-
1
-
-
60849106348
-
Ethical and scientific implications of the globalization of clinical research
-
Glickman SW, McHutchison JG, Peterson ED, Cairns CB, Harrington RA, Califf RM, Schulman KA,. Ethical and scientific implications of the globalization of clinical research. N Engl J Med 2009; 360: 816-823.
-
(2009)
N Engl J Med
, vol.360
, pp. 816-823
-
-
Glickman, S.W.1
McHutchison, J.G.2
Peterson, E.D.3
Cairns, C.B.4
Harrington, R.A.5
Califf, R.M.6
Schulman, K.A.7
-
2
-
-
84866313472
-
Implications of geographical variation on clinical outcomes of cardiovascular trials
-
Mentz RJ, Kaski JC, Dan GA, Goldstein S, Stockbridge N, Alonso-Garcia A, Ruilope LM, Martinez FA, Zannad F, Pitt B, Fiuzat M, O'Connor CM,. Implications of geographical variation on clinical outcomes of cardiovascular trials. Am Heart J 2012; 164: 303-312.
-
(2012)
Am Heart J
, vol.164
, pp. 303-312
-
-
Mentz, R.J.1
Kaski, J.C.2
Dan, G.A.3
Goldstein, S.4
Stockbridge, N.5
Alonso-Garcia, A.6
Ruilope, L.M.7
Martinez, F.A.8
Zannad, F.9
Pitt, B.10
Fiuzat, M.11
O'Connor, C.M.12
-
3
-
-
84873095762
-
Relationship between clinical trial site enrollment with participant characteristics, protocol completion, and outcomes: Insights from the EVEREST (Efficacy of Vasopressin Antagonism in Heart Failure: Outcome Study with Tolvaptan) Trial
-
Butler J, Subacius H, Vaduganathan M, Fonarow GC, Ambrosy AP, Konstam MA, Maggioni A, Mentz RJ, Swedberg K, Zannad F, Gheorghiade M,. Relationship between clinical trial site enrollment with participant characteristics, protocol completion, and outcomes: insights from the EVEREST (Efficacy of Vasopressin Antagonism in Heart Failure: Outcome Study with Tolvaptan) Trial. J Am Coll Cardiol 2013; 61: 571-579.
-
(2013)
J Am Coll Cardiol
, vol.61
, pp. 571-579
-
-
Butler, J.1
Subacius, H.2
Vaduganathan, M.3
Fonarow, G.C.4
Ambrosy, A.P.5
Konstam, M.A.6
Maggioni, A.7
Mentz, R.J.8
Swedberg, K.9
Zannad, F.10
Gheorghiade, M.11
-
4
-
-
79955766404
-
Explaining the unexpected: Insights from the PLATelet inhibition and clinical Outcomes (PLATO) trial comparing ticagrelor and clopidogrel. Editorial on Serebruany 'Viewpoint: Paradoxical excess mortality in the PLATO trial should be independently verified' (Thromb Haemost 2011; 105.5)
-
Ohman EM, Roe MT,. Explaining the unexpected: insights from the PLATelet inhibition and clinical Outcomes (PLATO) trial comparing ticagrelor and clopidogrel. Editorial on Serebruany 'Viewpoint: paradoxical excess mortality in the PLATO trial should be independently verified' (Thromb Haemost 2011; 105.5). Thromb Haemost 2011; 105: 763-765.
