Three-dimensional analysis of molar development in the mouse from the cap to bell stage

Australian Dental Journal

Volumn 59, Issue SUPPL. 1, 2014, Pages 81-100

  Lesot, H ^a,b   Hovorakova, M ^c   Peterka, M ^c   Peterkova, R ^c  

^a Université de Strasbourg   (France)

^b UNIVERSITÉ DE STRASBOURG   (France)

^c INSTITUTE OF EXPERIMENTAL MEDICINE   (Czech Republic)

Author keywords

cytodifferentiation; histo morphogenesis; molar; mouse; Tooth development

Indexed keywords

AMELOBLAST; ANIMAL; ARTICLE; CELL DIFFERENTIATION; CYTOLOGY; EPITHELIUM; HISTO-MORPHOGENESIS; MESODERM; MOLAR TOOTH; MOUSE; ODONTOBLAST; PERIODONTAL DISEASE; PHYSIOLOGY; PRENATAL DEVELOPMENT; THREE DIMENSIONAL IMAGING; TOOTH CERVIX; TOOTH CROWN; TOOTH DEVELOPMENT;

CYTODIFFERENTIATION; HISTO-MORPHOGENESIS; MOLAR; MOUSE; TOOTH DEVELOPMENT;

AMELOBLASTS; ANIMALS; CELL DIFFERENTIATION; DENTINOGENESIS; EPITHELIUM; IMAGING, THREE-DIMENSIONAL; MESODERM; MICE; MOLAR; ODONTOBLASTS; ODONTOGENESIS; TOOTH CERVIX; TOOTH CROWN; TOOTH MIGRATION;

EID: 84902001277     PISSN: 00450421     EISSN: 18347819     Source Type: Journal    
DOI: 10.1111/adj.12132     Document Type: Article

References (136)

