Genetic diversity of Streptococcus pneumoniae causing meningitis and sepsis in Singapore during the first year of PCV7 implementation

Emerging Microbes and Infections

Volumn 3, Issue , 2014, Pages

  Jauneikaite, Elita ^a,b   Mary Carnon Jefferies, Johanna ^a,c   William Vere Churton, Nicholas ^a,d   Tzer Pin Lin, Raymond ^e   Lloyd Hibberd, Martin ^b,f   Charles Clarke, Stuart ^a,c,g  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b GENOME INSTITUTE OF SINGAPORE   (Singapore)

^c University Hospital Southampton NHS Foundation Trust   (United Kingdom)

^d UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^e MINISTRY OF HEALTH   (Singapore)

^f LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^g PUBLIC HEALTH ENGLAND   (United Kingdom)

Author keywords

capsular type; invasive pneumococcal disease; multilocus sequence typing; Singapore; Streptococcus pneumoniae; vaccine

Indexed keywords

PNEUMOCOCCUS VACCINE; BACTERIAL DNA;

ALLELE; ARTICLE; BACTERIAL GENETICS; BACTERIUM ISOLATE; DRUG EFFICACY; GENETIC VARIABILITY; MULTILOCUS SEQUENCE TYPING; NONHUMAN; PNEUMOCOCCAL INFECTION; PRIORITY JOURNAL; SEROTYPE; SEROTYPING; SINGAPORE; STREPTOCOCCUS PNEUMONIAE; STREPTOCOCCUS PNEUMONIAE SEROTYPE 1; STREPTOCOCCUS PNEUMONIAE SEROTYPE 11; STREPTOCOCCUS PNEUMONIAE SEROTYPE 12; STREPTOCOCCUS PNEUMONIAE SEROTYPE 14; STREPTOCOCCUS PNEUMONIAE SEROTYPE 15A; STREPTOCOCCUS PNEUMONIAE SEROTYPE 15B; STREPTOCOCCUS PNEUMONIAE SEROTYPE 15C; STREPTOCOCCUS PNEUMONIAE SEROTYPE 18F; STREPTOCOCCUS PNEUMONIAE SEROTYPE 19A; STREPTOCOCCUS PNEUMONIAE SEROTYPE 19F; STREPTOCOCCUS PNEUMONIAE SEROTYPE 20; STREPTOCOCCUS PNEUMONIAE SEROTYPE 22; STREPTOCOCCUS PNEUMONIAE SEROTYPE 23A; STREPTOCOCCUS PNEUMONIAE SEROTYPE 23F; STREPTOCOCCUS PNEUMONIAE SEROTYPE 3; STREPTOCOCCUS PNEUMONIAE SEROTYPE 34; STREPTOCOCCUS PNEUMONIAE SEROTYPE 4; STREPTOCOCCUS PNEUMONIAE SEROTYPE 6A; STREPTOCOCCUS PNEUMONIAE SEROTYPE 6B; STREPTOCOCCUS PNEUMONIAE SEROTYPE 6C; STREPTOCOCCUS PNEUMONIAE SEROTYPE 7F; STREPTOCOCCUS PNEUMONIAE SEROTYPE 8; STREPTOCOCCUS PNEUMONIAE SEROTYPE 9V; STREPTOCOCCUS PNEUMONIAE SEROTYPE NT; STREPTOCOCCUS PNEUMONIAE SEROTYPE UC; ADULT; AGED; BACTERIUM CULTURE; CEREBROSPINAL FLUID; CHILD; CONJUGATION; CROSS PROTECTION; DISEASE SURVEILLANCE; DNA EXTRACTION; HUMAN; INFECTION PREVENTION; MAJOR CLINICAL STUDY; MIDDLE AGED; MOLECULAR EPIDEMIOLOGY; PNEUMOCOCCAL MENINGITIS; PRESCHOOL CHILD; SEPSIS; VACCINATION; YOUNG ADULT;

STREPTOCOCCUS PNEUMONIAE;

EID: 84902096194     PISSN: None     EISSN: 22221751     Source Type: Journal    
DOI: 10.1038/emi.2014.37     Document Type: Article

References (37)

