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Volumn 32, Issue 31, 2014, Pages 3909-3916

Oral immunization with Lactococcus lactis-expressing EspB induces protective immune responses against Escherichia coli O157: H7 in a murine model of colonization

Author keywords

Enterohemorrhagic Escherichia coli; EspB; Hemolytic uremic syndrome; Lactococcus lactis; Oral vaccination

Indexed keywords

BACTERIAL PROTEIN; ESCHERICHIA COLI VACCINE; ESPB PROTEIN; GAMMA INTERFERON; IMMUNOGLOBULIN A; INTERLEUKIN 10; INTERLEUKIN 4; UNCLASSIFIED DRUG; BACTERIUM ANTIBODY; CYTOKINE; EAEB PROTEIN, E COLI; ESCHERICHIA COLI PROTEIN; OUTER MEMBRANE PROTEIN;

EID: 84902011138     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2014.05.054     Document Type: Article
Times cited : (33)

References (64)
  • 1
    • 0026398187 scopus 로고
    • The epidemiology of infections caused by Escherichia coli O157:H7, other enterohemorrhagic E. coli, and the associated hemolytic uremic syndrome
    • Griffin P.M., Tauxe R.V. The epidemiology of infections caused by Escherichia coli O157:H7, other enterohemorrhagic E. coli, and the associated hemolytic uremic syndrome. Epidemiol Rev 1991, 13:60-98.
    • (1991) Epidemiol Rev , vol.13 , pp. 60-98
    • Griffin, P.M.1    Tauxe, R.V.2
  • 2
    • 0041411080 scopus 로고    scopus 로고
    • Effect of an oral Shiga toxin-binding agent on diarrhea-associated hemolytic uremic syndrome in children: a randomized controlled trial
    • (the journal of the American Medical Association)
    • Trachtman H., Cnaan A., Christen E., Gibbs K., Zhao S., Acheson D.W., et al. Effect of an oral Shiga toxin-binding agent on diarrhea-associated hemolytic uremic syndrome in children: a randomized controlled trial. JAMA 2003, 290:1337-1344. (the journal of the American Medical Association).
    • (2003) JAMA , vol.290 , pp. 1337-1344
    • Trachtman, H.1    Cnaan, A.2    Christen, E.3    Gibbs, K.4    Zhao, S.5    Acheson, D.W.6
  • 3
    • 0023617473 scopus 로고
    • A severe outbreak of Escherichia coli O157:H7-associated hemorrhagic colitis in a nursing home
    • Carter A.O., Borczyk A.A., Carlson J.A., Harvey B., Hockin J.C., Karmali M.A., et al. A severe outbreak of Escherichia coli O157:H7-associated hemorrhagic colitis in a nursing home. N Engl J Med 1987, 317:1496-1500.
    • (1987) N Engl J Med , vol.317 , pp. 1496-1500
    • Carter, A.O.1    Borczyk, A.A.2    Carlson, J.A.3    Harvey, B.4    Hockin, J.C.5    Karmali, M.A.6
  • 4
    • 36549081013 scopus 로고    scopus 로고
    • Pathogenesis and treatment of Shiga toxin-producing Escherichia coli infections
    • Serna A., Boedeker E.C. Pathogenesis and treatment of Shiga toxin-producing Escherichia coli infections. Curr Opin Gastroenterol 2008, 24:38-47.
    • (2008) Curr Opin Gastroenterol , vol.24 , pp. 38-47
    • Serna, A.1    Boedeker, E.C.2
  • 5
    • 0025344791 scopus 로고
    • Hemolytic-uremic syndrome during an outbreak of Escherichia coli O157:H7 infections in institutions for mentally retarded persons: clinical and epidemiologic observations
    • Pavia A.T., Nichols C.R., Green D.P., Tauxe R.V., Mottice S., Greene K.D., et al. Hemolytic-uremic syndrome during an outbreak of Escherichia coli O157:H7 infections in institutions for mentally retarded persons: clinical and epidemiologic observations. J Pediatr 1990, 116:544-551.
    • (1990) J Pediatr , vol.116 , pp. 544-551
    • Pavia, A.T.1    Nichols, C.R.2    Green, D.P.3    Tauxe, R.V.4    Mottice, S.5    Greene, K.D.6
  • 6
    • 0034729744 scopus 로고    scopus 로고
    • The risk of the hemolytic-uremic syndrome after antibiotic treatment of Escherichia coli O157:H7 infections
    • Wong C.S., Jelacic S., Habeeb R.L., Watkins S.L., Tarr P.I. The risk of the hemolytic-uremic syndrome after antibiotic treatment of Escherichia coli O157:H7 infections. N Engl J Med 2000, 342:1930-1936.