1. Radlanski RJ,. Morphogenesis of human tooth primordia: the importance of 3D computer-assisted reconstruction. Int J Dev Biol 1995; 39: 249-256.
2. Yamanaka A, Yasui K, Sonomura T, Uemura M,. Development of heterodont dentition in house shrew (Suncus murinus). Eur J Oral Sci 2007; 115: 433-440.
3. Buchtova M, Handrigan GR, Tucker AS, et al,. Initiation and patterning of the snake dentition are dependent on Sonic hedgehog signaling. Dev Biol 2008; 319: 132-145.
4. Handrigan GR, Leung KJ, Richman JM,. Identification of putative dental epithelial stem cells in a lizard with life-long tooth replacement. Development 2010; 137: 3545-3549.
5. Kettunen P, Løes S, Furmanek T, et al,. Coordination of trigeminal axon navigation and patterning with tooth organ formation: epithelial- mesenchymal interactions, and epithelial Wnt4 and Tgfbeta1 regulate semaphorin 3a expression in the dental mesenchyme. Development 2005; 132: 323-334. (Pubitemid 40268282)
6. Setkova J, Lesot H, Matalova E, Witter K, Matulova P, Misek I,. Proliferation and apoptosis in early molar morphogenesis-voles as models in odontogenesis. Int J Dev Biol 2006; 50: 481-489. (Pubitemid 43844797)
7. Salazar-Ciudad I, Jernvall J,. A computational model of teeth and the developmental origins of morphological variation. Nature 2010; 464: 583-586.
8. Peterkova R, Lesot H, Viriot L, Peterka M,. The supernumerary cheek tooth in tabby/EDA mice-a reminiscence of the premolar in mouse ancestors. Arch Oral Biol 2005; 50: 219-225. (Pubitemid 40252943)
9. Lazzari V, Charles C, Tafforeau P, et al,. Mosaic convergence of rodent dentitions. PLoS One 2008; 3: e3607.
10. Boyer DM, Lipman Y, St Clair E, et al. Algorithms to automatically quantify the geometric similarity of anatomical surfaces. Proc Natl Acad Sci U S A 2011; 108: 18221-18226.
11. Charles C, Hovorakova M, Ahn Y, et al,. Regulation of tooth number by fine-tuning levels of receptor-tyrosine kinase signaling. Development 2011; 138: 4063-4073.
12. Lungova V, Radlanski RJ, Tucker AS, Renz H, Misek I, Matalova E,. Tooth-bone morphogenesis during postnatal stages of mouse first molar development. J Anat 2011; 218: 699-716.
13. Prochazka J, Pantalacci S, Churava S, et al,. Patterning by heritage in mouse molar row development. Proc Natl Acad Sci U S A 2010; 107: 15497-15502.
14. Hovorakova M, Prochazka J, Lesot H, et al,. Shh expression in a rudimentary tooth offers new insights into development of the mouse incisor. J Exp Zool 2011; 316: 347-358.
15. Luukko K, Løes S, Furmanek T, Fjeld K, Kvinnsland IH, Kettunen P,. Identification of a novel putative signaling center, the tertiary enamel knot in the postnatal mouse molar tooth. Mech Dev 2003; 120: 270-276. (Pubitemid 36184622)
16. Arthur A, Shi S, Zannettino AC, Fujii N, Gronthos S, Koblar SA,. Implanted adult human dental pulp stem cells induce endogenous axon guidance. Stem Cells 2009; 27: 2229-2237.
17. Farahani RM, Simonian M, Hunter N,. Blueprint of an ancestral neurosensory organ revealed in glial networks in human dental pulp. J Comp Neurol 2011; 519: 3306-3326.
18. Farahani RM, Sarrafpour B, Simonian M, Li Q, Hunter N,. Directed glia-assisted angiogenesis in a mature neurosensory structure: pericytes mediate an adaptive response in human dental pulp that maintains blood-barrier function. J Comp Neurol 2012; 520: 3803-3826.
19. Ahmad N, Ruch JV,. Comparison of growth and cell proliferation kinetics during mouse molar odontogenesis in vivo and in vitro. Cell Tissue Kinet 1987; 20: 319-329.
20. Ruch JV,. Determinisms of odontogenesis. Revis Biol Celular 1987; 14: 1-99.
