Molecular characterization of Klebsiella pneumoniae isolated from renal transplanted patients: Virulence markers, extended-spectrum β-lactamases, and genetic relatedness

Diagnostic Microbiology and Infectious Disease

Volumn 79, Issue 3, 2014, Pages 393-395

  Calhau, Vera ^a,b   Boaventura, Luísa ^b   Ribeiro, Graça ^b   Mendonça, Nuno ^a   Da Silva, Gabriela J ^a  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b CENTRO HOSPITALAR E UNIVERSITÁRIO DE COIMBRA   (Portugal)

Author keywords

CTX M 15; Pathogenicity island; Plasmid replicon typing; Virulence factors

Indexed keywords

AMPICILLIN; BETA LACTAMASE CTX M; BETA LACTAMASE SHV; CEFOTAXIME; CEFTAZIDIME; CIPROFLOXACIN; COTRIFAMOLE; ERTAPENEM; EXTENDED SPECTRUM BETA LACTAMASE; GENTAMICIN; LEVOFLOXACIN; MEROPENEM; SIDEROPHORE; BETA LACTAMASE; VIRULENCE FACTOR;

ALLS GENE; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM ISOLATE; CF29A GENE; CONTROLLED STUDY; FIMH GENE; GENE FUNCTION; GENETIC LINKAGE; HOSPITAL ADMISSION; HUMAN; KFU GENE; KIDNEY TRANSPLANTATION; KLEBSIELLA PNEUMONIAE; MOLECULAR CLONING; MRKD GENE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RMPA GENE; SURGICAL PATIENT; UGE GENE; UREA GENE; WABG GENE; CLASSIFICATION; GENETICS; GRAFT RECIPIENT; ISOLATION AND PURIFICATION; KLEBSIELLA INFECTION; MICROBIOLOGY; MOLECULAR TYPING; PLASMID;

BETA-LACTAMASES; HUMANS; KIDNEY TRANSPLANTATION; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; MOLECULAR TYPING; PLASMIDS; TRANSPLANT RECIPIENTS; VIRULENCE FACTORS;

EID: 84902086942     PISSN: 07328893     EISSN: 18790070     Source Type: Journal    
DOI: 10.1016/j.diagmicrobio.2013.08.031     Document Type: Article

References (11)

1. Brisse S., Fevre C., Passet V., Issenhuth-Jeanjean S., Tournebize R., Diancourt L., et al. Virulent clones of Klebsiella pneumoniae: identification and evolutionary scenario based on genomic and phenotypic characterization. PLoS One 2009, 4:e4982.
2. Bronowski C., Smith S.L., Yokota K., Corkill J.E., Martin H.M., Campbell B.J., et al. A subset of mucosa-associated Escherichia coli isolates from patients with colon cancer, but not Crohn's disease, share pathogenicity islands with urinary pathogenic E. coli. Microbiology 2008, 154:571-583.
3. Carattoli A. Plasmids in Gram negatives: molecular typing of resistance plasmids. Int J Med Microbiol 2011, 301:654-658.
4. Carattoli A., Bertini A., Villa L., Falbo V., Hopkins K.L., Threlfall E.J. Identification of plasmids by PCR-based replicon typing. J Microbiol Methods 2005, 63:219-228.
5. Coelho A., González-López J.J., Miró E., Alonso-Tarrés C., Mirelis B., Larrosa M.N., et al. Characterisation of the CTX-M-15-encoding gene in Klebsiella pneumoniae strains from the Barcelona metropolitan area: plasmid diversity and chromosomal integration. Int J Antimicrob Agents 2010, 36:73-78.
6. Conceição T., Brízio A., Duarte A., Lito L.M., Cristino J.M., Salgado M.J. First description of CTX-M-15-producing Klebsiella pneumoniae in Portugal. Antimicrob Agents Chemother 2005, 49:477-478.
7. Koczura R., Kaznowski A. Occurrence of the Yersinia high-pathogenicity island and iron uptake systems in clinical isolates of Klebsiella pneumoniae. Microb Pathog 2003, 35:197-202.
8. Machado P., Silva A., Lito L., Melo-Cristino J., Duarte A. Emergence of Klebsiella pneumoniae ST11-producing KPC-3 carbapenemase at a Lisbon hospital. Clin Microbiol Infect 2010, 16(Suppl. 2):S28.
9. Mendonça N., Ferreira E., Louro D., Caniça M. Molecular epidemiology and producing Klebsiella pneumoniae isolated in Portugal. Int J Antimicrob Agents 2009, 34:29-37.
10. Sabaté M., Moreno E., Pérez T., Andreu A., Prats G. Pathogenicity island markers in commensal and uropathogenic Escherichia coli isolates. Clin Microbiol Infect 2006, 12:880-886.
11. Turton J.F., Perry C., Elgohari S., Hampton C.V. PCR characterization and typing of Klebsiella pneumoniae using capsular type-specific, variable number tandem repeat and virulence gene targets. J Med Microbiol 2010, 59:541-547.