Cross-reactive potential of human T-lymphocyte responses in HIV-1 infection

Vaccine

Volumn 32, Issue 31, 2014, Pages 3995-4000

  Giorgi, Elena E ^a   Balachandran, Harikrishnan ^b   Muldoon, Mark ^c   Letvin, Norman L ^b   Haynes, Barton F ^d   Korber, Bette T ^a,e   Santra, Sampa ^b  

^a LOS ALAMOS NATIONAL LABORATORY   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

^d DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e SANTA FE INSTITUTE   (United States)

Author keywords

Cross clade response; HIV 1; T lymphocyte

Indexed keywords

HUMAN IMMUNODEFICIENCY VIRUS VACCINE; EPITOPE; GAG PROTEIN;

ANTIGEN RECOGNITION; ARTICLE; CD4 LYMPHOCYTE COUNT; CELLULAR IMMUNITY; COHORT ANALYSIS; CONTROLLED STUDY; CROSS REACTION; ENZYME LINKED IMMUNOSPOT ASSAY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; T LYMPHOCYTE; VIRUS LOAD; CLASSIFICATION; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOLOGY;

CROSS REACTIONS; EPITOPES, T-LYMPHOCYTE; GAG GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; HIV INFECTIONS; HIV-1; HUMANS; T-LYMPHOCYTES;

EID: 84901986802     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2014.04.040     Document Type: Article

References (16)

1. Geldmacher C., Currier J.R., Gerhardt M., Haule A., Maboko L., Birx D., Gray C., Meyerhans A., Cox J., Hoelscher M. In a mixed subtype epidemic, the HIV-1 Gag-specific T-lymphocyte response is biased towards the infecting subtype. AIDS 2007, 21:135-143.
2. Santra S., Korber B.T., Muldoon M., Barouch D.H., Nabel G.J., Gao F., Hahn B.H., Haynes B.F., Letvin N.L. A centralized gene-based HIV-1 vaccine elicits broad cross-clade cellular immune responses in rhesus monkeys. Proc Nat Acad Sci USA 2008, 105:10489-10494.
3. Santra S., Liao H.X., Zhang R., Muldoon M., Watson S., Fischer W., Theiler J., Szinger J., Balachandran H., Buzby A., Quinn D., Parks R.J., Tsao C.Y., Carville A., Mansfield K.G., Pavlakis G.N., Felber B.K., Haynes B.F., Korber B.T., Letvin N.L. Mosaic vaccines elicit CD8+ T lymphocyte responses that confer enhanced immune coverage of diverse HIV strains in monkeys. Nat Med 2010, 16:324-328.
4. Gaschen B., Taylor J., Yusim K., Foley B., Gao F., Lang D., Novitsky V., Haynes B., Hahn B.H., Bhattacharya T., Korber B. Diversity considerations in HIV-1 vaccine selection. Science 2002, 296:2354-2360.
5. Li F., Malhotra U., Gilbert P.B., Hawkins N.R., Duerr A.C., McElrath J.M., Corey L., Self S.G. Peptide selection for human immunodeficiency virus type 1 CTL-based vaccine evaluation. Vaccine 2006, 24:6893-6904.
6. Parrish N.F., Gao F., Li H., Giorgi E.E., Barbian H.J., Parrish E.H., Zajic L., Iyer S.S., Decker J.M., Kumar A., Hora B., Berg A., Cai F., Hopper J., Denny T.N., Ding H., Ochsenbauer C., Kappes J.C., Galimidi R.P., West A.P., Bjorkman P.J., Wilen C.B., Doms R.W., O'Brien M., Bhardwaj N., Borrow P., Haynes B.F., Muldoon M., Theiler J.P., Korber B., Shaw G.M., Hahn B.H. Phenotypic properties of transmitted founder HIV-1. Proc Nat Acad Sci USA 2013, 110:6626-6633.
7. Chambers J.M., Hastie T.J. Statistical models in S 1992, Wadsworth & Brooks/Cole, Pacific Grove, CA.
8. Santra S., Muldoon M., Watson S., Buzby A., Balachandran H., Carlson K.R., Mach L., Kong W.P., McKee K., Yang Z.Y., Rao S.S., Mascola J.R., Nabel G.J., Korber B.T., Letvin N.L. Breadth of cellular and humoral immune responses elicited in rhesus monkeys by multi-valent mosaic and consensus immunogens. Virology 2012, 428:121-127.
9. Riou C., Ganusov V.V., Campion S., Mlotshwa M., Liu M.K.P., Whale V.E., Goonetilleke N., Borrow P., Ferrari G., Betts M.R., Haynes B.F., McMichael A.J., Gray C.M. Distinct kinetics of Gag-specific CD4+ and CD8+ T cell responses during acute HIV-1 infection. J Immunol 2012, 188:2198-2206.
10. Altfeld M., Lunzen J.V., Frahm N., Yu X.G., Schneider C., Eldridge R.L., Feeney M.E., Meyer-Olson D., Stellbrink H.-J., Walker B.D. Expansion of pre-existing, lymph node-localized CD8+ T cells during supervised treatment interruptions in chronic HIV infection. J Clin Invest 2002, 109:837-843.
11. Bennett M.S., Ng H.L., Ali A., Yang O.O. Cross-clade detection of HIV-1-specific cytotoxic T lymphocytes does not reflect cross-clade antiviral activity. J Infect Dis 2008, 197:390-397.
12. Altfeld M., Addo M.M., Shankarappa R., Lee P.K., Allen T.M., Yu X.G., Rathod A., Harlow J., O'Sullivan K., Johnston M.N., Goulder P.J., Mullins J.I., Rosenberg E.S., Brander C., Korber B., Walker B.D. Enhanced detection of human immunodeficiency virus type 1-specific T-lymphocyte responses to highly variable regions by using peptides based on autologous virus sequences. J Virol 2003, 77:7330-7340.
13. Malhotra U., Nolin J., Mullins J.I., McElrath M.J. Comprehensive epitope analysis of cross-clade Gag-specific T-lymphocyte responses in individuals with early HIV-1 infection in the US epidemic. Vaccine 2007, 25:381-390.
14. Barugahare B., Baker C., K'Aluoch O., Donovan R., Elrefaei M., Eggena M., Jones N., Mutalya S., Kityo C., Mugyenyi P., Cao H. Human immunodeficiency virus-specific responses in adult Ugandans: patterns of cross-clade recognition. J Virol 2005, 79:4132-4139.
15. Cao H., Kanki P., Sankalé J.L., Dieng-Sarr A., Mazzara G.P., Kalams S.A., Korber B., Mboup S., Walker B.D. Cytotoxic T-lymphocyte crossreactivity among different human immunodeficiency virus type 1 clades: implications for vaccine development. J Virol 1997, 71:8615-8623.
16. Valentine L.E., Piaskowski S.M., Rakasz E.G., Henry N.L., Wilson N.A., Watkins D.I. Recognition of escape variants in ELISPOT does not always predict CD8+ T-lymphocyte recognition of simian immunodeficiency virus-infected cells expressing the same variant sequences. J Virol 2008, 82:575-581.