21. Jernvall J, Aberg T, Kettunen P, Keränen S, Thesleff I,. The life history of an embryonic signaling center: BMP-4 induces p21 and is associated with apoptosis in the mouse tooth enamel knot. Development 1998; 125: 161-169. (Pubitemid 28064430)
22. Bloch-Zupan A, Leveillard T, Gorry P, Fausser JL, Ruch JV,. Expression of p21(WAF1/CIP1) during mouse odontogenesis. Eur J Oral Sci 1998; 106 (Suppl 1): 104-111.
23. Viriot L, Peterkova R, Vonesch JL, Peterka M, Ruch JV, Lesot H,. Mouse molar morphogenesis revisited by three-dimensional reconstruction. III. Spatial distribution of mitoses and apoptoses up to bell-staged first lower molar teeth. Int J Dev Biol 1997; 41: 679-690. (Pubitemid 27475611)
24. Lesot H, Peterkova R, Schmitt R, et al,. Initial features of the inner dental epithelium histo-morphogenesis in the first lower molar in mouse. Int J Dev Biol 1999; 43: 245-254. (Pubitemid 29268342)
25. Lesot H, Kieffer-Combeau S, Fausser JL, et al,. Cell-cell and cell-matrix interactions during initial enamel organ histomorphogenesis in the mouse. Connect Tissue Res 2002; 43: 191-200. (Pubitemid 34777924)
26. Raymond K, Faraldo MM, Deugnier MA, Glukhova MA,. Integrins in mammary development. Semin Cell Dev Biol 2012; 23: 599-605.
27. Lu P, Takai K, Weaver VM, Werb Z,. Extracellular matrix degradation and remodelling in development and disease. Cold Spring Harb Perspect Biol 2011; 3 pii: a005058. doi: 10.1101/cshperspect.a005058.
28. Shigemura N, Kiyoshima T, Kobayashi I, et al,. The distribution of BrdU- and TUNEL-positive cells during odontogenesis in mouse lower first molars. Histochem J 1999; 31: 367-377. (Pubitemid 29362821)
29. Coin R, Lesot H, Vonesch JL, Haikel Y, Ruch JV,. Aspects of cell proliferation kinetics of the inner dental epithelium during mouse molar and incisor morphogenesis: a reappraisal of the role of the enamel knot area. Int J Dev Biol 1999; 43: 261-267. (Pubitemid 29268344)
30. Coin R, Kieffer S, Lesot H, Vonesch JL, Ruch JV,. Inhibition of apoptosis in the primary enamel knot does not affect specific tooth crown morphogenesis in the mouse. Int J Dev Biol 2000; 44: 389-396. (Pubitemid 30624793)
31. Coin R, Schmitt R, Lesot H, Vonesch JL, Ruch JV,. Regeneration of halved embryonic lower first mouse molars: correlation with the distribution pattern of non dividing IDE cells, the putative organizers of morphogenetic units, the cusps. Int J Dev Biol 2000; 44: 289-295. (Pubitemid 30368072)
32. Obara N, Lesot H,. Asymmetrical growth, differential cell proliferation, and dynamic cell rearrangement underlie epithelial morphogenesis in mouse molar development. Cell Tissue Res 2007; 330: 461-473. (Pubitemid 350098215)
33. Lisi S, Peterkova R, Peterka M, Vonesch JL, Ruch JV, Lesot H,. Tooth morphogenesis and pattern of odontoblast differentiation. Connect Tissue Res 2003; 44 (Suppl 1): 167-170. (Pubitemid 36395440)
34. Kollar EJ, Baird GR,. The influence of the dental papilla on the development of tooth shape in embryonic mouse tooth germs. J Embryol Exp Morphol 1969; 21: 131-148.
35. Kollar EJ, Baird GR,. Tissue interactions in embryonic mouse tooth germs. II. The inductive role of the dental papilla. J Embryol Exp Morphol 1970; 24: 173-186.
36. Schmitt R, Lesot H, Vonesch JL, Ruch JV,. Mouse odontogenesis in vitro: the cap-stage mesenchyme controls individual molar crown morphogenesis. Int J Dev Biol 1999; 43: 255-260. (Pubitemid 29268343)
37. Nait Lechguer A, Kuchler-Bopp S, Lesot H,. Crown formation during tooth development and tissue engineering. J Exp Zool 2009; 312B: 399-407.