    • (2000) N Engl J Med , vol.342 , pp. 1930-1936
    • Wong, C.S.1    Jelacic, S.2    Habeeb, R.L.3    Watkins, S.L.4    Tarr, P.I.5
  • 7
    • 84862159579 scopus 로고    scopus 로고
    • Risk factors for the hemolytic uremic syndrome in children infected with Escherichia coli O157:H7: a multivariable analysis
    • Wong C.S., Mooney J.C., Brandt J.R., Staples A.O., Jelacic S., Boster D.R., et al. Risk factors for the hemolytic uremic syndrome in children infected with Escherichia coli O157:H7: a multivariable analysis. Clin Infect Dis 2012, 55:33-41.
    • (2012) Clin Infect Dis , vol.55 , pp. 33-41
    • Wong, C.S.1    Mooney, J.C.2    Brandt, J.R.3    Staples, A.O.4    Jelacic, S.5    Boster, D.R.6
  • 8
    • 77952721685 scopus 로고    scopus 로고
    • Cytoskeleton-modulating effectors of enteropathogenic and enterohemorrhagic Escherichia coli
    • Hamada D. Cytoskeleton-modulating effectors of enteropathogenic and enterohemorrhagic Escherichia coli. FEBS J 2010, 277:2389.
    • (2010) FEBS J , vol.277 , pp. 2389
    • Hamada, D.1
  • 10
    • 0036227734 scopus 로고    scopus 로고
    • The EspB protein of enterohaemorrhagic Escherichia coli interacts directly with alpha-catenin
    • Kodama T., Akeda Y., Kono G., Takahashi A., Imura K., Iida T., et al. The EspB protein of enterohaemorrhagic Escherichia coli interacts directly with alpha-catenin. Cell Microbiol 2002, 4:213-222.
    • (2002) Cell Microbiol , vol.4 , pp. 213-222
    • Kodama, T.1    Akeda, Y.2    Kono, G.3    Takahashi, A.4    Imura, K.5    Iida, T.6
  • 11
    • 3343020727 scopus 로고    scopus 로고
    • Alpha 1-antitrypsin binds to and interferes with functionality of EspB from atypical and typical enteropathogenic Escherichia coli strains
    • Knappstein S., Ide T., Schmidt M.A., Heusipp G. Alpha 1-antitrypsin binds to and interferes with functionality of EspB from atypical and typical enteropathogenic Escherichia coli strains. Infect Immun 2004, 72:4344-4350.
    • (2004) Infect Immun , vol.72 , pp. 4344-4350
    • Knappstein, S.1    Ide, T.2    Schmidt, M.A.3    Heusipp, G.4
  • 12
    • 36749001580 scopus 로고    scopus 로고
    • The enteropathogenic E. coli effector EspB facilitates microvillus effacing and antiphagocytosis by inhibiting myosin function
    • Iizumi Y., Sagara H., Kabe Y., Azuma M., Kume K., Ogawa M., et al. The enteropathogenic E. coli effector EspB facilitates microvillus effacing and antiphagocytosis by inhibiting myosin function. Cell Host Microbe. 2007, 2:383-392.
    • (2007) Cell Host Microbe. , vol.2 , pp. 383-392
    • Iizumi, Y.1    Sagara, H.2    Kabe, Y.3    Azuma, M.4    Kume, K.5    Ogawa, M.6
  • 13
    • 79960124679 scopus 로고    scopus 로고
    • Serological response of Shiga toxin-producing Escherichia coli type III secreted proteins in sera from vaccinated rabbits, naturally infected cattle, and humans
    • Asper D.J., Karmali M.A., Townsend H., Rogan D., Potter A.A. Serological response of Shiga toxin-producing Escherichia coli type III secreted proteins in sera from vaccinated rabbits, naturally infected cattle, and humans. Clin Vaccine Immunol: CVI 2011, 18:1052-1057.
    • (2011) Clin Vaccine Immunol: CVI , vol.18 , pp. 1052-1057
    • Asper, D.J.1    Karmali, M.A.2    Townsend, H.3    Rogan, D.4    Potter, A.A.5
  • 14
    • 0033860736 scopus 로고    scopus 로고
    • Human response to Escherichia coli O157:H7 infection: antibodies to secreted virulence factors
    • Li Y., Frey E., Mackenzie A.M., Finlay B.B. Human response to Escherichia coli O157:H7 infection: antibodies to secreted virulence factors. Infect Immun 2000, 68:5090-5095.
