Autoimmune diseases in HIV-infected patients: 52 cases and literature review

Autoimmunity Reviews

Volumn 13, Issue 8, 2014, Pages 850-857

  Iordache, Laura ^a   Launay, Odile ^b   Bouchaud, Olivier ^c   Jeantils, Vincent ^a   Goujard, Cécile ^d   Boue, Francois ^e   Cacoub, Patrice ^f,i,j,k   Hanslik, Thomas ^g   Mahr, Alfred ^h   Lambotte, Olivier ^d   Fain, Olivier ^a  

^a HÔPITAL JEAN VERDIER   (France)

^b Clinical Investigation Centre Cochin Hospital ^*  (France)

^c AVICENNE HOSPITAL   (France)

^d BICÊTRE HOSPITAL   (France)

^e HÔPITAL ANTOINE BÉCLÈRE   (France)

^f PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^g HÔPITAL AMBROISE PARÉ   (France)

^h SAINT LOUIS HOSPITAL   (France)

ⁱ SORBONNE UNIVERSITÉ   (France)

^j Unit of Dermatology   (France)

^k CNRS   (France)

more..

Author keywords

Autoimmunity; HIV; Immunosuppressant drugs

Indexed keywords

IMMUNOSUPPRESSIVE AGENT;

ANTIPHOSPHOLIPID SYNDROME; AUTOIMMUNE DISEASE; AUTOIMMUNE HEMOLYTIC ANEMIA; AUTOIMMUNE HEPATITIS; CD4 LYMPHOCYTE COUNT; CYTOPENIA; FOLLOW UP; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; IMMUNE CYTOPENIA; IMMUNOSUPPRESSIVE TREATMENT; INFORMATION RETRIEVAL; LIVER DISEASE; LUPUS VULGARIS; RETROSPECTIVE STUDY; REVIEW; RHEUMATIC DISEASE; SARCOIDOSIS; THYROID DISEASE; VASCULITIS;

AUTOIMMUNITY; HIV; IMMUNOSUPPRESSANT DRUGS;

ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; AUTOIMMUNE DISEASES; FOLLOW-UP STUDIES; FRANCE; HIV INFECTIONS; HUMANS; IMMUNE TOLERANCE;

EID: 84902133064     PISSN: 15689972     EISSN: 18730183     Source Type: Journal    
DOI: 10.1016/j.autrev.2014.04.005     Document Type: Review

References (75)