38. Yoshiba K, Yoshiba N, Aberdam D, et al,. Expression and localization of laminin-5 subunits during mouse tooth development. Dev Dyn 1998; 211: 164-176. (Pubitemid 28080135)
39. Yoshiba K, Yoshiba N, Aberdam D, et al,. Differential expression of laminin-5 subunits during incisor and molar development in the mouse. Int J Dev Biol 2000; 44: 337-340. (Pubitemid 30368079)
40. Udayakumar TS, Chen ML, Bair EL, et al,. Membrane type-1-matrix metalloproteinase expressed by prostate carcinoma cells cleaves human laminin-5 beta3 chain and induces cell migration. Cancer Res 2003; 63: 2292-2299. (Pubitemid 36538639)
41. Hintermann E, Quaranta V,. Epithelial cell motility on laminin-5: regulation by matrix assembly, proteolysis, integrins and erbB receptors. Matrix Biol 2004; 23: 75-85. (Pubitemid 38891522)
42. Fata JE, Leco KJ, Moorehead RA, Martin DC, Khokha R,. Timp-1 is important for epithelial proliferation and branching morphogenesis during mouse mammary development. Dev Biol 1999; 211: 238-254. (Pubitemid 29343279)
43. Koshikawa N, Giannelli G, Cirulli V, Miyazaki K, Quaranta V,. Role of cell surface metalloprotease MT1-MMP in epithelial cell migration over laminin-5. J Cell Biol 2000; 148: 615-624.
44. Yoshiba N, Yoshiba K, Stoetzel C, et al,. Temporospatial gene expression and protein localization of matrix metalloproteinases and their inhibitors during mouse molar tooth development. Dev Dyn 2003; 228: 105-112. (Pubitemid 37064848)
45. Meyer JM, Ruch JV, Kubler MD, Kupferle C, Lesot H,. Cultured incisors display major modifications in basal lamina deposition without further effect on odontoblast differentiation. Cell Tissue Res 1995; 279: 135-147.
46. Hu CC, Sakakura Y, Sasano Y, et al,. Endogenous epidermal growth factor regulates the timing and pattern of embryonic mouse molar tooth morphogenesis. Int J Dev Biol 1992; 36: 505-516. (Pubitemid 23051872)
47. Mark MP, Bloch-Zupan A, Ruch JV,. Effects of retinoids on tooth morphogenesis and cytodifferentiations, in vitro. Int J Dev Biol 1992; 36: 517-526. (Pubitemid 23051873)
48. Sato E, Kameyama Y, Maeda H, Fujita K, Takesue M,. Retardation of mouse odontoblast differentiation by heparin in vitro. Arch Oral Biol 1993; 38: 145-150. (Pubitemid 223068768)
49. Nait Lechguer A, Kuchler-Bopp S, Hu B, Haïkel Y, Lesot H,. Vascularization of engineered teeth. J Dent Res 2008; 87: 1138-1143.
50. Rothova M, Feng J, Sharpe PT, Peterkova R, Tucker AS,. Contribution of mesoderm to the developing dental papilla. Int J Dev Biol 2011; 55: 59-64.
51. Luukko K, Kvinnsland IH, Kettunen P,. Tissue interactions in the regulation of axon pathfinding during tooth morphogenesis. Dev Dyn 2005; 234: 482-488. (Pubitemid 41532970)
52. Moe K, Kettunen P, Kvinnsland IH, Luukko K,. Development of the pioneer sympathetic innervation into the dental pulp of the mouse mandibular first molar. Arch Oral Biol 2008; 53: 865-873.
53. Keller L, Kuchler-Bopp S, Mendoza SA, Poliard A, Lesot H,. Restoring the physiological cell heterogeneity in the mesenchyme during tooth engineering. Int J Dev Biol 2012; 56: 737-746.
54. Chai Y, Jiang X, Ito Y, et al,. Fate of the mammalian cranial neural crest during tooth and mandibular morphogenesis. Development 2000; 127: 1671-1679. (Pubitemid 30234924)
55. Gamer LW, Nove J, Rosen V,. Return of the chalones. Dev Cell 2003; 4: 143-144.
56. Hata RI,. Where am I? How a cell recognizes its positional information during morphogenesis. Cell Biol Int 1996; 20: 59-65.
57. Nievergall E, Lackmann M, Janes PW,. Eph-dependent cell-cell adhesion and segregation in development and cancer. Cell Mol Life Sci 2012; 69: 1813-1842.
