Inhibition of Delta-like 4 mediated signaling induces abortion in mice due to deregulation of decidual angiogenesis

Placenta

Volumn 35, Issue 7, 2014, Pages 501-508

  Garcia Pascual C M ^a   Ferrero, H ^a   Zimmermann, R C ^b   Simon C ^a   Pellicer, A ^a   Gomez R ^a  

^a Instituto Universitario IVI INCLIVA   (Spain)

^b Department of Obstetrics and Gynecology Columbia University ^*  (United States)

Author keywords

Angiogenesis; Decidua; Dll4; Keywords; Notch pathway; Pregnancy disruption; VEGF

Indexed keywords

ANTIBODY; DELTA LIKE 4 BLOCKING ANTIBODY; IMMUNOGLOBULIN G; NOTCH RECEPTOR; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2; BLOCKING ANTIBODY; DLL4 PROTEIN, MOUSE; MEMBRANE PROTEIN; SIGNAL PEPTIDE; VEGFR2 PROTEIN, MOUSE;

ABORTION; ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DECIDUA; EMBRYO DEVELOPMENT; EMBRYO GROWTH; ENDOTHELIUM CELL; FEMALE; INTRAUTERINE GROWTH RETARDATION; MOUSE; NONHUMAN; OVARIECTOMY; PHENOTYPE; PREGNANCY; PRIORITY JOURNAL; PROGESTERONE BLOOD LEVEL; UTERUS; UTERUS WEIGHT; VASCULARIZATION; ANIMAL; ANTAGONISTS AND INHIBITORS; DISEASE MODEL; EMBRYO DEATH; ETIOLOGY; GESTATIONAL AGE; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; ANTIBODIES, BLOCKING; APOPTOSIS; CELL PROLIFERATION; DECIDUA; DISEASE MODELS, ANIMAL; EMBRYO LOSS; EMBRYONIC DEVELOPMENT; FEMALE; GESTATIONAL AGE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MICE; NEOVASCULARIZATION, PHYSIOLOGIC; PREGNANCY; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

EID: 84902178328     PISSN: 01434004     EISSN: 15323102     Source Type: Journal    
DOI: 10.1016/j.placenta.2014.03.019     Document Type: Article

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