Early intra-articular complement activation in ankle fractures

BioMed Research International

Volumn 2014, Issue , 2014, Pages

  Schmal, Hagen ^a   Salzmann, Gian M ^a   Niemeyer, Philipp ^a   Langenmair, Elia ^a   Guo, Renfeng ^b   Schneider, Conny ^b   Habel, Maria ^b   Riedemann, Niels ^b  

^a UNIVERSITY OF FREIBURG   (Germany)

^b Inflarx   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AGGRECAN; BASIC FIBROBLAST GROWTH FACTOR RECEPTOR; C REACTIVE PROTEIN; COMPLEMENT COMPONENT C3A; COMPLEMENT COMPONENT C5A; COMPLEMENT MEMBRANE ATTACK COMPLEX; INTERLEUKIN 1BETA; SOMATOMEDIN C; COMPLEMENT; FIBROBLAST GROWTH FACTOR 2; IGF1 PROTEIN, HUMAN; IL1B PROTEIN, HUMAN;

ADULT; ANKLE FRACTURE; ARTICLE; CASE STUDY; CELL COMPOSITION; CELL INFILTRATION; CLINICAL ARTICLE; COMPLEMENT ACTIVATION; CORRELATION ANALYSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; ERYTHROCYTE; FEMALE; FRACTURE EXTERNAL FIXATION; HUMAN; INFLAMMATORY CELL; INTRAARTICULAR FRACTURE; JOINT EFFUSION; MALE; MONOCYTE; NEUTROPHIL; OSTEOCHONDRITIS DISSECANS; PROSPECTIVE STUDY; PROTEIN EXPRESSION; ANKLE; ANKLE FRACTURES; CLINICAL TRIAL; GENE EXPRESSION REGULATION; METABOLISM; MIDDLE AGED; PATHOLOGY; TIME;

ADULT; ANKLE FRACTURES; ANKLE JOINT; COMPLEMENT ACTIVATION; COMPLEMENT SYSTEM PROTEINS; FIBROBLAST GROWTH FACTOR 2; GENE EXPRESSION REGULATION; HUMANS; INSULIN-LIKE GROWTH FACTOR I; INTERLEUKIN-1BETA; MALE; MIDDLE AGED; OSTEOCHONDRITIS DISSECANS; TIME FACTORS;

EID: 84902157021     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2014/426893     Document Type: Article

References (34)