    • (2000) Infect Immun , vol.68 , pp. 5090-5095
    • Li, Y.1    Frey, E.2    Mackenzie, A.M.3    Finlay, B.B.4
  • 15
    • 0036935621 scopus 로고    scopus 로고
    • Antibodies to intimin and Escherichia coli secreted proteins A and B in patients with enterohemorrhagic Escherichia coli infections
    • Karpman D., Bekassy Z.D., Sjogren A.C., Dubois M.S., Karmali M.A., Mascarenhas M., et al. Antibodies to intimin and Escherichia coli secreted proteins A and B in patients with enterohemorrhagic Escherichia coli infections. Pediatr Nephrol 2002, 17:201-211.
    • (2002) Pediatr Nephrol , vol.17 , pp. 201-211
    • Karpman, D.1    Bekassy, Z.D.2    Sjogren, A.C.3    Dubois, M.S.4    Karmali, M.A.5    Mascarenhas, M.6
  • 16
    • 52949113396 scopus 로고    scopus 로고
    • Efficient immune responses against Intimin and EspB of enterohaemorragic Escherichia coli after intranasal vaccination using the TLR2/6 agonist MALP-2 as adjuvant
    • Cataldi A., Yevsa T., Vilte D.A., Schulze K., Castro-Parodi M., Larzabal M., et al. Efficient immune responses against Intimin and EspB of enterohaemorragic Escherichia coli after intranasal vaccination using the TLR2/6 agonist MALP-2 as adjuvant. Vaccine 2008, 26:5662-5667.
    • (2008) Vaccine , vol.26 , pp. 5662-5667
    • Cataldi, A.1    Yevsa, T.2    Vilte, D.A.3    Schulze, K.4    Castro-Parodi, M.5    Larzabal, M.6
  • 17
    • 33644836224 scopus 로고    scopus 로고
    • Mucosal vaccines: the promise and the challenge
    • Neutra M.R., Kozlowski P.A. Mucosal vaccines: the promise and the challenge. Nat Rev Immunol 2006, 6:148-158.
    • (2006) Nat Rev Immunol , vol.6 , pp. 148-158
    • Neutra, M.R.1    Kozlowski, P.A.2
  • 19
    • 84864338756 scopus 로고    scopus 로고
    • Recent progress in mucosal vaccine development: potential and limitations
    • Lycke N. Recent progress in mucosal vaccine development: potential and limitations. Nat Rev Immunol 2012, 12:592-605.
    • (2012) Nat Rev Immunol , vol.12 , pp. 592-605
    • Lycke, N.1
  • 20
    • 84869054314 scopus 로고    scopus 로고
    • Lactic acid bacteria as oral delivery systems for biomolecules
    • Berlec A., Ravnikar M., Strukelj B. Lactic acid bacteria as oral delivery systems for biomolecules. Pharmazie 2012, 67:891-898.
    • (2012) Pharmazie , vol.67 , pp. 891-898
    • Berlec, A.1    Ravnikar, M.2    Strukelj, B.3
  • 21
    • 84860833653 scopus 로고    scopus 로고
    • Development of vaccine delivery vehicles based on lactic acid bacteria
    • Tarahomjoo S. Development of vaccine delivery vehicles based on lactic acid bacteria. Mol Biotechnol 2012, 51:183-199.
    • (2012) Mol Biotechnol , vol.51 , pp. 183-199
    • Tarahomjoo, S.1
  • 22
    • 79960016255 scopus 로고    scopus 로고
    • Mucosal vaccination and therapy with genetically modified lactic acid bacteria
    • Wells J. Mucosal vaccination and therapy with genetically modified lactic acid bacteria. Annu Rev Food Sci Technol 2011, 2:423-445.
    • (2011) Annu Rev Food Sci Technol , vol.2 , pp. 423-445
    • Wells, J.1
  • 23
    • 84875552700 scopus 로고    scopus 로고
    • Mucosal priming of the murine immune system against enterohemorrhagic Escherichia coli O157:H7 using Lactococcus lactis expressing the type III secretion system protein EspB
    • Ahmed B., Loos M., Vanrompay D., Cox E. Mucosal priming of the murine immune system against enterohemorrhagic Escherichia coli O157:H7 using Lactococcus lactis expressing the type III secretion system protein EspB. Vet Immunol Immunopathol 2013, 152:141-145.