-
(2011)
Thromb Haemost
, vol.105
, pp. 763-765
-
-
Ohman, E.M.1
Roe, M.T.2
-
5
-
-
0030853952
-
A randomized controlled trial of epoprostenol therapy for severe congestive heart failure: The Flolan International Randomized Survival Trial (FIRST)
-
DOI 10.1016/S0002-8703(97)70105-4
-
Califf RM, Adams KF, McKenna WJ, Gheorghiade M, Uretsky BF, McNulty SE, Darius H, Schulman K, Zannad F, Handberg-Thurmond E, Harrell FE Jr, Wheeler W, Soler-Soler J, Swedberg K,. A randomized controlled trial of epoprostenol therapy for severe congestive heart failure: the Flolan International Randomized Survival Trial (FIRST). Am Heart J 1997; 134: 44-54. (Pubitemid 27329022)
-
(1997)
American Heart Journal
, vol.134
, Issue.1
, pp. 44-54
-
-
Califf, R.M.1
Adams, K.F.2
McKenna, W.J.3
Gheorghiade, M.4
Uretsky, B.F.5
McNulty, S.E.6
Darius, H.7
Schulman, K.8
Zannad, F.9
Handberg-Thurmond, E.10
Harrell Jr., F.E.11
Wheeler, W.12
Soler-Soler, J.13
Swedberg, K.14
-
6
-
-
0031747401
-
Regional differences in the characteristics and treatment of patients participating in an international heart failure trial
-
DOI 10.1016/S1071-9164(98)90502-4
-
Massie BM, Cleland JG, Armstrong PW, Horowitz JD, Packer M, Poole-Wilson PA, Ryden L,. Regional differences in the characteristics and treatment of patients participating in an international heart failure trial. The Assessment of Treatment with Lisinopril and Survival (ATLAS) Trial Investigators. J Card Fail 1998; 4: 3-8. (Pubitemid 28252535)
-
(1998)
Journal of Cardiac Failure
, vol.4
, Issue.1
, pp. 3-8
-
-
Massie, B.M.1
Cleland, J.G.F.2
Armstrong, P.W.3
Packer, M.4
Poole-Wilson, P.A.5
Lars, R.6
-
7
-
-
55049127403
-
Continental differences in clinical characteristics, management, and outcomes in patients hospitalized with worsening heart failure results from the EVEREST (Efficacy of Vasopressin Antagonism in Heart Failure: Outcome Study with Tolvaptan) program
-
Blair JE, Zannad F, Konstam MA, Cook T, Traver B, Burnett JC Jr, Grinfeld L, Krasa H, Maggioni AP, Orlandi C, Swedberg K, Udelson JE, Zimmer C, Gheorghiade M,. Continental differences in clinical characteristics, management, and outcomes in patients hospitalized with worsening heart failure results from the EVEREST (Efficacy of Vasopressin Antagonism in Heart Failure: Outcome Study with Tolvaptan) program. J Am Coll Cardiol 2008; 52: 1640-1648.
-
(2008)
J Am Coll Cardiol
, vol.52
, pp. 1640-1648
-
-
Blair, J.E.1
Zannad, F.2
Konstam, M.A.3
Cook, T.4
Traver, B.5
Burnett, Jr.J.C.6
Grinfeld, L.7
Krasa, H.8
Maggioni, A.P.9
Orlandi, C.10
Swedberg, K.11
Udelson, J.E.12
Zimmer, C.13
Gheorghiade, M.14
-
8
-
-
77956614599
-
Transatlantic similarities and differences in major natural history endpoints of heart failure after acute myocardial infarction: A propensity-matched study of the EPHESUS trial
-
Pitt B, Zannad F, Gheorghiade M, Martinez F, Love TE, Daniel C, Ahmed A,. Transatlantic similarities and differences in major natural history endpoints of heart failure after acute myocardial infarction: a propensity-matched study of the EPHESUS trial. Int J Cardiol 2010; 143: 309-316.
-
(2010)
Int J Cardiol
, vol.143
, pp. 309-316
-
-
Pitt, B.1
Zannad, F.2
Gheorghiade, M.3
Martinez, F.4
Love, T.E.5
Daniel, C.6
Ahmed, A.7
-
9
-
-
77953012147
-
Trends in length of stay and short-term outcomes among Medicare patients hospitalized for heart failure, 1993-2006
-
Bueno H, Ross JS, Wang Y, Chen J, Vidan MT, Normand SL, Curtis JP, Drye EE, Lichtman JH, Keenan PS, Kosiborod M, Krumholz HM,. Trends in length of stay and short-term outcomes among Medicare patients hospitalized for heart failure, 1993-2006. JAMA 2010; 303: 2141-2147.