1. Zandmann-Goddard G., Shoenfeld Y. HIV and autoimmunity. Autoimmun Rev 2002, 1(6):329-337.
2. Stahl D., Lacroix-Desmazes S., Misra N., Karmochkine M., Kaveri S.V., Costagliola D., et al. Alterations of self-reactive antibody repertoires in HIV disease: an insight into the role of T cells in the selection of autoreactive B cells. Immunol Lett 2005, 99(2):198-208.
3. Tsiakalos A., Routsias J.G., Kordossis T., Moutsopoulos H.M., Tzioufas A.G., Sipsas N.V. Fine epitope specificity of anti-erythropoietin antibodies reveals molecular mimicry with HIV-1 p17 protein: a pathogenetic mechanism for HIV-1-related anemia. J Infect Dis 2011, 204(6):902-911.
4. Martinez V., Diemert M.C., Braibant M., Potard V., Charuel J.L., Barin F., et al. Anticardiolipin antibodies in HIV infection are independently associated with antibodies to the membrane proximal external region of gp41 and with cell-associated HIV DNA and immune activation. Clin Infect Dis 2009, 48(1):123-132.
5. Savige J.A., Chang L., Horn S., Crowe S.M. Anti-nuclear, anti-neutrophil cytoplasmic and anti-glomerular basement membrane antibodies in HIV-infected individuals. Autoimmunity 1994, 18(3):205-211.
6. Chetty R. Vasculitides associated with HIV infection. J Clin Pathol 2001, 54(4):275-278.
7. Guillevin L. Vasculitides in the context of HIV infection. AIDS 2008, 22(Suppl. 3):S27-S33.
8. Sambatakou H., Tsiachris D., Stamouli S., Gargalianos P., Archimandritis A. Systemic vasculitis with gastrointestinal involvement in an HIV-infected adult. Am J Med Sci 2008, 335(3):237-238.
9. Matsumoto R., Nakamizo S., Tanioka M., Miyachi Y., Kabashima K. Leukocytoclastic vasculitis with eosinophilic infiltration in an HIV-positive patient. Eur J Dermatol 2011, 21(1):103-104.
10. Chetty R., Batitang S., Nair R. Large artery vasculopathy in HIV-positive patients: another vasculitic enigma. Hum Pathol 2000, 31(3):374-379.
11. Ntusi N.B., Taylor D., Naidoo N.G., Mendelson M. Progressive human immunodeficiency virus-associated vasculopathy: time to revise antiretroviral therapy guidelines?. Cardiovasc J Afr 2011, 22(4):197-200.
12. Ando T., Makuuchi H., Kitanaka Y., Koizumi H. Rupture of a pseudo aneurysm of the abdominal aorta in a patient with human immunodeficiency virus infection. Ann Thorac Cardiovasc Surg 2011, 17(2):198-200.
13. Javed M.A., Sheppard M.N., Pepper J. Aortic root dilation secondary to giant cell aortitis in a human immunodeficiency virus-positive patient. Eur J Cardiothorac Surg 2006, 30(2):400-401.
14. Newsome S.D., Nath A. Varicella-zoster virus vasculopathy and central nervous system immune reconstitution inflammatory syndrome with human immunodeficiency virus infection treated with steroids. J Neurovirol 2009, 15(3):288-291.
15. Soto M.E., Del Carmen Ávila-Casado M., Huesca-Gómez C., Alarcon G.V., Castrejon V., Soto V., et al. Detection of IS6110 and HupB gene sequences of Mycobacterium tuberculosis and bovis in the aortic tissue of patients with Takayasu's arteritis. BMC Infect Dis 2012, 12:194.
16. Massari M., Salvarani C., Portioli I., Ramazzotti E., Gabbi E., Bonazzi L. Polyarteritis nodosa and HIV infection: no evidence of a direct pathogenic role of HIV. Infection 1996, 24(2):159-161.
17. Font C., Miró O., Pedrol E., Masanés F., Coll-Vinent B., Casademont J., et al. Polyarteritis nodosa in human immunodeficiency virus infection: report of four cases and review of the literature. Br J Rheumatol 1996, 35(8):796-799.
18. Angulo J.C., Lopez J.I., Garcia M.E., Peiro J., Flores N. HIV infection presenting as renal polyarteritis nodosa. Int Urol Nephrol 1994, 26(6):637-641.
19. Gajera A., Kais S. HIV polyarteritis nodosa-like vasculitis presenting as chronic abdominal pain. Clin Rheumatol 2009, 28(7):869-872.
20. Chiche L., Jean R., Cretel E., Figuarella-Branger D., Durand J.M. Central nervous system HIV-associated polyarteritis nodosa: long-term outcome. Rev Med Intern 2006, 27(8):625-628.
