunha, A. Freitas, J.C. Alves-Filho, F.O. Souto, S.Y. Fukada, R. Grespan, N.M. Alencar, A.F. Neto, M.A. Rossi, S.H. Ferreira, J.S. Hothersall, and F.Q. Cunha Hydrogen sulfide augments neutrophil migration through enhancement of adhesion molecule expression and prevention of CXCR2 internalization: role of ATP-sensitive potassium channels J. Immunol. 181 2008 4287 4298
176. L. Li, M. Bhatia, Y.Z. Zhu, Y.C. Zhu, R.D. Ramnath, Z.J. Wang, F.B. Anuar, M. Whiteman, M. Salto-Tellez, and P.K. Moore Hydrogen sulfide is a novel mediator of lipopolysaccharide-induced inflammation in the mouse FASEB J. 19 2005 1196 1198 (Pubitemid 40946463)
177. Y. Hui, J. Du, C. Tang, G. Bin, and H. Jiang Changes in arterial hydrogen sulfide (H(2)S) content during septic shock and endotoxin shock in rats J. Infect. 47 2003 155 160 (Pubitemid 36896399)
178. M. Collin, F.B. Anuar, O. Murch, M. Bhatia, P.K. Moore, and C. Thiemermann Inhibition of endogenous hydrogen sulfide formation reduces the organ injury caused by endotoxemia Br. J. Pharmacol. 146 2005 498 505 (Pubitemid 41487065)
179. M. Bhatia, J. Sidhapuriwala, S.M. Moochhala, and P.K. Moore Hydrogen sulphide is a mediator of carrageenan-induced hindpaw oedema in the rat Br. J. Pharmacol. 145 2005 141 144 (Pubitemid 40756518)
180. Y.Y. Mok, M.S. Atan, C. Yoke Ping, W. Zhong Jing, M. Bhatia, S. Moochhala, and P.K. Moore Role of hydrogen sulphide in haemorrhagic shock in the rat: protective effect of inhibitors of hydrogen sulphide biosynthesis Br. J. Pharmacol. 143 2004 881 889 (Pubitemid 39664847)
181. T. Goslar, T. Mars, and M. Podbregar Total plasma sulfide as a marker of shock severity in nonsurgical adult patients Shock 36 2011 350 355
182. Ouml, S. Lkel, and M. Grieshaber Sulphide oxidation and oxidative phosphorylation in the mitochondria of the lugworm J. Exp. Biol. 200 1997 83 92 (Pubitemid 27058898)
183. M. Goubern, M. Andriamihaja, T. Nubel, F. Blachier, and F. Bouillaud Sulfide, the first inorganic substrate for human cells FASEB J. 21 2007 1699 1706 (Pubitemid 46855615)
184. F. Bouillaud, and F. Blachier Mitochondria and sulfide: a very old story of poisoning, feeding, and signaling? Antioxid. Redox Signal. 15 2011 379 391
185. K. Modis, C. Coletta, K. Erdelyi, A. Papapetropoulos, and C. Szabo Intramitochondrial hydrogen sulfide production by 3-mercaptopyruvate sulfurtransferase maintains mitochondrial electron flow and supports cellular bioenergetics FASEB J. 27 2013 601 611
186. J.W. Elrod, J.W. Calvert, J. Morrison, J.E. Doeller, D.W. Kraus, L. Tao, X. Jiao, R. Scalia, L. Kiss, C. Szabo, H. Kimura, C.W. Chow, and D.J. Lefer Hydrogen sulfide attenuates myocardial ischemia-reperfusion injury by preservation of mitochondrial function Proc. Natl. Acad. Sci. U. S. A. 104 2007 15560 15565 (Pubitemid 47502956)
187. 2S on human aorta smooth muscle cells FASEB J. 20 2006 553 555 (Pubitemid 46671247)
188. G. Yang, L. Wu, S. Bryan, N. Khaper, S. Mani, and R. Wang Cystathionine gamma-lyase deficiency and overproliferation of smooth muscle cells Cardiovasc. Res. 86 2010 487 495
189. G. Yang, W. Yang, L. Wu, and R. Wang H2S, endoplasmic reticulum stress, and apoptosis of insulin-secreting beta cells J. Biol. Chem. 282 2007 16567 16576 (Pubitemid 47100397)
190. C.X. Tiong, M. Lu, and J.S. Bian Protective effect of hydrogen sulphide against 6-OHDA-induced cell injury in SH-SY5Y cells involves PKC/PI3K/Akt pathway Br. J. Pharmacol. 161 2010 467 480
191. W.L. Yin, J.Q. He, B. Hu, Z.S. Jiang, and X.Q. Tang Hydrogen sulfide inhibits MPP(+)-induced apoptosis in PC12 cells Life Sci. 85 2009 269 275
192. H. Kimura Hydrogen sulfide: from brain to gut Antioxid. Redox Signal. 12 2010 1111 1123
193. B. Teague, S. Asiedu, and P.K. Moore The smooth muscle relaxant effect of hydrogen sulphide in vitro: evidence for a physiological role to control intestinal contractility Br. J. Pharmacol. 137 2002 139 145
194. B. Hennig, and M. Diener Actions of hydrogen sulphide on ion transport across rat distal colon Br. J. Pharmacol. 158 2009 1263 1275
195. E. Pouokam, and M. Diener Mechanisms of actions of hydrogen sulphide on rat distal colonic epithelium Br. J. Pharmacol. 162 2011 392 404
196. R. Schicho, D. Krueger, F. Zeller, C.W. Von Weyhern, T. Frieling, H. Kimura, I. Ishii, R. De Giorgio, B. Campi, and M. Schemann Hydrogen sulfide is a novel prosecretory neuromodulator in the guinea-pig and human colon Gastroenterology 131 2006 1542 1552 (Pubitemid 44708939)