1. World Health Organization. Pneumococcal conjugate vaccine for childhoodimmunization-WHO position paper. Weekly Epidemiological Record. Geneva:WHO, 2007. Available at http://www.who.int/wer/2007/wer8212. pdfua51(accessed 23 May 2011).
2. Feikin DR, Klugman KP, Facklam RR, Zell ER, Schuchat A, Whitney CG. Increasedprevalence of pediatric pneumococcal serotypes in elderly adults. Clin Infect Dis2005; 41: 481-487.
3. Hausdorff WP, Feikin DR, Klugman KP. Epidemiological differences amongpneumococcal serotypes. Lancet Infect Dis 2005; 5: 83-93.
4. Chong CY, Koh-Cheng T, Yee-Hui M, Nancy TW. Invasive pneumococcal disease inSingapore children. Vaccine 2008; 26: 3427-3431.
5. Hsu LY, Lui SW, Lee JL et al. Adult invasive pneumococcal disease pre-and peripneumococcalconjugate vaccine introduction in a tertiary hospital in Singapore.J Med Microbiol 2009; 58 (Pt 1): 101-104.
6. Low S, Chan FL, Cutter J,Ma S, Goh KT, Chew SK. A national study of the epidemiologyof pneumococcal disease among hospitalised patients in Singapore: 1995 to 2004.Singapore Med J 2007; 48: 824-829.
7. Soh SW, Poh CL, Lin RV. Serotype distribution and antimicrobial resistance ofStreptococcus pneumoniae isolates from pediatric patients in Singapore.Antimicrob Agents Chemother 2000; 44: 2193-2196.
8. Jefferies JM, Tee WS, Clarke SC. Molecular analysis of Streptococcus pneumoniaeclones causing invasive disease in children in Singapore. J Med Microbiol 2011; 60(Pt 6): 750-755.
9. Koh TH, Sng LH, Ngan CC. Molecular typing of multiresistant Streptococcuspneumoniae serogroup 19 in Singapore. Pathology 1998; 30: 395-398.
10. La MV, Siti Zulaina MS, Chua R, Tee WS, Lin RV. Pneumococcal serotyping forsurveillance of invasive pneumococcal diseases in Singapore, 2010-2011. EpidemiolNews Bull 2012; 38: 29-35. Singapore: Ministry of Health, 2012. Available at https://www.moh.gov.sg/content/dam/moh-web/Statistics/ Epidemiological-News-Bulletin/2012/ENB02Q-12.pdf (accessed 23 May 2012).
11. Vasoo S, Singh K, Chow C, Lin RT, Hsu LY, Tambyah PA. Pneumococcal carriage andresistance in children attending day care centers in Singapore in an early era of PCV-7uptake. J Infect 2010; 60: 507-509.
12. Lin TY, Shah NK, Brooks D, Garcia CS. Summary of invasive pneumococcal diseaseburden among children in the Asia-Pacific region. Vaccine 2010; 28: 7589-7605.
13. World Health Organization. Country health profile-Singapore. Geneva: WHO, 2012.Available at http://www.who.int/countries/sgp/en/(accessed 23 May 2012).
14. Ministry of Health Singapore. Pneumococcal disease. Singapore: Ministry of Health,2012. Available at http://www.hpb.gov.sg/HOPPortal/dandc-article/8314 (accessed23 May 2012).
15. Ministry of Health Singapore. Communicable disease surveillance in Singapore 2012.Childhood immunisation. Singapore: Ministry of Health, 2014. Available at http://www.moh.gov.sg/content/dam/moh-web/Publications/Reports/ 2013/Childhood%20Immunisation.pdf (accessed 24 February 2014).
16. Tan TQ. Pediatric invasive pneumococcal disease in the United States in the era ofpneumococcal conjugate vaccines. Clin Microbiol Rev 2012; 25: 409-419.
17. Brueggemann AB, Griffiths DT, Meats E, Peto T, Crook DW, Spratt BG. Clonalrelationships between invasive and carriage Streptococcus pneumoniae andserotype-and clone-specific differences in invasive disease potential. J Infect Dis2003; 187: 1424-1432.
18. Pai R, Moore MR, Pilishvili T, Gertz RE, Whitney CG, Beall B. Postvaccine geneticstructure of Streptococcus pneumoniae serotype 19A from children in the UnitedStates. J Infect Dis 2005; 192: 1988-1995.