    • (2013) Vet Immunol Immunopathol , vol.152 , pp. 141-145
    • Ahmed, B.1    Loos, M.2    Vanrompay, D.3    Cox, E.4
  • 24
    • 0027230871 scopus 로고
    • Improved cloning vectors and transformation procedure for Lactococcus lactis
    • Wells J.M., Wilson P.W., Lepage R.W.F. Improved cloning vectors and transformation procedure for Lactococcus lactis. J Appl Bacteriol 1993, 74:629-636.
    • (1993) J Appl Bacteriol , vol.74 , pp. 629-636
    • Wells, J.M.1    Wilson, P.W.2    Lepage, R.W.F.3
  • 25
    • 0034556237 scopus 로고    scopus 로고
    • Secretion of biologically active murine interleukin-10 by Lactococcus lactis
    • Schotte L., Steidler L., Vandekerckhove J., Remaut E. Secretion of biologically active murine interleukin-10 by Lactococcus lactis. Enzyme Microb Technol 2000, 27:761-765.
    • (2000) Enzyme Microb Technol , vol.27 , pp. 761-765
    • Schotte, L.1    Steidler, L.2    Vandekerckhove, J.3    Remaut, E.4
  • 26
    • 0035863886 scopus 로고    scopus 로고
    • Chemokine receptor expression and function in CD4(+) T lymphocytes with regulatory activity
    • Sebastiani S., Allavena P., Albanesi C., Nasorri F., Bianchi G., Traidl C., et al. Chemokine receptor expression and function in CD4(+) T lymphocytes with regulatory activity. J Immunol 2001, 166:996-1002.
    • (2001) J Immunol , vol.166 , pp. 996-1002
    • Sebastiani, S.1    Allavena, P.2    Albanesi, C.3    Nasorri, F.4    Bianchi, G.5    Traidl, C.6
  • 27
    • 0025370411 scopus 로고
    • Mouse model for colonization and disease caused by enterohemorrhagic Escherichia coli O157-H7
    • Wadolkowski E.A., Burris J.A., Obrien A.D. Mouse model for colonization and disease caused by enterohemorrhagic Escherichia coli O157-H7. Infect Immun 1990, 58:2438-2445.
    • (1990) Infect Immun , vol.58 , pp. 2438-2445
    • Wadolkowski, E.A.1    Burris, J.A.2    Obrien, A.D.3
  • 28
    • 78650556001 scopus 로고    scopus 로고
    • Rectal inoculation of sheep with E. coli O157:H7 results in persistent infection in the absence of a protective immune response
    • Vandewalle K., Atefyekta M., Verdonck F., De Zutter L., Cox E. Rectal inoculation of sheep with E. coli O157:H7 results in persistent infection in the absence of a protective immune response. Vet Microbiol 2011, 147:376-382.
    • (2011) Vet Microbiol , vol.147 , pp. 376-382
    • Vandewalle, K.1    Atefyekta, M.2    Verdonck, F.3    De Zutter, L.4    Cox, E.5
  • 29
    • 0036284984 scopus 로고    scopus 로고
    • The role of Th1/Th2 polarization in mucosal immunity
    • Neurath M.F., Finotto S., Glimcher L.H. The role of Th1/Th2 polarization in mucosal immunity. Nat Med 2002, 8:567-573.
    • (2002) Nat Med , vol.8 , pp. 567-573
    • Neurath, M.F.1    Finotto, S.2    Glimcher, L.H.3
  • 30
    • 77649184739 scopus 로고    scopus 로고
    • The regulation of IL-10 production by immune cells
    • Saraiva M., O'Garra A. The regulation of IL-10 production by immune cells. Nat Rev Immunol 2010, 10:170-181.
    • (2010) Nat Rev Immunol , vol.10 , pp. 170-181
    • Saraiva, M.1    O'Garra, A.2
  • 31
    • 0032920907 scopus 로고    scopus 로고
    • ClpP participates in the degradation of misfolded protein in Lactococcus lactis
    • Frees D., Ingmer H. ClpP participates in the degradation of misfolded protein in Lactococcus lactis. Microbiol Biotechnol 1999, 31:79-87.
    • (1999) Microbiol Biotechnol , vol.31 , pp. 79-87
    • Frees, D.1    Ingmer, H.2
  • 32
    • 0028135021 scopus 로고
    • A Lactococcus lactis gene encodes a membrane-protein with putative ATPase activity that is homologous to the essential Escherichia coli Ftsh gene-product
    • Nilsson D., Lauridsen A.A., Tomoyasu T., Ogura T. A Lactococcus lactis gene encodes a membrane-protein with putative ATPase activity that is homologous to the essential Escherichia coli Ftsh gene-product. Microbiology-UK 1994, 140:2601-2610.