1. Lubbeke A., Salvo D., Stern R., Hoffmeyer P., Holzer N., Assal M., Risk factors for post-traumatic osteoarthritis of the ankle: an eighteen year follow-up study. International Orthopaedics 2012 36 7 1403 1410 10.1007/s00264-011-1472-7
2. Kramer W. C., Hendricks K. J., Wang J., Pathogenetic mechanisms of posttraumatic osteoarthritis: opportunities for early intervention. International Journal of Clinical and Experimental Medicine 2011 4 4 285 298 2-s2.0-82955193813
3. Patra D., Sandell L. J., Recent advances in biomarkers in osteoarthritis. Current Opinion in Rheumatology 2011 23 5 465 470 2-s2.0-80052026269 10.1097/BOR.0b013e328349a32b
4. Bigoni M., Sacerdote P., Turati M., Franchi S., Gandolla M., Gaddi D., Moretti S., Munegato D., Augusti C. A., Bresciani E., Omeljaniuk R. J., Locatelli V., Torsello A., Acute and late changes in intraarticular cytokine levels following anterior cruciate ligament injury. Journal of Orthopaedic Research 2013 31 2 315 321 10.1002/jor.22208
5. Kraus V. B., Birmingham J., Stabler T. V., Feng S., Taylor D. C., Moorman C. T., Garrett W. E., Toth A. P., Effects of intraarticular IL1-Ra for acute anterior cruciate ligament knee injury: a randomized controlled pilot trial (NCT00332254). Osteoarthritis and Cartilage 2012 20 4 271 278 2-s2.0-84858619829 10.1016/j.joca.2011.12.009
6. Czermak B. J., Sarma V., Pierson C. L., Warner R. L., Huber-Lang M., Bless N. M., Schmal H., Friedl H. P., Ward P. A., Protective effects of C5a blockade in sepsis. Nature Medicine 1999 5 7 788 792 2-s2.0-0033052453 10.1038/10512 (Pubitemid 29318613)
7. Wang L., Han G., Wang R., Chen G., Xu R., Xiao H., Li X., Geng S., Li Y., Li X., Wang J., Feng J., Riedemann N. C., Guo R., Shen B., Li Y., Regulation of IL-8 production by complement-activated product, C5a, in vitro and in vivo during sepsis. Clinical Immunology 2010 137 1 157 165 2-s2.0-77956620297 10.1016/j.clim.2010.05.012
8. Ehrnthaller C., Huber-Lang M., Nilsson P., Bindl R., Redeker S., Recknagel S., Rapp A., Mollnes T., Amling M., Gebhard F., Ignatius A., Complement c3 and c5 deficiency affects fracture healing. PLoS ONE 2013 8 11 e81341 10.1371/journal.pone.0081341
9. Hengartner N. E., Fiedler J., Ignatius A., Brenner R. E., IL-1beta inhibits human osteoblast migration. Molecular Medicine 2013 19 36 42
10. Ignatius A., Ehrnthaller C., Brenner R. E., Kreja L., Schoengraf P., Lisson P., Blakytny R., Recknagel S., Claes L., Gebhard F., Lambris J. D., Huber-Lang M., The anaphylatoxin receptor C5aR is present during fracture healing in rats and mediates osteoblast migration in vitro. Journal of Trauma: Injury, Infection and Critical Care 2011 71 4 952 960 2-s2.0-80054024294 10.1097/TA.0b013e3181f8aa2d
11. Ignatius A., Schoengraf P., Kreja L., Liedert A., Recknagel S., Kandert S., Brenner R. E., Schneider M., Lambris J. D., Huber-Lang M., Complement C3a and C5a modulate osteoclast formation and inflammatory response of osteoblasts in synergism with IL-1 β Journal of Cellular Biochemistry 2011 112 9 2594 2605 2-s2.0-84860389426 10.1002/jcb.23186
12. Schmal H., Henkelmann R., Mehlhorn A. T., Reising K., Bode G., Sudkamp N. P., Niemeyer P., Synovial cytokine expression in ankle osteoarthritis depends on age and stage. Knee Surgery Sports Traumatology Arthroscopy 2013 10.1007/s00167-013-2719-1
13. Zwingmann J., Sudkamp N. P., Schmal H., Niemeyer P., Surgical treatment of osteochondritis dissecans of the talus: a systematic review. Archives of Orthopaedic and Trauma Surgery 2012 132 9 1241 1250 10.1007/s00402-012-1544-1
14. Keats A. S., The ASA classification of physical status-a recapitulation. Anesthesiology 1978 49 4 233 236 2-s2.0-0018025871
15. Tscherne H., Oestern H. J., A new classification of soft-tissue damage in open and closed fractures. Traumatology 1982 85 3 111 115 2-s2.0-0020038192 (Pubitemid 12133393)
16. Huang K., Wu L. D., Suppression of aggrecanase: a novel protective mechanism of dehydroepiandrosterone in osteoarthritis→ Molecular Biology Reports 2010 37 3 1241 1245 2-s2.0-77951903637 10.1007/s11033-009-9495-5
17. Lohmander L. S., Hoerrner L. A., Lark M. W., Metalloproteinases, tissue inhibitor, and proteoglycan fragments in knee synovial fluid in human osteoarthritis. Arthritis and Rheumatism 1993 36 2 181 189 2-s2.0-0027450277 (Pubitemid 23059328)