58. Lesot H, Brook AH,. Epithelial histogenesis during tooth development. Arch Oral Biol 2009; 54 (Suppl 1): S25-S33.
59. Nadiri A, Kuchler-Bopp S, Haikel Y, Lesot H,. Immunolocalization of BMP-2/-4, FGF-4, and WNT10b in the developing mouse first lower molar. J Histochem Cytochem 2004; 52: 103-112. (Pubitemid 38032137)
60. Meyer JM, Steuer P, Obara N, Vonesch JL, Lesot H,. Histogenesis of the inner dental epithelium during molar development in the mouse. In:, Zadzinska E, ed. Current Trends in Dental Morphology Research. Lodz: University of Lodz Press, 2005: 411-419.
61. Jarov A, Williams KP, Ling LE, Koteliansky VE, Duband JL, Fournier-Thibault C,. A dual role for Sonic hedgehog in regulating adhesion and differentiation of neuroepithelial cells. Dev Biol 2003; 261: 520-536. (Pubitemid 37108790)
62. Fan H, Oro AE, Scott MP, Khavari PA,. Induction of basal cell carcinoma features in transgenic human skin expressing Sonic Hedgehog. Nat Med 1997; 3: 788-792.
63. Obara N, Suzuki Y, Nagai Y, Takeda M,. Expression of E- and P-cadherin during tooth morphogenesis and cytodifferentiation of ameloblasts. Anat Embryol (Berl) 1998; 197: 469-475. (Pubitemid 28287058)
64. Lesot H, Lisi S, Peterkova R, Peterka M, Mitolo V, Ruch JV,. Epigenetic signals during odontoblast differentiation. Adv Dent Res 2001; 15: 8-13.
65. Day SJ, Lawrence PA,. Measuring dimensions: the regulation of size and shape. Development 2000; 127: 2977-2987. (Pubitemid 30611891)
66. Risnes S,. Growth tracks in dental enamel. J Hum Evol 1998; 35: 331-350. (Pubitemid 29109841)
67. Tabata MJ, Kim K, Liu JG, et al,. Hepatocyte growth factor is involved in the morphogenesis of tooth germ in murine molars. Development 1996; 122: 1243-1251. (Pubitemid 26123899)
68. Nanci A, Mocetti P, Sakamoto Y, Kunikata M, Lozupone E, Bonucci E,. Morphological and immunocytochemical analyses on the effects of diet-induced hypocalcemia on enamel maturation in the rat incisor. J Histochem Cytochem 2000; 48: 1043-1058.
69. Fausser JL, Schlepp O, Aberdam D, Meneguzzi G, Ruch JV, Lesot H,. Localization of antigens associated with adherens junctions, desmosomes, and hemidesmosomes during murine molar morphogenesis. Differentiation 1998; 63: 1-11. (Pubitemid 28221273)
70. Nakamura H, Ozawa H,. Immunolocalization of CD44 and the ezrin-radixin-moesin (ERM) family in the stratum intermedium and papillary layer of the mouse enamel organ. J Histochem Cytochem 1997; 45: 1481-1492. (Pubitemid 27465469)
71. Yoshida T, Miyoshi J, Takai Y, Thesleff I,. Cooperation of nectin-1 and nectin-3 is required for normal ameloblast function and crown shape development in mouse teeth. Dev Dyn 2010; 239: 2558-2569.
72. Ruch JV, Lesot H, Karcher-Djuricic V, Meyer JM, Olive M,. Facts and hypotheses concerning the control of odontoblast differentiation. Differentiation 1982; 21: 7-12. (Pubitemid 12129764)
73. Linde A, Goldberg M,. Dentinogenesis. Crit Rev Oral Biol Med 1993; 4: 679-728. (Pubitemid 24005050)
74. Butler WT,. Dentine matrix proteins. Eur J Oral Sci 1998; 106 (Suppl 1): 204-210.
75. Smith AJ, Lesot H,. Induction and regulation of crown dentinogenesis: embryonic events as a template for dental tissue repair? Crit Rev Oral Biol Med 2001; 12: 425-437. (Pubitemid 33022038)
76. Ruch JV,. Odontoblast commitment and differentiation. Biochem Cell Biol 1998; 76: 923-938. (Pubitemid 29450561)
77. Magloire H, Couble ML, Romeas A, Bleicher F,. Odontoblast primary cilia: facts and hypotheses. Cell Biol Int 2004; 28: 93-99. (Pubitemid 38258235)