    • (1994) Microbiology-UK , vol.140 , pp. 2601-2610
    • Nilsson, D.1    Lauridsen, A.A.2    Tomoyasu, T.3    Ogura, T.4
  • 33
    • 0031876826 scopus 로고    scopus 로고
    • Induced levels of heat shock proteins in a DNAK mutant of Lactococcus lactis
    • Koch B., Kilstrup M., Vogensen F.K., Hammer K. Induced levels of heat shock proteins in a DNAK mutant of Lactococcus lactis. J Bacteriol 1998, 180:3873-3881.
    • (1998) J Bacteriol , vol.180 , pp. 3873-3881
    • Koch, B.1    Kilstrup, M.2    Vogensen, F.K.3    Hammer, K.4
  • 34
    • 0041707634 scopus 로고    scopus 로고
    • Controlled intra- or extracellular production of staphylococcal nuclease and ovine omega interferon in Lactococcus lactis
    • Bermudez-Humaran L.G., Langella P., Commissaire J., Gilbert S., Le Loir Y., L'Haridon R., et al. Controlled intra- or extracellular production of staphylococcal nuclease and ovine omega interferon in Lactococcus lactis. FEMS Microbiol Lett 2003, 224:307-313.
    • (2003) FEMS Microbiol Lett , vol.224 , pp. 307-313
    • Bermudez-Humaran, L.G.1    Langella, P.2    Commissaire, J.3    Gilbert, S.4    Le Loir, Y.5    L'Haridon, R.6
  • 35
    • 0036151762 scopus 로고    scopus 로고
    • Production and targeting of the Brucella abortus antigen L7/L12 in Lactococcus lactis: a first step towards food-grade live vaccines against brucellosis
    • Ribeiro L.A., Azevedo V., Le Loir Y., Oliveira S.C., Dieye Y., Piard J.C., et al. Production and targeting of the Brucella abortus antigen L7/L12 in Lactococcus lactis: a first step towards food-grade live vaccines against brucellosis. Appl Environ Microbiol 2002, 68:910-916.
    • (2002) Appl Environ Microbiol , vol.68 , pp. 910-916
    • Ribeiro, L.A.1    Azevedo, V.2    Le Loir, Y.3    Oliveira, S.C.4    Dieye, Y.5    Piard, J.C.6
  • 37
    • 0032729983 scopus 로고    scopus 로고
    • Survival, physiology, and lysis of Lactococcus lactis in the digestive tract
    • Drouault S., Corthier G., Ehrlich S.D., Renault P. Survival, physiology, and lysis of Lactococcus lactis in the digestive tract. Appl Environ Microbiol 1999, 65:4881-4886.
    • (1999) Appl Environ Microbiol , vol.65 , pp. 4881-4886
    • Drouault, S.1    Corthier, G.2    Ehrlich, S.D.3    Renault, P.4
  • 38
    • 0034714188 scopus 로고    scopus 로고
    • Treatment of murine colitis by Lactococcus lactis secreting interleukin-10
    • Steidler L., Hans W., Schotte L., Neirynck S., Obermeier F., Falk W., et al. Treatment of murine colitis by Lactococcus lactis secreting interleukin-10. Science 2000, 289:1352-1355.
    • (2000) Science , vol.289 , pp. 1352-1355
    • Steidler, L.1    Hans, W.2    Schotte, L.3    Neirynck, S.4    Obermeier, F.5    Falk, W.6
  • 39
    • 34547503872 scopus 로고    scopus 로고
    • Induction of ovalbumin-specific tolerance by oral administration of Lactococcus lactis secreting ovalbumin
    • Huibregtse I.L., Snoeck V., de Creus A., Braat H., De Jong E.C., Van Deventer S.J., et al. Induction of ovalbumin-specific tolerance by oral administration of Lactococcus lactis secreting ovalbumin. Gastroenterology 2007, 133:517-528.
    • (2007) Gastroenterology , vol.133 , pp. 517-528
    • Huibregtse, I.L.1    Snoeck, V.2    de Creus, A.3    Braat, H.4    De Jong, E.C.5    Van Deventer, S.J.6
  • 40
    • 79956080318 scopus 로고    scopus 로고
    • Oral administration of Lactococcus lactis delivered heat shock protein 65 attenuates atherosclerosis in low-density lipoprotein receptor-deficient mice
    • Hou J., Lu Y., Liu H.Y., Ma Y.J., Xing Y., Zhang Y., et al. Oral administration of Lactococcus lactis delivered heat shock protein 65 attenuates atherosclerosis in low-density lipoprotein receptor-deficient mice. Vaccine 2011, 29:4102-4109.