18. Schmal H., Mehlhorn A., Stoffel F., Kstler W., Sdkamp N. P., Niemeyer P., In vivo quantification of intraarticular cytokines in knees during natural and surgically induced cartilage repair. Cytotherapy 2009 11 8 1065 1075 2-s2.0-71149104044 10.3109/14653240903219130
19. Jang K. W., Buckwalter J. A., Martin J. A., Inhibition of cell-matrix adhesions prevents cartilage chondrocyte death following impact injury. Journal of Orthopaedic Research 2013 32 3 448 454 10.1002/jor.22523
20. Claes L., Recknagel S., Ignatius A., Fracture healing under healthy and inflammatory conditions. Nature Reviews Rheumatology 2012 8 3 133 143 2-s2.0-84857920401 10.1038/nrrheum.2012.1
21. Guo R. F., Ward P. A., Role of C5a in inflammatory responses. Annual Review of Immunology 2005 23 821 852 2-s2.0-17644388462 10.1146/annurev.immunol. 23.021704.115835 (Pubitemid 40563186)
22. Schmal H., Niemeyer P., Roesslein M., Hartl D., Loop T., Südkamp N. P., Stark G. B., Mehlhorn A. T., Comparison of cellular functionality of human mesenchymal stromal cells and PBMC. Cytotherapy 2007 9 1 69 79 2-s2.0-34247176765 10.1080/14653240601011557
23. Song K., Rao N. J., Chen M. L., Huang Z. J., Cao Y. G., Enhanced bone regeneration with sequential delivery of basic fibroblast growth factor and sonic hedgehog. Injury 2011 42 8 796 802 2-s2.0-79960004951 10.1016/j.injury. 2011.02.003
24. Schulze-Tanzil G., Kohl B., El Sayed K., Arens S., Ertel W., Stolzel K., John T., Anaphylatoxin receptors and complement regulatory proteins in human articular and non-articular chondrocytes: interrelation with cytokines. Cell and Tissue Research 2012 350 3 465 475 10.1007/s00441-012-1497-2
25. Korb L. C., Ahearn J. M., C1q binds directly and specifically to surface blebs of apoptotic human keratinocytes: complement deficiency and systemic lupus erythematosus revisited. The Journal of Immunology 1997 158 10 4525 4528 (Pubitemid 127483768)
26. Ogden C. A., DeCathelineau A., Hoffmann P. R., Bratton D., Fadok B., Ghebrehiwet V. A., Henson P. M., C1q and mannose binding lectin engagement of cell surface calreticulin and CD91 initiates macropinocytosis and uptake of apoptotic cells. Journal of Experimental Medicine 2001 194 6 781 795 2-s2.0-0035903289 10.1084/jem.194.6.781 (Pubitemid 32983014)
27. Nagasawa S., Activation of the alternative pathway of complement by apoptotic Jurkat cells. FEBS Letters 1994 351 3 419 422 2-s2.0-0028086284 10.1016/0014-5793(94)00897-3 (Pubitemid 24285348)
28. Happonen K. E., Heinegard D., Saxne T., Blom A. M., Interactions of the complement system with molecules of extracellular matrix: relevance for joint diseases. Immunobiology 2012 217 11 1088 1096 10.1016/j.imbio.2012.07.013
29. Riedemann N. C., Guo R. F., Gao H., Sun L., Hoesel M., Hollmann T. J., Wetsel R. A., Zetoune F. S., Ward P. A., Regulatory role of C5a on macrophage migration inhibitory factor release from neutrophils. Journal of Immunology 2004 173 2 1355 1359 2-s2.0-3142703604 (Pubitemid 38924315)
30. Wu A. C., Morrison N. A., Kelly W. L., Forwood M. R., MCP-1 expression is specifically regulated during activation of skeletal repair and remodeling. Calcified Tissue International 2013 92 6 566 575 10.1007/s00223-013-9718-6
31. Vincent T., Hermansson M., Bolton M., Wait R., Saklatvala J., Basic FGF mediates an immediate response of articular cartilage to mechanical injury. Proceedings of the National Academy of Sciences of the United States of America 2002 99 12 8259 8264 2-s2.0-0037062469 10.1073/pnas.122033199 (Pubitemid 34651040)
32. Schmal H., Zwingmann J., Fehrenbach M., Finkenzeller G., Stark G. B., Südkamp N. P., Hartl D., Mehlhorn A. T., bFGF influences human articular chondrocyte differentiation. Cytotherapy 2007 9 2 184 193 2-s2.0-34047168020 10.1080/14653240601182846 (Pubitemid 46510983)
33. Loeser R. F., Chubinskaya S., Pacione C., Im H. J., Basic fibroblast growth factor inhibits the anabolic activity of insulin-like growth factor 1 and osteogenic protein 1 in adult human articular chondrocytes. Arthritis and Rheumatism 2005 52 12 3910 3917 2-s2.0-29144507688 10.1002/art.21472 (Pubitemid 41798230)
34. Loeser R. F., Pacione C. A., Chubinskaya S., The combination of insulin-like growth factor 1 and osteogenic protein 1 promotes increased survival of and matrix synthesis by normal and osteoarthritic human articular chondrocytes. Arthritis and Rheumatism 2003 48 8 2188 2196 2-s2.0-0041571728 10.1002/art.11209 (Pubitemid 36959199)