78. Allard B, Magloire H, Couble ML, Maurin JC, Bleicher F,. Voltage-gated sodium channels confer excitability to human odontoblasts: possible role in tooth pain transmission. J Biol Chem 2006; 281: 29002-29010. (Pubitemid 44507044)
79. Ibuki T, Kido MA, Kiyoshima T, Terada Y, Tanaka T,. An ultrastructural study of the relationship between sensory trigeminal nerves and odontoblasts in rat dentine/pulp as demonstrated by the anterograde transport of wheat germ agglutinin-horseradish peroxidase (WGA-HRP). J Dent Res 1996; 75: 1963-1970. (Pubitemid 32770438)
80. Magloire H, Allard B, Couble ML, Maurin JC, Bleicher F,. Mechanosensitive ion channels in odontoblasts. In:, Kamkin A, Kiseleva I, eds. Mechanosensitivity in cells and tissues: mechanosensitive ion channels. Springer, 2008: 147-155.
81. Ruch JV, Lesot H, Begue-Kirn C,. Odontoblast differentiation. Int J Dev Biol 1995; 39: 51-68.
82. Ruch JV,. Patterned distribution of differentiating dental cells: facts and hypotheses. J Biol Buccale 1990; 18: 91-98.
83. Jernvall J, Thesleff I,. Reiterative signaling and patterning during mammalian tooth morphogenesis. Mech Dev 2000; 92: 19-29. (Pubitemid 30125959)
84. Deutsch D,. Structure and function of enamel gene products. Anat Rec 1989; 224: 189-210. (Pubitemid 19184418)
85. Nanci A, Smith CE,. Development and calcification of enamel. In:, Bonucci E, ed. Calcification in biological systems. Boca Raton: CRC Press, 1992: 313-343.
86. Wang H, Tannukit S, Zhu D, Snead ML, Paine ML,. Enamel matrix protein interactions. J Bone Miner Res 2005; 20: 1032-1040. (Pubitemid 40712828)
87. Simmer JP, Papagerakis P, Smith CE, et al,. Regulation of dental enamel shape and hardness. J Dent Res 2010; 89: 1024-1038.
88. Bawden JW,. Calcium transport during mineralization. Anat Rec 1989; 224: 226-233. (Pubitemid 19184421)
89. Takano Y, Crenshaw MA, Bawden JW,. Calcium movement in vivo and in vitro in secretory-stage enamel of rat incisors. Arch Oral Biol 1992; 37: 377-383.
90. Hubbard MJ,. Calcium transport across the dental enamel epithelium. Crit Rev Oral Biol Med 2000; 11: 437-466. (Pubitemid 32003256)
91. Warshawsky H, Josephsen K, Thylstrup A, Fejerskov O,. The development of enamel structure in rat incisors as compared to the teeth of monkey and man. Anat Rec 1981; 200: 371-399. (Pubitemid 11044358)
92. Joseph BK, Harbrow DJ, Sugerman PB, Smid JR, Savage NW, Young WG,. Ameloblast apoptosis and IGF-1 receptor expression in the continuously erupting rat incisor model. Apoptosis 1999; 4: 441-447.
93. Tsuchiya M, Sharma R, Tye CE, Sugiyama T, Bartlett JD,. Transforming growth factor-beta1 expression is up-regulated in maturation-stage enamel organ and may induce ameloblast apoptosis. Eur J Oral Sci 2009; 117: 105-112.
94. Karcher-Djuricic V, Staubli A, Meyer JM, Ruch JV,. Acellular dental matrices promote functional differentiation of ameloblasts. Differentiation 1985; 29: 169-175. (Pubitemid 15045651)
95. Zeichner-David M, Diekwisch T, Fincham A, et al,. Control of ameloblast differentiation. Int J Dev Biol 1995; 39: 69-92.
96. Gaunt WA,. The development of enamel and dentine on the molars of the mouse, with an account of the enamel-free areas. Acta Anat (Basel) 1956; 28: 111-134.
97. Nait Lechguer A, Couble ML, Labert N, et al,. Cell differentiation and matrix organization in engineered teeth. J Dent Res 2011; 90: 583-589.
98. Kawano S, Saito M, Handa K, et al,. Characterization of dental epithelial progenitor cells derived from cervical-loop epithelium in a rat lower incisor. J Dent Res 2004; 83: 129-133. (Pubitemid 41713796)