    • (2011) Vaccine , vol.29 , pp. 4102-4109
    • Hou, J.1    Lu, Y.2    Liu, H.Y.3    Ma, Y.J.4    Xing, Y.5    Zhang, Y.6
  • 41
    • 43049161297 scopus 로고    scopus 로고
    • Innate inflammatory responses to the Gram-positive bacterium Lactococcus lactis
    • Yam K.K., Pouliot P., N'Diaye M.M., Fournier S., Olivier M., Cousineau B. Innate inflammatory responses to the Gram-positive bacterium Lactococcus lactis. Vaccine 2008, 26:2689-2699.
    • (2008) Vaccine , vol.26 , pp. 2689-2699
    • Yam, K.K.1    Pouliot, P.2    N'Diaye, M.M.3    Fournier, S.4    Olivier, M.5    Cousineau, B.6
  • 42
    • 0035024744 scopus 로고    scopus 로고
    • Induction of mucosal immune response after intranasal or oral inoculation of mice with Lactococcus lactis producing bovine beta-lactoglobulin
    • Chatel J.M., Langella P., Adel-Patient K., Commissaire J., Wal J.M., Corthier G. Induction of mucosal immune response after intranasal or oral inoculation of mice with Lactococcus lactis producing bovine beta-lactoglobulin. Clin Diagn Lab Immunol 2001, 8:545-551.
    • (2001) Clin Diagn Lab Immunol , vol.8 , pp. 545-551
    • Chatel, J.M.1    Langella, P.2    Adel-Patient, K.3    Commissaire, J.4    Wal, J.M.5    Corthier, G.6
  • 43
    • 79958055728 scopus 로고    scopus 로고
    • Oral immunization with live Lactococcus lactis expressing rotavirus VP8* subunit induces specific immune response in mice
    • Marelli B., Perez A.R., Banchio C., de Mendoza D., Magni C. Oral immunization with live Lactococcus lactis expressing rotavirus VP8* subunit induces specific immune response in mice. J Virol Methods 2011, 175:28-37.
    • (2011) J Virol Methods , vol.175 , pp. 28-37
    • Marelli, B.1    Perez, A.R.2    Banchio, C.3    de Mendoza, D.4    Magni, C.5
  • 44
    • 17744387781 scopus 로고    scopus 로고
    • Oral administration of recombinant Lactococcus lactis expressing bovine beta-lactoglobulin partially prevents mice from sensitization
    • Adel-Patient K., Ah-Leung S., Creminon C., Nouaille S., Chatel J.M., Langella P., et al. Oral administration of recombinant Lactococcus lactis expressing bovine beta-lactoglobulin partially prevents mice from sensitization. Clin Exp Allergy 2005, 35:539-546.
    • (2005) Clin Exp Allergy , vol.35 , pp. 539-546
    • Adel-Patient, K.1    Ah-Leung, S.2    Creminon, C.3    Nouaille, S.4    Chatel, J.M.5    Langella, P.6
  • 45
    • 84856568820 scopus 로고    scopus 로고
    • Oral immunization of mice with recombinant Lactococcus lactis expressing Cu, Zn superoxide dismutase of Brucella abortus triggers protective immunity
    • Saez D., Fernandez P., Rivera A., Andrews E., Onate A. Oral immunization of mice with recombinant Lactococcus lactis expressing Cu, Zn superoxide dismutase of Brucella abortus triggers protective immunity. Vaccine 2012, 30:1283-1290.
    • (2012) Vaccine , vol.30 , pp. 1283-1290
    • Saez, D.1    Fernandez, P.2    Rivera, A.3    Andrews, E.4    Onate, A.5
  • 47
    • 35448935267 scopus 로고    scopus 로고
    • Induction of mucosal and systemic immune responses following oral immunization of mice with Lactococcus lactis expressing human papillomavirus type 16 L1
    • Cho H.J., Shin H.J., Han I.K., Jung W.W., Kim Y.B., Sul D., et al. Induction of mucosal and systemic immune responses following oral immunization of mice with Lactococcus lactis expressing human papillomavirus type 16 L1. Vaccine 2007, 25:8049-8057.
    • (2007) Vaccine , vol.25 , pp. 8049-8057
    • Cho, H.J.1    Shin, H.J.2    Han, I.K.3    Jung, W.W.4    Kim, Y.B.5    Sul, D.6
  • 48
    • 58449109276 scopus 로고    scopus 로고
    • Structure and function of the gut mucosal immune system
    • Pabst R., Rothkotter H.J. Structure and function of the gut mucosal immune system. Adv Exp Med Biol 2006, 579:1-14.