-
(2010)
JAMA
, vol.303
, pp. 2141-2147
-
-
Bueno, H.1
Ross, J.S.2
Wang, Y.3
Chen, J.4
Vidan, M.T.5
Normand, S.L.6
Curtis, J.P.7
Drye, E.E.8
Lichtman, J.H.9
Keenan, P.S.10
Kosiborod, M.11
Krumholz, H.M.12
-
10
-
-
84884728761
-
Do countries or hospitals with longer hospital stays for acute heart failure have lower readmission rates? Findings from ASCEND-HF
-
Eapen ZJ, Reed SD, Li Y, Kociol RD, Armstrong PW, Starling RC, McMurray JJ, Massie BM, Swedberg K, Ezekowitz JA, Fonarow GC, Teerlink JR, Metra M, Whellan DJ, O'Connor CM, Califf RM, Hernandez AF,. Do countries or hospitals with longer hospital stays for acute heart failure have lower readmission rates? Findings from ASCEND-HF. Circ Heart Fail 2013; 6: 727-732.
-
(2013)
Circ Heart Fail
, vol.6
, pp. 727-732
-
-
Eapen, Z.J.1
Reed, S.D.2
Li, Y.3
Kociol, R.D.4
Armstrong, P.W.5
Starling, R.C.6
McMurray, J.J.7
Massie, B.M.8
Swedberg, K.9
Ezekowitz, J.A.10
Fonarow, G.C.11
Teerlink, J.R.12
Metra, M.13
Whellan, D.J.14
O'Connor, C.M.15
Califf, R.M.16
Hernandez, A.F.17
-
11
-
-
77957730950
-
Rolofylline, an adenosine A1-receptor antagonist, in acute heart failure
-
Massie BM, O'Connor CM, Metra M, Ponikowski P, Teerlink JR, Cotter G, Weatherley BD, Cleland JG, Givertz MM, Voors A, DeLucca P, Mansoor GA, Salerno CM, Bloomfield DM, Dittrich HC,. Rolofylline, an adenosine A1-receptor antagonist, in acute heart failure. N Engl J Med 2010; 363: 1419-1428.
-
(2010)
N Engl J Med
, vol.363
, pp. 1419-1428
-
-
Massie, B.M.1
O'Connor, C.M.2
Metra, M.3
Ponikowski, P.4
Teerlink, J.R.5
Cotter, G.6
Weatherley, B.D.7
Cleland, J.G.8
Givertz, M.M.9
Voors, A.10
Delucca, P.11
Mansoor, G.A.12
Salerno, C.M.13
Bloomfield, D.M.14
Dittrich, H.C.15
-
12
-
-
72749098775
-
Design and rationale of the PROTECT study: A placebo-controlled randomized study of the selective A1 adenosine receptor antagonist rolofylline for patients hospitalized with acute decompensated heart failure and volume overload to assess treatment effect on congestion and renal function
-
Weatherley BD, Cotter G, Dittrich HC, DeLucca P, Mansoor GA, Bloomfield DM, Ponikowski P, O'Connor CM, Metra M, Massie BM,. Design and rationale of the PROTECT study: a placebo-controlled randomized study of the selective A1 adenosine receptor antagonist rolofylline for patients hospitalized with acute decompensated heart failure and volume overload to assess treatment effect on congestion and renal function. J Card Fail 2010; 16: 25-35.
-
(2010)
J Card Fail
, vol.16
, pp. 25-35
-
-
Weatherley, B.D.1
Cotter, G.2
Dittrich, H.C.3
Delucca, P.4
Mansoor, G.A.5
Bloomfield, D.M.6
Ponikowski, P.7
O'Connor, C.M.8
Metra, M.9
Massie, B.M.10
-
13
-
-
0003068836
-
The EuroQoL instrument: An index of health-related quality of life
-
Spiker B. ed. 2nd ed. Philadelphia, PA: Lippincott-Raven;. p191- 201.
