Size-based molecular diagnostics using plasma DNA for noninvasive prenatal testing

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 23, 2014, Pages 8583-8588

  Yu, Stephanie C Y ^a,b   Chan, K C Allen ^a,b   Zheng, Yama W L ^a,b,e   Jiang, Peiyong ^a,b   Liao, Gary J W ^a,b   Sun, Hao ^a,b   Akolekar, Ranjit ^c,f   Leung, Tak Y ^b   Go, Attie T J I ^d,g   Van Vugt, John M G ^d,h   Minekawa, Ryoko ^c   Oudejans, Cees B M ^d   Nicolaides, Kypros H ^c   Chiu, Rossa W K ^a,b   Lo, Y M Dennis ^a,b  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^c KING S COLLEGE HOSPITAL   (United Kingdom)

^d VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^e MEDICAL COLLEGE OF GEORGIA   (United States)

^f MEDWAY MARITIME HOSPITAL   (United Kingdom)

^g ERASMUS MEDICAL CENTER   (Netherlands)

^h RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Down syndrome; Fetal aneuploidy; Next generation sequencing; Size profiling; Turner syndrome

Indexed keywords

DNA FRAGMENT;

ANEUPLOIDY; ARTICLE; CAPILLARY ELECTROPHORESIS; CHROMOSOME ABERRATION; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; DNA DETERMINATION; FEMALE; FETUS; GENE SEQUENCE; HUMAN; MALE; MATERNAL PLASMA; MOLECULAR DIAGNOSIS; MOLECULAR SIZE; MONOSOMY X; NON INVASIVE PROCEDURE; PRENATAL DIAGNOSIS; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; TRISOMY 18; TRISOMY 21;

DOWN SYNDROME; FETAL ANEUPLOIDY; NEXT-GENERATION SEQUENCING; SIZE PROFILING; TURNER SYNDROME;

CHROMOSOME DISORDERS; CHROMOSOMES, HUMAN, PAIR 13; CHROMOSOMES, HUMAN, PAIR 18; CHROMOSOMES, HUMAN, X; DNA; DOWN SYNDROME; ELECTROPHORESIS, CAPILLARY; FEMALE; FETAL DISEASES; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; MONOSOMY; PATHOLOGY, MOLECULAR; PREGNANCY; PRENATAL DIAGNOSIS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TRISOMY;

EID: 84902193969     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1406103111     Document Type: Article

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