21. O'Grady N.P., Sears C.L. Therapeutic dilemmas in the care of a human immunodeficiency virus-infected patient with vasculitis: case report. Clin Infect Dis 1996, 23(3):659-661.
22. Lai-Cheong J.E., Tang V., Mazhude C., Baker L., Menagé Hdu P. Highly active antiretroviral therapy: a treatment for cutaneous polyarteritis nodosa-like syndrome in a HIV positive patient?. J Eur Acad Dermatol Venereol 2007, 21(8):1138-1140.
23. Rigante D., Castellazzi L., Bosco A., Esposito S. Is there a crossroad between infections, genetics, and Henoch-Schonlein purpura?. Autoimmun Rev 2013, 12:1016-1021.
24. Hall T.N., Brennan B., Leahy M.F., Woodroffe A.J. Henoch-Schonlein purpura associated with human immunodeficiency virus infection. Nephrol Dial Transplant 1998, 13(4):988-990.
25. Bunupuradah T., Puthanakit T., Pancharoen C., Butterworth O., Phanuphak P., Ananworanich J. Henoch-Schonlein purpura and thrombocytopenia after planned antiretroviral treatment interruption in a Thai girl with HIV infection. Int J Infect Dis 2009, 13(1):e31-e33.
26. Jansen T.L., van Houte D., de Vries T., Wolthuis A. ANCA seropositivity in HIV: a serological pitfall. Neth J Med 2005, 63(7):270-274.
27. Klaassen R.J., Goldschmeding R., Dolman K.M., Vlekke A.B.., Weigel H.M., Eeftinck Schattenkerk J.K., et al. Anti-neutrophil cytoplasmic autoantibodies in patients with symptomatic HIV infection. Clin Exp Immunol 1992, 87(1):24-30.
28. Rodríguez-Pazos L., Gómez-Bernal S., García-Gavín J., Sánchez-Aguilar D., Toribio J. Perifollicular palpable purpura as the initial manifestation of HIV infection. Actas Dermosifiliogr 2010, 101(7):650-652.
29. De Angelis V., Biasinutto C., Pradella P., Vaccher E., Spina M., Tirelli U. Clinical significance of positive direct antiglobulin test in patients with HIV infection. Infection 1994, 22(2):92-95.
30. Lai M., Visconti E., D'Onofrio G., Tamburrini E., Cauda R., Leone G. Lower hemoglobin levels in human immunodeficiency virus-infected patients with a positive direct antiglobulin test (DAT): relationship with DAT strength and clinical stages. Transfusion 2006, 46(7):1237-1243.
31. Koduri P.R., Singa P., Nikolinakos P. Autoimmune hemolytic anemia in patients infected with human immunodeficiency virus-1. Am J Hematol 2002, 70(2):174-176.
32. Sherry N.L., Woolley I.J., Korman T.M. Autoimmune haemolytic anaemia: an unusual presentation of HIV seroconversion disease. AIDS 2010, 24(12):1968-1970.
33. Karpatkin S., Nardi M. Autoimmune anti-HIV-1gp120 antibody with antiidiotype-like activity in sera and immune complexes of HIV-1-related immunologic thrombocytopenia. J Clin Invest 1992, 89(2):356-364.
34. Karpatkin S., Nardi M., Lennette E.T., Byrne B., Poiesz B. Anti-human immunodeficiency virus type 1 antibody complexes on platelets of seropositive thrombocytopenic homosexuals and narcotic addicts. Proc Natl Acad Sci U S A 1988, 85(24):9763-9767.
35. Louache F., Bettaieb A., Henri A., Oksenhendler E., Farcet J.P., Bierling P., et al. Infection of megakaryocytes by human immunodeficiency virus in seropositive patients with immune thrombocytopenic purpura. Blood 1991, 78(7):1697-1705.
36. Li Z., Nardi M.A., Karpatkin S. Role of molecular mimicry to HIV-1 peptides in HIV-1-related immunologic thrombocytopenia. Blood 2005, 106(2):572-576.
37. Ahmad H.N., Ball C., Height S.E., Rees D.C. Rituximab in chronic, recurrent HIV-associated immune thrombocytopenic purpura. Br J Haematol 2004, 127(5):607-608.
38. Arranz Caso J.A., Sanchez Mingo C., Garcia Tena J. Effect of highly active antiretroviral therapy on thrombocytopenia in patients with HIV infection. N Engl J Med 1999, 341(16):1239-1240.
39. Carbonara S., Fiorentino G., Serio G., Maggi P., Ingravallo G., Monno L., et al. Response of severe HIV-associated thrombocytopenia to highly active antiretroviral therapy including protease inhibitors. J Infect 2001, 42(4):251-256.