-
Kind P., The EuroQoL instrument: an index of health-related quality of life. In:, Spiker B, ed. Quality of Life and Pharmacoeconomics in Clinical Trials. 2nd ed. Philadelphia, PA: Lippincott-Raven; 1996. p191- 201.
-
(1996)
Quality of Life and Pharmacoeconomics in Clinical Trials
-
-
Kind, P.1
-
14
-
-
0031279593
-
Modeling Valuations for EuroQol Health States
-
Dolan P,. Modeling valuations for EuroQol health states. Med Care 1997; 35: 1095-1108. (Pubitemid 127453463)
-
(1997)
Medical Care
, vol.35
, Issue.11
, pp. 1095-1108
-
-
Dolan, P.1
-
15
-
-
84860433449
-
Bronchodilators in heart failure patients with COPD: Is it time for a clinical trial?
-
Mentz RJ, Fiuzat M, Kraft M, Lindenfeld J, O'Connor CM,. Bronchodilators in heart failure patients with COPD: is it time for a clinical trial? J Card Fail 2012; 18: 413-422.
-
(2012)
J Card Fail
, vol.18
, pp. 413-422
-
-
Mentz, R.J.1
Fiuzat, M.2
Kraft, M.3
Lindenfeld, J.4
O'Connor, C.M.5
-
16
-
-
84859064647
-
Clinical characteristics and outcomes of hospitalized heart failure patients with systolic dysfunction and chronic obstructive pulmonary disease: Findings from OPTIMIZE-HF
-
Mentz RJ, Fiuzat M, Wojdyla DM, Chiswell K, Gheorghiade M, Fonarow GC, O'Connor CM,. Clinical characteristics and outcomes of hospitalized heart failure patients with systolic dysfunction and chronic obstructive pulmonary disease: findings from OPTIMIZE-HF. Eur J Heart Fail 2012; 14: 395-403.
-
(2012)
Eur J Heart Fail
, vol.14
, pp. 395-403
-
-
Mentz, R.J.1
Fiuzat, M.2
Wojdyla, D.M.3
Chiswell, K.4
Gheorghiade, M.5
Fonarow, G.C.6
O'Connor, C.M.7
-
17
-
-
0037454137
-
Heart failure etiology and response to milrinone in decompensated heart failure: Results from the OPTIME-CHF study
-
DOI 10.1016/S0735-1097(02)02968-6
-
Felker GM, Benza RL, Chandler AB, Leimberger JD, Cuffe MS, Califf RM, Gheorghiade M, O'Connor CM,. Heart failure etiology and response to milrinone in decompensated heart failure: results from the OPTIME-CHF study. J Am Coll Cardiol 2003; 41: 997-1003. (Pubitemid 36315544)
-
(2003)
Journal of the American College of Cardiology
, vol.41
, Issue.6
, pp. 997-1003
-
-
Felker, G.M.1
Benza, R.L.2
Chandler, A.B.3
Leimberger, J.D.4
Cuffe, M.S.5
Califf, R.M.6
Gheorghiade, M.7
O'Connor, C.M.8
-
18
-
-
84855384347
-
International variation in and factors associated with hospital readmission after myocardial infarction
-
Kociol RD, Lopes RD, Clare R, Thomas L, Mehta RH, Kaul P, Pieper KS, Hochman JS, Weaver WD, Armstrong PW, Granger CB, Patel MR,. International variation in and factors associated with hospital readmission after myocardial infarction. JAMA 2012; 307: 66-74.