99. Harada H, Ichimori Y, Yokohama-Tamaki T, et al,. Stratum intermedium lineage diverges from ameloblast lineage via Notch signaling. Biochem Biophys Res Commun 2006; 340: 611-616. (Pubitemid 43021790)
100. Matthiessen ME, Rømert P,. Ultrastructure of the human enamel organ. I. External enamel epithelium, stellate reticulum, and stratum intermedium. Cell Tissue Res 1980; 205: 361-370. (Pubitemid 10152866)
101. Kallenbach E,. Fine structure of the stratum intermedium, stellate reticulum, and outer enamel epithelium in the enamel organ of the kitten. J Anat 1978; 126: 247-260. (Pubitemid 8363786)
102. Wakita M, Hinrichsen K,. Ultrastructure of the ameloblast-stratum intermedium border during ameloblast differentiation. Acta Anat (Basel) 1980; 108: 10-29. (Pubitemid 10073458)
103. Ohazama A, Sharpe PT,. Expression of claudins in murine tooth development. Dev Dyn 2007; 236: 290-294. (Pubitemid 46095100)
104. Smith CE, Nanci A,. Overview of morphological changes in enamel organ cells associated with major events in amelogenesis. Int J Dev Biol 1995; 39: 153-161.
105. Deporter DA, Ten Cate AR,. Fine structural localization of alkaline phosphatase in relation to enamel formation in the mouse molar. Arch Oral Biol 1976; 21: 7-12.
106. Sasaki T, Segawa K, Takiguchi R, Higashi S,. Intercellular junctions in the cells of the human enamel organ as revealed by freeze-fracture. Arch Oral Biol 1984; 29: 275-286.
107. Taylor AN, Gleason WA Jr, Lankford GL,. Immunocytochemical localization of rat intestinal vitamin D-dependent calcium-binding protein. J Histochem Cytochem 1984; 32: 153-158. (Pubitemid 14184306)
108. Nakamura H, Ozawa H,. Lectin cytochemistry on the stratum intermedium and the papillary layer in the rat incisor enamel organ. Arch Histol Cytol 1990; 53: 351-369. (Pubitemid 20346014)
109. Satokata I, Ma L, Ohshima H, et al,. Msx2 deficiency in mice causes pleiotropic defects in bone growth and ectodermal organ formation. Nat Genet 2000; 24: 391-395. (Pubitemid 30187439)
110. Bei M, Stowell S, Maas R,. Msx2 controls ameloblast terminal differentiation. Dev Dyn 2004; 231: 758-765. (Pubitemid 40022737)
111. Gritli-Linde A, Bei M, Maas R, Zhang XM, Linde A, McMahon AP,. Shh signaling within the dental epithelium is necessary for cell proliferation, growth and polarization. Development 2002; 129: 5323-5337. (Pubitemid 36040329)
112. Løes S, Luukko K, Kvinnsland IH, Kettunen P,. Slit1 is specifically expressed in the primary and secondary enamel knots during molar tooth cusp formation. Mech Dev 2001; 107: 155-157. (Pubitemid 32755813)
113. Sakakura Y, Fujiwara N, Nawa T,. Epithelial cytodifferentiation and extracellular matrix formation in enamel-free areas of the occlusal cusp during development of mouse molars: light and electron microscopic studies. Am J Anat 1989; 184: 287-297. (Pubitemid 19153154)
114. Diab MM, Zaki AE,. Morphology and cytidine-5'-monophosphatase cytochemistry of odontogenic epithelium at the enamel-free areas of mouse molars. Arch Oral Biol 1991; 36: 361-370.
115. Inai T, Nagata K, Kukita T, Kurisu K,. Demonstration of amelogenin in the enamel-free cusps of rat molar tooth germs: immunofluorescent and immunoelectron microscopic studies. Anat Rec 1992; 233: 588-596.
116. Hawkinson RW, Eisenmann DR,. Electron microscopy of dentinal tubule sclerosis in the enamel-free region of the rat molar. Arch Oral Biol 1983; 28: 409-414.
117. Barrows MJ, Ashrafi SH, Weber DF,. Microradiographic and electron microscopic observations of the enamel-covered dentine in rat molars. Arch Oral Biol 1984; 29: 461-466.
