Peripheral and central nervous system inhibition of 11β-hydroxysteroid dehydrogenase type 1 in man by the novel inhibitor ABT-384.

Translational psychiatry

Volumn 3, Issue , 2013, Pages

  Katz, D A ^a   Liu, W ^b   Locke, C ^b   Jacobson, P ^b   Barnes, D M ^b   Basu, R ^b   An, G ^b   Rieser, M J ^b   Daszkowski, D ^b   Groves, F ^b   Heneghan, G ^b   Shah, A ^b   Gevorkyan, H ^b   Jhee, S S ^b   Ereshefsky, L ^b   Marek, G J ^b  

^a ABBVIE INC   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE 1; ADAMANTANE; DRUG DERIVATIVE; HYDROCORTISONE; HYDROGEN; ISOTOPE; N (5 (AMINOCARBONYL)TRICYCLO(3.3.1.13,7)DEC 2 YL) ALPHA,ALPHA DIMETHYL 4 (5 (TRIFLUOROMETHYL) 2 PYRIDINYL) 1 PIPERAZINEACETAMIDE; N-(5-(AMINOCARBONYL)TRICYCLO(3.3.1.13,7)DEC-2-YL)-ALPHA,ALPHA-DIMETHYL-4-(5-(TRIFLUOROMETHYL)-2-PYRIDINYL)-1-PIPERAZINEACETAMIDE; PIPERAZINE DERIVATIVE;

ADULT; ARTICLE; BLOOD; CENTRAL NERVOUS SYSTEM; CEREBROSPINAL FLUID; CLINICAL TRIAL; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; HUMAN; MALE; METABOLISM; MIDDLE AGED;

11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1; ADAMANTANE; ADULT; CENTRAL NERVOUS SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; HYDROCORTISONE; HYDROGEN; ISOTOPES; MALE; MIDDLE AGED; PIPERAZINES;

EID: 84901860544     PISSN: None     EISSN: 21583188     Source Type: Journal    
DOI: 10.1038/tp.2013.67     Document Type: Article

References (0)