-
(2012)
JAMA
, vol.307
, pp. 66-74
-
-
Kociol, R.D.1
Lopes, R.D.2
Clare, R.3
Thomas, L.4
Mehta, R.H.5
Kaul, P.6
Pieper, K.S.7
Hochman, J.S.8
Weaver, W.D.9
Armstrong, P.W.10
Granger, C.B.11
Patel, M.R.12
-
19
-
-
0037336371
-
The EuroHeart Failure survey programme - A survey on the quality of care among patients with heart failure in Europe. Part 1: Patient characteristics and diagnosis
-
DOI 10.1016/S0195-668X(02)00823-0
-
Cleland JG, Swedberg K, Follath F, Komajda M, Cohen-Solal A, Aguilar JC, Dietz R, Gavazzi A, Hobbs R, Korewicki J, Madeira HC, Moiseyev VS, Preda I, van Gilst WH, Widimsky J, Freemantle N, Eastaugh J, Mason J,. The EuroHeart Failure survey programme-a survey on the quality of care among patients with heart failure in Europe. Part 1: patient characteristics and diagnosis. Eur Heart J 2003; 24: 442-463. (Pubitemid 36286187)
-
(2003)
European Heart Journal
, vol.24
, Issue.5
, pp. 442-463
-
-
Cleland, J.G.F.1
Swedberg, K.2
Follath, F.3
Komajda, M.4
Cohen-Solal, A.5
Aguilar, J.C.6
Dietz, R.7
Gavazzi, A.8
Hobbs, R.9
Korewicki, J.10
Madeira, H.C.11
Moiseyev, V.S.12
Preda, I.13
Van Gilst, W.H.14
Widimsky, J.15
Freemantle, N.16
Eastaugh, J.17
Mason, J.18
-
20
-
-
0344806945
-
The EuroHeart Failure survey programme - A survey on the quality of care among patients with heart failure in Europe. Part 2: Treatment
-
DOI 10.1016/S0195-668X(02)00700-5
-
Komajda M, Follath F, Swedberg K, Cleland J, Aguilar JC, Cohen-Solal A, Dietz R, Gavazzi A, Van Gilst WH, Hobbs R, Korewicki J, Madeira HC, Moiseyev VS, Preda I, Widimsky J, Freemantle N, Eastaugh J, Mason J,. The EuroHeart Failure Survey programme-a survey on the quality of care among patients with heart failure in Europe. Part 2: treatment. Eur Heart J 2003; 24: 464-474. (Pubitemid 36286188)
-
(2003)
European Heart Journal
, vol.24
, Issue.5
, pp. 464-474
-
-
Komajda, M.1
Follath, F.2
Swedberg, K.3
Cleland, J.4
Aguilar, J.C.5
Cohen-Solal, A.6
Dietz, R.7
Gavazzi, A.8
Van Gilst, W.H.9
Hobbs, R.10
Korewicki, J.11
Madeira, H.C.12
Moiseyev, V.S.13
Preda, I.14
Widimsky, J.15
Freemantle, N.16
Eastaugh, J.17
Mason, J.18
-
21
-
-
84860390336
-
Influence of global region on outcomes in heart failure beta-blocker trials
-
O'Connor CM, Fiuzat M, Swedberg K, Caron M, Koch B, Carson PE, Gattis-Stough W, Davis GW, Bristow MR,. Influence of global region on outcomes in heart failure beta-blocker trials. J Am Coll Cardiol 2011; 58: 915-922.
-
(2011)
J Am Coll Cardiol
, vol.58
, pp. 915-922
-
-
O'Connor, C.M.1
Fiuzat, M.2
Swedberg, K.3
Caron, M.4
Koch, B.5
Carson, P.E.6
Gattis-Stough, W.7
Davis, G.W.8
Bristow, M.R.9
-
22
-
-
84877156715
-
Effect of oral digoxin in high-risk heart failure patients: A pre-specified subgroup analysis of the DIG trial
-
Gheorghiade M, Patel K, Filippatos G, Anker SD, van Veldhuisen DJ, Cleland JG, Metra M, Aban IB, Greene SJ, Adams KF, McMurray JJ, Ahmed A,. Effect of oral digoxin in high-risk heart failure patients: a pre-specified subgroup analysis of the DIG trial. Eur J Heart Fail 2013; 15: 551-559.