40. Ananworanich J., Phanuphak N., Nuesch R., Apateerapong W., Rojnuckarin P., Ubolyam S., et al. Recurring thrombocytopenia associated with structured treatment interruption in patients with human immunodeficiency virus infection. Clin Infect Dis 2003, 37(5):723-725.
41. Wang J., Zhang W., Nardi M.A., Li Z. HIV-1 Tat induced-platelet activation and release of CD154 contribute to HIV-1 associated autoimmune thrombocytopenia. J Thromb Haemost 2011, 9(3):562-573.
42. Ambler K.L., Vickars L.M., Leger C.S., Foltz L.M., Montaner J.S., Harris M., et al. Clinical features, treatment, and outcome of HIV-associated immune thrombocytopenia in the HAART era. Adv Hematol 2012, 2012:910954. 10.1155/2012/910954.
43. Miguez M.J., Burbano X., Archer H., Shor-Posner G. Limited impact of highly active antiretroviral therapy in thrombocytopenia. J Acquir Immune Defic Syndr 2002, 30(2):260-261.
44. Ndagijimana J.M., Kroll H., Niehues T. Severe HIV-associated thrombocytopenia despite effective highly active antiretroviral therapy in a vertically infected child. AIDS 2002, 16(5):802-803.
45. Bettaieb A., Fromont P., Louache F., Oksenhendler E., Vainchenker W., Duédari N., et al. Presence of cross-reactive antibody between human immunodeficiency virus (HIV) and platelet glycoproteins in HIV-related immune thrombocytopenic purpura. Blood 1992, 80(1):162-169.
46. Maganti R.M., Reveille J.D., Williams F.M. Therapy insight: the changing spectrum of rheumatic disease in HIV infection. Nat Clin Pract Rheumatol 2008, 4(8):428-438.
47. Calabrese L.H., Kirchner E., Shrestha R. Era of highly active antiretroviral therapy: emergence of a new syndrome of immune reconstitution and changing patterns of disease. Semin Arthritis Rheum 2005, 35(3):166-174.
48. Azeroual A., Harmouche H., Benjilali L., Mezalek Z.T., Adnaoui M., Aouni M., et al. Rheumatoid arthritis associated to HIV infection. Eur J Intern Med 2008, 19(6):e34-e35.
49. Wegrzyn J., Livrozet J.M., Touraine J.L., Miossec P. Rheumatoid arthritis after 9years of human immunodeficiency virus infection: possible contribution of tritherapy. J Rheumatol 2002, 29(10):2232-2234.
50. Rossol M., Pierer M., Arnold S., Keysser G., Burkhardt H., Baerwald C., et al. Negative association of the chemokine receptor CCR5d32 polymorphism with systemic inflammatory response, extra-articular symptoms and joint erosion in rheumatoid arthritis. Arthritis Res Ther 2009, 11(3):R91. 10.1186/ar2733.
51. Romic Z., Derek L., Burek V., Unic A., Serdar T., Marijancevic D., et al. Anti-cyclic citrullinated peptide and rheumatoid factor in HIV positive patients. Rheumatol Int 2011, 31(12):1607-1610.
52. du Toit R., Whitelaw D., Taljaard J.J., du Plessis L., Esser M. Lack of specificity of anticyclic citrullinated peptide antibodies in advanced human immunodeficiency virus infection. J Rheumatol 2011, 38(6):1055-1060.
53. Lambotte O., Ferrari G., Moog C., Yates N.L., Liao H.X., Parks R.J., et al. Heterogeneous neutralizing antibody and antibody-dependent cell cytotoxicity responses in HIV-1 elite controllers. AIDS 2009, 23(8):897-906.
54. Sacilotto Nde C., Yamashiro C.Y., Nishimoto T.M. Juvenile systemic lupus erythematosus in an adolescent with acquired immunodeficiency syndrome. Rev Bras Reumatol 2010, 50(4):467-471.
55. Daikh B.E., Holyst M.M. Lupus-specific autoantibodies in concomitant human immunodeficiency virus and systemic lupus erythematosus: case report and literature review. Semin Arthritis Rheum 2001, 30(6):418-425.
56. Rigante D., Mazzoni M.B., Esposito S. The cryptic interplay between systemic lupus erythematosus and infections. Autoimmun Rev 2014, 13:96-102.
57. Gindea S., Schwartzman J., Herlitz L.C., Rosenberg M., Abadi J., Putterman C. Proliferative glomerulonephritis in lupus patients with human immunodeficiency virus infection: a difficult clinical challenge. Semin Arthritis Rheum 2010, 40(3):201-209.
