Specialized postsynaptic morphology enhances neurotransmitter dilution and high-frequency signaling at an auditory synapse

Journal of Neuroscience

Volumn 34, Issue 24, 2014, Pages 8358-8372

  Graydon, Cole W ^a,b   Cho, Soyoun ^c   Diamond, Jeffrey S ^a   Kachar, Bechara ^b   von Gersdorff, Henrique ^c   Grimes, William N ^a,d  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^b NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS   (United States)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^d UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Auditory; Diffusion; Glutamate; Hair cell; Ribbon synapse; Synapse

Indexed keywords

CYCLOTHIAZIDE; GLUTAMATE TRANSPORTER; NEUROTRANSMITTER;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANURA; ARTICLE; AUDITORY NERVOUS SYSTEM; BRAIN ELECTROPHYSIOLOGY; CELL STRUCTURE; COMPUTER MODEL; CONNECTOME; CONTROLLED STUDY; DESENSITIZATION; DIFFUSION; DILUTION; ELECTRON MICROSCOPY; EVOKED RESPONSE; EXTRACELLULAR SPACE; FEMALE; HAIR CELL; MALE; MONTE CARLO METHOD; NONHUMAN; POSTSYNAPTIC POTENTIA; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION; SENSITIVITY ANALYSIS; SENSORY NERVE; SIGNAL TRANSDUCTION; SIMULATION; SYNAPSE; SYNAPTIC TRANSMISSION; WHOLE CELL PATCH CLAMP;

AUDITORY; DIFFUSION; GLUTAMATE; HAIR CELL; RIBBON SYNAPSE; SYNAPSE;

ALGORITHMS; ANIMALS; ASPARTIC ACID; BENZOTHIADIAZINES; CALCIUM; COMPUTER SIMULATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC STIMULATION; EXCITATORY POSTSYNAPTIC POTENTIALS; FEMALE; GLUTAMIC ACID; HAIR CELLS, AUDITORY; MALE; MICROSCOPY, ELECTRON; MODELS, NEUROLOGICAL; NEUROTRANSMITTER AGENTS; PATCH-CLAMP TECHNIQUES; RANA CATESBEIANA; SIGNAL TRANSDUCTION; SYNAPTIC TRANSMISSION;

EID: 84902212099     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4493-13.2014     Document Type: Article

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