    • (2006) Adv Exp Med Biol , vol.579 , pp. 1-14
    • Pabst, R.1    Rothkotter, H.J.2
  • 49
    • 84858598550 scopus 로고    scopus 로고
    • Mucosal co-immunization of mice with recombinant lactococci secreting VapA antigen and leptin elicits a protective immune response against Rhodococcus equi infection
    • Cauchard S., Bermudez-Humaran L.G., Blugeon S., Laugier C., Langella P., Cauchard J. Mucosal co-immunization of mice with recombinant lactococci secreting VapA antigen and leptin elicits a protective immune response against Rhodococcus equi infection. Vaccine 2011, 30:95-102.
    • (2011) Vaccine , vol.30 , pp. 95-102
    • Cauchard, S.1    Bermudez-Humaran, L.G.2    Blugeon, S.3    Laugier, C.4    Langella, P.5    Cauchard, J.6
  • 50
    • 54249133512 scopus 로고    scopus 로고
    • Oral immunization with recombinant Lactococcus lactis confers protection against respiratory pneumococcal infection
    • Villena J., Medina M., Raya R., Alvarez S. Oral immunization with recombinant Lactococcus lactis confers protection against respiratory pneumococcal infection. Can J Microbiol 2008, 54:845-853.
    • (2008) Can J Microbiol , vol.54 , pp. 845-853
    • Villena, J.1    Medina, M.2    Raya, R.3    Alvarez, S.4
  • 52
    • 0029874545 scopus 로고    scopus 로고
    • Oral immunization of interleukin-4 (IL-4) knockout mice with a recombinant Salmonella strain or cholera toxin reveals that CD4(+) Th2 cells producing IL-6 and IL-10 are associated with mucosal immunoglobulin a responses
    • Okahashi N., Yamamoto M., Vancott J.L., Chatfield S.N., Roberts M., Bluethmann H., et al. Oral immunization of interleukin-4 (IL-4) knockout mice with a recombinant Salmonella strain or cholera toxin reveals that CD4(+) Th2 cells producing IL-6 and IL-10 are associated with mucosal immunoglobulin a responses. Infect Immun 1996, 64:1516-1525.
    • (1996) Infect Immun , vol.64 , pp. 1516-1525
    • Okahashi, N.1    Yamamoto, M.2    Vancott, J.L.3    Chatfield, S.N.4    Roberts, M.5    Bluethmann, H.6
  • 53
    • 84864349515 scopus 로고    scopus 로고
    • Oral immunization with attenuated Salmonella vaccine expressing Escherichia coli O157:H7 intimin gamma triggers both systemic and mucosal humoral immunity in mice
    • Oliveira A.F., Cardoso S.A., Almeida F.B.D., de Oliveira L.L., Pitondo-Silva A., Soares S.G., et al. Oral immunization with attenuated Salmonella vaccine expressing Escherichia coli O157:H7 intimin gamma triggers both systemic and mucosal humoral immunity in mice. Microbiol Immunol 2012, 56:513-522.
    • (2012) Microbiol Immunol , vol.56 , pp. 513-522
    • Oliveira, A.F.1    Cardoso, S.A.2    Almeida, F.B.D.3    de Oliveira, L.L.4    Pitondo-Silva, A.5    Soares, S.G.6
  • 54
    • 0346881406 scopus 로고    scopus 로고
    • Plant cell-based intimin vaccine given orally to mice primed with intimin reduces time of Escherichia coli O157:H7 shedding in feces
    • Judge N.A., Mason H.S., O'Brien A.D. Plant cell-based intimin vaccine given orally to mice primed with intimin reduces time of Escherichia coli O157:H7 shedding in feces. Infect Immun 2004, 72:168-175.
    • (2004) Infect Immun , vol.72 , pp. 168-175
    • Judge, N.A.1    Mason, H.S.2    O'Brien, A.D.3
  • 55
    • 84879463772 scopus 로고    scopus 로고
    • Advances in the development of enterohemorrhagic Escherichia coli vaccines using murine models of infection
    • Garcia-Angulo V.A., Kalita A., Torres A.G. Advances in the development of enterohemorrhagic Escherichia coli vaccines using murine models of infection. Vaccine 2013, 31:3229-3235.
    • (2013) Vaccine , vol.31 , pp. 3229-3235
    • Garcia-Angulo, V.A.1    Kalita, A.2    Torres, A.G.3
  • 56
    • 44649083062 scopus 로고    scopus 로고
    • Subcutaneous and intranasal immunization with type III secreted proteins can prevent colonization and shedding of Escherichia coli O157:H7 in mice
    • Babiuk S., Asper D.J., Rogan D., Mutwiri G.K., Potter A.A. Subcutaneous and intranasal immunization with type III secreted proteins can prevent colonization and shedding of Escherichia coli O157:H7 in mice. Microb Pathog 2008, 45:7-11.