19. Tocheva AS, Jefferies JM, Christodoulides M, Faust SN, Clarke SC. Increase inserotype 6C pneumococcal carriage, United Kingdom. Emerg Infect Dis 2010; 16:154-155.
20. Battig P, Hathaway LJ, Hofer S, Muhlemann K. Serotype-specific invasiveness andcolonization prevalence in Streptococcus pneumoniae correlate with the lag phaseduring in vitro growth. Microbes Infect 2006; 8: 2612-2617.
21. Hanage WP, Kaijalainen TH, SyrjanenRKet al. Invasiveness of serotypes and clones ofStreptococcus pneumoniae among children in Finland. InfectImmun2005; 73: 431-435.
22. Kronenberg A, Zucs P, Droz S, Muhlemann K. Distribution and invasiveness ofStreptococcus pneumoniae serotypes in Switzerland, a country with low antibioticselection pressure, from 2001 to 2004. J Clin Microbiol 2006; 44: 2032-2038.
23. Enright MC, Spratt BG. A multilocus sequence typing scheme for Streptococcuspneumoniae: identification of clones associated with serious invasive disease.Microbiology 1998; 144 (Pt 11): 3049-3060.
24. Sorensen UB. Typing of pneumococci by using 12 pooled antisera. J Clin Microbiol1993; 31: 2097-2100.
25. Centers for Disease Control and prevention. PCR deduction of pneumococcalserotypes. Atlanta: CDC, 2012. Available at http://www.cdc.gov/ ncidod/biotech/strep/pcr.htm (accessed 8 July 2012).
26. MLST database. Streptococcus pneumoniae. London: Imperial College London,2012. Available at http://spneumoniae.mlst.net/(accessed 23 May 2012).
27. Francisco AP, Vaz C, Monteiro PT, Melo-Cristino J, RamirezM, Carrico JA. PHYLOViZ:phylogenetic inference and data visualization for sequence based typing methods.BMC Bioinformatics 2012;13: 87.
28. Simpson EH. Measurement of diversity. Nature 1949; 163: 688.
29. Park IH, Moore MR, Treanor JJ et al. Differential effects of pneumococcal vaccinesagainst serotypes 6A and 6C. J Infect Dis 2008; 198: 1818-1822.
30. McGee L, McDougal L, Zhou J et al. Nomenclature of major antimicrobial-resistantclones of Streptococcus pneumoniae defined by the pneumococcal molecularepidemiology network. J Clin Microbiol 2001; 39: 2565-2571.
31. Lexau CA, Lynfield R, DanilaRet al. Changing epidemiology of invasive pneumococcaldisease among older adults in the era of pediatric pneumococcal conjugate vaccine.JAMA 2005; 294: 2043-2051.
32. Pilishvili T, Lexau C, FarleyMMet al. Sustained reductions in invasive pneumococcaldisease in the era of conjugate vaccine. J Infect Dis 2010; 201: 32-41.
33. Rodrigo C, Bewick T, Sheppard C et al. Pneumococcal serotypes in adult non-invasiveand invasive pneumonia in relation to child contact and child vaccination status.Thorax 2014; 69: 168-173.
34. Thoon KC, Chong CY, Tee NW. Early impact of pneumococcal conjugate vaccine oninvasive pneumococcal disease in Singapore children, 2005 through 2010. Int JInfect Dis 2012; 16: e209-e215.
35. Jauneikaite E, Jefferies JM, Hibberd ML, Clarke SC. Prevalence of Streptococcuspneumoniae serotypes causing invasive and non-invasive disease in South EastAsia: a review. Vaccine 2012; 30: 3503-3514.
36. Beall BW, Gertz RE, Hulkower RL, Whitney CG, Moore MR, Brueggemann AB. Shiftinggenetic structure of invasive serotype 19A pneumococci in the United States. J InfectDis 2011; 203: 1360-1368.
37. Shin J, Baek JY, Kim SH, Song JH, Ko KS. Predominance of ST320 amongStreptococcus pneumoniae serotype 19A isolates from 10 Asian countries.J Antimicrob Chemother 2011; 66: 1001-1004