KLF8 and FAK cooperatively enrich the active MMP14 on the cell surface required for the metastatic progression of breast cancer

Oncogene

Volumn 33, Issue 22, 2014, Pages 2909-2917

  Lu, H ^a   Hu, L ^a   Yu, L ^a   Wang, X ^a   Urvalek, A M ^a,b   Li, T ^a   Shen, C ^a   Mukherjee, D ^a   Lahiri, S K ^a   Wason, M S ^a   Zhao, J ^a  

^a UNIVERSITY OF CENTRAL FLORIDA COLLEGE OF MEDICINE   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

breast cancer; FAK; KLF8; metastasis; MMP14; catenin TCF1

Indexed keywords

BETA CATENIN; FOCAL ADHESION KINASE; KRUPPEL LIKE FACTOR; KRUPPEL LIKE FACTOR 8; MATRIX METALLOPROTEINASE 14; TRANSCRIPTION FACTOR 7; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER CELL LINE; BREAST METASTASIS; CANCER CELL; CELL INVASION; CELL SURFACE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GENE SILENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LUNG METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RNA INTERFERENCE; TRANSACTIVATION; TRANSCRIPTION REGULATION; TUMOR INVASION; UPREGULATION;

MUS;

ANIMALS; BETA CATENIN; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MEMBRANE; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; FEMALE; FOCAL ADHESION KINASE 1; GENE EXPRESSION; HEPATOCYTE NUCLEAR FACTOR 1-ALPHA; HETEROGRAFTS; HUMANS; LUNG NEOPLASMS; MATRIX METALLOPROTEINASE 14; MICE; MODELS, BIOLOGICAL; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; PROTEIN BINDING; REPRESSOR PROTEINS; TRANSCRIPTION, GENETIC;

EID: 84901844749     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2013.247     Document Type: Article

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