118. Sutcliffe JE, Owens PD,. Microscopy of resorption of enamel and dentine from the cusp tips of the molar teeth of rats. Arch Oral Biol 1981; 26: 29-39. (Pubitemid 11185032)
119. Bosshardt DD, Nanci A,. Immunolocalization of epithelial and mesenchymal matrix constituents in association with inner enamel epithelial cells. J Histochem Cytochem 1998; 46: 135-142. (Pubitemid 28087843)
120. Wurtz T, Lundmark C, Christersson C, Bawden JW, Slaby I, Hammarström L,. Expression of amelogenin mRNA sequences during development of rat molars. J Bone Miner Res 1996; 11: 125-131. (Pubitemid 26026752)
121. Bosshardt DD, Nanci A,. Immunodetection of enamel- and cementum-related (bone) proteins at the enamel-free area and cervical portion of the tooth in rat molars. J Bone Miner Res 1997; 12: 367-379. (Pubitemid 27120473)
122. Gaunt WA,. Changes in the form of the jaws of the albino mouse during ontogeny. Acta Anat (Basel) 1964; 58: 37-61.
123. Jelínek R, Peterka M,. The role of the mandible in mouse palatal development revisited. Cleft Palate J 1977; 14: 211-221. (Pubitemid 8161128)
124. Peterka M, Vonesch JL, Ruch JV, Cam Y, Peterkova R, Lesot H,. Position and growth of upper and lower tooth primordia in prenatal mouse-3D study. J Craniofac Genet Dev Biol 2000; 20: 35-43. (Pubitemid 30311843)
125. Kieffer S, Peterkova R, Vonesch JL, Ruch JV, Peterka M, Lesot H,. Morphogenesis of the lower incisor in the mouse from the bud to early bell stage. Int J Dev Biol 1999; 43: 531-539.
126. Lesot H, Kristenova P, Haze A, Deutsch D, Peterka M, Peterkova R,. Lower incisor in the Tabby mutant mouse. In:, Landis WL, Sodek J, eds. Proceedings of the 8th Conference on Chemistry and Biology of Mineralized Tissues 2004: 196-199.
127. Diewert VM,. Graphic reconstructions of craniofacial structures during secondary palate development in rats. Teratology 1976; 14: 291-313. (Pubitemid 8004924)
128. Cam Y, Fausser JL, Vonesch JL, et al,. Asymmetrical morphogenesis and medio-lateral positioning of molars during mouse development. Eur J Oral Sci 2002; 110: 35-43.
129. Peterkova R, Peterka M, Viriot L, Lesot H,. Dentition development and budding morphogenesis. J Craniofac Genet Dev Biol 2000; 20: 158-172. (Pubitemid 32336895)
130. Jernvall J, Kettunen P, Karavanova I, Martin LB, Thesleff I,. Evidence for the role of the enamel knot as a control center in mammalian tooth cusp formation: non-dividing cells express growth stimulating Fgf-4 gene. Int J Dev Biol 1994; 38: 463-469. (Pubitemid 24334077)
131. Ohazama A, Courtney JM, Tucker AS,. Traf6 is essential for murine tooth cusp morphogenesis. Dev Dyn 2004; 229: 131-135. (Pubitemid 38036828)
132. Wang XP, Suomalainen M, Jorgez CJ, et al,. Modulation of activin/bone morphogenetic protein signaling by follistatin is required for the morphogenesis of mouse molar teeth. Dev Dyn 2004; 231: 98-108. (Pubitemid 39095200)
133. Kassai Y, Munne P, Hotta Y, et al,. Regulation of mammalian tooth cusp patterning by ectodin. Science 2005; 309: 2067-2070. (Pubitemid 41362327)
134. Michon F, Tummers M, Kyyrönen M, Frilander MJ, Thesleff I,. Tooth morphogenesis and ameloblast differentiation are regulated by micro-RNAs. Dev Biol 2010; 340: 355-368.
135. Harjunmaa E, Kallonen A, Voutilainen M, Hämäläinen K, Mikkola ML, Jernvall J,. On the difficulty of increasing dental complexity. Nature 2012; 483: 324-327.
136. Thesleff I,. Current understanding of the process of tooth formation: transfer from the laboratory to the clinic. Aust Dent J 2013; doi: 10.1111/adj.12102 [Epub ahead of print].