58. Lenner R., Bregman Z., Teirstein A.S., DePalo L. Recurrent pulmonary sarcoidosis in HIV-infected patients receiving highly active antiretroviral therapy. Chest 2001, 119(3):978-981.
59. Trevenzoli M., Cattelan A.M., Marino F., Marchioro U., Cadrobbi P. Sarcoidosis and HIV infection: a case report and a review of the literature. Postgrad Med J 2003, 79(935):535-538.
60. Miranda E.J., Leite O.H., Duarte M.I. Immune reconstitution inflammatory syndrome associated with pulmonary sarcoidosis in an HIV-infected patient: an immunohistochemical study. Braz J Infect Dis 2011, 15(6):601-606.
61. Jubault V., Penfornis A., Schillo F., Hoen B., Izembart M., Timsit J., et al. Sequential occurrence of thyroid autoantibodies and Graves' disease after immune restoration in severely immunocompromised human immunodeficiency virus-1-infected patients. J Clin Endocrinol Metab 2000, 85(11):4254-4257.
62. Crum N.F., Ganesan A., Johns S.T., Wallace M.R. Graves disease: an increasingly recognized immune reconstitution syndrome. AIDS 2006, 20(3):466-469.
63. Visser R., de Mast Q., Netea-Maier R.T., van der Ven A.J. Hashimoto's thyroiditis presenting as acute painful thyroiditis and as a manifestation of an immune reconstitution inflammatory syndrome in a human immunodeficiency virus-seropositive patient. Thyroid 2012, 22(8):853-855.
64. Chen F., Day S.L., Metcalfe R.A., Sethi G., Kapembwa M.S., Brook M.G., et al. Characteristics of autoimmune thyroid disease occurring as a late complication of immune reconstitution in patients with advanced human immunodeficiency virus (HIV) disease. Medicine (Baltimore) 2005, 84(2):98-106.
65. German V., Vassiloyanakopoulos A., Sampaziotis D., Giannakos G. Autoimmune hepatitis in an HIV infected patient that responded to antiretroviral therapy. Scand J Infect Dis 2005, 37(2):148-151.
66. O'Leary J.G., Zachary K., Misdraji J., Chung R.T. De novo autoimmune hepatitis during immune reconstitution in an HIV-infected patient receiving highly active antiretroviral therapy. Clin Infect Dis 2008, 46(1):e12-e14.
67. Diaz J.S., Octavio J.G., Fernandez-Guerrero M.L. Antiphospholipid syndrome and acute HIV infection. Emerg Infect Dis 2010, 16(2):360-361.
68. Abdollahi A., Morteza A. Serum concentrations of antiphospholipid and anticardiolipin antibodies are higher in HIV-infected women. Rheumatol Int 2012, 32(7):1927-1932.
69. Hassoun A., Al-Kadhimi Z., Cervia J. HIV infection and antiphospholipid antibody: literature review and link to the antiphospholipid syndrome. AIDS Patient Care STDS 2004, 18(6):333-340.
70. McClain M.T., Arbuckle M.R., Heinlen L.D., Dennis G.J., Roebuck J., Rubertone M.V., et al. The prevalence, onset, and clinical significance of antiphospholipid antibodies prior to diagnosis of systemic lupus erythematous. Arthritis Rheum 2004, 50(4):1226-1232.
71. Shen C.Y., Hsieh S.C., Yu C.L., Wang J.Y., Lee L.N., Yu C.J. Autoantibody prevalence in active tuberculosis: reactive or pathognomonic?. BMJ Open 2013, 3(7). [pii: e002665]. 10.1136/bmjopen-2013-002665.
72. Leder A.N., Flansbaum B., Zandman-Goddard G., Asherson R., Shoenfeld Y. Antiphospholipid syndrome induced by HIV. Lupus 2001, 10(5):370-374.
73. Beck-Engeser G.B., Eilat D., Harrer T., Jäck H.M., Wabl M. Early onset of autoimmune disease by the retroviral integrase inhibitor raltegravir. Proc Natl Acad Sci U S A 2009, 106(49):20865-20870.
74. Baroncelli S., Mezzaroma I., Fantauzzi A., Galluzzo C.M., Antoni A.D., Vullo V., et al. No evidence of autoimmune disorders in antiretroviral-experienced HIV-1-infected individuals after long-term treatment with raltegravir. Antivir Ther 2013, 18(3):321-327.
75. Dreyfus D.H. Autoimmune disease: a role for new anti-viral therapies?. Autoimmun Rev 2011, 11:88-97.