197. F. Ise, H. Takasuka, S. Hayashi, K. Takahashi, M. Koyama, E. Aihara, and K. Takeuchi Stimulation of duodenal HCO(3)(-) secretion by hydrogen sulphide in rats: relation to prostaglandins, nitric oxide and sensory neurones Acta Physiol. (Oxf.) 201 2011 117 126
198. M. Matsunami, S. Kirishi, T. Okui, and A. Kawabata Hydrogen sulfide-induced colonic mucosal cytoprotection involves T-type calcium channel-dependent neuronal excitation in rats J. Physiol. Pharmacol. 63 2012 61 68
199. M.D. Levitt, J. Springfield, J. Furne, T. Koenig, and F.L. Suarez Physiology of sulfide in the rat colon: use of bismuth to assess colonic sulfide production J. Appl. Physiol. 92 2002 1655 1660 (Pubitemid 34670923)
200. E.A. Magee, C.J. Richardson, R. Hughes, and J.H. Cummings Contribution of dietary protein to sulfide production in the large intestine: an in vitro and a controlled feeding study in humans Am. J. Clin. Nutr. 72 2000 1488 1494
201. M.D. Levitt, J. Furne, J. Springfield, F. Suarez, and E. DeMaster Detoxification of hydrogen sulfide and methanethiol in the cecal mucosa J. Clin. Invest. 104 1999 1107 1114 (Pubitemid 29536321)
202. J. Furne, J. Springfield, T. Koenig, E. DeMaster, and M.D. Levitt Oxidation of hydrogen sulfide and methanethiol to thiosulfate by rat tissues: a specialized function of the colonic mucosa Biochem. Pharmacol. 62 2001 255 259 (Pubitemid 32522947)
203. R.A. Weisiger, L.M. Pinkus, and W.B. Jakoby Thiol S-methyltransferase: suggested role in detoxication of intestinal hydrogen sulfide Biochem. Pharmacol. 29 1980 2885 2887 (Pubitemid 10021171)
204. R. Picton, M.C. Eggo, G.A. Merrill, M.J. Langman, and S. Singh Mucosal protection against sulphide: importance of the enzyme rhodanese Gut 50 2002 201 205 (Pubitemid 34087932)
205. F. Blachier, A.M. Davila, S. Mimoun, P.H. Benetti, C. Atanasiu, M. Andriamihaja, R. Benamouzig, F. Bouillaud, and D. Tome Luminal sulfide and large intestine mucosa: friend or foe? Amino Acids 39 2010 335 347
206. W.E. Roediger, A. Duncan, O. Kapaniris, and S. Millard Reducing sulfur compounds of the colon impair colonocyte nutrition: implications for ulcerative colitis Gastroenterology 104 1993 802 809 (Pubitemid 23059579)
207. W.E. Roediger Role of anaerobic bacteria in the metabolic welfare of the colonic mucosa in man Gut 21 1980 793 798 (Pubitemid 11209227)
208. J. Levine, C.J. Ellis, J.K. Furne, J. Springfield, and M.D. Levitt Fecal hydrogen sulfide production in ulcerative colitis Am. J. Gastroenterol. 93 1998 83 87 (Pubitemid 29065520)
209. M.C. Pitcher, E.R. Beatty, and J.H. Cummings The contribution of sulphate reducing bacteria and 5-aminosalicylic acid to faecal sulphide in patients with ulcerative colitis Gut 46 2000 64 72 (Pubitemid 30307679)
210. K.L. Flannigan, J.G. Ferraz, R. Wang, and J.L. Wallace Enhanced synthesis and diminished degradation of hydrogen sulfide in experimental colitis: a site-specific, pro-resolution mechanism PLoS One 8 2013 e71962
211. E. Taniguchi, M. Matsunami, T. Kimura, D. Yonezawa, T. Ishiki, F. Sekiguchi, H. Nishikawa, Y. Maeda, H. Ishikura, and A. Kawabata Rhodanese, but not cystathionine-gamma-lyase, is associated with dextran sulfate sodium-evoked colitis in mice: a sign of impaired colonic sulfide detoxification? Toxicology 264 2009 96 103
212. W.E. Roediger, W. Babidge, and S. Millard Methionine derivatives diminish sulphide damage to colonocytes-implications for ulcerative colitis Gut 39 1996 77 81 (Pubitemid 26239110)
213. J. Moore, W. Babidge, S. Millard, and W. Roediger Colonic luminal hydrogen sulfide is not elevated in ulcerative colitis Dig. Dis. Sci. 43 1998 162 165 (Pubitemid 28081657)
214. J.K. Furne, F.L. Suarez, S.L. Ewing, J. Springfield, and M.D. Levitt Binding of hydrogen sulfide by bismuth does not prevent dextran sulfate-induced colitis in rats Dig. Dis. Sci. 45 2000 1439 1443 (Pubitemid 30636522)
215. J.L. Wallace, M. Dicay, W. McKnight, and G.R. Martin Hydrogen sulfide enhances ulcer healing in rats FASEB J. 21 2007 4070 4076 (Pubitemid 350232363)
216. I. Hirata, Y. Naito, T. Takagi, K. Mizushima, T. Suzuki, T. Omatsu, O. Handa, H. Ichikawa, H. Ueda, and T. Yoshikawa Endogenous hydrogen sulfide is an anti-inflammatory molecule in dextran sodium sulfate-induced colitis in mice Dig. Dis. Sci. 56 2011 1379 1386