    • (2008) Microb Pathog , vol.45 , pp. 7-11
    • Babiuk, S.1    Asper, D.J.2    Rogan, D.3    Mutwiri, G.K.4    Potter, A.A.5
  • 57
    • 84860344091 scopus 로고    scopus 로고
    • Protection against Escherichia coli O157:H7 challenge by immunization of mice with purified Tir proteins
    • Fan H.Y., Wang L., Luo J., Long B.G. Protection against Escherichia coli O157:H7 challenge by immunization of mice with purified Tir proteins. Mol Biol Rep 2012, 39:989-997.
    • (2012) Mol Biol Rep , vol.39 , pp. 989-997
    • Fan, H.Y.1    Wang, L.2    Luo, J.3    Long, B.G.4
  • 58
    • 79955674080 scopus 로고    scopus 로고
    • Reduced faecal shedding of Escherichia coli O157:H7 in cattle following systemic vaccination with gamma-intimin C-280 and EspB proteins
    • Vilte D.A., Larzabal M., Garbaccio S., Gammella M., Rabinovitz B.C., Elizondo A.M., et al. Reduced faecal shedding of Escherichia coli O157:H7 in cattle following systemic vaccination with gamma-intimin C-280 and EspB proteins. Vaccine 2011, 29:3962-3968.
    • (2011) Vaccine , vol.29 , pp. 3962-3968
    • Vilte, D.A.1    Larzabal, M.2    Garbaccio, S.3    Gammella, M.4    Rabinovitz, B.C.5    Elizondo, A.M.6
  • 59
    • 79961002080 scopus 로고    scopus 로고
    • Immunization of sheep with a combination of intimin gamma, EspA and EspB decreases Escherichia coli O157:H7 shedding
    • Atefyekta M., Goddeeris B.M., Vanrompay D., Cox E. Immunization of sheep with a combination of intimin gamma, EspA and EspB decreases Escherichia coli O157:H7 shedding. Vet Immunol Immunopathol 2011, 140:42-46.
    • (2011) Vet Immunol Immunopathol , vol.140 , pp. 42-46
    • Atefyekta, M.1    Goddeeris, B.M.2    Vanrompay, D.3    Cox, E.4
  • 60
    • 84901992170 scopus 로고    scopus 로고
    • The immune system: differences between man, pigs, ruminants and mice
    • Bailey M. The immune system: differences between man, pigs, ruminants and mice. Front Immunol 2011, 10.3389/conf.fimmu.2011.01.00003.
    • (2011) Front Immunol
    • Bailey, M.1
  • 61
    • 0020600404 scopus 로고
    • Plasmid complements of Streptococcus lactis NCDO 712 and other lactic streptococci after protoplast-induced curing
    • Gasson M.J. Plasmid complements of Streptococcus lactis NCDO 712 and other lactic streptococci after protoplast-induced curing. J Bacteriol 1983, 154:1-9.
    • (1983) J Bacteriol , vol.154 , pp. 1-9
    • Gasson, M.J.1
  • 63
    • 0042427336 scopus 로고    scopus 로고
    • Non-toxigenic Escherichia coli O157:H7 strain NCTC12900 causes attaching-effacing lesions and eae-dependent persistence in weaned sheep
    • Woodward M.J., Best A., Sprigings K.A., Pearson G.R., Skuse A.M., Wales A., et al. Non-toxigenic Escherichia coli O157:H7 strain NCTC12900 causes attaching-effacing lesions and eae-dependent persistence in weaned sheep. Int J Med Microbiol 2003, 293:299-308.
    • (2003) Int J Med Microbiol , vol.293 , pp. 299-308
    • Woodward, M.J.1    Best, A.2    Sprigings, K.A.3    Pearson, G.R.4    Skuse, A.M.5    Wales, A.6
  • 64
    • 27544451339 scopus 로고    scopus 로고
    • 10 years of the nisin-controlled gene expression system (NICE) in Lactococcus lactis
    • Mierau I., Kleerebezem M. 10 years of the nisin-controlled gene expression system (NICE) in Lactococcus lactis. Appl Microbiol Biotechnol 2005, 68:705-717.
    • (2005) Appl Microbiol Biotechnol , vol.68 , pp. 705-717
    • Mierau, I.1    Kleerebezem, M.2


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