-
(2013)
Eur J Heart Fail
, vol.15
, pp. 551-559
-
-
Gheorghiade, M.1
Patel, K.2
Filippatos, G.3
Anker, S.D.4
Van Veldhuisen, D.J.5
Cleland, J.G.6
Metra, M.7
Aban, I.B.8
Greene, S.J.9
Adams, K.F.10
McMurray, J.J.11
Ahmed, A.12
-
23
-
-
77958606969
-
International variations in the clinical, diagnostic, and treatment characteristics of emergency department patients with acute heart failure syndromes
-
Collins SP, Pang PS, Lindsell CJ, Kyriacou DN, Storrow AB, Hollander JE, Douglas Kirk J, Miller CD, Nowak R, Frank Peacock W, Tavares M, Mebazaa A, Gheorghiade M,. International variations in the clinical, diagnostic, and treatment characteristics of emergency department patients with acute heart failure syndromes. Eur J Heart Fail 2010; 12: 1253-1260.
-
(2010)
Eur J Heart Fail
, vol.12
, pp. 1253-1260
-
-
Collins, S.P.1
Pang, P.S.2
Lindsell, C.J.3
Kyriacou, D.N.4
Storrow, A.B.5
Hollander, J.E.6
Douglas Kirk, J.7
Miller, C.D.8
Nowak, R.9
Frank Peacock, W.10
Tavares, M.11
Mebazaa, A.12
Gheorghiade, M.13
-
24
-
-
84873675486
-
Relationship between hospital readmission and mortality rates for patients hospitalized with acute myocardial infarction, heart failure, or pneumonia
-
Krumholz HM, Lin Z, Keenan PS, Chen J, Ross JS, Drye EE, Bernheim SM, Wang Y, Bradley EH, Han LF, Normand SL,. Relationship between hospital readmission and mortality rates for patients hospitalized with acute myocardial infarction, heart failure, or pneumonia. JAMA 2013; 309: 587-593.
-
(2013)
JAMA
, vol.309
, pp. 587-593
-
-
Krumholz, H.M.1
Lin, Z.2
Keenan, P.S.3
Chen, J.4
Ross, J.S.5
Drye, E.E.6
Bernheim, S.M.7
Wang, Y.8
Bradley, E.H.9
Han, L.F.10
Normand, S.L.11
-
25
-
-
77955292858
-
Divergent trends in survival and readmission following a hospitalization for heart failure in the Veterans Affairs health care system 2002 to 2006
-
Heidenreich PA, Sahay A, Kapoor JR, Pham MX, Massie B,. Divergent trends in survival and readmission following a hospitalization for heart failure in the Veterans Affairs health care system 2002 to 2006. J Am Coll Cardiol 2010; 56: 362-368.
-
(2010)
J Am Coll Cardiol
, vol.56
, pp. 362-368
-
-
Heidenreich, P.A.1
Sahay, A.2
Kapoor, J.R.3
Pham, M.X.4
Massie, B.5
-
26
-
-
84880055845
-
Are we targeting the right metric for heart failure? Comparison of hospital 30-day readmission rates and total episode of care inpatient days
-
e1.
-
Kociol RD, Liang L, Hernandez AF, Curtis LH, Heidenreich PA, Yancy CW, Fonarow GC, Peterson ED,. Are we targeting the right metric for heart failure? Comparison of hospital 30-day readmission rates and total episode of care inpatient days. Am Heart J 2013; 165: 987-994.e1.
-
(2013)
Am Heart J
, vol.165
, pp. 987-994
-
-
Kociol, R.D.1
Liang, L.2
Hernandez, A.F.3
Curtis, L.H.4
Heidenreich, P.A.5
Yancy, C.W.6
Fonarow, G.C.7
Peterson, E.D.8
|